RU2016123361A - Композиции, включающие клетки плацентарного перфузата человека - Google Patents
Композиции, включающие клетки плацентарного перфузата человека Download PDFInfo
- Publication number
- RU2016123361A RU2016123361A RU2016123361A RU2016123361A RU2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A RU 2016123361 A RU2016123361 A RU 2016123361A
- Authority
- RU
- Russia
- Prior art keywords
- cells
- composition
- composition according
- subject
- perfusion solution
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 102
- 230000003169 placental effect Effects 0.000 title claims 32
- 210000004027 cell Anatomy 0.000 claims 52
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 39
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 39
- 230000010412 perfusion Effects 0.000 claims 22
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 8
- 101100220044 Homo sapiens CD34 gene Proteins 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 6
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 claims 5
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 claims 5
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 claims 5
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 claims 5
- 101001057504 Homo sapiens Interferon-stimulated gene 20 kDa protein Proteins 0.000 claims 5
- 101001055144 Homo sapiens Interleukin-2 receptor subunit alpha Proteins 0.000 claims 5
- 101001126417 Homo sapiens Platelet-derived growth factor receptor alpha Proteins 0.000 claims 5
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 5
- 102100027268 Interferon-stimulated gene 20 kDa protein Human genes 0.000 claims 5
- 102000008730 Nestin Human genes 0.000 claims 5
- 108010088225 Nestin Proteins 0.000 claims 5
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 5
- 102100030485 Platelet-derived growth factor receptor alpha Human genes 0.000 claims 5
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 5
- 210000005055 nestin Anatomy 0.000 claims 5
- 208000009329 Graft vs Host Disease Diseases 0.000 claims 4
- 210000003169 central nervous system Anatomy 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 208000024908 graft versus host disease Diseases 0.000 claims 4
- 206010068051 Chimerism Diseases 0.000 claims 2
- 206010070511 Hypoxic-ischaemic encephalopathy Diseases 0.000 claims 2
- 208000037212 Neonatal hypoxic and ischemic brain injury Diseases 0.000 claims 2
- 208000009973 brain hypoxia - ischemia Diseases 0.000 claims 2
- 208000014951 hematologic disease Diseases 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 230000003211 malignant effect Effects 0.000 claims 2
- 208000030159 metabolic disease Diseases 0.000 claims 2
- 208000033300 perinatal asphyxia Diseases 0.000 claims 2
- 208000001076 sarcopenia Diseases 0.000 claims 2
- 208000019838 Blood disease Diseases 0.000 claims 1
- 210000002826 placenta Anatomy 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361905076P | 2013-11-15 | 2013-11-15 | |
| US201361905077P | 2013-11-15 | 2013-11-15 | |
| US61/905,076 | 2013-11-15 | ||
| US61/905,077 | 2013-11-15 | ||
| PCT/US2014/065665 WO2015073800A2 (en) | 2013-11-15 | 2014-11-14 | Compositions comprising human placental perfusate cells, subpopulations thereof, and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2016123361A true RU2016123361A (ru) | 2017-12-20 |
Family
ID=53058264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016123361A RU2016123361A (ru) | 2013-11-15 | 2014-11-14 | Композиции, включающие клетки плацентарного перфузата человека |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160279171A1 (https=) |
| EP (1) | EP3068432A4 (https=) |
| JP (4) | JP2016537362A (https=) |
