RU2014130022A - Ингибиторы сиалоадгезина для лечения заболеваний, вызванных вирусами, имеющими оболочку - Google Patents
Ингибиторы сиалоадгезина для лечения заболеваний, вызванных вирусами, имеющими оболочку Download PDFInfo
- Publication number
- RU2014130022A RU2014130022A RU2014130022A RU2014130022A RU2014130022A RU 2014130022 A RU2014130022 A RU 2014130022A RU 2014130022 A RU2014130022 A RU 2014130022A RU 2014130022 A RU2014130022 A RU 2014130022A RU 2014130022 A RU2014130022 A RU 2014130022A
- Authority
- RU
- Russia
- Prior art keywords
- sialyllactose
- antigen
- molecule
- sialoadhesin
- hiv
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16061—Methods of inactivation or attenuation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579242P | 2011-12-22 | 2011-12-22 | |
| EP11382392.6 | 2011-12-22 | ||
| US61/579,242 | 2011-12-22 | ||
| EP11382392.6A EP2606897A1 (en) | 2011-12-22 | 2011-12-22 | Methods and compositions for the treatment of diseases caused by enveloped viruses |
| PCT/EP2012/075831 WO2013092509A1 (en) | 2011-12-22 | 2012-12-17 | Inhibitors of sialoadhesin for the treatment of diseases caused by enveloped viruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2014130022A true RU2014130022A (ru) | 2016-02-10 |
Family
ID=45445920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014130022A RU2014130022A (ru) | 2011-12-22 | 2012-12-17 | Ингибиторы сиалоадгезина для лечения заболеваний, вызванных вирусами, имеющими оболочку |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9789130B2 (enExample) |
| EP (2) | EP2606897A1 (enExample) |
| JP (1) | JP6143781B2 (enExample) |
| KR (1) | KR20140130664A (enExample) |
| CN (1) | CN104168903B (enExample) |
| AU (1) | AU2012357968B2 (enExample) |
| BR (1) | BR112014015112A8 (enExample) |
| CA (1) | CA2858499A1 (enExample) |
| HK (1) | HK1202820A1 (enExample) |
| IL (1) | IL233207A0 (enExample) |
| MX (1) | MX2014007605A (enExample) |
| RU (1) | RU2014130022A (enExample) |
| WO (1) | WO2013092509A1 (enExample) |
| ZA (1) | ZA201403861B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10004695B2 (en) | 2014-04-16 | 2018-06-26 | Trustees Of Boston University | GM3 functionalized nanoparticles |
| CN104587491A (zh) * | 2014-12-30 | 2015-05-06 | 天津大学 | SAMHD1-pLNCX2制备抗肿瘤药物的用途 |
| AU2017261840A1 (en) * | 2016-05-06 | 2018-11-22 | WRS Nutraceuticals Pty Ltd | Agent delivery system |
| CN109906381B (zh) * | 2016-08-31 | 2023-03-31 | 新加坡科技研究局 | 鉴别、靶向以及分离人树突细胞(dc)前体“前dc”的方法及其用途 |
| CN108165559B (zh) * | 2017-11-29 | 2021-06-18 | 昆明理工大学 | 一种c2h2型转录因子基因及其应用 |
| KR20230099676A (ko) * | 2021-12-27 | 2023-07-04 | 주식회사 진켐 | 시알릴락토스를 이용한 혈뇌장벽 투과용 약물 전달체 |
| US20250302865A1 (en) * | 2022-03-16 | 2025-10-02 | Pharmalectin, Inc. | Lectin-binding carbohydrates for treating viral infections |
| KR20240102304A (ko) * | 2022-12-26 | 2024-07-03 | 주식회사 진켐 | 신규한 젬시타빈 결합체 및 이의 용도 |
| CN117886891B (zh) * | 2024-03-15 | 2024-06-07 | 黑龙江八一农垦大学 | 靶向巨噬细胞cd169受体的多肽及其应用 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3916898A (en) | 1964-05-20 | 1975-11-04 | Searle & Co | Administration of medicaments and the like |
| US3888975A (en) | 1972-12-27 | 1975-06-10 | Alza Corp | Erodible intrauterine device |
| US3993754A (en) | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
| US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4086257A (en) | 1976-10-12 | 1978-04-25 | Sears Barry D | Phosphatidyl quaternary ammonium compounds |
| CH624011A5 (enExample) | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| NL7807532A (nl) | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
| FR2433949A1 (fr) | 1978-08-25 | 1980-03-21 | Commissariat Energie Atomique | Substrat hydrophobe apte a liberer une substance chimique |
| US4954487A (en) | 1979-01-08 | 1990-09-04 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| NL8000173A (nl) | 1980-01-11 | 1981-08-03 | Akzo Nv | Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen. |
| US4360013A (en) | 1980-04-21 | 1982-11-23 | Minnesota Mining And Manufacturing Company | Polymeric acid contraceptive devices |
