RU2016123361A - Композиции, включающие клетки плацентарного перфузата человека - Google Patents
Композиции, включающие клетки плацентарного перфузата человека Download PDFInfo
- Publication number
- RU2016123361A RU2016123361A RU2016123361A RU2016123361A RU2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A
- Authority
- RU
- Russia
- Prior art keywords
- cells
- composition
- composition according
- subject
- perfusion solution
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 102
- 230000003169 placental effect Effects 0.000 title claims 32
- 210000004027 cell Anatomy 0.000 claims 52
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 39
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 39
- 230000010412 perfusion Effects 0.000 claims 22
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 8
- 101100220044 Homo sapiens CD34 gene Proteins 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 6
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 claims 5
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 claims 5
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 claims 5
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 claims 5
- 101001057504 Homo sapiens Interferon-stimulated gene 20 kDa protein Proteins 0.000 claims 5
- 101001055144 Homo sapiens Interleukin-2 receptor subunit alpha Proteins 0.000 claims 5
- 101001126417 Homo sapiens Platelet-derived growth factor receptor alpha Proteins 0.000 claims 5
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 5
- 102100027268 Interferon-stimulated gene 20 kDa protein Human genes 0.000 claims 5
- 102000008730 Nestin Human genes 0.000 claims 5
- 108010088225 Nestin Proteins 0.000 claims 5
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 5
- 102100030485 Platelet-derived growth factor receptor alpha Human genes 0.000 claims 5
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 5
- 210000005055 nestin Anatomy 0.000 claims 5
- 208000009329 Graft vs Host Disease Diseases 0.000 claims 4
- 210000003169 central nervous system Anatomy 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 208000024908 graft versus host disease Diseases 0.000 claims 4
- 206010068051 Chimerism Diseases 0.000 claims 2
- 206010070511 Hypoxic-ischaemic encephalopathy Diseases 0.000 claims 2
- 208000037212 Neonatal hypoxic and ischemic brain injury Diseases 0.000 claims 2
- 208000009973 brain hypoxia - ischemia Diseases 0.000 claims 2
- 208000014951 hematologic disease Diseases 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 230000003211 malignant effect Effects 0.000 claims 2
- 208000030159 metabolic disease Diseases 0.000 claims 2
- 208000033300 perinatal asphyxia Diseases 0.000 claims 2
- 208000001076 sarcopenia Diseases 0.000 claims 2
- 208000019838 Blood disease Diseases 0.000 claims 1
- 210000002826 placenta Anatomy 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361905076P | 2013-11-15 | 2013-11-15 | |
| US201361905077P | 2013-11-15 | 2013-11-15 | |
| US61/905,076 | 2013-11-15 | ||
| US61/905,077 | 2013-11-15 | ||
| PCT/US2014/065665 WO2015073800A2 (en) | 2013-11-15 | 2014-11-14 | Compositions comprising human placental perfusate cells, subpopulations thereof, and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2016123361A true RU2016123361A (ru) | 2017-12-20 |
Family
ID=53058264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016123361A RU2016123361A (ru) | 2013-11-15 | 2014-11-14 | Композиции, включающие клетки плацентарного перфузата человека |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160279171A1 (https=) |
| EP (1) | EP3068432A4 (https=) |
| JP (4) | JP2016537362A (https=) |
| KR (3) | KR20160098244A (https=) |
