RU2019144107A3 - - Google Patents

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Publication number
RU2019144107A3
RU2019144107A3 RU2019144107A RU2019144107A RU2019144107A3 RU 2019144107 A3 RU2019144107 A3 RU 2019144107A3 RU 2019144107 A RU2019144107 A RU 2019144107A RU 2019144107 A RU2019144107 A RU 2019144107A RU 2019144107 A3 RU2019144107 A3 RU 2019144107A3
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RU
Russia
Application number
RU2019144107A
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Russian (ru)
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RU2019144107A (ru
RU2773943C2 (ru
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Publication of RU2019144107A publication Critical patent/RU2019144107A/ru
Publication of RU2019144107A3 publication Critical patent/RU2019144107A3/ru
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Publication of RU2773943C2 publication Critical patent/RU2773943C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/14—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from hepatocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU2019144107A 2017-06-09 2018-06-07 Соединения и композиции для индуцирования хондрогенеза RU2773943C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762517394P 2017-06-09 2017-06-09
US62/517,394 2017-06-09
PCT/IB2018/054123 WO2018225009A1 (en) 2017-06-09 2018-06-07 Compounds and compositions for inducing chondrogenesis

Publications (3)

Publication Number Publication Date
RU2019144107A RU2019144107A (ru) 2021-07-09
RU2019144107A3 true RU2019144107A3 (enExample) 2021-07-30
RU2773943C2 RU2773943C2 (ru) 2022-06-14

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Also Published As

Publication number Publication date
EP4299123A2 (en) 2024-01-03
EP4299123A3 (en) 2024-04-03
TW201902900A (zh) 2019-01-16
MX389169B (es) 2025-03-20
JOP20190282B1 (ar) 2024-04-18
IL300755A (en) 2023-04-01
CN110719913A (zh) 2020-01-21
JP7432778B2 (ja) 2024-02-16
NZ759434A (en) 2024-01-26
CO2019013706A2 (es) 2020-04-01
PH12019502764A1 (en) 2020-07-13
AU2018279306A1 (en) 2019-12-05
US20210079010A1 (en) 2021-03-18
HRP20240155T1 (hr) 2024-04-12
CN110719913B (zh) 2022-10-28
PE20200403A1 (es) 2020-02-26
CU24577B1 (es) 2022-02-04
EP3634967A1 (en) 2020-04-15
MA50547A (fr) 2020-09-16
BR112019025866A2 (pt) 2020-07-14
CR20190551A (es) 2020-01-28
KR102656524B1 (ko) 2024-04-12
FI3915994T3 (fi) 2024-02-14
MA57022B1 (fr) 2024-02-29
IL271154B2 (en) 2023-07-01
JP2023062064A (ja) 2023-05-02
SA519410729B1 (ar) 2022-07-03
PT3915994T (pt) 2024-02-15
JP7229945B2 (ja) 2023-02-28
JOP20190282A1 (ar) 2019-12-05
DOP2019000305A (es) 2019-01-15
TWI782036B (zh) 2022-11-01
ES2971319T3 (es) 2024-06-04
US20230365580A1 (en) 2023-11-16
IL271154B1 (en) 2023-03-01
WO2018225009A1 (en) 2018-12-13
PL3915994T3 (pl) 2024-05-20
EP3915994A1 (en) 2021-12-01
KR20200013046A (ko) 2020-02-05
US20210347784A1 (en) 2021-11-11
CU20190098A7 (es) 2020-10-20
US12209096B2 (en) 2025-01-28
EP3915994B9 (en) 2024-02-28
AU2018279306C1 (en) 2021-01-14
MX2019014757A (es) 2020-02-12
AU2018279306B2 (en) 2020-07-09
AR113227A1 (es) 2020-02-19
DK3915994T3 (da) 2024-02-19
MY198288A (en) 2023-08-21
CL2019003564A1 (es) 2020-06-19
ZA201907358B (en) 2022-04-28
US11753416B2 (en) 2023-09-12
UY37759A (es) 2019-01-31
IL271154A (en) 2020-01-30
EA201992858A1 (ru) 2020-04-02
EP3915994B1 (en) 2023-11-22
CA3063985A1 (en) 2018-12-13
RU2019144107A (ru) 2021-07-09
RS65161B1 (sr) 2024-02-29
JP2020522550A (ja) 2020-07-30
HUE065194T2 (hu) 2024-05-28
SI3915994T1 (sl) 2024-03-29
LT3915994T (lt) 2024-02-26
US11091499B2 (en) 2021-08-17
ECSP19086712A (es) 2019-12-27

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