| IT1131833B (it) | 1980-06-20 | 1986-06-25 | Crinos Industria Farmaco | Eccipienti per sostanze spermicide |
| US4389330A (en) | 1980-10-06 | 1983-06-21 | Stolle Research And Development Corporation | Microencapsulation process |
| US4368186A (en) | 1981-05-07 | 1983-01-11 | Syntex (U.S.A.) Inc. | Methods and compositions for intravaginal contraception |
| US4415585A (en) | 1982-03-11 | 1983-11-15 | University Of Illinois Foundation | Contraceptive method |
| US4522803A (en) | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
| US5248700A (en) | 1982-05-14 | 1993-09-28 | Akzo Nv | Active agent containing solid structures for prolonged release of active agents |
| US4961931A (en) | 1982-07-29 | 1990-10-09 | Alza Corporation | Method for the management of hyperplasia |
| US4499154A (en) | 1982-09-03 | 1985-02-12 | Howard L. Podell | Dipped rubber article |
| US4551148A (en) | 1982-09-07 | 1985-11-05 | Kv Pharmaceutical Company | Vaginal delivery systems and their methods of preparation and use |
| US4588578A (en) | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
| US4557934A (en) | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US5231112A (en) | 1984-04-12 | 1993-07-27 | The Liposome Company, Inc. | Compositions containing tris salt of cholesterol hemisuccinate and antifungal |
| US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| JP2754206B2 (ja) * | 1987-11-17 | 1998-05-20 | メクト株式会社 | α2→3結合を認識するモノクローナル抗体 |
| US4999403A (en) | 1988-10-28 | 1991-03-12 | Exxon Chemical Patents Inc. | Graft polymers of functionalized ethylene-alpha-olefin copolymer with polypropylene, methods of preparation, and use in polypropylene compositions |
| US5624824A (en) | 1989-03-24 | 1997-04-29 | Yale University | Targeted cleavage of RNA using eukaryotic ribonuclease P and external guide sequence |
| US5208031A (en) | 1989-06-06 | 1993-05-04 | Kelly Patrick D | Sexual lubricants containing zinc as an anti-viral agent |
| US5286634A (en) | 1989-09-28 | 1994-02-15 | Stadler Joan K | Synergistic method for host cell transformation |
| DE4015543A1 (de) | 1990-05-15 | 1991-11-21 | Bayer Ag | Spermicides beschichtungsmittel |
| DE69119312T2 (de) | 1990-07-18 | 1997-01-16 | Abbott Lab | Analyt-Austauschreagenz zur Verwendung in spezifischen Bindungstests, -vorrichtungen und -sätzen |
| US5143731A (en) | 1990-08-07 | 1992-09-01 | Mediventures Incorporated | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
| FR2666587B1 (fr) | 1990-09-10 | 1993-06-25 | Dow Corning Sa | Compositions de lubrifiant et leur utilisation. |
| GB9021061D0 (en) | 1990-09-27 | 1990-11-07 | Unilever Plc | Encapsulating method and products containing encapsulated material |
| AU687733B2 (en) | 1992-04-01 | 1998-03-05 | Rockefeller University, The | Method for in vitro proliferation of dendritic cell precursors and their use to produce immunogens |
| IL105503A (en) | 1992-04-28 | 1999-05-09 | Astra Ab | Carbon peptide couplets capable of eliciting an immune response of T cells |
| US5976822A (en) | 1995-05-18 | 1999-11-02 | Coulter International Corp. | Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis |
| US5698411A (en) | 1995-05-18 | 1997-12-16 | Coulter Corporation | Method for determining activity of enzymes in metabolically active whole cells |
| US5759781A (en) | 1995-12-22 | 1998-06-02 | Yale University | Multiparametric fluorescence in situ hybridization |
| US6096313A (en) | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US5876935A (en) | 1997-01-08 | 1999-03-02 | Dade Behring Inc. | Luminescent specific binding assay |
| SE9700383D0 (sv) | 1997-02-04 | 1997-02-04 | Pharmacia Biotech Ab | An adsorption/separation method and a medium for adsorption/separation |
| CA2340118C (en) | 1998-08-12 | 2009-01-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal bupivacaine compositions prepared using an ammonium sulfate gradient |
| US6809186B1 (en) | 1999-01-22 | 2004-10-26 | Martek Biosciences Corporation | Simple method for labeled conjugate production |
