RU2016116816A - Терапия с использованием клеток из плаценты человека и гематопоэтических клеток - Google Patents
Терапия с использованием клеток из плаценты человека и гематопоэтических клеток Download PDFInfo
- Publication number
- RU2016116816A RU2016116816A RU2016116816A RU2016116816A RU2016116816A RU 2016116816 A RU2016116816 A RU 2016116816A RU 2016116816 A RU2016116816 A RU 2016116816A RU 2016116816 A RU2016116816 A RU 2016116816A RU 2016116816 A RU2016116816 A RU 2016116816A
- Authority
- RU
- Russia
- Prior art keywords
- cells
- ucb
- paragraphs
- individual
- placental perfusate
- Prior art date
Links
- 210000002826 placenta Anatomy 0.000 title claims 2
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 238000000034 method Methods 0.000 claims 42
- 210000004027 cell Anatomy 0.000 claims 32
- 230000003169 placental effect Effects 0.000 claims 20
- 210000005087 mononuclear cell Anatomy 0.000 claims 11
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 9
- 210000004700 fetal blood Anatomy 0.000 claims 6
- 206010068051 Chimerism Diseases 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 230000010412 perfusion Effects 0.000 claims 4
- 208000024891 symptom Diseases 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 210000002449 bone cell Anatomy 0.000 claims 2
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 208000014951 hematologic disease Diseases 0.000 claims 2
- 208000030159 metabolic disease Diseases 0.000 claims 2
- 210000005259 peripheral blood Anatomy 0.000 claims 2
- 239000011886 peripheral blood Substances 0.000 claims 2
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 1
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 1
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 1
- 201000011452 Adrenoleukodystrophy Diseases 0.000 claims 1
- 208000031277 Amaurotic familial idiocy Diseases 0.000 claims 1
- 208000032467 Aplastic anaemia Diseases 0.000 claims 1
- 208000015872 Gaucher disease Diseases 0.000 claims 1
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 1
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 1
- 102000009030 Member 1 Subfamily D ATP Binding Cassette Transporter Human genes 0.000 claims 1
- 108010049137 Member 1 Subfamily D ATP Binding Cassette Transporter Proteins 0.000 claims 1
- 201000011442 Metachromatic leukodystrophy Diseases 0.000 claims 1
- 208000002678 Mucopolysaccharidoses Diseases 0.000 claims 1
- 201000003793 Myelodysplastic syndrome Diseases 0.000 claims 1
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims 1
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 1
- 208000026589 Wolman disease Diseases 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 208000005980 beta thalassemia Diseases 0.000 claims 1
- 201000008049 fucosidosis Diseases 0.000 claims 1
- 208000024908 graft versus host disease Diseases 0.000 claims 1
- 206010028093 mucopolysaccharidosis Diseases 0.000 claims 1
- 208000002491 severe combined immunodeficiency Diseases 0.000 claims 1
- 208000007056 sickle cell anemia Diseases 0.000 claims 1
- 206010043554 thrombocytopenia Diseases 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361886648P | 2013-10-03 | 2013-10-03 | |
| US61/886,648 | 2013-10-03 | ||
| US201361890057P | 2013-10-11 | 2013-10-11 | |
| US61/890,057 | 2013-10-11 | ||
| PCT/US2014/058774 WO2015051088A1 (en) | 2013-10-03 | 2014-10-02 | Therapy with cells from human placenta and hematopoietic cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019131152A Division RU2019131152A (ru) | 2013-10-03 | 2014-10-02 | Терапия с использованием клеток из плаценты человека и гематопоэтических клеток |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2016116816A true RU2016116816A (ru) | 2017-11-13 |
| RU2016116816A3 RU2016116816A3 (enExample) | 2018-08-02 |
Family
ID=52779130
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016116816A RU2016116816A (ru) | 2013-10-03 | 2014-10-02 | Терапия с использованием клеток из плаценты человека и гематопоэтических клеток |
| RU2019131152A RU2019131152A (ru) | 2013-10-03 | 2014-10-02 | Терапия с использованием клеток из плаценты человека и гематопоэтических клеток |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019131152A RU2019131152A (ru) | 2013-10-03 | 2014-10-02 | Терапия с использованием клеток из плаценты человека и гематопоэтических клеток |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10179152B2 (enExample) |
