RU2019131098A3 - - Google Patents
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- Publication number
- RU2019131098A3 RU2019131098A3 RU2019131098A RU2019131098A RU2019131098A3 RU 2019131098 A3 RU2019131098 A3 RU 2019131098A3 RU 2019131098 A RU2019131098 A RU 2019131098A RU 2019131098 A RU2019131098 A RU 2019131098A RU 2019131098 A3 RU2019131098 A3 RU 2019131098A3
- Authority
- RU
- Russia
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1705484.2 | 2017-04-05 | ||
| GBGB1705484.2A GB201705484D0 (en) | 2017-04-05 | 2017-04-05 | Genetic construct |
| PCT/GB2018/050824 WO2018185468A1 (en) | 2017-04-05 | 2018-03-28 | Genetic construct for use in the treatment of neurodegenerative disorder or stroke |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2019131098A RU2019131098A (ru) | 2021-05-05 |
| RU2019131098A3 true RU2019131098A3 (ru) | 2021-07-27 |
| RU2757932C2 RU2757932C2 (ru) | 2021-10-25 |
Family
ID=58682577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019131098A RU2757932C2 (ru) | 2017-04-05 | 2018-03-28 | Генетическая конструкция для применения при лечении нейродегенеративного нарушения или инсульта |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20200046850A1 (ru) |
| EP (1) | EP3606546B1 (ru) |
| JP (1) | JP7296321B2 (ru) |
| KR (1) | KR102616629B1 (ru) |
| CN (1) | CN110809476B (ru) |
| AU (1) | AU2018248651A1 (ru) |
| CA (1) | CA3058549A1 (ru) |
| ES (1) | ES2881176T3 (ru) |
| GB (1) | GB201705484D0 (ru) |
| MX (1) | MX2019012000A (ru) |
| PL (1) | PL3606546T3 (ru) |
| PT (1) | PT3606546T (ru) |
| RU (1) | RU2757932C2 (ru) |
| WO (1) | WO2018185468A1 (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3898982A2 (en) * | 2018-12-19 | 2021-10-27 | Versameb AG | Rna encoding a protein |
| EP3936152A4 (en) | 2019-03-04 | 2022-12-07 | Tokyo Metropolitan Institute of Medical Science | NUCLEIC ACID CONSTRUCT FOR ENCODING AND USING A TRK FRAGMENT |
| CN113840620A (zh) * | 2019-03-27 | 2021-12-24 | 西吉隆医疗股份有限公司 | 用于治疗法布里病的组合物、装置和方法 |
| GB202004832D0 (en) * | 2020-04-01 | 2020-05-13 | Instituto De Medicina Molecular Faculdade De Medicina Univ De Lisboa | Therapeutic agaents, pharmaceutical compositions, and associated biomarkers |
| CN114933657B (zh) * | 2021-08-25 | 2024-02-02 | 上海交通大学医学院 | 神经生长因子突变体重组蛋白及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2588221C (en) * | 1999-06-08 | 2013-07-09 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
| US20030124095A1 (en) * | 2001-12-31 | 2003-07-03 | Regents Of The University Of California | Methods for therapeutic use of brain derived neurotrophic factor in the entorhinal cortex |
| US9265843B2 (en) | 2008-03-27 | 2016-02-23 | The Ohio State University | Treatment of metabolic-related disorders using hypothalamic gene transfer of BDNF and compositions therefor |
| US8703125B2 (en) * | 2008-12-19 | 2014-04-22 | H. Lundbeck A/S | Modulation of the Vps10p-domain receptor family for the treatment of mental and behavioural disorders |
| HUE040179T2 (hu) * | 2012-03-15 | 2019-02-28 | Curna Inc | Agyi eredetû neutrotróf faktorral (Brain-derived neurotrophic factor, BDNF) összefüggõ betegségek kezelése a BDNF-fel kapcsolatos természetes antiszensz transzkriptumok gátlása révén |
| GB2547179A (en) * | 2015-10-26 | 2017-08-16 | Quethera Ltd | Genetic construct |
-
2017
- 2017-04-05 GB GBGB1705484.2A patent/GB201705484D0/en not_active Ceased
-
2018
- 2018-03-28 PL PL18715911T patent/PL3606546T3/pl unknown
- 2018-03-28 EP EP18715911.6A patent/EP3606546B1/en active Active
- 2018-03-28 MX MX2019012000A patent/MX2019012000A/es unknown
- 2018-03-28 US US16/497,412 patent/US20200046850A1/en not_active Abandoned
- 2018-03-28 PT PT187159116T patent/PT3606546T/pt unknown
- 2018-03-28 ES ES18715911T patent/ES2881176T3/es active Active
- 2018-03-28 AU AU2018248651A patent/AU2018248651A1/en active Pending
- 2018-03-28 WO PCT/GB2018/050824 patent/WO2018185468A1/en unknown
- 2018-03-28 RU RU2019131098A patent/RU2757932C2/ru active
- 2018-03-28 CA CA3058549A patent/CA3058549A1/en active Pending
- 2018-03-28 KR KR1020197032606A patent/KR102616629B1/ko active IP Right Grant
- 2018-03-28 CN CN201880023931.XA patent/CN110809476B/zh active Active
- 2018-03-28 JP JP2019554630A patent/JP7296321B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20200005549A (ko) | 2020-01-15 |
| WO2018185468A1 (en) | 2018-10-11 |
| MX2019012000A (es) | 2020-01-27 |
| ES2881176T3 (es) | 2021-11-29 |
| JP7296321B2 (ja) | 2023-06-22 |
| EP3606546A1 (en) | 2020-02-12 |
| GB201705484D0 (en) | 2017-05-17 |
| KR102616629B1 (ko) | 2023-12-21 |
| EP3606546B1 (en) | 2021-04-28 |
| US20200046850A1 (en) | 2020-02-13 |
| RU2019131098A (ru) | 2021-05-05 |
| JP2020516244A (ja) | 2020-06-11 |
| PT3606546T (pt) | 2021-07-12 |
| AU2018248651A1 (en) | 2019-10-17 |
| CN110809476A (zh) | 2020-02-18 |
| RU2757932C2 (ru) | 2021-10-25 |
| CA3058549A1 (en) | 2018-10-11 |
| CN110809476B (zh) | 2024-02-27 |
| PL3606546T3 (pl) | 2021-11-08 |