RU2033165C1 - Способ получения пластичного материала из коллагена - Google Patents
Способ получения пластичного материала из коллагена Download PDFInfo
- Publication number
- RU2033165C1 RU2033165C1 SU894745668A SU4745668A RU2033165C1 RU 2033165 C1 RU2033165 C1 RU 2033165C1 SU 894745668 A SU894745668 A SU 894745668A SU 4745668 A SU4745668 A SU 4745668A RU 2033165 C1 RU2033165 C1 RU 2033165C1
- Authority
- RU
- Russia
- Prior art keywords
- solution
- gel
- washing
- collagen
- water
- Prior art date
Links
- 239000000463 material Substances 0.000 title claims abstract description 16
- 102000008186 Collagen Human genes 0.000 title claims abstract description 8
- 108010035532 Collagen Proteins 0.000 title claims abstract description 8
- 229920001436 collagen Polymers 0.000 title claims abstract description 8
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 229920003023 plastic Polymers 0.000 title claims 2
- 238000000034 method Methods 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000008367 deionised water Substances 0.000 claims abstract description 6
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 6
- 230000035699 permeability Effects 0.000 claims abstract description 6
- 238000005406 washing Methods 0.000 claims abstract description 5
- 239000000178 monomer Substances 0.000 claims abstract description 4
- 229910052751 metal Inorganic materials 0.000 claims abstract description 3
- 239000002184 metal Substances 0.000 claims abstract description 3
- 239000000047 product Substances 0.000 claims abstract 3
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims abstract 2
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims abstract 2
- 229920002554 vinyl polymer Polymers 0.000 claims abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- 239000012153 distilled water Substances 0.000 claims description 4
- 206010011033 Corneal oedema Diseases 0.000 claims description 3
- 102000004142 Trypsin Human genes 0.000 claims description 3
- 108090000631 Trypsin Proteins 0.000 claims description 3
- 201000004778 corneal edema Diseases 0.000 claims description 3
- 239000007789 gas Substances 0.000 claims description 3
- 210000003786 sclera Anatomy 0.000 claims description 3
- 239000012588 trypsin Substances 0.000 claims description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 238000005119 centrifugation Methods 0.000 claims 2
- 238000000227 grinding Methods 0.000 claims 2
- 239000012535 impurity Substances 0.000 claims 2
- -1 tissue grinding Substances 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 1
- 239000003513 alkali Substances 0.000 claims 1
- 238000000502 dialysis Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 238000000265 homogenisation Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 230000020477 pH reduction Effects 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 claims 1
- 239000006228 supernatant Substances 0.000 claims 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract description 4
- 238000003756 stirring Methods 0.000 abstract description 4
- 150000001768 cations Chemical class 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 230000005855 radiation Effects 0.000 abstract description 2
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 abstract description 2
- 150000001450 anions Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 230000035614 depigmentation Effects 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000009738 saturating Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 2
- 239000004327 boric acid Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 210000004087 cornea Anatomy 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 210000000795 conjunctiva Anatomy 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000002344 fibroplastic effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 210000004969 inflammatory cell Anatomy 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 description 1
- 210000003024 peritoneal macrophage Anatomy 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F292/00—Macromolecular compounds obtained by polymerising monomers on to inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Zoology (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Graft Or Block Polymers (AREA)
