JP2015528472A5 - - Google Patents
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- Publication number
- JP2015528472A5 JP2015528472A5 JP2015531408A JP2015531408A JP2015528472A5 JP 2015528472 A5 JP2015528472 A5 JP 2015528472A5 JP 2015531408 A JP2015531408 A JP 2015531408A JP 2015531408 A JP2015531408 A JP 2015531408A JP 2015528472 A5 JP2015528472 A5 JP 2015528472A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- xanthene
- eosin
- biophotonic
- fluorescein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000001018 xanthene dye Substances 0.000 claims 17
- SEACYXSIPDVVMV-UHFFFAOYSA-L eosin Y Chemical compound [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C([O-])=C(Br)C=C21 SEACYXSIPDVVMV-UHFFFAOYSA-L 0.000 claims 7
- 230000003287 optical effect Effects 0.000 claims 7
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims 6
- IICCLYANAQEHCI-UHFFFAOYSA-N 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one Chemical compound O1C(=O)C(C(=C(Cl)C(Cl)=C2Cl)Cl)=C2C21C1=CC(I)=C(O)C(I)=C1OC1=C(I)C(O)=C(I)C=C21 IICCLYANAQEHCI-UHFFFAOYSA-N 0.000 claims 4
- 229930187593 rose bengal Natural products 0.000 claims 4
- 229940081623 rose bengal Drugs 0.000 claims 4
- STRXNPAVPKGJQR-UHFFFAOYSA-N rose bengal A Natural products O1C(=O)C(C(=CC=C2Cl)Cl)=C2C21C1=CC(I)=C(O)C(I)=C1OC1=C(I)C(O)=C(I)C=C21 STRXNPAVPKGJQR-UHFFFAOYSA-N 0.000 claims 4
- 238000000862 absorption spectrum Methods 0.000 claims 3
- 238000000295 emission spectrum Methods 0.000 claims 3
- 230000004913 activation Effects 0.000 claims 2
- 230000031700 light absorption Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 238000001429 visible spectrum Methods 0.000 claims 2
- 102100034871 C-C motif chemokine 8 Human genes 0.000 claims 1
- 101710155833 C-C motif chemokine 8 Proteins 0.000 claims 1
- 102100036150 C-X-C motif chemokine 5 Human genes 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 101100441523 Homo sapiens CXCL5 gene Proteins 0.000 claims 1
- 101001013150 Homo sapiens Interstitial collagenase Proteins 0.000 claims 1
- 101000990908 Homo sapiens Neutrophil collagenase Proteins 0.000 claims 1
- 101000990915 Homo sapiens Stromelysin-1 Proteins 0.000 claims 1
- 101000577874 Homo sapiens Stromelysin-2 Proteins 0.000 claims 1
- 102000000380 Matrix Metalloproteinase 1 Human genes 0.000 claims 1
- 102100030411 Neutrophil collagenase Human genes 0.000 claims 1
- 241000220317 Rosa Species 0.000 claims 1
- 102100030416 Stromelysin-1 Human genes 0.000 claims 1
- 102100028848 Stromelysin-2 Human genes 0.000 claims 1
- 206010052428 Wound Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical group C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- AEUKDPKXTPNBNY-XEYRWQBLSA-N mcp 2 Chemical compound C([C@@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C)C1=CC=CC=C1 AEUKDPKXTPNBNY-XEYRWQBLSA-N 0.000 claims 1
- GVKCHTBDSMQENH-UHFFFAOYSA-L phloxine B Chemical compound [Na+].[Na+].[O-]C(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C([O-])=C(Br)C=C21 GVKCHTBDSMQENH-UHFFFAOYSA-L 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 230000003716 rejuvenation Effects 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261701502P | 2012-09-14 | 2012-09-14 | |
