RU2018145520A - Стабилизация композиций бета-гидроксиизовалериановых кислот в мягких гелевых капсулах - Google Patents

Стабилизация композиций бета-гидроксиизовалериановых кислот в мягких гелевых капсулах Download PDF

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Publication number
RU2018145520A
RU2018145520A RU2018145520A RU2018145520A RU2018145520A RU 2018145520 A RU2018145520 A RU 2018145520A RU 2018145520 A RU2018145520 A RU 2018145520A RU 2018145520 A RU2018145520 A RU 2018145520A RU 2018145520 A RU2018145520 A RU 2018145520A
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RU
Russia
Prior art keywords
soft gel
gel capsule
capsule
liquid composition
weight
Prior art date
Application number
RU2018145520A
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English (en)
Russian (ru)
Other versions
RU2018145520A3 (cg-RX-API-DMAC10.html
Inventor
Мартин ПУРПУРА
Ральф ЕГЕР
Цзе Гу
Сюн ЧЖЭН
Яохуа ЧЖАН
Линвэй ДАЙ
Original Assignee
ТиЭсАй ГРУП ЛТД.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ТиЭсАй ГРУП ЛТД. filed Critical ТиЭсАй ГРУП ЛТД.
Publication of RU2018145520A publication Critical patent/RU2018145520A/ru
Publication of RU2018145520A3 publication Critical patent/RU2018145520A3/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
RU2018145520A 2016-05-25 2017-05-25 Стабилизация композиций бета-гидроксиизовалериановых кислот в мягких гелевых капсулах RU2018145520A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662341464P 2016-05-25 2016-05-25
US62/341,464 2016-05-25
PCT/US2017/034551 WO2017205673A1 (en) 2016-05-25 2017-05-25 Stabilization of beta-hydroxyisovaleric acid formulations in soft gel capsules

Publications (2)

Publication Number Publication Date
RU2018145520A true RU2018145520A (ru) 2020-06-25
RU2018145520A3 RU2018145520A3 (cg-RX-API-DMAC10.html) 2020-08-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018145520A RU2018145520A (ru) 2016-05-25 2017-05-25 Стабилизация композиций бета-гидроксиизовалериановых кислот в мягких гелевых капсулах

Country Status (12)

Country Link
US (3) US10959957B2 (cg-RX-API-DMAC10.html)
EP (1) EP3463327B1 (cg-RX-API-DMAC10.html)
JP (1) JP6929939B2 (cg-RX-API-DMAC10.html)
KR (1) KR102384266B1 (cg-RX-API-DMAC10.html)
CN (2) CN121177244A (cg-RX-API-DMAC10.html)
AU (1) AU2017270219B2 (cg-RX-API-DMAC10.html)
CA (1) CA3024584A1 (cg-RX-API-DMAC10.html)
CO (1) CO2018014085A2 (cg-RX-API-DMAC10.html)
MX (1) MX2018014407A (cg-RX-API-DMAC10.html)
MY (1) MY199597A (cg-RX-API-DMAC10.html)
RU (1) RU2018145520A (cg-RX-API-DMAC10.html)
WO (1) WO2017205673A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111888325A (zh) * 2020-08-04 2020-11-06 瑞希(重庆)生物科技有限公司 一种卡拉胶凝胶、药物赋形剂和皮肤外用制剂
JP7750505B2 (ja) * 2021-10-14 2025-10-07 中日本カプセル 株式会社 カプセル及びカプセルの製造方法