- Materials For Medical Uses (AREA)
- Eyeglasses (AREA)
- Polymerisation Methods In General (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU894745668A RU2033165C1 (ru) | 1989-10-13 | 1989-10-13 | Способ получения пластичного материала из коллагена |
| DE4020625A DE4020625A1 (de) | 1989-10-13 | 1990-06-28 | Biologisch vertraegliches polymeres material und dessen herstellungsverfahren |
| US07/549,452 US5286829A (en) | 1989-10-13 | 1990-07-06 | Biocompatible polymer material and a process for producing same |
| JP2185439A JPH07114802B2 (ja) | 1989-10-13 | 1990-07-16 | 生物適合性ポリマー材料及びその製造方法 |
| SE9002459A SE9002459L (sv) | 1989-10-13 | 1990-07-18 | Biofoerenligt polymert material och foerfarande foer framstaellning av detsamma |
| CN90109120A CN1051918A (zh) | 1989-10-13 | 1990-10-11 | 生物相容高分子材料的制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU894745668A RU2033165C1 (ru) | 1989-10-13 | 1989-10-13 | Способ получения пластичного материала из коллагена |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2033165C1 true RU2033165C1 (ru) | 1995-04-20 |
Family
ID=21472834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU894745668A RU2033165C1 (ru) | 1989-10-13 | 1989-10-13 | Способ получения пластичного материала из коллагена |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5286829A (enExample) |
| JP (1) | JPH07114802B2 (enExample) |
| CN (1) | CN1051918A (enExample) |
| DE (1) | DE4020625A1 (enExample) |
| RU (1) | RU2033165C1 (enExample) |
| SE (1) | SE9002459L (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2139017C1 (ru) * | 1997-10-23 | 1999-10-10 | Общество с ограниченной ответственностью Научно-экспериментальное производство "Микрохирургия глаза" | Способ получения биосовместимого материала |
| RU2150956C1 (ru) * | 1999-06-24 | 2000-06-20 | Общество с ограниченной ответственностью "Научно-экспериментальное производство "Микрохирургия глаза" | Способ получения биосовместимого материала |
| RU2161976C1 (ru) * | 2000-04-21 | 2001-01-20 | Панасюк Андрей Федорович | Способ получения коллагена из костной ткани |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5322889A (en) * | 1991-09-24 | 1994-06-21 | Mitsubishi Rayon Co., Ltd. | Composite composition having high transparency and process for producing same |
| US5693085A (en) | 1994-04-29 | 1997-12-02 | Scimed Life Systems, Inc. | Stent with collagen |
| US5661218A (en) * | 1994-07-22 | 1997-08-26 | Staar Surgical Company, Inc. | Biocompatible optically transparent polymeric material based upon collagen and method of making |
| ES2200001T3 (es) * | 1994-07-22 | 2004-03-01 | Staar Surgical Company, Inc. | Material polimerico biocompatible opticamente transparente basado en colageno y metodo de elaboracion. |
| RU2084468C1 (ru) * | 1995-02-17 | 1997-07-20 | Межотраслевой научно-технический комплекс "Микрохирургия глаза" | Способ получения биосовместимого полимерного материала |
| WO1996040818A1 (en) * | 1995-06-07 | 1996-12-19 | Vladimir Feingold | Biocompatible optically transparent polymeric material based upon collagen and method of making |
| US6432137B1 (en) | 1999-09-08 | 2002-08-13 | Medennium, Inc. | High refractive index silicone for use in intraocular lenses |
| US20080081851A1 (en) * | 2006-09-01 | 2008-04-03 | Benz Patrick H | Optical polymers with higher refractive index |
| US8506944B2 (en) | 2008-05-07 | 2013-08-13 | The Regents Of The University Of California | Replenishment and enrichment of ocular surface lubrication |
| CN105664136A (zh) * | 2008-05-07 | 2016-06-15 | 加利福尼亚大学董事会 | 眼表润滑的治疗性补充和富集 |
| AU2015203038B2 (en) * | 2010-02-08 | 2017-02-23 | Regents Of The University Of Minnesota | Silica-based composite ocular device and methods |
| EP2533822A2 (en) * | 2010-02-08 | 2012-12-19 | Regents Of The University Of Minnesota | Silica-based composite ocular device and methods |
| US12127934B2 (en) | 2014-09-09 | 2024-10-29 | Staar Surgical Company | Method of Providing Modified Monovision to a Subject with a First Lens and a Second Lens |
| CA2960503C (en) | 2014-09-09 | 2022-01-25 | Staar Surgical Company | Ophthalmic implants with extended depth of field and enhanced distance visual acuity |
