RU2015113595A - Комбинация хромофоров для биофотонных применений - Google Patents
Комбинация хромофоров для биофотонных применений Download PDFInfo
- Publication number
- RU2015113595A RU2015113595A RU2015113595A RU2015113595A RU2015113595A RU 2015113595 A RU2015113595 A RU 2015113595A RU 2015113595 A RU2015113595 A RU 2015113595A RU 2015113595 A RU2015113595 A RU 2015113595A RU 2015113595 A RU2015113595 A RU 2015113595A
- Authority
- RU
- Russia
- Prior art keywords
- composition
- therapy
- xanthene dye
- xanthene
- biophoton
- Prior art date
Links
- 239000001018 xanthene dye Substances 0.000 claims abstract 47
- 238000002560 therapeutic procedure Methods 0.000 claims abstract 42
- SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 claims abstract 12
- SEACYXSIPDVVMV-UHFFFAOYSA-L eosin Y Chemical compound [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C([O-])=C(Br)C=C21 SEACYXSIPDVVMV-UHFFFAOYSA-L 0.000 claims abstract 12
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims abstract 12
- 230000000699 topical effect Effects 0.000 claims abstract 11
- 238000000862 absorption spectrum Methods 0.000 claims abstract 10
- 238000000295 emission spectrum Methods 0.000 claims abstract 4
- 230000004913 activation Effects 0.000 claims abstract 2
- 238000001429 visible spectrum Methods 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims 11
- 210000001519 tissue Anatomy 0.000 claims 11
- 210000003491 skin Anatomy 0.000 claims 6
- 208000017520 skin disease Diseases 0.000 claims 4
- 208000027418 Wounds and injury Diseases 0.000 claims 3
- 230000003213 activating effect Effects 0.000 claims 3
- 230000001678 irradiating effect Effects 0.000 claims 3
- 230000003716 rejuvenation Effects 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 230000031700 light absorption Effects 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 102100034871 C-C motif chemokine 8 Human genes 0.000 claims 1
- 101710155833 C-C motif chemokine 8 Proteins 0.000 claims 1
- 102100036150 C-X-C motif chemokine 5 Human genes 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 101100441523 Homo sapiens CXCL5 gene Proteins 0.000 claims 1
- 101000852968 Homo sapiens Interleukin-1 receptor-like 1 Proteins 0.000 claims 1
- 101001013150 Homo sapiens Interstitial collagenase Proteins 0.000 claims 1
- 101000990908 Homo sapiens Neutrophil collagenase Proteins 0.000 claims 1
- 101000990915 Homo sapiens Stromelysin-1 Proteins 0.000 claims 1
- 101000577874 Homo sapiens Stromelysin-2 Proteins 0.000 claims 1
- 101000585365 Homo sapiens Sulfotransferase 2A1 Proteins 0.000 claims 1
- 102000000380 Matrix Metalloproteinase 1 Human genes 0.000 claims 1
- 102100030411 Neutrophil collagenase Human genes 0.000 claims 1
- 206010072170 Skin wound Diseases 0.000 claims 1
- 102100030416 Stromelysin-1 Human genes 0.000 claims 1
- 102100028848 Stromelysin-2 Human genes 0.000 claims 1
- 102100029867 Sulfotransferase 2A1 Human genes 0.000 claims 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 210000004207 dermis Anatomy 0.000 claims 1
- 210000002615 epidermis Anatomy 0.000 claims 1
- 230000035876 healing Effects 0.000 claims 1
- 230000020169 heat generation Effects 0.000 claims 1
- AEUKDPKXTPNBNY-XEYRWQBLSA-N mcp 2 Chemical compound C([C@@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C)C1=CC=CC=C1 AEUKDPKXTPNBNY-XEYRWQBLSA-N 0.000 claims 1
- 239000007800 oxidant agent Substances 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 238000001228 spectrum Methods 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
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- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
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- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
- C09B67/0033—Blends of pigments; Mixtured crystals; Solid solutions
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- A61K2800/262—Transparent; Translucent
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
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- A61K2800/434—Luminescent, Fluorescent; Optical brighteners; Photosensitizers
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
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- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261701502P | 2012-09-14 | 2012-09-14 | |
| US201261701510P | 2012-09-14 | 2012-09-14 | |
| US201261701513P | 2012-09-14 | 2012-09-14 | |
| US61/701,502 | 2012-09-14 | ||
| US61/701,510 | 2012-09-14 | ||
| US61/701,513 | 2012-09-14 | ||
| US201361766611P | 2013-02-19 | 2013-02-19 | |
| US61/766,611 | 2013-02-19 | ||