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* Cited by examiner, † Cited by third party
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US2870062A (en) * 1956-04-27 1959-01-20 Scherer Corp R P Gelatin composition for capsules
US5200191A (en) 1991-09-11 1993-04-06 Banner Gelatin Products Corp. Softgel manufacturing process
US5569466A (en) 1995-05-17 1996-10-29 R. P. Scherer Corporation Fill compositions for soft elastic gel capsules
US6340473B1 (en) 1999-07-07 2002-01-22 R.P. Scherer Technologies, Inc. Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same
DE10064312C2 (de) 2000-12-22 2003-05-22 Degussa Cholinpyruvat-Hydrat, Verfahren zu dessen Herstellung, Cholinpyruvat-Hydrat enthaltende Formulierung sowie deren Verwendung
US7740878B2 (en) * 2001-10-22 2010-06-22 Danisco A/S Use of betaine to enhance exercise performance
ATE374602T1 (de) 2001-12-21 2007-10-15 Supernus Pharmaceuticals Inc Orale kapselformulierung mit verbesserter physikalischer stabilität
DE10208568A1 (de) 2002-02-27 2003-09-18 Degussa Bioactives Deutschland Verbindung, enthaltend Kreatin, eine Säure-Komponente und/oder einen Komplex-Bildner
DE10217557A1 (de) 2002-04-19 2003-11-06 Degussa Bioactives Gmbh Funktionsnahrungsmittel enthaltend eine Phospholipid-haltige stabile Matrix
US20050215640A1 (en) 2004-03-26 2005-09-29 Baxter Jeffrey H HMB compositions and uses thereof
US8231896B2 (en) * 2004-11-08 2012-07-31 R.P. Scherer Technologies, Llc Non-gelatin soft capsule system
DE102004060914A1 (de) 2004-12-17 2006-07-06 Bioghurt Biogarde Gmbh & Co. Kg Verwendung von Liponsäure-haltigen Cyclodextrin-Komplexen
EP2242489A1 (en) * 2005-02-15 2010-10-27 Jallal Messadek Combination therapeutic compositions and method of use
DE102005061765A1 (de) 2005-05-19 2006-11-23 Degussa FreshTech Beverages LLC, Milwaukee Füllmaterial für einen Getränkebehälter
CN101574146B (zh) * 2008-05-07 2012-06-13 北京康比特体育科技股份有限公司 一种含有hmb的运动营养补剂
JP2009153529A (ja) * 2009-04-17 2009-07-16 Tsujido Chemical Corp 食品組成物
ES2608483T3 (es) * 2009-12-18 2017-04-11 Metabolic Technologies, Inc. Método mejorado de administración de beta-hidroxi-beta-metilbutirato (HMB)
CN103338658A (zh) 2010-12-22 2013-10-02 雅培制药有限公司 含有β-羟基-β甲基丁酸钙和共轭亚油酸的营养型产品
MX2014000419A (es) * 2011-07-15 2014-09-22 Nusirt Sciences Inc Composicones y metodos para modular trayectorias metabolicas.
BR112015005199B1 (pt) 2012-09-10 2022-09-06 Metabolic Technologies, Inc Composição, e, método para fornecer um benefício a um animal em necessidade do mesmo
BR112015010947A2 (en) 2012-11-13 2018-06-05 Nusirt Sciences, Inc. compositions and methods for increasing energy metabolism.
US20140272000A1 (en) 2013-03-14 2014-09-18 Metabolic Technologies, Inc. Liquids and Foodstuffs Containing beta-hydroxy-beta-methylbutyrate (HMB) in the Free Acid Form and Methods of Manufacturing or Producing the Same
JP6389237B2 (ja) * 2013-03-15 2018-09-12 パセオン ソフトジェルズ インコーポレイティド 非ゼラチン性腸溶性軟質カプセル
HK1221609A1 (zh) 2013-05-01 2017-06-09 Abbott Laboratories 增强老化肌肉再生的方法
EP3082778B1 (en) * 2013-12-18 2019-04-03 Capsugel Belgium NV Stable liquid filled hard capsule comprising beta-hydroxy-beta-methylbutyric acid
WO2015195990A1 (en) * 2014-06-20 2015-12-23 Banner Life Sciences Llc Liquid-filled immediate release soft gelatin capsules
JP2018090504A (ja) * 2016-11-30 2018-06-14 株式会社東洋新薬 筋肉増強用組成物

Also Published As

Publication number Publication date
EP3463327B1 (en) 2024-04-17
JP2019517576A (ja) 2019-06-24
JP6929939B2 (ja) 2021-09-01
EP3463327A1 (en) 2019-04-10
US12133920B2 (en) 2024-11-05
MX2018014407A (es) 2019-02-21
KR102384266B1 (ko) 2022-04-06
EP3463327A4 (en) 2020-01-22
AU2017270219A1 (en) 2018-11-29
AU2017270219B2 (en) 2023-03-16
US20170340572A1 (en) 2017-11-30
BR112018073949A2 (pt) 2019-02-26
EP3463327C0 (en) 2024-04-17
RU2018145520A3 (cg-RX-API-DMAC10.html) 2020-08-26
CA3024584A1 (en) 2017-11-30
US10959957B2 (en) 2021-03-30
US20250057773A1 (en) 2025-02-20
BR112018073949A8 (pt) 2023-03-21
US20210212953A1 (en) 2021-07-15
MY199597A (en) 2023-11-08
WO2017205673A1 (en) 2017-11-30
KR20190021259A (ko) 2019-03-05
CO2018014085A2 (es) 2019-03-18
CN121177244A (zh) 2025-12-23
CN109562087A (zh) 2019-04-02

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Legal Events

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FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20210125