RU2019116786A3 - - Google Patents
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- RU2019116786A3 RU2019116786A3 RU2019116786A RU2019116786A RU2019116786A3 RU 2019116786 A3 RU2019116786 A3 RU 2019116786A3 RU 2019116786 A RU2019116786 A RU 2019116786A RU 2019116786 A RU2019116786 A RU 2019116786A RU 2019116786 A3 RU2019116786 A3 RU 2019116786A3
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Data Mining & Analysis (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Databases & Information Systems (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioethics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Computation (AREA)
- Software Systems (AREA)
- Artificial Intelligence (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Sustainable Development (AREA)
- Primary Health Care (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016-213690 | 2016-10-31 | ||
| JP2016213690 | 2016-10-31 | ||
| PCT/JP2017/039363 WO2018079840A1 (ja) | 2016-10-31 | 2017-10-31 | 疾患の罹患判定装置、疾患の罹患判定方法及び疾患の罹患判定プログラム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2019116786A RU2019116786A (ru) | 2020-11-30 |
| RU2019116786A3 true RU2019116786A3 (ru) | 2020-11-30 |
| RU2765695C2 RU2765695C2 (ru) | 2022-02-02 |
Family
ID=61195694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019116786A RU2765695C2 (ru) | 2016-10-31 | 2017-10-31 | Устройство определения поражения заболеванием, способ определения поражения заболеванием и программа определения поражения заболеванием |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20190267113A1 (ru) |
| EP (1) | EP3534281A4 (ru) |
| JP (3) | JP6280997B1 (ru) |
| CN (1) | CN109923614A (ru) |
| RU (1) | RU2765695C2 (ru) |
| WO (1) | WO2018079840A1 (ru) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010242036A1 (en) | 2009-04-30 | 2011-11-03 | Patientslikeme, Inc. | Systems and methods for encouragement of data submission in online communities |
| US11250340B2 (en) * | 2017-12-14 | 2022-02-15 | Microsoft Technology Licensing, Llc | Feature contributors and influencers in machine learned predictive models |
| JP6879239B2 (ja) * | 2018-03-14 | 2021-06-02 | オムロン株式会社 | 異常検知システム、サポート装置およびモデル生成方法 |
| WO2020008502A1 (ja) * | 2018-07-02 | 2020-01-09 | シンセティックゲシュタルト エルティーディー | 情報処理システム、情報処理装置、サーバ装置、プログラム、又は方法 |
| JP7362241B2 (ja) * | 2018-11-02 | 2023-10-17 | 公益財団法人がん研究会 | 大腸がんの検査方法 |
| US11151420B2 (en) * | 2018-11-19 | 2021-10-19 | International Business Machines Corporation | Determination using learned model |
| EP3865872A4 (en) | 2018-11-19 | 2022-08-10 | Canon Kabushiki Kaisha | INFORMATION PROCESSING DEVICE, METHOD FOR CONTROLLING AN INFORMATION PROCESSING DEVICE, PROGRAM, CALCULATION DEVICE AND CALCULATION METHOD |
| US11894139B1 (en) * | 2018-12-03 | 2024-02-06 | Patientslikeme Llc | Disease spectrum classification |
| CN110211690A (zh) * | 2019-04-19 | 2019-09-06 | 平安科技（深圳）有限公司 | 疾病风险预测方法、装置、计算机设备及计算机存储介质 |
| JPWO2020222287A1 (ru) * | 2019-04-29 | 2020-11-05 | ||
| JP6884810B2 (ja) * | 2019-05-08 | 2021-06-09 | キユーピー株式会社 | 情報提供装置、情報提供方法及びｍｉＲＮＡ重要度テーブル生成方法 |
| CN110338843A (zh) * | 2019-08-02 | 2019-10-18 | 无锡海斯凯尔医学技术有限公司 | 组织评价方法、装置、设备及计算机可读存储介质 |