| EP1168924A4 (en) | 1999-03-31 | 2002-09-04 | Univ Pittsburgh | DERIVATIVED IMMUNOGENES IN VITRO INDUCTION OF ANTIQUE-SPECIFIC T-CELLS USING DENDRITIC CELL-TUMOR CELL OR DENDRITIC CELL-VIRAL CELL |
| US20030092091A1 (en) * | 2000-03-07 | 2003-05-15 | Abrahamson Julie A. | Sialoadhesin factor-2 antibodies |
| MXPA03005373A (es) | 2000-12-13 | 2004-03-26 | Inmunex Corp | Metodo para generar lineas celulares dentriticas inmortales. |
| US8877901B2 (en) | 2002-12-13 | 2014-11-04 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| EP1358910A1 (de) * | 2002-05-02 | 2003-11-05 | B.R.A.H.M.S Aktiengesellschaft | Verfahren und Mittel zur Prävention, Hemmung und Therapie von Krebserkrankungen |
| EP1572242B1 (en) | 2002-12-13 | 2014-04-16 | Immunomedics, Inc. | Immunoconjugates with an intracellularly-cleavable linkage |
| WO2005026322A2 (en) | 2003-09-11 | 2005-03-24 | Clontech Laboratories, Inc. | siRNA ENCODING CONSTRUCTS AND METHODS FOR USING THE SAME |
| WO2005051315A2 (en) | 2003-11-24 | 2005-06-09 | The Regents Of The University Of California | On-demand cleavable linkers for radioconjugates for cancer imaging and therapy |
| US20050266067A1 (en) * | 2004-03-02 | 2005-12-01 | Shiladitya Sengupta | Nanocell drug delivery system |
| CN101484182B (zh) | 2005-04-06 | 2014-06-11 | Ibc药品公司 | 由同二聚体、同四聚体或二聚体的二聚体组成的稳定连接复合体的生产方法及用途 |
| JP5231231B2 (ja) | 2005-10-19 | 2013-07-10 | アイビーシー・ファーマシューティカルズ・インコーポレーテッド | 複雑性が増大した生理活性アセンブリーを生成するための方法および組成物ならびに使用 |
| EP2060257A1 (en) * | 2007-11-08 | 2009-05-20 | Nestec S.A. | Prevention and treatment of secondary infections following viral infection |
| US8591905B2 (en) * | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
| JP5641598B2 (ja) * | 2009-09-29 | 2014-12-17 | 雪印メグミルク株式会社 | シアリルラクトース素材の分離方法 |
| JP5788653B2 (ja) * | 2010-09-10 | 2015-10-07 | 靖人 江原 | 糖鎖修飾ヌクレオチド及びその使用 |
-
2011
- 2011-12-22 EP EP11382392.6A patent/EP2606897A1/en not_active Withdrawn
-
2012
- 2012-12-17 CN CN201280063973.9A patent/CN104168903B/zh not_active Expired - Fee Related
- 2012-12-17 AU AU2012357968A patent/AU2012357968B2/en not_active Ceased
- 2012-12-17 CA CA2858499A patent/CA2858499A1/en not_active Abandoned
- 2012-12-17 BR BR112014015112A patent/BR112014015112A8/pt not_active Application Discontinuation
- 2012-12-17 US US14/366,839 patent/US9789130B2/en not_active Expired - Fee Related
- 2012-12-17 HK HK15103563.4A patent/HK1202820A1/xx unknown
- 2012-12-17 EP EP12806031.6A patent/EP2793904A1/en not_active Withdrawn
- 2012-12-17 JP JP2014547900A patent/JP6143781B2/ja not_active Expired - Fee Related
- 2012-12-17 RU RU2014130022A patent/RU2014130022A/ru not_active Application Discontinuation
- 2012-12-17 WO PCT/EP2012/075831 patent/WO2013092509A1/en not_active Ceased
- 2012-12-17 MX MX2014007605A patent/MX2014007605A/es unknown
- 2012-12-17 KR KR20147019234A patent/KR20140130664A/ko not_active Withdrawn
-
2014
- 2014-05-27 ZA ZA2014/03861A patent/ZA201403861B/en unknown
- 2014-06-17 IL IL233207A patent/IL233207A0/en unknown
Also Published As
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|---|---|
| AU2012357968B2 (en) | 2017-10-05 |
| MX2014007605A (es) | 2015-07-06 |
| US20140370052A1 (en) | 2014-12-18 |
| CA2858499A1 (en) | 2013-06-27 |
| EP2606897A1 (en) | 2013-06-26 |
| US9789130B2 (en) | 2017-10-17 |
| EP2793904A1 (en) | 2014-10-29 |
| IL233207A0 (en) | 2014-07-31 |
| JP6143781B2 (ja) | 2017-06-07 |
| JP2015500854A (ja) | 2015-01-08 |
| CN104168903B (zh) | 2017-05-31 |
| HK1202820A1 (en) | 2015-10-09 |
| CN104168903A (zh) | 2014-11-26 |
| BR112014015112A2 (pt) | 2017-06-13 |
| WO2013092509A1 (en) | 2013-06-27 |
| NZ627650A (en) | 2016-01-29 |
| KR20140130664A (ko) | 2014-11-11 |
| BR112014015112A8 (pt) | 2017-06-13 |
| AU2012357968A1 (en) | 2014-08-14 |
| ZA201403861B (en) | 2015-09-30 |
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| HZ9A | Changing address for correspondence with an applicant | ||
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20191018 |