RU2017137366A3 - - Google Patents

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Publication number
RU2017137366A3
RU2017137366A3 RU2017137366A RU2017137366A RU2017137366A3 RU 2017137366 A3 RU2017137366 A3 RU 2017137366A3 RU 2017137366 A RU2017137366 A RU 2017137366A RU 2017137366 A RU2017137366 A RU 2017137366A RU 2017137366 A3 RU2017137366 A3 RU 2017137366A3
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RU
Russia
Application number
RU2017137366A
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RU2017137366A (ru
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Publication date
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Publication of RU2017137366A publication Critical patent/RU2017137366A/ru
Publication of RU2017137366A3 publication Critical patent/RU2017137366A3/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
RU2017137366A 2015-03-26 2016-03-25 Конденсированные бициклические соединения для лечения заболевания RU2017137366A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562138725P 2015-03-26 2015-03-26
US62/138,725 2015-03-26
PCT/IB2016/000606 WO2016151403A1 (en) 2015-03-26 2016-03-25 Fused bicyclic compounds for the treatment of disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2021107054A Division RU2021107054A (ru) 2015-03-26 2016-03-25 Конденсированные бициклические соединения для лечения заболевания

Publications (2)

Publication Number Publication Date
RU2017137366A RU2017137366A (ru) 2019-04-26
RU2017137366A3 true RU2017137366A3 (ru) 2019-07-17

Family

ID=56072361

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2021107054A RU2021107054A (ru) 2015-03-26 2016-03-25 Конденсированные бициклические соединения для лечения заболевания
RU2017137366A RU2017137366A (ru) 2015-03-26 2016-03-25 Конденсированные бициклические соединения для лечения заболевания

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU2021107054A RU2021107054A (ru) 2015-03-26 2016-03-25 Конденсированные бициклические соединения для лечения заболевания

Country Status (16)

Country Link
US (4) US10421759B2 (ru)
EP (2) EP3274350A1 (ru)
JP (1) JP6843061B2 (ru)
KR (1) KR20180003545A (ru)
CN (1) CN107912042A (ru)
AU (2) AU2016238523A1 (ru)
BR (1) BR112017020374A2 (ru)
CA (1) CA2980394A1 (ru)
CL (1) CL2017002405A1 (ru)
CO (1) CO2017010621A2 (ru)
HK (1) HK1249756A1 (ru)
IL (1) IL254572A0 (ru)
MX (1) MX370897B (ru)
RU (2) RU2021107054A (ru)
SG (2) SG11201707610PA (ru)
WO (1) WO2016151403A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3274350A1 (en) * 2015-03-26 2018-01-31 Akarna Therapeutics, Ltd. Fused bicyclic compounds for the treatment of disease
WO2017205684A1 (en) * 2016-05-25 2017-11-30 Akarna Therapeutics, Ltd. Combination therapies with farnesoid x receptor (fxr) modulators
CN109789149A (zh) * 2016-05-25 2019-05-21 阿卡纳治疗学有限公司 用于治疗疾病的稠合双环化合物
RU2019144064A (ru) * 2017-06-02 2021-07-13 Акарна Терапьютикс, Лтд. Конденсированные бициклические соединения
CN108264474B (zh) * 2018-02-09 2019-10-25 浙江师范大学 一种色胺及其衍生物的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595311B2 (en) * 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
JP4679517B2 (ja) * 2003-07-23 2011-04-27 エグゼリクシス, インコーポレイテッド 薬剤としてのアゼピン誘導体
WO2006020680A2 (en) 2004-08-10 2006-02-23 Exelixis, Inc. Heterocyclic compounds as pharmaceutical agents
WO2006109633A1 (ja) 2005-04-07 2006-10-19 Daiichi Sankyo Company, Limited 置換インドール化合物
CA2633243C (en) * 2005-12-15 2014-05-27 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents
US7998995B2 (en) 2006-12-08 2011-08-16 Exelixis Patent Company Llc LXR and FXR modulators
US20090131409A1 (en) 2007-10-22 2009-05-21 Wyeth 1,4,5,6,7,8-HEXAHYDRO -PYRROLO[2,3-d]AZEPINES AND -IMIDAZO[4,5-d]AZEPINES AS MODULATORS OF NUCLEAR RECEPTOR ACTIVITY
US20090137554A1 (en) * 2007-10-22 2009-05-28 Wyeth 1,4,5,6-TETRAHYDRO -PYRROLO[2,3-d]AZEPINES AND -IMIDAZO[4,5-d]AZEPINES AS MODULATORS OF NUCLEAR RECEPTOR ACTIVITY
WO2010036362A1 (en) 2008-09-26 2010-04-01 Wyeth 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate nuclear receptor inhibitors
MX370480B (es) * 2014-11-21 2019-12-16 Akarna Therapeutics Ltd Compuestos bicíclicos fusionados para el tratamiento de enfermedades.
CA2971755A1 (en) * 2014-12-22 2016-06-30 Akarna Therapeutics, Ltd. Fused bicyclic compounds for the treatment of disease
EP3274350A1 (en) * 2015-03-26 2018-01-31 Akarna Therapeutics, Ltd. Fused bicyclic compounds for the treatment of disease

Also Published As

Publication number Publication date
US20210214362A1 (en) 2021-07-15
SG10201908881PA (en) 2019-11-28
JP6843061B2 (ja) 2021-03-17
CA2980394A1 (en) 2016-09-29
BR112017020374A2 (pt) 2018-06-05
MX370897B (es) 2020-01-09
CN107912042A (zh) 2018-04-13
EP3274350A1 (en) 2018-01-31
CL2017002405A1 (es) 2018-04-27
SG11201707610PA (en) 2017-10-30
KR20180003545A (ko) 2018-01-09
EP3715348A1 (en) 2020-09-30
WO2016151403A1 (en) 2016-09-29
AU2020256301A1 (en) 2020-11-05
RU2021107054A (ru) 2021-03-31
US20230002394A1 (en) 2023-01-05
HK1249756A1 (zh) 2018-11-09
JP2018510876A (ja) 2018-04-19
RU2017137366A (ru) 2019-04-26
US10421759B2 (en) 2019-09-24
MX2017012342A (es) 2018-06-11
AU2016238523A1 (en) 2017-11-09
US20180118752A1 (en) 2018-05-03
IL254572A0 (en) 2017-11-30
US20200079782A1 (en) 2020-03-12
CO2017010621A2 (es) 2018-01-31

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