JP2008536930A5 - - Google Patents
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- Publication number
- JP2008536930A5 JP2008536930A5 JP2008507782A JP2008507782A JP2008536930A5 JP 2008536930 A5 JP2008536930 A5 JP 2008536930A5 JP 2008507782 A JP2008507782 A JP 2008507782A JP 2008507782 A JP2008507782 A JP 2008507782A JP 2008536930 A5 JP2008536930 A5 JP 2008536930A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- composition
- relatively pure
- ischemic tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000003719 b-lymphocyte Anatomy 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 12
- 210000001519 tissue Anatomy 0.000 claims 10
- 230000000302 ischemic effect Effects 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 8
- 241001465754 Metazoa Species 0.000 claims 7
- 238000000034 method Methods 0.000 claims 5
- 210000000130 stem cell Anatomy 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 3
- 108091008875 B cell receptors Proteins 0.000 claims 2
- 102100024222 B-lymphocyte antigen CD19 Human genes 0.000 claims 2
- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 210000005003 heart tissue Anatomy 0.000 claims 2
- 210000001165 lymph node Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 210000000952 spleen Anatomy 0.000 claims 2
- 230000004083 survival effect Effects 0.000 claims 2
- 241000282412 Homo Species 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67241605P | 2005-04-18 | 2005-04-18 | |
| PCT/US2006/014445 WO2006113647A2 (en) | 2005-04-18 | 2006-04-18 | Recovery of tissue function following administration of b cells to injured tissue |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008536930A JP2008536930A (ja) | 2008-09-11 |
| JP2008536930A5 true JP2008536930A5 (enExample) | 2010-07-15 |
| JP4659092B2 JP4659092B2 (ja) | 2011-03-30 |
Family
ID=37115830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008507782A Active JP4659092B2 (ja) | 2005-04-18 | 2006-04-18 | 損傷組織へのｂ細胞投与による組織機能の回復 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7695712B2 (enExample) |
| EP (1) | EP1877544B1 (enExample) |
| JP (1) | JP4659092B2 (enExample) |
| AT (1) | ATE537249T1 (enExample) |
| WO (1) | WO2006113647A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006113647A2 (en) * | 2005-04-18 | 2006-10-26 | Actx, Inc. | Recovery of tissue function following administration of b cells to injured tissue |
| US9220813B2 (en) * | 2005-04-18 | 2015-12-29 | Holy Cross Hospital, Inc. | Cell therapy for limiting overzealous inflammatory reactions in tissue healing |
| WO2008103336A1 (en) * | 2007-02-21 | 2008-08-28 | Cook Incorporated | Methods for intravascular engraftment in heart |
| KR101922118B1 (ko) | 2012-08-27 | 2018-11-26 | 삼성전자주식회사 | 플렉서블 반도체소자 및 그 제조방법 |
| EP2943206A4 (en) * | 2013-01-12 | 2017-01-04 | Cesca Therapeutics Inc. | Rapid infusion of autologous bone marrow derived stem cells |
| EP3593810B1 (en) | 2013-10-28 | 2021-06-23 | Biocardia, Inc. | Methods of measuring potential for therapeutic potency and defining dosages for autologous cell therapies |
| US9775816B2 (en) | 2013-11-07 | 2017-10-03 | The General Hospital Corporation | Eluting matrix and uses thereof |
| CN113677354A (zh) * | 2019-01-23 | 2021-11-19 | 综合医院公司 | B细胞免疫疗法 |
| WO2021211997A1 (en) * | 2020-04-16 | 2021-10-21 | The General Hospital Corporation | B cell immunomodulatory therapy for acute respiratory distress syndrome |
| EP4236968A4 (en) * | 2020-10-30 | 2024-03-27 | Immusoft Corporation | Methods of administering genetically modified b cells for in vivo delivery of therapeutic agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965132A (en) * | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US6465251B1 (en) * | 1996-11-13 | 2002-10-15 | Dana-Farber Cancer Institute, Inc. | Method of promoting b-cell proliferation and activation with CD40 ligand and cyclosporin |
| CA2505924A1 (en) | 2002-11-13 | 2004-05-27 | Micromet Ag | Method for identifying antigen specific b cells |
| WO2006113647A2 (en) | 2005-04-18 | 2006-10-26 | Actx, Inc. | Recovery of tissue function following administration of b cells to injured tissue |
-
2006
- 2006-04-18 WO PCT/US2006/014445 patent/WO2006113647A2/en not_active Ceased
- 2006-04-18 JP JP2008507782A patent/JP4659092B2/ja active Active
- 2006-04-18 EP EP06750473A patent/EP1877544B1/en active Active
- 2006-04-18 AT AT06750473T patent/ATE537249T1/de active
- 2006-04-18 US US11/406,508 patent/US7695712B2/en active Active
-
2010
- 2010-03-23 US US12/729,653 patent/US8603463B2/en active Active
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