| WO2017156077A1 (en) | 2016-03-09 | 2017-09-14 | Staar Surgical Company | Ophthalmic implants with extended depth of field and enhanced distance visual acuity |
| US10774164B2 (en) | 2018-08-17 | 2020-09-15 | Staar Surgical Company | Polymeric composition exhibiting nanogradient of refractive index |
| US12295829B2 (en) | 2021-10-04 | 2025-05-13 | Staar Surgical Company | Ophthalmic implants for correcting vision with a tunable optic, and methods of manufacture and use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4687820A (en) * | 1984-08-22 | 1987-08-18 | Cuno Incorporated | Modified polypeptide supports |
| US4731080A (en) * | 1985-01-18 | 1988-03-15 | Galin Miles A | Coated intraocular lens |
| US4978352A (en) * | 1989-06-07 | 1990-12-18 | Fedorov Svjatoslav N | Process for producing collagen-based cross-linked biopolymer, an implant from said biopolymer, method for producing said implant, and method for hermetization of corneal or scleral wounds involved in eye injuries, using said implant |
-
1989
- 1989-10-13 RU SU894745668A patent/RU2033165C1/ru active
-
1990
- 1990-06-28 DE DE4020625A patent/DE4020625A1/de active Granted
- 1990-07-06 US US07/549,452 patent/US5286829A/en not_active Expired - Fee Related
- 1990-07-16 JP JP2185439A patent/JPH07114802B2/ja not_active Expired - Lifetime
- 1990-07-18 SE SE9002459A patent/SE9002459L/xx not_active Application Discontinuation
- 1990-10-11 CN CN90109120A patent/CN1051918A/zh active Pending
Non-Patent Citations (1)
| Title |
|---|
| Авторское свидетельство СССР N 1747075, кл. A 61K 35/44, 1987. * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2139017C1 (ru) * | 1997-10-23 | 1999-10-10 | Общество с ограниченной ответственностью Научно-экспериментальное производство "Микрохирургия глаза" | Способ получения биосовместимого материала |
| RU2150956C1 (ru) * | 1999-06-24 | 2000-06-20 | Общество с ограниченной ответственностью "Научно-экспериментальное производство "Микрохирургия глаза" | Способ получения биосовместимого материала |
| RU2161976C1 (ru) * | 2000-04-21 | 2001-01-20 | Панасюк Андрей Федорович | Способ получения коллагена из костной ткани |
Also Published As
| Publication number | Publication date |
|---|---|
| SE9002459L (sv) | 1991-04-14 |
| CN1051918A (zh) | 1991-06-05 |
| DE4020625A1 (de) | 1991-04-18 |
| US5286829A (en) | 1994-02-15 |
| SE9002459D0 (sv) | 1990-07-18 |
| JPH03146066A (ja) | 1991-06-21 |
| DE4020625C2 (enExample) | 1993-04-15 |
| JPH07114802B2 (ja) | 1995-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2033165C1 (ru) | Способ получения пластичного материала из коллагена | |
| SU1321420A1 (ru) | Способ изготовлени коллагенового покрыти дл использовани в офтальмологии | |
| US5374663A (en) | Process for producing cyanopsia-correctable intraocular lens | |
| CA1158463A (en) | Collagen contact lens | |
| US3831604A (en) | Method of reshaping the cornea | |
| US4349470A (en) | Protein polymer hydrogels | |
| US4321261A (en) | Ionic ophthalmic solutions | |
| US3873467A (en) | Hematologic reference control | |
| US4416814A (en) | Protein polymer hydrogels | |
| CN107118359B (zh) | 光固化水凝胶及其制备方法 | |
| US4912141A (en) | Fibrous and cartilaginous tissue replacement | |
| EP0359829B1 (en) | Process for producing intraocular lens for correcting cyanopia | |
| JPH01298312A (ja) | 細孔化コンタクトレンズの製造法 | |
| RU2089198C1 (ru) | Способ получения биоматериала для использования в офтальмологии | |
| US5993796A (en) | Biocompatible polymeric materials, methods of preparing such materials and uses thereof | |
| JPH0271751A (ja) | 非架橋ヒドロゲル、それの調製方法、並びにその内科用および／または外科用用品としての使用 | |
| JPH06337378A (ja) | 抗菌性ハイドロゲルおよびそれを含む抗菌性ソフトコンタクトレンズ | |
| CN115128839B (zh) | 一种基于天然蚕丝制备丝素蛋白隐形眼镜的方法 | |
| US3822196A (en) | Fabrication of soft plastic contact lens blank and composition therefor | |
| CA1312827C (en) | Bone and bony tissue replacement | |
| CN109180964A (zh) | 一种丝素蛋白光固化水凝胶及其制备方法 | |
| RU2058328C1 (ru) | Способ получения полимерного материала для мягких контактных линз | |
| EP0077295A1 (de) | Kontaktlinse aus mit Borat vernetztem Polyvinylalkohol | |
| JPH1152303A (ja) | 天然生体高分子を含有するコンタクトレンズ及びその製造方法 | |
| JP2529538B2 (ja) | コンタクトレンズ及びその製造方法 |