| KR (3) | KR20240023709A (https=) |
| CN (2) | CN105916521A (https=) |
| AU (3) | AU2014348454A1 (https=) |
| CA (1) | CA2930573C (https=) |
| MX (2) | MX2016006270A (https=) |
| RU (1) | RU2016123361A (https=) |
| WO (1) | WO2015073800A2 (https=) |
| ZA (1) | ZA201603270B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11707491B2 (en) * | 2016-11-11 | 2023-07-25 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods of treating neurodegenerative disorders |
| EP4417210A1 (en) * | 2017-03-15 | 2024-08-21 | Orca Biosystems, Inc. | Compositions and methods for hematopoietic stem cell transplants |
| KR20210111244A (ko) * | 2018-11-30 | 2021-09-10 | 셀룰래리티 인코포레이티드 | 태반-유래 동종이계 car-t 세포 및 이의 용도 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10001172A1 (de) | 2000-01-13 | 2001-07-26 | Max Planck Gesellschaft | Templatieren von Feststoffpartikeln mit Polymermultischichten |
| US20080152629A1 (en) * | 2000-12-06 | 2008-06-26 | James Edinger | Placental stem cell populations |
| DK1349918T3 (da) | 2000-12-06 | 2014-11-10 | Anthrogenesis Corp | Fremgangsmåde til indsamling af stamceller fra moderkagen |
| US7311905B2 (en) * | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
| EP2316919B1 (en) * | 2001-02-14 | 2015-10-07 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| EP3246396B1 (en) * | 2001-02-14 | 2020-01-29 | Celularity, Inc. | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
| US7498171B2 (en) * | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| WO2005094353A2 (en) * | 2004-03-29 | 2005-10-13 | Cytomatrix, Llc | Methods for production of regulatory t cells and uses thereof |
| DK1957633T3 (en) * | 2005-10-13 | 2014-03-17 | Anthrogenesis Corp | Immunomodulation USING PLACE SPEECH STEM CELLS |
| CN101389754A (zh) | 2005-12-29 | 2009-03-18 | 人类起源公司 | 胎盘干细胞和第二来源干细胞的联合培养 |
| PT2471904T (pt) | 2005-12-29 | 2019-02-25 | Celularity Inc | População de células estaminais placentárias |
| NZ570614A (en) * | 2006-01-23 | 2012-07-27 | Athersys Inc | Multipotent adult progenitor cell treatment of brain injuries and diseases |
| EP2023717B1 (en) * | 2006-05-11 | 2016-04-13 | Anthrogenesis Corporation | Methods for collecting placenta cord blood stem cells |
| ZA200902233B (en) * | 2006-10-23 | 2010-07-28 | Anthrogenesis Corp | Methods and compositions for treatment of bone defects with placental cell populations |
| AU2008216748A1 (en) * | 2007-02-12 | 2008-08-21 | Anthrogenesis Corporation | Hepatocytes and chondrocytes from adherent placental stem cells; and CD34+, CD45- placental stem cell-enriched cell populations |
| EP2164953A4 (en) * | 2007-06-18 | 2010-06-30 | Childrens Hosp & Res Ct Oak | METHOD OF ISOLATING STAIN AND PRECIPITATING CELLS FROM PLAZENTA |
| CA2700613C (en) * | 2007-09-26 | 2022-09-20 | Celgene Cellular Therapeutics | Angiogenic cells from human placental perfusate |
| NZ599825A (en) | 2007-09-28 | 2014-10-31 | Anthrogenesis Corp | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| NZ592839A (en) | 2008-11-21 | 2012-10-26 | Anthrogenesis Corp | Treatment of diseases, disorders or conditions of the lung using placental cells |
| WO2010105144A2 (en) * | 2009-03-12 | 2010-09-16 | University Of South Florida | Method of disease-induced and receptor-mediated stem cell neuroprotection |
| US20100323446A1 (en) * | 2009-06-05 | 2010-12-23 | Jill Renee Barnett | Method of collecting placental cells |
| US20120177618A1 (en) * | 2009-07-14 | 2012-07-12 | Massachusetts Institute Of Technology | Hematopoietic stromal progenitor cells and uses thereof |
| US20110280849A1 (en) | 2010-03-26 | 2011-11-17 | Anthrogenesis Corporation | Tumor suppression using human placenta-derived intermediate natural killer cells and immunomodulatory compounds |
