RU2018107840A3 - - Google Patents

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Publication number
RU2018107840A3
RU2018107840A3 RU2018107840A RU2018107840A RU2018107840A3 RU 2018107840 A3 RU2018107840 A3 RU 2018107840A3 RU 2018107840 A RU2018107840 A RU 2018107840A RU 2018107840 A RU2018107840 A RU 2018107840A RU 2018107840 A3 RU2018107840 A3 RU 2018107840A3
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RU
Russia
Application number
RU2018107840A
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Russian (ru)
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RU2737430C2 (ru
RU2018107840A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of RU2018107840A publication Critical patent/RU2018107840A/ru
Publication of RU2018107840A3 publication Critical patent/RU2018107840A3/ru
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Publication of RU2737430C2 publication Critical patent/RU2737430C2/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/02Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of guanidine from cyanamide, calcium cyanamide or dicyandiamides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/06Purification or separation of guanidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2018107840A 2015-08-11 2016-08-10 Способ получения соединения n-(3,5-диметилфенил)-n'-(2-трифторметилфенил)гуанидина RU2737430C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15382424 2015-08-11
EP15382424.8 2015-08-11
ARP150102582A AR101498A1 (es) 2015-08-11 2015-08-11 Procedimiento para la preparación del compuesto n-(3,5-dimetilfenil)-n-(2-trifluorometilfenil)guanidina y su forma cristalina a
AR20150102582 2015-08-11
PCT/EP2016/069033 WO2017025560A1 (en) 2015-08-11 2016-08-10 A process for the preparation of the compound n-(3,5-dimethylphenyl)-n'-(2-trifluoromethylphenyl) guanidine

Publications (3)

Publication Number Publication Date
RU2018107840A RU2018107840A (ru) 2019-09-12
RU2018107840A3 true RU2018107840A3 (US08063081-20111122-C00044.png) 2019-12-18
RU2737430C2 RU2737430C2 (ru) 2020-11-30

Family

ID=56799434

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018107840A RU2737430C2 (ru) 2015-08-11 2016-08-10 Способ получения соединения n-(3,5-диметилфенил)-n'-(2-трифторметилфенил)гуанидина

Country Status (21)

Country Link
US (1) US10343984B2 (US08063081-20111122-C00044.png)
EP (1) EP3334707B1 (US08063081-20111122-C00044.png)
JP (1) JP6748188B2 (US08063081-20111122-C00044.png)
CN (1) CN107922322B (US08063081-20111122-C00044.png)
AR (1) AR101498A1 (US08063081-20111122-C00044.png)
BR (1) BR112018002614B1 (US08063081-20111122-C00044.png)
CA (1) CA2994781A1 (US08063081-20111122-C00044.png)
CY (1) CY1122481T1 (US08063081-20111122-C00044.png)
DK (1) DK3334707T3 (US08063081-20111122-C00044.png)
ES (1) ES2756580T3 (US08063081-20111122-C00044.png)
HK (1) HK1256253A1 (US08063081-20111122-C00044.png)
HR (1) HRP20192301T1 (US08063081-20111122-C00044.png)
HU (1) HUE046959T2 (US08063081-20111122-C00044.png)
LT (1) LT3334707T (US08063081-20111122-C00044.png)
MX (1) MX2018001548A (US08063081-20111122-C00044.png)
PL (1) PL3334707T3 (US08063081-20111122-C00044.png)
PT (1) PT3334707T (US08063081-20111122-C00044.png)
RS (1) RS59759B1 (US08063081-20111122-C00044.png)
RU (1) RU2737430C2 (US08063081-20111122-C00044.png)
SI (1) SI3334707T1 (US08063081-20111122-C00044.png)
WO (1) WO2017025560A1 (US08063081-20111122-C00044.png)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN172842B (US08063081-20111122-C00044.png) * 1990-05-17 1993-12-11 Boots Pharmaceuticals Limited
AU2962297A (en) * 1996-05-24 1998-01-05 Neurosearch A/S Phenyl derivatives useful as blockers of chloride channels
US8283370B2 (en) * 2008-10-03 2012-10-09 The United States Of America As Represented By The Secretary Of The Army Imidazolidinedione derivatives as antimalarial agents, preparation thereof, and methods of use
BR112014008589B1 (pt) * 2011-10-11 2022-06-14 Universidad Nacional De Quilmes Compostos derivados de fenil-guanidina, processo para a preparação destes, uso dos mesmos e composição farmacêutica

Also Published As

Publication number Publication date
SI3334707T1 (sl) 2020-03-31
JP2018525393A (ja) 2018-09-06
CA2994781A1 (en) 2017-02-16
EP3334707A1 (en) 2018-06-20
CN107922322A (zh) 2018-04-17
AR101498A1 (es) 2016-12-21
PL3334707T3 (pl) 2020-05-18
PT3334707T (pt) 2020-01-14
US10343984B2 (en) 2019-07-09
CN107922322B (zh) 2023-11-03
LT3334707T (lt) 2020-01-27
HRP20192301T1 (hr) 2020-03-20
RU2737430C2 (ru) 2020-11-30
RU2018107840A (ru) 2019-09-12
US20180244608A1 (en) 2018-08-30
MX2018001548A (es) 2018-06-22
HUE046959T2 (hu) 2020-04-28
WO2017025560A1 (en) 2017-02-16
EP3334707B1 (en) 2019-10-09
ES2756580T3 (es) 2020-04-27
BR112018002614B1 (pt) 2023-04-11
HK1256253A1 (zh) 2019-09-20
JP6748188B2 (ja) 2020-08-26
DK3334707T3 (da) 2020-01-06
BR112018002614A2 (US08063081-20111122-C00044.png) 2018-10-02
CY1122481T1 (el) 2021-01-27
RS59759B1 (sr) 2020-02-28

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