MX2015006871A - Proceso de cristalizacion de derivados de indoles triciclicos. - Google Patents
Proceso de cristalizacion de derivados de indoles triciclicos.Info
- Publication number
- MX2015006871A MX2015006871A MX2015006871A MX2015006871A MX2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A
- Authority
- MX
- Mexico
- Prior art keywords
- composition
- tricyclic indole
- crystallization process
- indole derivatives
- tricyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
Abstract
La presente invención se refiere a una composición comprendiendo un compuesto de indol tricíclico. La composición tiene una mayor pureza y mejor perfil de impureza que las composiciones conocidas comprendiendo dicho compuesto de indol tricíclico y como una consecuencia tiene propiedades superiores, en particular cuando dicho compuesto es destinado para uso in vivo como un agente terapéutico o diagnóstico. También se proporciona mediante la presente invención un método para hacer la composición de la invención, una composición farmacéutica comprendiendo la composición de la invención y el uso de la composición de la invención en un método médico.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3689DE2012 | 2012-11-30 | ||
GBGB1300647.3A GB201300647D0 (en) | 2013-01-15 | 2013-01-15 | Crystallization |
PCT/EP2013/074986 WO2014083113A1 (en) | 2012-11-30 | 2013-11-28 | Crystallization process of tricyclic indole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015006871A true MX2015006871A (es) | 2015-09-16 |
Family
ID=54266915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015006871A MX2015006871A (es) | 2012-11-30 | 2013-11-28 | Proceso de cristalizacion de derivados de indoles triciclicos. |
Country Status (12)
Country | Link |
---|---|
US (1) | US10709798B2 (es) |
EP (1) | EP2943195A1 (es) |
JP (1) | JP6280560B2 (es) |
KR (1) | KR20150088802A (es) |
CN (2) | CN104837489A (es) |
AU (1) | AU2013351152A1 (es) |
BR (1) | BR112015012138A2 (es) |
CA (1) | CA2892485A1 (es) |
IN (1) | IN2015DN03978A (es) |
MX (1) | MX2015006871A (es) |
RU (1) | RU2015118217A (es) |
WO (1) | WO2014083113A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20150088802A (ko) | 2012-11-30 | 2015-08-03 | 지이 헬쓰케어 리미티드 | 트리시클릭 인돌 유도체의 결정화 방법 |
US20160144477A1 (en) * | 2014-11-21 | 2016-05-26 | Diane Scott | Coated compressive subpad for chemical mechanical polishing |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6177440B1 (en) * | 1996-10-30 | 2001-01-23 | Eli Lilly And Company | Substituted tricyclics |
JP2001522884A (ja) | 1997-11-14 | 2001-11-20 | イーライ・リリー・アンド・カンパニー | アルツハイマー病の処置方法 |
DZ2769A1 (fr) | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
JP2005527464A (ja) | 2001-08-09 | 2005-09-15 | イーライ・リリー・アンド・カンパニー | sPLA2インヒビターとしてのシクロヘプタBインドール誘導体 |
DE60208065T2 (de) | 2001-08-09 | 2006-07-13 | Eli Lilly And Co., Indianapolis | Cyclohept'b! indolderivate als spla2-inhibitoren |
GB0905328D0 (en) * | 2009-03-27 | 2009-05-13 | Ge Healthcare Ltd | Indole derivatives |
ES2688574T3 (es) | 2010-03-26 | 2018-11-05 | Ge Healthcare Limited | Derivados de indol tricíclicos como ligandos de PBR |
GB201016038D0 (en) | 2010-09-24 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method |
GB201016411D0 (en) | 2010-09-30 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method for cancer |
GB201021263D0 (en) | 2010-12-15 | 2011-01-26 | Ge Healthcare Ltd | Solid phase extraction method |
US9220795B2 (en) * | 2011-09-22 | 2015-12-29 | Ge Healthcare Limited | Indole derivatives |
KR20150088802A (ko) | 2012-11-30 | 2015-08-03 | 지이 헬쓰케어 리미티드 | 트리시클릭 인돌 유도체의 결정화 방법 |
-
2013
- 2013-11-28 KR KR1020157013974A patent/KR20150088802A/ko not_active Application Discontinuation
- 2013-11-28 JP JP2015544462A patent/JP6280560B2/ja active Active
- 2013-11-28 US US14/648,353 patent/US10709798B2/en active Active
- 2013-11-28 RU RU2015118217A patent/RU2015118217A/ru not_active Application Discontinuation
- 2013-11-28 MX MX2015006871A patent/MX2015006871A/es unknown
- 2013-11-28 BR BR112015012138A patent/BR112015012138A2/pt not_active IP Right Cessation
- 2013-11-28 EP EP13796090.2A patent/EP2943195A1/en not_active Withdrawn
- 2013-11-28 CN CN201380062872.4A patent/CN104837489A/zh active Pending
- 2013-11-28 AU AU2013351152A patent/AU2013351152A1/en not_active Abandoned
- 2013-11-28 WO PCT/EP2013/074986 patent/WO2014083113A1/en active Application Filing
- 2013-11-28 CA CA2892485A patent/CA2892485A1/en not_active Abandoned
- 2013-11-28 CN CN202010090283.9A patent/CN111362863A/zh active Pending
- 2013-11-28 IN IN3978DEN2015 patent/IN2015DN03978A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN104837489A (zh) | 2015-08-12 |
US20150335766A1 (en) | 2015-11-26 |
JP6280560B2 (ja) | 2018-02-14 |
BR112015012138A2 (pt) | 2017-07-11 |
CA2892485A1 (en) | 2014-06-05 |
KR20150088802A (ko) | 2015-08-03 |
EP2943195A1 (en) | 2015-11-18 |
RU2015118217A (ru) | 2017-01-11 |
IN2015DN03978A (es) | 2015-10-02 |
AU2013351152A1 (en) | 2015-05-21 |
US10709798B2 (en) | 2020-07-14 |
WO2014083113A1 (en) | 2014-06-05 |
CN111362863A (zh) | 2020-07-03 |
JP2016507477A (ja) | 2016-03-10 |
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