| CN (2) | CN105916521A (https=) |
| AU (3) | AU2014348454A1 (https=) |
| CA (1) | CA2930573C (https=) |
| MX (2) | MX2016006270A (https=) |
| RU (1) | RU2016123361A (https=) |
| WO (1) | WO2015073800A2 (https=) |
| ZA (1) | ZA201603270B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11707491B2 (en) * | 2016-11-11 | 2023-07-25 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods of treating neurodegenerative disorders |
| EP3595683A1 (en) * | 2017-03-15 | 2020-01-22 | Orca Biosystems, Inc. | Compositions and methods for hematopoietic stem cell transplants |
| JP2022513164A (ja) * | 2018-11-30 | 2022-02-07 | セルラリティ インク． | 胎盤由来同種ｃａｒ－ｔ細胞およびその使用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10001172A1 (de) | 2000-01-13 | 2001-07-26 | Max Planck Gesellschaft | Templatieren von Feststoffpartikeln mit Polymermultischichten |
| US20080152629A1 (en) * | 2000-12-06 | 2008-06-26 | James Edinger | Placental stem cell populations |
| EP2305795B1 (en) | 2000-12-06 | 2019-07-03 | Celularity, Inc. | Method of collecting placental stem cells |
| US7311905B2 (en) * | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
| ES2432493T3 (es) * | 2001-02-14 | 2013-12-03 | Anthrogenesis Corporation | Placenta de mamífero post-parto, su uso y células madre de la misma |
| EP2316918B1 (en) * | 2001-02-14 | 2015-07-01 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US7498171B2 (en) * | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| AU2005228442A1 (en) * | 2004-03-29 | 2005-10-13 | Cytomatrix, Llc | Methods for production of regulatory T cells and uses thereof |
| NZ597304A (en) * | 2005-10-13 | 2013-06-28 | Anthrogenesis Corp | Immunomodulation using placental stem cells |
| WO2007087292A2 (en) * | 2006-01-23 | 2007-08-02 | Athersys, Inc. | Mapc treatment of brain injuries and diseases |
| EP1976978A2 (en) * | 2005-12-29 | 2008-10-08 | Anthrogenesis Corporation | Co-culture of placental stem cells and stem cells from a second source |
| PL2471907T3 (pl) | 2005-12-29 | 2019-07-31 | Celularity, Inc. | Populacje komórek macierzystych łożyska |
| EP4094578A1 (en) * | 2006-05-11 | 2022-11-30 | Celularity Inc. | Methods for collecting and using placenta cord blood stem cells |
| US8562972B2 (en) | 2006-10-23 | 2013-10-22 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| CA2677679A1 (en) * | 2007-02-12 | 2008-08-21 | Anthrogenesis Corporation | Hepatocytes and chondrocytes from adherent placental stem cells; and cd34+, cd45- placental stem cell-enriched cell populations |
| CA2688504A1 (en) * | 2007-06-18 | 2008-12-24 | Children's Hospital & Research Center At Oakland | Method of isolating stem and progenitor cells from placenta |
| KR20220122774A (ko) * | 2007-09-26 | 2022-09-02 | 셀룰래리티 인코포레이티드 | 인간 태반 관류액으로부터의 혈관형성 세포 |
| RU2536242C2 (ru) * | 2007-09-28 | 2014-12-20 | Антродженезис Корпорейшн | Угнетение опухолей с помощью плацентарного перфузата человека и выделенных из плаценты человека вспомогательных натуральных клеток-киллеров |
| DK2375907T3 (da) * | 2008-11-21 | 2019-06-11 | Celularity Inc | Behandling af sygdomme, lidelser eller tilstande i lungerne under anvendelse af placentaceller |
| EP2405912A2 (en) * | 2009-03-12 | 2012-01-18 | University Of South Florida | Method of disease-induced and receptor-mediated stem cell neuroprotection |
| WO2010141654A1 (en) * | 2009-06-05 | 2010-12-09 | Anthrogenesis Corporation | Improved method of collecting placental cells |
| US20120177618A1 (en) * | 2009-07-14 | 2012-07-12 | Massachusetts Institute Of Technology | Hematopoietic stromal progenitor cells and uses thereof |
| US20110280849A1 (en) | 2010-03-26 | 2011-11-17 | Anthrogenesis Corporation | Tumor suppression using human placenta-derived intermediate natural killer cells and immunomodulatory compounds |