| CN110327074A (zh) * | 2019-08-02 | 2019-10-15 | 无锡海斯凯尔医学技术有限公司 | 肝脏评价方法、装置、设备及计算机可读存储介质 |
| JP7412150B2 (ja) * | 2019-11-29 | 2024-01-12 | 東京エレクトロン株式会社 | 予測装置、予測方法及び予測プログラム |
| JP7452990B2 (ja) * | 2019-11-29 | 2024-03-19 | 東京エレクトロン株式会社 | 異常検知装置、異常検知方法及び異常検知プログラム |
| WO2021142417A2 (en) * | 2020-01-10 | 2021-07-15 | Bisquertt Alejandro | Systems for detecting alzheimer's disease |
| CN111312401B (zh) * | 2020-01-14 | 2021-12-17 | 之江实验室 | 一种基于多标签学习的体检后慢性疾病预后系统 |
| JP7551096B2 (ja) | 2020-03-31 | 2024-09-17 | 国立大学法人神戸大学 | 酵素反応阻害パターンが疾患のバイオマーカーとして利用できるかを調べる方法および装置、並びに、疾患検査装置 |
| US11468276B2 (en) * | 2020-04-16 | 2022-10-11 | Robert Bosch Gmbh | System and method of a monotone operator neural network |
| CN111696662A (zh) * | 2020-05-26 | 2020-09-22 | 平安科技（深圳）有限公司 | 疾病预测方法、装置及存储介质 |
| CN112530595A (zh) * | 2020-12-21 | 2021-03-19 | 无锡市第二人民医院 | 一种基于多分支链式神经网络的心血管疾病分类方法和装置 |
| CN112685561A (zh) * | 2020-12-26 | 2021-04-20 | 广州知汇云科技有限公司 | 一种跨病种的小样本临床医疗文本后结构化处理方法 |
| EP4411742A1 (en) * | 2021-09-29 | 2024-08-07 | FUJIFILM Corporation | Measurable and preferable feature selection method, program for selecting measurable and preferable feature, and measurable and preferable feature selection device |
| JP7374424B2 (ja) * | 2021-11-30 | 2023-11-07 | ダイキン工業株式会社 | 疾病あるいは健康状態の検査方法、及び検査システム |
| CN114613438B (zh) * | 2022-03-08 | 2023-05-26 | 电子科技大学 | 一种miRNA与疾病的关联预测方法及系统 |
| KR20240092770A (ko) * | 2022-12-15 | 2024-06-24 | 한국과학기술원 | 우울증 예측을 위한 인공지능 및 웹 기반 플랫폼 |
| CN116578711B (zh) * | 2023-07-06 | 2023-10-27 | 武汉楚精灵医疗科技有限公司 | 腹痛特征提取方法、装置、电子设备及存储介质 |
| CN118609668A (zh) * | 2024-06-25 | 2024-09-06 | 云鉴康(杭州)医疗科技有限公司 | 基于深度学习质谱分类方法、生物标志物发现方法及装置 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1194045A (zh) * | 1995-07-25 | 1998-09-23 | 好乐思治疗公司 | 计算机辅助疾病诊断方法 |
| EP0879449A2 (en) * | 1996-02-09 | 1998-11-25 | Adeza Biomedical Corporation | Method for selecting medical and biochemical diagnostic tests using neural network-related applications |
| JP3525082B2 (ja) * | 1999-09-16 | 2004-05-10 | 日本電信電話株式会社 | 統計モデル作成方法 |
| JP2003006329A (ja) * | 2001-06-26 | 2003-01-10 | Hitachi Ltd | 診断支援システム |
| JP3823192B2 (ja) * | 2002-04-19 | 2006-09-20 | 学校法人慶應義塾 | 診療支援装置、診療支援方法、及び診療支援プログラム |
| US7774143B2 (en) * | 2002-04-25 | 2010-08-10 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Methods for analyzing high dimensional data for classifying, diagnosing, prognosticating, and/or predicting diseases and other biological states |
| US20040219575A1 (en) * | 2002-12-26 | 2004-11-04 | Toomas Neuman | Methods and compositions for the diagnosis, prognosis, and treatment of cancer |
| EP1633234A4 (en) * | 2003-06-03 | 2009-05-13 | Physiosonics Inc | SYSTEMS AND METHODS FOR DETERMINING INTRACRANIAL FA NON-INVASIVE PRESSURE AND ACOUSTIC TRANSDUCER ASSEMBLIES FOR USE THEREIN |
| CA2531967C (en) * | 2003-07-10 | 2013-07-16 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| JP5038671B2 (ja) * | 2006-09-25 | 2012-10-03 | 株式会社東芝 | 検査項目選定装置、検査項目選定方法、及び検査項目選定プログラム |
