RU2126379C1 - ПРОИЗВОДНЫЕ ЦИКЛОПЕНТАН- ИЛИ ЦИКЛОПЕНТЕН -β- АМИНОКИСЛОТ И ИХ СОЛИ, КОМПОЗИЦИЯ, АКТИВНАЯ В ОТНОШЕНИИ ШТАММОВ S.AUREUS CANDIDA И TRICHOPHYTON - Google Patents

ПРОИЗВОДНЫЕ ЦИКЛОПЕНТАН- ИЛИ ЦИКЛОПЕНТЕН -β- АМИНОКИСЛОТ И ИХ СОЛИ, КОМПОЗИЦИЯ, АКТИВНАЯ В ОТНОШЕНИИ ШТАММОВ S.AUREUS CANDIDA И TRICHOPHYTON Download PDF

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RU2126379C1
RU2126379C1 RU93005256A RU93005256A RU2126379C1 RU 2126379 C1 RU2126379 C1 RU 2126379C1 RU 93005256 A RU93005256 A RU 93005256A RU 93005256 A RU93005256 A RU 93005256A RU 2126379 C1 RU2126379 C1 RU 2126379C1
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carbon atoms
linear
branched alkyl
hydrogen
formula
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RU93005256A
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Russian (ru)
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RU93005256A (ru
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Миттендорф Йоахим
Куниш Франц
Матцке Михаэль
Милитцер Ханс-Кристиан
Эндерманн Райнер
Георг Метцгер Карл
Бремм Клаус-Дитер
Племпель Манфред
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Байер А.Г.
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Priority claimed from DE4302155A external-priority patent/DE4302155A1/de
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU93005256A 1992-05-29 1993-05-28 ПРОИЗВОДНЫЕ ЦИКЛОПЕНТАН- ИЛИ ЦИКЛОПЕНТЕН -β- АМИНОКИСЛОТ И ИХ СОЛИ, КОМПОЗИЦИЯ, АКТИВНАЯ В ОТНОШЕНИИ ШТАММОВ S.AUREUS CANDIDA И TRICHOPHYTON RU2126379C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DEP4217776.6 1992-05-29
DE4217776A DE4217776A1 (de) 1992-05-29 1992-05-29 Cyclopentan- und penten-µ-Aminosäuren
DEP4302155.7 1993-01-27
DE4302155A DE4302155A1 (de) 1993-01-27 1993-01-27 Verwendung von Cyclopentan- und -penten-beta-Aminosäuren

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RU93005256A RU93005256A (ru) 1997-04-10
RU2126379C1 true RU2126379C1 (ru) 1999-02-20

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Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
WO1995007022A1 (en) * 1993-09-07 1995-03-16 Zeneca Limited Fungicides
DE4400749A1 (de) * 1994-01-13 1995-07-20 Bayer Ag Neues hochenantioselektives Verfahren zur Herstellung von enantiomerenreinen Cyclopentan- und -penten-beta-Aminosäuren
GB2291873A (en) * 1994-08-03 1996-02-07 Zeneca Ltd Fungicidal cyclopenta-oxazines and thiazines
DE19526274A1 (de) * 1995-07-19 1997-01-23 Bayer Ag Verbesserung der Verträglichkeit von pharmazeutisch wirksamen beta-Aminosäuren
DE19526275A1 (de) * 1995-07-19 1997-01-23 Bayer Ag Cyclopentan-beta-aminosäure-tripeptide
DE19617772A1 (de) * 1996-05-03 1997-11-13 Bayer Ag Neues effizientes und hochenantioselektives Verfahren zur Herstellung von enantiomerenreinen Cyclopentan-beta-aminosäuren
CA2258217C (en) 1996-06-14 2005-08-09 Biocryst Pharmaceuticals Inc. Substituted cyclopentane compounds useful as neuraminidase inhibitors
US6060585A (en) 1997-03-04 2000-05-09 Wisconsin Alumni Research Foundation β-polypeptide foldamers of well-defined secondary structure
CN1282316A (zh) * 1997-12-17 2001-01-31 生物晶体药品股份有限公司 用作神经氨酸酶抑制剂的取代环戊烷和环戊烯化合物
WO2000028328A1 (en) 1998-11-05 2000-05-18 Biocryst Pharmaceuticals, Inc. New cyclopentane and cyclopentene compounds and use for detecting influenza virus
WO2003008439A1 (en) * 2001-07-18 2003-01-30 Wisconsin Alumni Research Foundation ANTIMICROBIAL COMPOSITIONS CONTAINING β-AMINO ACID OLIGOMERS
US7084178B2 (en) * 2003-11-26 2006-08-01 Bristol-Myers Squibb Company Antiamyloid phenylsulfonamides: N-cycloalkylcarboxamides derivatives
FR2874014B1 (fr) * 2004-08-03 2010-05-14 Univ Paris Descartes Analogues d'aminoglycosides, leur utilisation et leur synthese
SG176056A1 (en) 2009-05-15 2011-12-29 Redx Pharma Ltd Redox drug derivatives
WO2012043802A1 (ja) * 2010-09-30 2012-04-05 日本ゼオン株式会社 シクロペンテン開環重合体およびその製造方法
EP3584290B1 (en) 2015-09-25 2021-07-21 Mitsubishi Chemical Corporation (meth)acrylic copolymer, polymer solution, polymer-containing composition, anti-fouling coating composition, and method for producing (meth)acrylic copolymer