| DK2556145T3 (en) * | 2010-04-07 | 2016-11-07 | Anthrogenesis Corp | Angiogenesis using placental stem cells |
| MX342995B (es) * | 2010-07-13 | 2016-10-21 | Anthrogenesis Corp | Métodos de generar células asesinas naturales. |
| KR20190114045A (ko) * | 2010-12-17 | 2019-10-08 | 안트로제네시스 코포레이션 | 양막 유래 부착성 세포를 사용한, 면역-관련 질환 및 장애의 치료 |
| WO2012083023A1 (en) | 2010-12-17 | 2012-06-21 | Anthrogenesis Corporation | Treatment of spinal cord injury and traumatic brain injury using amnion derived adherent cells |
| AR084753A1 (es) * | 2010-12-30 | 2013-06-05 | Anthrogenesis Corp | Composiciones que comprenden celulas adherentes derivadas del saco amniotico (amdac) y plasma rico en plaquetas (prp) |
| WO2013055476A1 (en) | 2011-09-09 | 2013-04-18 | Anthrogenesis Corporation | Treatment of amyotrophic lateral sclerosis using placental stem cells |
| CN114134113A (zh) | 2012-08-13 | 2022-03-04 | 人类起源公司 | 自然杀伤细胞及其用途 |
| DK2909314T3 (da) | 2012-10-19 | 2021-03-08 | Celularity Inc | Behandling af smerte med amnion afledte vedhæftende celler |
-
2014
- 2014-11-14 KR KR1020167015654A patent/KR20160098244A/ko not_active Ceased
- 2014-11-14 KR KR1020217030425A patent/KR20210121277A/ko not_active Ceased
- 2014-11-14 AU AU2014348454A patent/AU2014348454A1/en not_active Abandoned
- 2014-11-14 CA CA2930573A patent/CA2930573C/en active Active
- 2014-11-14 JP JP2016530925A patent/JP2016537362A/ja active Pending
- 2014-11-14 US US15/036,649 patent/US20160279171A1/en not_active Abandoned
- 2014-11-14 CN CN201480073194.6A patent/CN105916521A/zh active Pending
- 2014-11-14 MX MX2016006270A patent/MX2016006270A/es unknown
- 2014-11-14 WO PCT/US2014/065665 patent/WO2015073800A2/en not_active Ceased
- 2014-11-14 RU RU2016123361A patent/RU2016123361A/ru unknown
- 2014-11-14 KR KR1020247005001A patent/KR20240023709A/ko not_active Ceased
- 2014-11-14 CN CN202110968902.4A patent/CN113679740A/zh active Pending
- 2014-11-14 EP EP14862931.4A patent/EP3068432A4/en not_active Withdrawn
-
2016
- 2016-05-13 MX MX2021003799A patent/MX2021003799A/es unknown
- 2016-05-13 ZA ZA2016/03270A patent/ZA201603270B/en unknown
-
2018
- 2018-11-23 US US16/199,116 patent/US20190117705A1/en not_active Abandoned
-
2019
- 2019-09-06 JP JP2019162780A patent/JP2020019777A/ja not_active Withdrawn
-
2020
- 2020-03-27 AU AU2020202182A patent/AU2020202182A1/en not_active Abandoned
-
2021
- 2021-09-24 JP JP2021155038A patent/JP2022020622A/ja not_active Withdrawn
-
2022
- 2022-08-12 AU AU2022215291A patent/AU2022215291A1/en not_active Abandoned
-
2023
- 2023-10-12 JP JP2023176697A patent/JP2024016037A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201603270B (en) | 2022-09-28 |
| KR20240023709A (ko) | 2024-02-22 |
| WO2015073800A3 (en) | 2015-07-02 |
| WO2015073800A2 (en) | 2015-05-21 |
| KR20210121277A (ko) | 2021-10-07 |
| JP2020019777A (ja) | 2020-02-06 |
| MX2016006270A (es) | 2016-09-07 |
| EP3068432A4 (en) | 2017-04-19 |
| CN105916521A (zh) | 2016-08-31 |
| MX2021003799A (es) | 2021-06-04 |
| JP2016537362A (ja) | 2016-12-01 |
| AU2022215291A1 (en) | 2022-09-01 |
| US20190117705A1 (en) | 2019-04-25 |
| CA2930573C (en) | 2023-12-05 |
| WO2015073800A8 (en) | 2015-12-17 |
| US20160279171A1 (en) | 2016-09-29 |
| AU2020202182A1 (en) | 2020-04-16 |
| CN113679740A (zh) | 2021-11-23 |
| JP2024016037A (ja) | 2024-02-06 |
| EP3068432A2 (en) | 2016-09-21 |
| AU2022215291A9 (en) | 2022-11-24 |
| AU2014348454A1 (en) | 2016-06-02 |
| CA2930573A1 (en) | 2015-05-21 |
| JP2022020622A (ja) | 2022-02-01 |
| KR20160098244A (ko) | 2016-08-18 |
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