JP2015500854A5 - - Google Patents
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- Publication number
- JP2015500854A5 JP2015500854A5 JP2014547900A JP2014547900A JP2015500854A5 JP 2015500854 A5 JP2015500854 A5 JP 2015500854A5 JP 2014547900 A JP2014547900 A JP 2014547900A JP 2014547900 A JP2014547900 A JP 2014547900A JP 2015500854 A5 JP2015500854 A5 JP 2015500854A5
- Authority
- JP
- Japan
- Prior art keywords
- sialoadhesin
- inhibitor
- antigen
- hiv
- sialyl lactose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000001558 Sialic Acid Binding Ig-like Lectin 1 Human genes 0.000 claims 18
- 108010029176 Sialic Acid Binding Ig-like Lectin 1 Proteins 0.000 claims 18
- 239000003112 inhibitor Substances 0.000 claims 18
- OIZGSVFYNBZVIK-FHHHURIISA-N 3'-sialyllactose Chemical compound O1[C@@H]([C@H](O)[C@H](O)CO)[C@H](NC(=O)C)[C@@H](O)C[C@@]1(C(O)=O)O[C@@H]1[C@@H](O)[C@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O[C@H](CO)[C@@H]1O OIZGSVFYNBZVIK-FHHHURIISA-N 0.000 claims 13
- 238000000034 method Methods 0.000 claims 13
- 241000700605 Viruses Species 0.000 claims 11
- 241000725303 Human immunodeficiency virus Species 0.000 claims 10
- 239000000427 antigen Substances 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 7
- 241001430294 unidentified retrovirus Species 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 150000002632 lipids Chemical class 0.000 claims 4
- 241000711950 Filoviridae Species 0.000 claims 3
- 241000713772 Human immunodeficiency virus 1 Species 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 125000002421 ganglioside group Chemical group 0.000 claims 3
- 125000005629 sialic acid group Chemical group 0.000 claims 3
- 208000030507 AIDS Diseases 0.000 claims 2
- 210000004443 dendritic cell Anatomy 0.000 claims 2
- 239000000032 diagnostic agent Substances 0.000 claims 2
- 229940039227 diagnostic agent Drugs 0.000 claims 2
- 230000006806 disease prevention Effects 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 102000053642 Catalytic RNA Human genes 0.000 claims 1
- 108090000994 Catalytic RNA Proteins 0.000 claims 1
- 208000031886 HIV Infections Diseases 0.000 claims 1
- 208000037357 HIV infectious disease Diseases 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 108010003533 Viral Envelope Proteins Proteins 0.000 claims 1
- 239000002259 anti human immunodeficiency virus agent Substances 0.000 claims 1
- 229940124411 anti-hiv antiviral agent Drugs 0.000 claims 1
- 229940124522 antiretrovirals Drugs 0.000 claims 1
- 239000003903 antiretrovirus agent Substances 0.000 claims 1
- 239000000074 antisense oligonucleotide Substances 0.000 claims 1
- 238000012230 antisense oligonucleotides Methods 0.000 claims 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 108091092562 ribozyme Proteins 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579242P | 2011-12-22 | 2011-12-22 | |
| EP11382392.6 | 2011-12-22 | ||
| US61/579,242 | 2011-12-22 | ||
| EP11382392.6A EP2606897A1 (en) | 2011-12-22 | 2011-12-22 | Methods and compositions for the treatment of diseases caused by enveloped viruses |
| PCT/EP2012/075831 WO2013092509A1 (en) | 2011-12-22 | 2012-12-17 | Inhibitors of sialoadhesin for the treatment of diseases caused by enveloped viruses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015500854A JP2015500854A (ja) | 2015-01-08 |
| JP2015500854A5 true JP2015500854A5 (enExample) | 2016-03-17 |
| JP6143781B2 JP6143781B2 (ja) | 2017-06-07 |
Family