| US201261701510P | 2012-09-14 | 2012-09-14 | |
| US201261701513P | 2012-09-14 | 2012-09-14 | |
| US61/701,502 | 2012-09-14 | ||
| US61/701,513 | 2012-09-14 | ||
| US61/701,510 | 2012-09-14 | ||
| US201361766611P | 2013-02-19 | 2013-02-19 | |
| US61/766,611 | 2013-02-19 | ||
| US13/830,488 | 2013-03-14 | ||
| US13/830,488 US20130281913A1 (en) | 2012-04-20 | 2013-03-14 | Biophotonic compositions and methods for providing biophotonic treatment |
| GB1307157.6 | 2013-04-19 | ||
| CAPCT/CA2013/000395 | 2013-04-19 | ||
| GB1307157.6A GB2499921B (en) | 2012-04-20 | 2013-04-19 | Biophotonic compositions, kits and methods |
| PCT/CA2013/000395 WO2013155620A1 (en) | 2012-04-20 | 2013-04-19 | Biophotonic compositions, kits and methods |
| US201361873791P | 2013-09-04 | 2013-09-04 | |
| US61/873,791 | 2013-09-04 | ||
| PCT/CA2013/000786 WO2014040176A1 (en) | 2012-09-14 | 2013-09-13 | Chromophore combinations for biophotonic uses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017238941A Division JP2018076343A (ja) | 2012-09-14 | 2017-12-13 | 生体光使用のための発色団の組み合わせ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015528472A JP2015528472A (ja) | 2015-09-28 |
| JP2015528472A5 true JP2015528472A5 (enExample) | 2016-10-27 |
Family
ID=50277449
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015531408A Pending JP2015528472A (ja) | 2012-09-14 | 2013-09-13 | 生体光使用のための発色団の組み合わせ |
| JP2017238941A Pending JP2018076343A (ja) | 2012-09-14 | 2017-12-13 | 生体光使用のための発色団の組み合わせ |
| JP2021164474A Pending JP2022003081A (ja) | 2012-09-14 | 2021-10-06 | 生体光組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017238941A Pending JP2018076343A (ja) | 2012-09-14 | 2017-12-13 | 生体光使用のための発色団の組み合わせ |
| JP2021164474A Pending JP2022003081A (ja) | 2012-09-14 | 2021-10-06 | 生体光組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20190133908A1 (enExample) |
| EP (3) | EP2895194A4 (enExample) |
| JP (3) | JP2015528472A (enExample) |
| KR (3) | KR20180110240A (enExample) |
| CN (1) | CN104755101B (enExample) |
| AU (1) | AU2013315303B2 (enExample) |
| BR (1) | BR112015005382A2 (enExample) |
| HK (2) | HK1212592A1 (enExample) |
| IL (1) | IL237657A0 (enExample) |
| IN (1) | IN2015DN02938A (enExample) |
| MX (1) | MX367670B (enExample) |
| RU (1) | RU2015113595A (enExample) |
| WO (1) | WO2014040176A1 (enExample) |
| ZA (1) | ZA201501700B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA029534B1 (ru) | 2008-11-07 | 2018-04-30 | Клокс Текнолоджиз Инк. | Комбинация оксиданта и фотоактиватора для заживления ран |
| DK2453922T3 (en) | 2009-07-17 | 2018-01-02 | Klox Tech Inc | ANTIBACTERIAL ORAL COMPOSITION |
| US20130281913A1 (en) | 2012-04-20 | 2013-10-24 | Klox Technologies Inc. | Biophotonic compositions and methods for providing biophotonic treatment |
| US11116841B2 (en) | 2012-04-20 | 2021-09-14 | Klox Technologies Inc. | Biophotonic compositions, kits and methods |
| WO2014040176A1 (en) * | 2012-09-14 | 2014-03-20 | Klox Technologies Inc. | Chromophore combinations for biophotonic uses |
| IN2015DN02939A (enExample) * | 2012-09-14 | 2015-09-18 | Klox Technologies Inc | |
