RU2019108092A - Тиогидантоиновые антагонисты андрогеновых рецепторов для лечения рака - Google Patents

Тиогидантоиновые антагонисты андрогеновых рецепторов для лечения рака Download PDF

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Publication number
RU2019108092A
RU2019108092A RU2019108092A RU2019108092A RU2019108092A RU 2019108092 A RU2019108092 A RU 2019108092A RU 2019108092 A RU2019108092 A RU 2019108092A RU 2019108092 A RU2019108092 A RU 2019108092A RU 2019108092 A RU2019108092 A RU 2019108092A
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RU
Russia
Prior art keywords
thiogydantoin
antagonists
cancer treatment
androgen receptors
subject
Prior art date
Application number
RU2019108092A
Other languages
English (en)
Russian (ru)
Other versions
RU2019108092A3 (https=
Inventor
Жилль К. Биньян
Original Assignee
Янссен Фармацевтика Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Янссен Фармацевтика Нв filed Critical Янссен Фармацевтика Нв
Publication of RU2019108092A publication Critical patent/RU2019108092A/ru
Publication of RU2019108092A3 publication Critical patent/RU2019108092A3/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2019108092A 2016-08-22 2017-08-22 Тиогидантоиновые антагонисты андрогеновых рецепторов для лечения рака RU2019108092A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662377932P 2016-08-22 2016-08-22
US62/377,932 2016-08-22
PCT/IB2017/055063 WO2018037342A1 (en) 2016-08-22 2017-08-22 Thiohydantoin androgen receptor antagonists for the treatment of cancer

Publications (2)

Publication Number Publication Date
RU2019108092A true RU2019108092A (ru) 2020-09-22
RU2019108092A3 RU2019108092A3 (https=) 2020-11-30

Family

ID=60009664

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2019108092A RU2019108092A (ru) 2016-08-22 2017-08-22 Тиогидантоиновые антагонисты андрогеновых рецепторов для лечения рака

Country Status (12)

Country Link
US (1) US20190209539A1 (https=)
EP (1) EP3500259A1 (https=)
JP (1) JP2019528290A (https=)
KR (1) KR20190040030A (https=)
CN (1) CN109640986A (https=)
AU (1) AU2017316756A1 (https=)
BR (1) BR112019003406A2 (https=)
CA (1) CA3034449A1 (https=)
MA (1) MA45992A (https=)
MX (1) MX2019002097A (https=)
RU (1) RU2019108092A (https=)
WO (1) WO2018037342A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3666772A4 (en) * 2017-08-07 2021-01-20 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST
WO2020113088A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Diarylhydantoin compounds and methods of use thereof
JP7464613B2 (ja) 2019-02-01 2024-04-09 正大天晴▲藥▼▲業▼集▲団▼股▲フン▼有限公司 ジアリールチオヒダントイン化合物結晶
CN115403624B (zh) * 2022-09-30 2024-08-27 上海应用技术大学 一种二芳基硫代乙内酰脲化合物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011218173C1 (en) * 2010-02-16 2015-04-16 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and uses thereof
US9365542B2 (en) * 2012-10-26 2016-06-14 Memorial Sloan-Kettering Cancer Center Modulators of resistant androgen receptor

Also Published As

Publication number Publication date
KR20190040030A (ko) 2019-04-16
JP2019528290A (ja) 2019-10-10
WO2018037342A1 (en) 2018-03-01
MX2019002097A (es) 2019-05-15
CN109640986A (zh) 2019-04-16
RU2019108092A3 (https=) 2020-11-30
CA3034449A1 (en) 2018-03-01
MA45992A (fr) 2019-06-26
US20190209539A1 (en) 2019-07-11
AU2017316756A1 (en) 2019-02-21
EP3500259A1 (en) 2019-06-26
BR112019003406A2 (pt) 2019-05-21

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Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20211025