RU2015118217A - Способ кристаллизации трициклических индольных производных - Google Patents
Способ кристаллизации трициклических индольных производных Download PDFInfo
- Publication number
- RU2015118217A RU2015118217A RU2015118217A RU2015118217A RU2015118217A RU 2015118217 A RU2015118217 A RU 2015118217A RU 2015118217 A RU2015118217 A RU 2015118217A RU 2015118217 A RU2015118217 A RU 2015118217A RU 2015118217 A RU2015118217 A RU 2015118217A
- Authority
- RU
- Russia
- Prior art keywords
- formula
- compound
- hydrogen
- composition according
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3689DE2012 | 2012-11-30 | ||
| IN3689/DEL/2012 | 2012-11-30 | ||
| GBGB1300647.3A GB201300647D0 (en) | 2013-01-15 | 2013-01-15 | Crystallization |
| GB1300647.3 | 2013-01-15 | ||
| PCT/EP2013/074986 WO2014083113A1 (en) | 2012-11-30 | 2013-11-28 | Crystallization process of tricyclic indole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015118217A true RU2015118217A (ru) | 2017-01-11 |
Family
ID=54266915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015118217A RU2015118217A (ru) | 2012-11-30 | 2013-11-28 | Способ кристаллизации трициклических индольных производных |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10709798B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2943195A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6280560B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20150088802A (cg-RX-API-DMAC7.html) |
| CN (2) | CN104837489A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2013351152A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112015012138A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2892485A1 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2015DN03978A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2015006871A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2015118217A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014083113A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2015118217A (ru) | 2012-11-30 | 2017-01-11 | ДжиИ ХЕЛТКЕР ЛИМИТЕД | Способ кристаллизации трициклических индольных производных |
| US20160144477A1 (en) * | 2014-11-21 | 2016-05-26 | Diane Scott | Coated compressive subpad for chemical mechanical polishing |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6177440B1 (en) * | 1996-10-30 | 2001-01-23 | Eli Lilly And Company | Substituted tricyclics |
| JP2001522884A (ja) | 1997-11-14 | 2001-11-20 | イーライ・リリー・アンド・カンパニー | アルツハイマー病の処置方法 |
| DZ2769A1 (fr) | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| JP2005527464A (ja) | 2001-08-09 | 2005-09-15 | イーライ・リリー・アンド・カンパニー | ｓＰＬＡ２インヒビターとしてのシクロヘプタＢインドール誘導体 |
| JP2005527466A (ja) | 2001-08-09 | 2005-09-15 | イーライ・リリー・アンド・カンパニー | ｓＰＬＡ２インヒビターとしてのシクロヘプトＢインドール誘導体 |
| GB0905328D0 (en) * | 2009-03-27 | 2009-05-13 | Ge Healthcare Ltd | Indole derivatives |
| CN102834379B (zh) | 2010-03-26 | 2014-12-24 | 通用电气健康护理有限公司 | 作为pbr配体的三环吲哚衍生物 |
| GB201016038D0 (en) | 2010-09-24 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method |
| GB201016411D0 (en) | 2010-09-30 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method for cancer |
| GB201021263D0 (en) | 2010-12-15 | 2011-01-26 | Ge Healthcare Ltd | Solid phase extraction method |
| US9220795B2 (en) * | 2011-09-22 | 2015-12-29 | Ge Healthcare Limited | Indole derivatives |
| RU2015118217A (ru) | 2012-11-30 | 2017-01-11 | ДжиИ ХЕЛТКЕР ЛИМИТЕД | Способ кристаллизации трициклических индольных производных |
-
2013
- 2013-11-28 RU RU2015118217A patent/RU2015118217A/ru not_active Application Discontinuation
- 2013-11-28 EP EP13796090.2A patent/EP2943195A1/en not_active Withdrawn
- 2013-11-28 JP JP2015544462A patent/JP6280560B2/ja active Active
- 2013-11-28 KR KR1020157013974A patent/KR20150088802A/ko not_active Withdrawn
- 2013-11-28 MX MX2015006871A patent/MX2015006871A/es unknown
- 2013-11-28 CN CN201380062872.4A patent/CN104837489A/zh active Pending
- 2013-11-28 AU AU2013351152A patent/AU2013351152A1/en not_active Abandoned
- 2013-11-28 IN IN3978DEN2015 patent/IN2015DN03978A/en unknown
- 2013-11-28 US US14/648,353 patent/US10709798B2/en active Active
- 2013-11-28 CN CN202010090283.9A patent/CN111362863A/zh active Pending
- 2013-11-28 CA CA2892485A patent/CA2892485A1/en not_active Abandoned
- 2013-11-28 WO PCT/EP2013/074986 patent/WO2014083113A1/en not_active Ceased
- 2013-11-28 BR BR112015012138A patent/BR112015012138A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015006871A (es) | 2015-09-16 |
| CN104837489A (zh) | 2015-08-12 |
| IN2015DN03978A (cg-RX-API-DMAC7.html) | 2015-10-02 |
| US20150335766A1 (en) | 2015-11-26 |
| JP2016507477A (ja) | 2016-03-10 |
| CN111362863A (zh) | 2020-07-03 |
| AU2013351152A1 (en) | 2015-05-21 |
| BR112015012138A2 (pt) | 2017-07-11 |
| EP2943195A1 (en) | 2015-11-18 |
| US10709798B2 (en) | 2020-07-14 |
| CA2892485A1 (en) | 2014-06-05 |
| JP6280560B2 (ja) | 2018-02-14 |
| WO2014083113A1 (en) | 2014-06-05 |
| KR20150088802A (ko) | 2015-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20161129 |