| US20140276354A1 (en) | 2013-03-14 | 2014-09-18 | Klox Technologies Inc. | Biophotonic materials and uses thereof |
| KR20210108505A (ko) | 2013-07-03 | 2021-09-02 | 광동 클록스 바이오메디컬 그룹 씨오., 엘티디 | 상처를 치료하기 위한 발색단과 겔화제를 포함하는 생체광자성 조성물 |
| WO2015149177A1 (en) | 2014-04-01 | 2015-10-08 | Klox Technologies Inc. | Tissue filler compositions and methods of use |
| AU2015271615A1 (en) * | 2014-06-04 | 2016-12-08 | Klox Technologies Inc. | Biophotonic hydrogels |
| US11266685B2 (en) | 2014-06-09 | 2022-03-08 | Klox Technologies Inc. | Silicone-based biophotonic compositions and uses thereof |
| CN106687151A (zh) * | 2014-09-15 | 2017-05-17 | 克洛克斯科技公司 | 发射性聚合物基质 |
| EP3212826B1 (en) * | 2014-10-31 | 2020-10-14 | Klox Technologies Inc. | Photoactivatable fibers and fabric media |
| JP2016172705A (ja) * | 2015-03-17 | 2016-09-29 | 国立大学法人 東京大学 | Ｍｉｎｔ３阻害剤 |
| US10610513B2 (en) * | 2016-01-11 | 2020-04-07 | Klox Technologies Limited | Biophotonic compositions for the treatment of otitis externa |
| WO2017120674A1 (en) | 2016-01-11 | 2017-07-20 | Klox Technologies Limited | Biophotonic compositions for treating skin and soft tissue wounds having either or both non-resistant and resistant infections |
| EP3402523A4 (en) * | 2016-01-11 | 2019-07-24 | Francesco Bellini | BIOPHOTONIC COMPOSITIONS FOR THE TREATMENT OF PYODERMA |
| WO2017201531A1 (en) * | 2016-05-20 | 2017-11-23 | Howard Hughes Medical Institute | Photoactive fluorophores and methods of in vivo labeling |
| WO2018053646A1 (en) | 2016-09-23 | 2018-03-29 | Klox Technologies Inc. | Biophotonic compositions, methods, and kits for inhibiting and disrupting biofilms |
| CA3037397A1 (en) * | 2016-09-23 | 2018-03-29 | Klox Technologies Inc. | Biophotonic compositions and methods for reducing scarring |
| CN110494165A (zh) * | 2017-01-27 | 2019-11-22 | 克洛克斯科技公司 | 使用自生物光子组合物或生物光子系统产生和发射的荧光进行生物过程的光生物调控的方法 |
| US20210170027A1 (en) * | 2017-11-17 | 2021-06-10 | Klox Technologies Limited | Biophotonic compositions, methods and kits for enhancing hair growth |
| AU2018367960A1 (en) * | 2017-11-17 | 2020-06-04 | Klox Technologies Limited | Modulation of biophotonic regimens |
| US10322297B1 (en) * | 2018-08-21 | 2019-06-18 | Lumia Group, LLC | Electrically passive low-level light therapy system and methods incorporating same |
| KR102730110B1 (ko) * | 2018-10-18 | 2024-11-15 | 주식회사 엘지에너지솔루션 | 비수전해액 및 이를 포함하는 리튬 이차전지 |
| DE102022118867A1 (de) * | 2022-07-27 | 2024-02-01 | Thomas Klose | Gerät und Zusammensetzung zur Behandlung einer Wunde, Kartusche für das Gerät, Verfahren zur Herstellung der Zusammensetzung |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4320140A (en) * | 1980-10-09 | 1982-03-16 | Sterling Drug Inc. | Synergistic insecticidal compositions |
| US4647578A (en) * | 1983-12-02 | 1987-03-03 | Sterling Drug Inc. | Phototoxic insecticidal compositions and method of use thereof |
| AU732936B2 (en) * | 1997-02-03 | 2001-05-03 | Ciba Specialty Chemicals Holding Inc. | Fluorescent materials and their use |
| US8974363B2 (en) * | 1997-12-11 | 2015-03-10 | Provectus Pharmatech, Inc. | Topical medicaments and methods for photodynamic treatment of disease |
