RU2015155831A - Аденилатциклаза, некомпетентная по циклическому аденозин монофосфату, композиция и способы для лечения сердечной недостаточности и улучшения сердечной функции - Google Patents

Аденилатциклаза, некомпетентная по циклическому аденозин монофосфату, композиция и способы для лечения сердечной недостаточности и улучшения сердечной функции Download PDF

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RU2015155831A
RU2015155831A RU2015155831A RU2015155831A RU2015155831A RU 2015155831 A RU2015155831 A RU 2015155831A RU 2015155831 A RU2015155831 A RU 2015155831A RU 2015155831 A RU2015155831 A RU 2015155831A RU 2015155831 A RU2015155831 A RU 2015155831A
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ac6mut
heart
gene
nucleic acid
vector
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RU2015155831A
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Russian (ru)
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RU2015155831A3 (enExample
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Х. Кирк Хэммонд
Мей Хуа ГАО
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Те Риджентс Оф Те Юниверсити Оф Калифорния
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y406/00Phosphorus-oxygen lyases (4.6)
    • C12Y406/01Phosphorus-oxygen lyases (4.6.1)
    • C12Y406/01001Aodenylate cyclase (4.6.1.1)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2015155831A 2013-06-07 2014-06-04 Аденилатциклаза, некомпетентная по циклическому аденозин монофосфату, композиция и способы для лечения сердечной недостаточности и улучшения сердечной функции RU2015155831A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361832759P 2013-06-07 2013-06-07
US61/832,759 2013-06-07
PCT/US2014/040948 WO2014197624A1 (en) 2013-06-07 2014-06-04 Cycle adenosine monophosphate-incompetent adenylyl cyclase and compositions and methods for treating heart failure and increasing cardiac function

Publications (2)

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RU2015155831A true RU2015155831A (ru) 2017-07-14
RU2015155831A3 RU2015155831A3 (enExample) 2018-03-28

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RU2015155831A RU2015155831A (ru) 2013-06-07 2014-06-04 Аденилатциклаза, некомпетентная по циклическому аденозин монофосфату, композиция и способы для лечения сердечной недостаточности и улучшения сердечной функции

Country Status (14)

Country Link
US (1) US11040091B2 (enExample)
EP (1) EP3004343B1 (enExample)
JP (1) JP6571069B2 (enExample)
KR (1) KR20160032090A (enExample)
CN (1) CN105452458A (enExample)
AU (1) AU2014274902B2 (enExample)
BR (1) BR112015030355A8 (enExample)
CA (1) CA2914029A1 (enExample)
DK (1) DK3004343T3 (enExample)
HK (1) HK1222884A1 (enExample)
IL (1) IL242885B (enExample)
RU (1) RU2015155831A (enExample)
WO (1) WO2014197624A1 (enExample)
ZA (1) ZA201508942B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10293059B2 (en) * 2015-04-09 2019-05-21 Cornell University Gene therapy to prevent reactions to allergens
WO2018080146A2 (ko) * 2016-10-24 2018-05-03 광주과학기술원 단백질 탈 인산화 효소 1 억제 펩타이드를 포함하는 혈관 질환 치료용 조성물
WO2018090036A1 (en) * 2016-11-14 2018-05-17 Renova Therapeutics, Inc. Method of protection for cardiac tissue
US11760987B2 (en) 2017-09-07 2023-09-19 The Regents Of The University Of California Compositions and methods for the treatment or prevention of heart failure
CN111542334B (zh) * 2017-09-29 2024-01-23 贝特基因 用于预防或治疗心律失常的药物组合物
JP2021526818A (ja) * 2018-06-08 2021-10-11 ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. 心筋症のためのaav心臓遺伝子治療
CN109010799B (zh) * 2018-07-09 2021-07-06 沣潮医药科技(上海)有限公司 RyR2蛋白或RyR2重组蛋白在制备抗心力衰竭药物中的用途
CN109191052B (zh) * 2018-10-22 2020-09-25 山东大学 一种多车型车辆路径优化方法、服务器及系统
CA3189740A1 (en) 2020-07-27 2022-02-03 Anjarium Biosciences Ag Compositions of dna molecules, methods of making therefor, and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1255822A2 (en) * 1999-12-27 2002-11-13 The Regents Of The University Of California Modified adenylylcyclase type vi useful in gene therapy for congestive heart failure

Also Published As

Publication number Publication date
US11040091B2 (en) 2021-06-22
IL242885B (en) 2019-12-31
ZA201508942B (en) 2019-05-29
AU2014274902B2 (en) 2020-06-04
DK3004343T3 (en) 2019-02-04
JP2016521708A (ja) 2016-07-25
EP3004343A1 (en) 2016-04-13
CA2914029A1 (en) 2014-12-11
WO2014197624A1 (en) 2014-12-11
AU2014274902A1 (en) 2015-12-24
RU2015155831A3 (enExample) 2018-03-28
KR20160032090A (ko) 2016-03-23
EP3004343B1 (en) 2018-10-10
BR112015030355A2 (pt) 2017-07-25
JP6571069B2 (ja) 2019-09-04
BR112015030355A8 (pt) 2019-12-24
CN105452458A (zh) 2016-03-30
US20160101164A1 (en) 2016-04-14
HK1222884A1 (zh) 2017-07-14
EP3004343A4 (en) 2017-01-04

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Effective date: 20201111