ID=45445920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547900A Expired - Fee Related JP6143781B2 (ja) | 2011-12-22 | 2012-12-17 | エンベロープウイルスにより引き起こされる疾病を治療するための方法および組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9789130B2 (enExample) |
| EP (2) | EP2606897A1 (enExample) |
| JP (1) | JP6143781B2 (enExample) |
| KR (1) | KR20140130664A (enExample) |
| CN (1) | CN104168903B (enExample) |
| AU (1) | AU2012357968B2 (enExample) |
| BR (1) | BR112014015112A8 (enExample) |
| CA (1) | CA2858499A1 (enExample) |
| HK (1) | HK1202820A1 (enExample) |
| IL (1) | IL233207A0 (enExample) |
| MX (1) | MX2014007605A (enExample) |
| RU (1) | RU2014130022A (enExample) |
| WO (1) | WO2013092509A1 (enExample) |
| ZA (1) | ZA201403861B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10004695B2 (en) | 2014-04-16 | 2018-06-26 | Trustees Of Boston University | GM3 functionalized nanoparticles |
| CN104587491A (zh) * | 2014-12-30 | 2015-05-06 | 天津大学 | SAMHD1-pLNCX2制备抗肿瘤药物的用途 |
| AU2017261840A1 (en) * | 2016-05-06 | 2018-11-22 | WRS Nutraceuticals Pty Ltd | Agent delivery system |
| CN109906381B (zh) * | 2016-08-31 | 2023-03-31 | 新加坡科技研究局 | 鉴别、靶向以及分离人树突细胞(dc)前体“前dc”的方法及其用途 |
| CN108165559B (zh) * | 2017-11-29 | 2021-06-18 | 昆明理工大学 | 一种c2h2型转录因子基因及其应用 |
| KR20230099676A (ko) * | 2021-12-27 | 2023-07-04 | 주식회사 진켐 | 시알릴락토스를 이용한 혈뇌장벽 투과용 약물 전달체 |
| US20250302865A1 (en) * | 2022-03-16 | 2025-10-02 | Pharmalectin, Inc. | Lectin-binding carbohydrates for treating viral infections |
| KR20240102304A (ko) * | 2022-12-26 | 2024-07-03 | 주식회사 진켐 | 신규한 젬시타빈 결합체 및 이의 용도 |
| CN117886891B (zh) * | 2024-03-15 | 2024-06-07 | 黑龙江八一农垦大学 | 靶向巨噬细胞cd169受体的多肽及其应用 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3916898A (en) | 1964-05-20 | 1975-11-04 | Searle & Co | Administration of medicaments and the like |
| US3888975A (en) | 1972-12-27 | 1975-06-10 | Alza Corp | Erodible intrauterine device |
| US3993754A (en) | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
| US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4086257A (en) | 1976-10-12 | 1978-04-25 | Sears Barry D | Phosphatidyl quaternary ammonium compounds |
| CH624011A5 (enExample) | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| NL7807532A (nl) | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
| FR2433949A1 (fr) | 1978-08-25 | 1980-03-21 | Commissariat Energie Atomique | Substrat hydrophobe apte a liberer une substance chimique |
| US4954487A (en) | 1979-01-08 | 1990-09-04 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| NL8000173A (nl) | 1980-01-11 | 1981-08-03 | Akzo Nv | Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen. |
| US4360013A (en) | 1980-04-21 | 1982-11-23 | Minnesota Mining And Manufacturing Company | Polymeric acid contraceptive devices |
| IT1131833B (it) | 1980-06-20 | 1986-06-25 | Crinos Industria Farmaco | Eccipienti per sostanze spermicide |
| US4389330A (en) | 1980-10-06 | 1983-06-21 | Stolle Research And Development Corporation | Microencapsulation process |
| US4368186A (en) | 1981-05-07 | 1983-01-11 | Syntex (U.S.A.) Inc. | Methods and compositions for intravaginal contraception |
| US4415585A (en) | 1982-03-11 | 1983-11-15 | University Of Illinois Foundation | Contraceptive method |
| US4522803A (en) | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
| US5248700A (en) | 1982-05-14 | 1993-09-28 | Akzo Nv | Active agent containing solid structures for prolonged release of active agents |
