PL3334707T3 - Sposób wytwarzania związku stanowiącego n-(3,5-dimetylofenylo)-n'-(2-trifluorometylofenylo)guanidynę - Google Patents
Sposób wytwarzania związku stanowiącego n-(3,5-dimetylofenylo)-n'-(2-trifluorometylofenylo)guanidynęInfo
- Publication number
- PL3334707T3 PL3334707T3 PL16756641T PL16756641T PL3334707T3 PL 3334707 T3 PL3334707 T3 PL 3334707T3 PL 16756641 T PL16756641 T PL 16756641T PL 16756641 T PL16756641 T PL 16756641T PL 3334707 T3 PL3334707 T3 PL 3334707T3
- Authority
- PL
- Poland
- Prior art keywords
- trifluoromethylphenyl
- dimethylphenyl
- guanidine
- compound
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/02—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of guanidine from cyanamide, calcium cyanamide or dicyandiamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/06—Purification or separation of guanidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP150102582A AR101498A1 (es) | 2015-08-11 | 2015-08-11 | Procedimiento para la preparación del compuesto n-(3,5-dimetilfenil)-n-(2-trifluorometilfenil)guanidina y su forma cristalina a |
EP15382424 | 2015-08-11 | ||
PCT/EP2016/069033 WO2017025560A1 (en) | 2015-08-11 | 2016-08-10 | A process for the preparation of the compound n-(3,5-dimethylphenyl)-n'-(2-trifluoromethylphenyl) guanidine |
EP16756641.3A EP3334707B1 (en) | 2015-08-11 | 2016-08-10 | A process for the preparation of the compound n-(3,5-dimethylphenyl)-n'-(2-trifluoromethylphenyl) guanidine |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3334707T3 true PL3334707T3 (pl) | 2020-05-18 |
Family
ID=56799434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL16756641T PL3334707T3 (pl) | 2015-08-11 | 2016-08-10 | Sposób wytwarzania związku stanowiącego n-(3,5-dimetylofenylo)-n'-(2-trifluorometylofenylo)guanidynę |
Country Status (21)
Country | Link |
---|---|
US (1) | US10343984B2 (pl) |
EP (1) | EP3334707B1 (pl) |
JP (1) | JP6748188B2 (pl) |
CN (1) | CN107922322B (pl) |
AR (1) | AR101498A1 (pl) |
BR (1) | BR112018002614B1 (pl) |
CA (1) | CA2994781A1 (pl) |
CY (1) | CY1122481T1 (pl) |
DK (1) | DK3334707T3 (pl) |
ES (1) | ES2756580T3 (pl) |
HK (1) | HK1256253A1 (pl) |
HR (1) | HRP20192301T1 (pl) |
HU (1) | HUE046959T2 (pl) |
LT (1) | LT3334707T (pl) |
MX (1) | MX2018001548A (pl) |
PL (1) | PL3334707T3 (pl) |
PT (1) | PT3334707T (pl) |
RS (1) | RS59759B1 (pl) |
RU (1) | RU2737430C2 (pl) |
SI (1) | SI3334707T1 (pl) |
WO (1) | WO2017025560A1 (pl) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN172842B (pl) * | 1990-05-17 | 1993-12-11 | Boots Pharmaceuticals Limited | |
AU2962297A (en) * | 1996-05-24 | 1998-01-05 | Neurosearch A/S | Phenyl derivatives useful as blockers of chloride channels |
US8283370B2 (en) * | 2008-10-03 | 2012-10-09 | The United States Of America As Represented By The Secretary Of The Army | Imidazolidinedione derivatives as antimalarial agents, preparation thereof, and methods of use |
DK2766342T3 (en) * | 2011-10-11 | 2016-05-02 | Univ Nac Quilmes | PHENYL-guanidine derivatives |
-
2015
- 2015-08-11 AR ARP150102582A patent/AR101498A1/es unknown
-
2016
- 2016-08-10 LT LTEP16756641.3T patent/LT3334707T/lt unknown
- 2016-08-10 SI SI201630561T patent/SI3334707T1/sl unknown
- 2016-08-10 MX MX2018001548A patent/MX2018001548A/es unknown
- 2016-08-10 PT PT167566413T patent/PT3334707T/pt unknown
- 2016-08-10 DK DK16756641.3T patent/DK3334707T3/da active
- 2016-08-10 US US15/751,437 patent/US10343984B2/en active Active
- 2016-08-10 HU HUE16756641A patent/HUE046959T2/hu unknown
- 2016-08-10 ES ES16756641T patent/ES2756580T3/es active Active
- 2016-08-10 RU RU2018107840A patent/RU2737430C2/ru active
- 2016-08-10 CA CA2994781A patent/CA2994781A1/en active Pending
- 2016-08-10 BR BR112018002614-0A patent/BR112018002614B1/pt active IP Right Grant
- 2016-08-10 EP EP16756641.3A patent/EP3334707B1/en active Active
- 2016-08-10 JP JP2018506997A patent/JP6748188B2/ja active Active
- 2016-08-10 PL PL16756641T patent/PL3334707T3/pl unknown
- 2016-08-10 RS RS20191669A patent/RS59759B1/sr unknown