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU608470A3 (ru) * 1975-06-09 1978-05-25 Астра Лэкемедель Аб, (Фирма) Способ получени производных циклопропанола
GB1569225A (en) * 1976-11-12 1980-06-11 Upjohn Co N-(2-aminocycloalkyl)amides
FR2362118B1 (cg-RX-API-DMAC7.html) * 1976-08-20 1981-03-06 Oreal
US5037809A (en) * 1987-07-10 1991-08-06 Fujisawa Pharmaceutical Co., Ltd. Antimicrobial agent, FR109615 and production thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1040546A (en) * 1962-12-12 1966-09-01 Ici Ltd An organic compound
HU177576B (en) * 1975-06-02 1981-11-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 2-amino-cyclohexane carboxylic acid,its amides and similar compounds
GB9108384D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Bicycloheptanes

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU608470A3 (ru) * 1975-06-09 1978-05-25 Астра Лэкемедель Аб, (Фирма) Способ получени производных циклопропанола
FR2362118B1 (cg-RX-API-DMAC7.html) * 1976-08-20 1981-03-06 Oreal
GB1569225A (en) * 1976-11-12 1980-06-11 Upjohn Co N-(2-aminocycloalkyl)amides
US5037809A (en) * 1987-07-10 1991-08-06 Fujisawa Pharmaceutical Co., Ltd. Antimicrobial agent, FR109615 and production thereof

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FI932427A0 (fi) 1993-05-27
DK0571870T3 (da) 1999-05-25
US5739160A (en) 1998-04-14
TW264461B (cg-RX-API-DMAC7.html) 1995-12-01
HRP930938A2 (en) 1996-12-31
KR100300692B1 (ko) 2001-10-22
EP0571870A1 (de) 1993-12-01
MX9303123A (es) 1993-11-01
MY128260A (en) 2007-01-31
NO931718L (no) 1993-11-30
JP3565878B2 (ja) 2004-09-15
SI9300286A (sl) 1993-12-31
PH31079A (en) 1998-02-05
DE59308884D1 (de) 1998-09-24
IL105797A (en) 1998-06-15
HUT65188A (en) 1994-05-02
FI20010045A7 (fi) 2001-01-10
AU673824B2 (en) 1996-11-28
HK1005132A1 (en) 1998-12-24
FI932427A7 (fi) 1993-11-30
CN1080634A (zh) 1994-01-12
KR930023329A (ko) 1993-12-18
EP0571870B1 (de) 1998-08-19
ATE169900T1 (de) 1998-09-15
HU9301584D0 (en) 1993-09-28
HRP930938B1 (en) 1999-12-31
SK282660B6 (sk) 2002-11-06
NO304784B1 (no) 1999-02-15
JPH0656751A (ja) 1994-03-01
NZ247715A (en) 1995-09-26
CA2097044A1 (en) 1993-11-30
FI20010045L (fi) 2001-01-10
CA2097044C (en) 2005-05-10
CN1065237C (zh) 2001-05-02
UA39918C2 (uk) 2001-07-16
NO931718D0 (no) 1993-05-11
CZ286591B6 (cs) 2000-05-17
AU3829393A (en) 1993-12-02
IL105797A0 (en) 1993-09-22
SI9300286B (en) 2001-12-31
ES2121892T3 (es) 1998-12-16
FI932427L (fi) 1993-11-30
SK55093A3 (en) 1994-01-12
CZ100893A3 (en) 1994-01-19

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