| EP (1) | EP3052109B8 (enExample) |
| JP (4) | JP2016531889A (enExample) |
| KR (3) | KR20160102965A (enExample) |
| CN (1) | CN105792834A (enExample) |
| AU (3) | AU2014329513A1 (enExample) |
| CA (1) | CA2926199C (enExample) |
| DK (1) | DK3052109T3 (enExample) |
| MX (2) | MX2016004209A (enExample) |
| RU (2) | RU2016116816A (enExample) |
| WO (1) | WO2015051088A1 (enExample) |
| ZA (1) | ZA201602151B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10426796B2 (en) | 2016-06-13 | 2019-10-01 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US10456423B2 (en) | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US11285177B2 (en) | 2018-01-03 | 2022-03-29 | Globus Medical, Inc. | Allografts containing viable cells and methods thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5437994A (en) * | 1989-06-15 | 1995-08-01 | Regents Of The University Of Michigan | Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
| IL107483A0 (en) * | 1993-11-03 | 1994-02-27 | Yeda Res & Dev | Bone marrow transplantation |
| WO2002064755A2 (en) * | 2001-02-14 | 2002-08-22 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| BRPI0407427A (pt) * | 2003-02-13 | 2006-01-24 | Anthrogenesis Corp | Método para tratar um paciente e para tratar a mielodisplasia |
| WO2007079184A2 (en) * | 2005-12-29 | 2007-07-12 | Anthrogenesis Corporation | Co-culture of placental stem cells and stem cells from a second source |
| EP1987135A2 (en) * | 2006-01-27 | 2008-11-05 | Auxocell Laboratories, Inc. | Methods and compositions relating to stem cell transplantation |
| JP5260499B2 (ja) * | 2006-05-11 | 2013-08-14 | コード ブラッド サイエンス インコーポレイテッド | 臍帯血幹細胞の回収方法及び使用方法 |
| US8263065B2 (en) * | 2007-09-28 | 2012-09-11 | Anthrogenesis Corporation | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
-
2014
- 2014-10-02 WO PCT/US2014/058774 patent/WO2015051088A1/en not_active Ceased
- 2014-10-02 RU RU2016116816A patent/RU2016116816A/ru unknown
- 2014-10-02 RU RU2019131152A patent/RU2019131152A/ru unknown
- 2014-10-02 AU AU2014329513A patent/AU2014329513A1/en not_active Abandoned
- 2014-10-02 MX MX2016004209A patent/MX2016004209A/es unknown
- 2014-10-02 KR KR1020167011298A patent/KR20160102965A/ko not_active Ceased
- 2014-10-02 CA CA2926199A patent/CA2926199C/en active Active
- 2014-10-02 DK DK14850630.6T patent/DK3052109T3/da active
- 2014-10-02 JP JP2016519848A patent/JP2016531889A/ja active Pending
- 2014-10-02 KR KR1020227010134A patent/KR20220044384A/ko not_active Ceased
- 2014-10-02 KR KR1020217013395A patent/KR20210054046A/ko not_active Ceased
- 2014-10-02 US US15/026,896 patent/US10179152B2/en active Active
- 2014-10-02 CN CN201480066174.6A patent/CN105792834A/zh active Pending
- 2014-10-02 EP EP14850630.6A patent/EP3052109B8/en active Active
-
2016
- 2016-03-31 ZA ZA2016/02151A patent/ZA201602151B/en unknown
- 2016-04-01 MX MX2021003798A patent/MX2021003798A/es unknown
-
2019
- 2019-06-18 JP JP2019112450A patent/JP2019194211A/ja not_active Withdrawn
-
2020
- 2020-03-23 AU AU2020202076A patent/AU2020202076A1/en not_active Abandoned
-
2021
- 2021-04-07 JP JP2021065060A patent/JP2021107407A/ja not_active Withdrawn
-
2022
- 2022-08-10 AU AU2022215207A patent/AU2022215207A1/en not_active Abandoned
-
2023
- 2023-02-27 JP JP2023027978A patent/JP2023078156A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220044384A (ko) | 2022-04-07 |
| EP3052109B8 (en) | 2021-06-23 |
| AU2022215207A1 (en) | 2022-09-01 |
| KR20210054046A (ko) | 2021-05-12 |
| RU2019131152A3 (enExample) | 2022-02-24 |
| MX2021003798A (es) | 2021-05-27 |
| NZ718571A (en) | 2023-12-22 |
| KR20160102965A (ko) | 2016-08-31 |
| AU2014329513A1 (en) | 2016-04-28 |
| EP3052109B1 (en) | 2021-05-12 |
| JP2023078156A (ja) | 2023-06-06 |
| JP2021107407A (ja) | 2021-07-29 |
| RU2019131152A (ru) | 2019-11-11 |
| WO2015051088A1 (en) | 2015-04-09 |
| US20160235790A1 (en) | 2016-08-18 |
| CA2926199C (en) | 2022-05-17 |
| DK3052109T3 (da) | 2021-08-16 |
| CN105792834A (zh) | 2016-07-20 |
| MX2016004209A (es) | 2016-07-11 |
| ZA201602151B (en) | 2022-12-21 |
| JP2016531889A (ja) | 2016-10-13 |
| CA2926199A1 (en) | 2015-04-09 |
| US10179152B2 (en) | 2019-01-15 |
| JP2019194211A (ja) | 2019-11-07 |
| EP3052109A1 (en) | 2016-08-10 |
| AU2020202076A1 (en) | 2020-04-09 |
| RU2016116816A3 (enExample) | 2018-08-02 |
| EP3052109A4 (en) | 2017-05-03 |
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