- 2016-08-10 WO PCT/EP2016/069033 patent/WO2017025560A1/en active Application Filing
- 2016-08-10 CN CN201680045772.4A patent/CN107922322B/zh active Active
-
2018
- 2018-11-29 HK HK18115310.1A patent/HK1256253A1/zh unknown
-
2019
- 2019-12-20 HR HRP20192301TT patent/HRP20192301T1/hr unknown
- 2019-12-27 CY CY20191101359T patent/CY1122481T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN107922322A (zh) | 2018-04-17 |
JP6748188B2 (ja) | 2020-08-26 |
RU2018107840A (ru) | 2019-09-12 |
DK3334707T3 (da) | 2020-01-06 |
US20180244608A1 (en) | 2018-08-30 |
CA2994781A1 (en) | 2017-02-16 |
AR101498A1 (es) | 2016-12-21 |
HRP20192301T1 (hr) | 2020-03-20 |
JP2018525393A (ja) | 2018-09-06 |
PT3334707T (pt) | 2020-01-14 |
EP3334707B1 (en) | 2019-10-09 |
LT3334707T (lt) | 2020-01-27 |
RU2018107840A3 (pl) | 2019-12-18 |
CY1122481T1 (el) | 2021-01-27 |
SI3334707T1 (sl) | 2020-03-31 |
HK1256253A1 (zh) | 2019-09-20 |
CN107922322B (zh) | 2023-11-03 |
US10343984B2 (en) | 2019-07-09 |
BR112018002614A2 (pl) | 2018-10-02 |
RS59759B1 (sr) | 2020-02-28 |
WO2017025560A1 (en) | 2017-02-16 |
HUE046959T2 (hu) | 2020-04-28 |
RU2737430C2 (ru) | 2020-11-30 |
ES2756580T3 (es) | 2020-04-27 |
BR112018002614B1 (pt) | 2023-04-11 |
EP3334707A1 (en) | 2018-06-20 |
MX2018001548A (es) | 2018-06-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL266611A (en) | Converted N-(3-fluorophenyl)-pyrrolidine substances, process for their preparation and medical use thereof | |
HK1251546A1 (zh) | S-氯胺酮的(s)-csa鹽、s-氯胺酮的(r)-csa鹽和用於製備s-氯胺酮的方法 | |
SI3097098T1 (sl) | Postopek za pripravo N-((3-aminooksetana-3-il)metil)-2-(1,1-diokso- 3,5-dihidro-1,4-benzotiazepin-4-il)-6-metil-kinazolin-4-amina | |
CR20170315A (es) | Inhibridores bace 1 selectivos | |
IL267899A (en) | 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives as magl inhibitors | |
DK3497081T3 (da) | Fremgangsmåde til fremstilling af 4-ammonium-2,2,6,6-tetraalkylpiperidinylsalte | |
AP2016009387A0 (en) | Agrochemical composition comprising a n, n'-disubstituted (thio)urea for the improvement of crop productivity | |
MY183123A (en) | Synthesis of copanlisib and its di hydrochloride salt | |
IL260665B (en) | Improved process for the preparation of osimertinib (azd9291) or its salt and "azd9291 aniline" or its salt | |
PL3317272T3 (pl) | Chwastobójczo skuteczne pochodne N-(1,3,4-oksadiazol-2-ilo)arylokarboksyamidowe | |
ZA201907272B (en) | N-(4-pyridyl)nicotinamide compound or salt thereof | |
DK3456712T3 (da) | Hidtil ukendte 2,4,6-trisubstitueret S-triazinforbindelse, fremgangsmåde til fremstilling deraf og anvendelse deraf | |
ZA202004349B (en) | Fluoralkenyl compounds, process for preparation and use thereof | |
HK1256253A1 (zh) | 化合物n-(3,5-二甲基苯基)-n'-(2-三氟甲基苯基)胍的製備方法 | |
EP3294703A4 (en) | A process for the preparation of verapamil hydrochloride | |
PL3274339T3 (pl) | Sposób wytwarzania chlorowodorków 2- (homo)-piperazyno-1,3-benzotiazyn-4-onu | |
PT3564230T (pt) | Compostos de guanidina substituídos | |
DK3330271T3 (da) | PYRROLO[2,3-d]PYRIMIDINFORBINDELSE ELLER SALT DERAF | |
GB201704384D0 (en) | N-((3,4,5-Trimethoxystyryl)aryl) cinnamamide compounds as potential anticancer agents and process for the preparation thereof | |
EP3414225C0 (en) | CRYSTALLINE MODIFICATIONS OF N-(4,5-BISMETHANESULFONYL-2-METHYLBENZOYL)-GUANIDINE HYDROCHLORIDE AND N-(4,5-BISMETHANESULFONYL-2-METHYLBENZOYL)-GUANIDINE SALTS | |
ES2722574R1 (es) | Proceso para la preparación de 9beta,10alfa-progesterona (retroprogesterona) | |
PL3153022T3 (pl) | N-(3’,4’-dichloro-5-metoksybifenyl-2-ylo)-3-(difluorometylo)-1-metylo-1H-pirazolo-4-karboksyamid | |
GB201523219D0 (en) | Piperidine-carboxylic acid amide pharmaceutical intermediate N- (2,6- dimethylphenoxy) - 4-pyridinecarboxamide synthesis method | |
UA106614U (uk) | N-(фенілгідразидоацетил)-n'-cукцинамідоантраніламід, який виявляє протисудомну активність | |
UA94667U (uk) | Заміщені [2-(3-r-1h-[1,2,4]триазол-5-іл)феніл]аміни, що проявляють гіпоглікемічну активність |