| RU2473555C2 (ru) * | 2006-12-19 | 2013-01-27 | ДжинГоу, Инк. | Новые способы функционального анализа большого количества экспериментальных данных и групп генов, идентифицированных из указанных данных |
| FI20070159A0 (fi) * | 2007-02-23 | 2007-02-23 | Teknillinen Korkeakoulu | Menetelmä informaation integrointiin, valintaan ja esityksen oppimiseen |
| US20120143805A1 (en) * | 2008-09-09 | 2012-06-07 | Somalogic, Inc. | Cancer Biomarkers and Uses Thereof |
| CA3011730C (en) * | 2008-09-09 | 2022-05-17 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| GB2463401B (en) * | 2008-11-12 | 2014-01-29 | Caris Life Sciences Luxembourg Holdings S A R L | Characterizing prostate disorders by analysis of microvesicles |
| EP2239675A1 (en) * | 2009-04-07 | 2010-10-13 | BIOCRATES Life Sciences AG | Method for in vitro diagnosing a complex disease |
| CN101901345B (zh) * | 2009-05-27 | 2013-02-27 | 复旦大学 | 一种差异蛋白质组学的分类方法 |
| JP2013515270A (ja) * | 2009-12-22 | 2013-05-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 前立腺癌の代謝学的プロファイリング |
| EP2354246A1 (en) * | 2010-02-05 | 2011-08-10 | febit holding GmbH | miRNA in the diagnosis of ovarian cancer |
| JP2012051822A (ja) * | 2010-08-31 | 2012-03-15 | Institute Of Physical & Chemical Research | 肺癌診断用ポリペプチド、肺癌の検出方法、および治療効果の評価方法 |
| JP5637373B2 (ja) * | 2010-09-28 | 2014-12-10 | 株式会社Ｓｃｒｅｅｎホールディングス | 画像の分類方法、外観検査方法および外観検査装置 |
| CA2830602A1 (en) * | 2011-03-22 | 2012-09-27 | Thomas J. Fahey, Iii | Distinguishing benign and malignant indeterminate thyroid lesions |
| JP5645761B2 (ja) * | 2011-06-23 | 2014-12-24 | 登史夫 小林 | 医療データ解析方法、医療データ解析装置およびプログラム |
| CN104677999A (zh) * | 2013-11-29 | 2015-06-03 | 沈阳药科大学 | 血浆用于区分肝癌与肺癌的生物标记物 |
| EP4137586A1 (en) * | 2014-08-07 | 2023-02-22 | Agency for Science, Technology and Research | Microrna biomarker for the diagnosis of gastric cancer |
| CN105243296A (zh) * | 2015-09-28 | 2016-01-13 | 丽水学院 | 联合mRNA和microRNA表达谱芯片的肿瘤特征基因选择方法 |
| CN105701365B (zh) * | 2016-01-12 | 2018-09-07 | 西安电子科技大学 | 发现癌症相关基因的方法及相关系统、药物制备方法 |
| CN105550715A (zh) * | 2016-01-22 | 2016-05-04 | 大连理工大学 | 一种基于近邻传播聚类的集成分类器构建方法 |
-
2017
- 2017-01-20 JP JP2017008789A patent/JP6280997B1/ja active Active
- 2017-10-31 JP JP2018547221A patent/JP7021097B2/ja active Active
- 2017-10-31 EP EP17865774.8A patent/EP3534281A4/en active Pending
- 2017-10-31 CN CN201780067594.XA patent/CN109923614A/zh active Pending
- 2017-10-31 RU RU2019116786A patent/RU2765695C2/ru active
- 2017-10-31 US US16/346,017 patent/US20190267113A1/en active Pending
- 2017-10-31 WO PCT/JP2017/039363 patent/WO2018079840A1/ja unknown
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2021
- 2021-11-17 JP JP2021187345A patent/JP7411619B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3534281A4 (en) | 2020-06-03 |
| RU2019116786A (ru) | 2020-11-30 |
| CN109923614A (zh) | 2019-06-21 |
| JP6280997B1 (ja) | 2018-02-14 |
| RU2765695C2 (ru) | 2022-02-02 |
| US20190267113A1 (en) | 2019-08-29 |
| JP2022024092A (ja) | 2022-02-08 |
| EP3534281A1 (en) | 2019-09-04 |
| JP7411619B2 (ja) | 2024-01-11 |
| JP7021097B2 (ja) | 2022-02-16 |
| WO2018079840A1 (ja) | 2018-05-03 |
| JPWO2018079840A1 (ja) | 2019-09-19 |
| JP2018077814A (ja) | 2018-05-17 |