| US6676655B2 (en) * | 1998-11-30 | 2004-01-13 | Light Bioscience L.L.C. | Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen |
| CN1372467A (zh) * | 1999-08-13 | 2002-10-02 | 福托金公司 | 改进的局部用药物和疾病的光动力学治疗方法 |
| EP1478713A1 (en) * | 2002-02-01 | 2004-11-24 | Ciba SC Holding AG | Fluorescent compositions comprising diketopyrrolopyrroles |
| US20050059731A1 (en) * | 2003-09-16 | 2005-03-17 | Ceramoptec Industries, Inc. | Erythrosin-based antimicrobial photodynamic therapy compound and its use |
| US7344701B2 (en) * | 2004-02-03 | 2008-03-18 | Biosearch Technologies, Inc. | Xanthene dyes |
| CN101340887B (zh) * | 2005-11-09 | 2014-01-29 | 科洛斯科技公司 | 使牙齿增白的组合物及方法 |
| US20100266989A1 (en) * | 2006-11-09 | 2010-10-21 | Klox Technologies Inc. | Teeth whitening compositions and methods |
| EA029534B1 (ru) * | 2008-11-07 | 2018-04-30 | Клокс Текнолоджиз Инк. | Комбинация оксиданта и фотоактиватора для заживления ран |
| DK2453922T3 (en) * | 2009-07-17 | 2018-01-02 | Klox Tech Inc | ANTIBACTERIAL ORAL COMPOSITION |
| GB201200490D0 (en) * | 2012-01-12 | 2012-02-22 | Univ Bath | Wound dressing |
| WO2014040176A1 (en) * | 2012-09-14 | 2014-03-20 | Klox Technologies Inc. | Chromophore combinations for biophotonic uses |
| US20130281913A1 (en) * | 2012-04-20 | 2013-10-24 | Klox Technologies Inc. | Biophotonic compositions and methods for providing biophotonic treatment |
| US11116841B2 (en) * | 2012-04-20 | 2021-09-14 | Klox Technologies Inc. | Biophotonic compositions, kits and methods |
-
2013
- 2013-09-13 WO PCT/CA2013/000786 patent/WO2014040176A1/en not_active Ceased
- 2013-09-13 KR KR1020187028357A patent/KR20180110240A/ko not_active Ceased
- 2013-09-13 IN IN2938DEN2015 patent/IN2015DN02938A/en unknown
- 2013-09-13 AU AU2013315303A patent/AU2013315303B2/en not_active Ceased
- 2013-09-13 KR KR1020157006411A patent/KR20150068358A/ko not_active Withdrawn
- 2013-09-13 KR KR1020217017420A patent/KR20210072827A/ko not_active Ceased
- 2013-09-13 CN CN201380047508.0A patent/CN104755101B/zh active Active
- 2013-09-13 EP EP13836318.9A patent/EP2895194A4/en not_active Withdrawn
- 2013-09-13 HK HK16100462.1A patent/HK1212592A1/zh unknown
- 2013-09-13 MX MX2015003361A patent/MX367670B/es active IP Right Grant
- 2013-09-13 HK HK15109532.9A patent/HK1208807A1/xx unknown
- 2013-09-13 BR BR112015005382A patent/BR112015005382A2/pt not_active Application Discontinuation
- 2013-09-13 JP JP2015531408A patent/JP2015528472A/ja active Pending
- 2013-09-13 EP EP17196260.8A patent/EP3329938B1/en active Active
- 2013-09-13 RU RU2015113595A patent/RU2015113595A/ru not_active Application Discontinuation
- 2013-09-13 EP EP16184973.2A patent/EP3153177A1/en not_active Withdrawn
-
2015
- 2015-03-10 IL IL237657A patent/IL237657A0/en unknown
- 2015-03-12 ZA ZA2015/01700A patent/ZA201501700B/en unknown
-
2017
- 2017-12-13 JP JP2017238941A patent/JP2018076343A/ja active Pending
-
2018
- 2018-12-19 US US16/225,672 patent/US20190133908A1/en not_active Abandoned
-
2021
- 2021-10-06 JP JP2021164474A patent/JP2022003081A/ja active Pending
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