| LT2556145T (lt) * | 2010-04-07 | 2016-11-10 | Anthrogenesis Corporation | Angiogenezė naudojant placentos kamienines ląsteles |
| ES2666746T3 (es) * | 2010-07-13 | 2018-05-07 | Anthrogenesis Corporation | Métodos para generar linfocitos citolíticos naturales |
| MX2013006592A (es) * | 2010-12-17 | 2014-02-06 | Anthrogenesis Corp | Tratamiento de lesion de la medula espinal y lesion traumatica de cerebro empleando celulas adherentes obtenidas del amnios. |
| KR20130128438A (ko) * | 2010-12-17 | 2013-11-26 | 안트로제네시스 코포레이션 | 양막 유래 부착성 세포를 사용한, 면역-관련 질환 및 장애의 치료 |
| US20120171180A1 (en) | 2010-12-30 | 2012-07-05 | Sascha Abramson | Compositions comprising amnion derived adherent cells and platelet-rich plasma |
| WO2013055476A1 (en) | 2011-09-09 | 2013-04-18 | Anthrogenesis Corporation | Treatment of amyotrophic lateral sclerosis using placental stem cells |
| JP2015526088A (ja) * | 2012-08-13 | 2015-09-10 | アントフロゲネシス コーポレーション | ナチュラルキラー細胞及びその使用 |
| EP2909314B1 (en) | 2012-10-19 | 2020-12-02 | Celularity, Inc. | Treatment of pain using amnion derived adherent cells |
-
2014
- 2014-11-14 CN CN201480073194.6A patent/CN105916521A/zh active Pending
- 2014-11-14 KR KR1020247005001A patent/KR20240023709A/ko not_active Ceased
- 2014-11-14 WO PCT/US2014/065665 patent/WO2015073800A2/en not_active Ceased
- 2014-11-14 CN CN202110968902.4A patent/CN113679740A/zh active Pending
- 2014-11-14 KR KR1020167015654A patent/KR20160098244A/ko not_active Ceased
- 2014-11-14 MX MX2016006270A patent/MX2016006270A/es unknown
- 2014-11-14 AU AU2014348454A patent/AU2014348454A1/en not_active Abandoned
- 2014-11-14 RU RU2016123361A patent/RU2016123361A/ru unknown
- 2014-11-14 CA CA2930573A patent/CA2930573C/en active Active
- 2014-11-14 KR KR1020217030425A patent/KR20210121277A/ko not_active Ceased
- 2014-11-14 JP JP2016530925A patent/JP2016537362A/ja active Pending
- 2014-11-14 EP EP14862931.4A patent/EP3068432A4/en not_active Withdrawn
- 2014-11-14 US US15/036,649 patent/US20160279171A1/en not_active Abandoned
-
2016
- 2016-05-13 MX MX2021003799A patent/MX2021003799A/es unknown
- 2016-05-13 ZA ZA2016/03270A patent/ZA201603270B/en unknown
-
2018
- 2018-11-23 US US16/199,116 patent/US20190117705A1/en not_active Abandoned
-
2019
- 2019-09-06 JP JP2019162780A patent/JP2020019777A/ja not_active Withdrawn
-
2020
- 2020-03-27 AU AU2020202182A patent/AU2020202182A1/en not_active Abandoned
-
2021
- 2021-09-24 JP JP2021155038A patent/JP2022020622A/ja not_active Withdrawn
-
2022
- 2022-08-12 AU AU2022215291A patent/AU2022215291A1/en not_active Abandoned
-
2023
- 2023-10-12 JP JP2023176697A patent/JP2024016037A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20160279171A1 (en) | 2016-09-29 |
| KR20240023709A (ko) | 2024-02-22 |
| AU2022215291A9 (en) | 2022-11-24 |
| EP3068432A4 (en) | 2017-04-19 |
| CA2930573A1 (en) | 2015-05-21 |
| JP2016537362A (ja) | 2016-12-01 |
| AU2022215291A1 (en) | 2022-09-01 |
| WO2015073800A2 (en) | 2015-05-21 |
| ZA201603270B (en) | 2022-09-28 |
| CN105916521A (zh) | 2016-08-31 |
| JP2022020622A (ja) | 2022-02-01 |
| CN113679740A (zh) | 2021-11-23 |
| JP2024016037A (ja) | 2024-02-06 |
| AU2020202182A1 (en) | 2020-04-16 |
| KR20210121277A (ko) | 2021-10-07 |
| AU2014348454A1 (en) | 2016-06-02 |
| JP2020019777A (ja) | 2020-02-06 |
| WO2015073800A8 (en) | 2015-12-17 |
| MX2016006270A (es) | 2016-09-07 |
| KR20160098244A (ko) | 2016-08-18 |
| US20190117705A1 (en) | 2019-04-25 |
| EP3068432A2 (en) | 2016-09-21 |
| CA2930573C (en) | 2023-12-05 |
| MX2021003799A (es) | 2021-06-04 |
| WO2015073800A3 (en) | 2015-07-02 |
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