| US13/830,488 US20130281913A1 (en) | 2012-04-20 | 2013-03-14 | Biophotonic compositions and methods for providing biophotonic treatment |
| US13/830,488 | 2013-03-14 | ||
| GB1307157.6 | 2013-04-19 | ||
| PCT/CA2013/000395 WO2013155620A1 (en) | 2012-04-20 | 2013-04-19 | Biophotonic compositions, kits and methods |
| CAPCT/CA2013/000395 | 2013-04-19 | ||
| GB1307157.6A GB2499921B (en) | 2012-04-20 | 2013-04-19 | Biophotonic compositions, kits and methods |
| US201361873791P | 2013-09-04 | 2013-09-04 | |
| US61/873,791 | 2013-09-04 | ||
| PCT/CA2013/000786 WO2014040176A1 (en) | 2012-09-14 | 2013-09-13 | Chromophore combinations for biophotonic uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015113595A true RU2015113595A (ru) | 2016-11-10 |
Family
ID=50277449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015113595A RU2015113595A (ru) | 2012-09-14 | 2013-09-13 | Комбинация хромофоров для биофотонных применений |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20190133908A1 (enExample) |
| EP (3) | EP2895194A4 (enExample) |
| JP (3) | JP2015528472A (enExample) |
| KR (3) | KR20180110240A (enExample) |
| CN (1) | CN104755101B (enExample) |
| AU (1) | AU2013315303B2 (enExample) |
| BR (1) | BR112015005382A2 (enExample) |
| HK (2) | HK1208807A1 (enExample) |
| IL (1) | IL237657A0 (enExample) |
| IN (1) | IN2015DN02938A (enExample) |
| MX (1) | MX367670B (enExample) |
| RU (1) | RU2015113595A (enExample) |
| WO (1) | WO2014040176A1 (enExample) |
| ZA (1) | ZA201501700B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180023070A (ko) | 2008-11-07 | 2018-03-06 | 클록스 테크놀로지스 인크. | 히알루론산, 글루코사민 또는 알란토인을 포함하는 산화성의 광활성화된 피부 회춘용 조성물 |
| SG177635A1 (en) | 2009-07-17 | 2012-03-29 | Klox Technologies Inc | Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease |
| US11116841B2 (en) | 2012-04-20 | 2021-09-14 | Klox Technologies Inc. | Biophotonic compositions, kits and methods |
| US20130281913A1 (en) | 2012-04-20 | 2013-10-24 | Klox Technologies Inc. | Biophotonic compositions and methods for providing biophotonic treatment |
| KR20180110240A (ko) * | 2012-09-14 | 2018-10-08 | 클록스 테크놀로지스 인크. | 생체 광자성 용도를 위한 발색단 조합 |
| BR112015005301A2 (pt) * | 2012-09-14 | 2017-07-04 | Klox Tech Inc | composições cosméticas biofotônicas |
| US20140276354A1 (en) | 2013-03-14 | 2014-09-18 | Klox Technologies Inc. | Biophotonic materials and uses thereof |
| WO2015000058A1 (en) * | 2013-07-03 | 2015-01-08 | Klox Technologies Inc. | Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds |
| JP2017509433A (ja) * | 2014-04-01 | 2017-04-06 | クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． | 組織充填剤組成物および使用方法 |
| AU2015271615A1 (en) * | 2014-06-04 | 2016-12-08 | Klox Technologies Inc. | Biophotonic hydrogels |
| WO2015189712A2 (en) * | 2014-06-09 | 2015-12-17 | Klox Technologies Inc. | Silicone-based biophotonic compositions and uses thereof |
| EP3193951A4 (en) * | 2014-09-15 | 2018-04-18 | Klox Technologies Inc. | Emissive polymeric matrices |
| EP3212826B1 (en) * | 2014-10-31 | 2020-10-14 | Klox Technologies Inc. | Photoactivatable fibers and fabric media |
| JP2016172705A (ja) * | 2015-03-17 | 2016-09-29 | 国立大学法人 東京大学 | Ｍｉｎｔ３阻害剤 |
| CA3011156A1 (en) * | 2016-01-11 | 2017-07-20 | Klox Technologies Limited | Biophotonic compositions for the treatment of otitis externa |
| JP2019501951A (ja) * | 2016-01-11 | 2019-01-24 | クロックス テクノロジーズ リミテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｉｍｉｔｅｄ | 薬剤非耐性及び薬剤耐性の感染症のどちらか又は両方を有する皮膚及び軟部組織の創傷を治療するためのバイオフォトニック組成物 |
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| JP2018076343A (ja) | 2018-05-17 |
| EP3329938A1 (en) | 2018-06-06 |
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| EP2895194A1 (en) | 2015-07-22 |
| IL237657A0 (en) | 2015-04-30 |
| IN2015DN02938A (enExample) | 2015-09-18 |
| BR112015005382A2 (pt) | 2019-11-26 |
| MX2015003361A (es) | 2015-10-22 |
| HK1208807A1 (en) | 2016-03-18 |
| AU2013315303A1 (en) | 2015-03-19 |
| CN104755101B (zh) | 2018-10-02 |
| JP2022003081A (ja) | 2022-01-11 |
| EP3153177A1 (en) | 2017-04-12 |
| EP3329938B1 (en) | 2021-06-23 |
| ZA201501700B (en) | 2016-01-27 |
| AU2013315303B2 (en) | 2018-07-26 |
| US20190133908A1 (en) | 2019-05-09 |
| KR20150068358A (ko) | 2015-06-19 |
| MX367670B (es) | 2019-08-30 |
| WO2014040176A1 (en) | 2014-03-20 |
| KR20210072827A (ko) | 2021-06-17 |
| HK1212592A1 (zh) | 2016-06-17 |
| CN104755101A (zh) | 2015-07-01 |
| EP2895194A4 (en) | 2016-03-09 |
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| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
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