RU2070058C1 - Method of chronic bronchitis treatment - Google Patents

Abstract

FIELD: medicine, pulmonology. SUBSTANCE: method involves carrying out therapy (5 seances at 2 days interval) at initial volume of irradiated blood 0.5-0.8 ml/kg mass body at graduate increase from the third seance to 1.3-1.5 ml/kg and decrease to the fifth seance of initial level. EFFECT: decreased treatment period, prolonged remission, no antibiotics use.

Description

 The invention relates to medicine, namely to pulmonology and can be used for the rehabilitation treatment of chronic bronchitis.

 Known methods of treating chronic bronchitis using ultraviolet radiation of the skin and autohemotransfusion.

The most commonly used method for treating bronchitis involves using the effects of ultraviolet radiation on the patient’s skin daily or every other day in 1 or 2 fields. The course of treatment offers 10 15 procedures. It is assumed that due to the reflex (skin-visceral) and humoral effects (intake of biologically active substances from the skin into the blood due to photochemical reactions), a therapeutic effect occurs. But at the same time, the amount of biologically active substances is correlated with a certain dose of ultraviolet radiation, i.e., with an overdose, the formation of toxic substances is possible inverse. In addition, not all biologically active substances enter the blood, due to the resorption ability of the skin. Therefore, this method requires prolonged use and is limited by the possibility of entering the necessary amount of biologically active substances into the blood [1]
Autohemotherapy is a method of treating chronic bronchitis, which involves taking blood from a patient’s vein from 1 to 8 10 ml and administering it intramuscularly. This method is based on increasing the protective properties of the body by introducing an additional irritant into the body. However, the main disadvantage of this method is that the patient’s blood does not acquire additional qualities that enhance the therapeutic effect.

The closest to execution is the treatment course AUFOK consisting of 3 10 sessions conducted daily. The amount of irradiated blood is 1 ml / kg of patient weight. The therapeutic effect of this course of treatment is phase in nature and depends on the number of sessions [2]
The purpose of the invention is the prevention of exacerbations of chronic bronchitis and lengthening the stage of remission.

 The goal is achieved by AUFOK in a number of 5 procedures with an interval of 2 days with an initial volume of irradiated autologous blood of 0.5 0.8 ml / kg of patient weight with a gradual increase in the 3rd procedure to 1.3 1.5 ml / kg and a decrease to the 5th procedure to the initial level.

 The method is as follows. After completion of acute chronic bronchitis with exacerbation or without exacerbation, the patient’s venous blood is irradiated with the Isold apparatus for 15 minutes. The initial amount of irradiated autoblood is taken from 0.5 to 0.8 ml / kg of patient weight. By the middle of the course of treatment, i.e., to the 3rd procedure, the amount of irradiated autoblood is increased to 1.3-1.5 ml / kg of patient weight. Then, by the 5th procedure, the amount of irradiated blood is reduced to the initial level, i.e., to 0.5 0.8 ml. In total, 5 treatments with an interval of 2 days are offered for the course of treatment.

 Example 1. Patient S. 41 years old, suffers from chronic bronchitis for 10 years with frequent exacerbation of the disease up to 2 3 times a year. The patient underwent AUFOK therapy of 5 procedures at intervals of 2 days, the initial amount of irradiated autoblood in the first procedure was 0.8 ml per 1 kg of patient weight. By the third procedure, the volume of irradiated autoblood was increased to 1.3 ml per 1 kg of the patient’s weight, and by the 5th procedure this amount was again reduced to 0.8 ml. After the 3rd procedure, shortness of breath significantly decreased in the patient, and after the 5th respiratory failure decreased from II to I degree. Examination after a year showed no signs of exacerbation of the disease.

 Example 2. Patient S., 47 years old, has been suffering from chronic bronchitis with exacerbations 4–5 times a year for 15 years with long-term disability. AUFOK therapy was carried out from 5 procedures with an interval of 2 days. The amount of irradiated autoblood in the first procedure was 0.8 ml per 1 kg of patient weight, the maximum amount of irradiated blood by the 3rd procedure was 1.5 ml / kg of patient weight, and by the 5th procedure, 0.8 ml / kg. After the course of treatment, purulent sputum disappeared, shortness of breath significantly decreased, respiratory failure decreased from III to I degree. During the year, the exacerbation of the disease 2 times with short-term disability.

 Example 3. Patient W., 45 years old, suffers from chronic bronchitis for 5 years. AUFOK therapy course of 5 procedures was prescribed with an interval of 2 days. The initial amount of irradiated autologous blood is 0.5 ml / kg of the patient’s mass, the maximum amount in the 3rd procedure is 1.1 ml / kg of the patient’s mass; by the 5th procedure, 0.5 ml. During the year, there were no exacerbations of the disease, no respiratory infections.2 Treatment with the use of AUFC therapy in this way was carried out for 156 patients with chronic bronchitis. In the group of patients with purulent forms of bronchitis, purulent sputum disappeared by the 3rd procedure, intoxication symptoms disappeared, clinical, laboratory and biochemical parameters of inflammation normalized. In the group of patients with obstructive forms of chronic bronchitis, a decrease in the clinical and functional signs of obstruction was noted. In addition, in all patients there was a decrease in astheno-vegetative symptoms of the disease, improved sleep, appetite, and mental state. In 87.4% of cases, the effect of treatment was noted according to clinical, clinical, laboratory, biochemical, and functional indicators.

 The proposed method allows to eliminate the phenomenon of exacerbation of the disease without the use of antibiotics and significantly reduce the duration of treatment, as well as to extend the stage of remission.

Claims (1)

 A method for the treatment of chronic bronchitis by reinfusion of the blood irradiated with ultraviolet radiation, characterized in that the reinfusion of the irradiated blood is carried out with a change in the volume of reinfused blood from 0.5 ml / kg of the patient's weight in the first session to 1.5 ml / kg of weight in the third session and up to 0.5 ml / kg of weight in the fifth session.