| US4961931A (en) | 1982-07-29 | 1990-10-09 | Alza Corporation | Method for the management of hyperplasia |
| US4499154A (en) | 1982-09-03 | 1985-02-12 | Howard L. Podell | Dipped rubber article |
| US4551148A (en) | 1982-09-07 | 1985-11-05 | Kv Pharmaceutical Company | Vaginal delivery systems and their methods of preparation and use |
| US4588578A (en) | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
| US4557934A (en) | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US5231112A (en) | 1984-04-12 | 1993-07-27 | The Liposome Company, Inc. | Compositions containing tris salt of cholesterol hemisuccinate and antifungal |
| US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| JP2754206B2 (ja) * | 1987-11-17 | 1998-05-20 | メクト株式会社 | α２→３結合を認識するモノクローナル抗体 |
| US4999403A (en) | 1988-10-28 | 1991-03-12 | Exxon Chemical Patents Inc. | Graft polymers of functionalized ethylene-alpha-olefin copolymer with polypropylene, methods of preparation, and use in polypropylene compositions |
| US5624824A (en) | 1989-03-24 | 1997-04-29 | Yale University | Targeted cleavage of RNA using eukaryotic ribonuclease P and external guide sequence |
| US5208031A (en) | 1989-06-06 | 1993-05-04 | Kelly Patrick D | Sexual lubricants containing zinc as an anti-viral agent |
| US5286634A (en) | 1989-09-28 | 1994-02-15 | Stadler Joan K | Synergistic method for host cell transformation |
| DE4015543A1 (de) | 1990-05-15 | 1991-11-21 | Bayer Ag | Spermicides beschichtungsmittel |
| DE69119312T2 (de) | 1990-07-18 | 1997-01-16 | Abbott Lab | Analyt-Austauschreagenz zur Verwendung in spezifischen Bindungstests, -vorrichtungen und -sätzen |
| US5143731A (en) | 1990-08-07 | 1992-09-01 | Mediventures Incorporated | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
| FR2666587B1 (fr) | 1990-09-10 | 1993-06-25 | Dow Corning Sa | Compositions de lubrifiant et leur utilisation. |
| GB9021061D0 (en) | 1990-09-27 | 1990-11-07 | Unilever Plc | Encapsulating method and products containing encapsulated material |
| AU687733B2 (en) | 1992-04-01 | 1998-03-05 | Rockefeller University, The | Method for in vitro proliferation of dendritic cell precursors and their use to produce immunogens |
| IL105503A (en) | 1992-04-28 | 1999-05-09 | Astra Ab | Carbon peptide couplets capable of eliciting an immune response of T cells |
| US5976822A (en) | 1995-05-18 | 1999-11-02 | Coulter International Corp. | Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis |
| US5698411A (en) | 1995-05-18 | 1997-12-16 | Coulter Corporation | Method for determining activity of enzymes in metabolically active whole cells |
| US5759781A (en) | 1995-12-22 | 1998-06-02 | Yale University | Multiparametric fluorescence in situ hybridization |
| US6096313A (en) | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US5876935A (en) | 1997-01-08 | 1999-03-02 | Dade Behring Inc. | Luminescent specific binding assay |
| SE9700383D0 (sv) | 1997-02-04 | 1997-02-04 | Pharmacia Biotech Ab | An adsorption/separation method and a medium for adsorption/separation |
| CA2340118C (en) | 1998-08-12 | 2009-01-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal bupivacaine compositions prepared using an ammonium sulfate gradient |
| US6809186B1 (en) | 1999-01-22 | 2004-10-26 | Martek Biosciences Corporation | Simple method for labeled conjugate production |
| EP1168924A4 (en) | 1999-03-31 | 2002-09-04 | Univ Pittsburgh | DERIVATIVED IMMUNOGENES IN VITRO INDUCTION OF ANTIQUE-SPECIFIC T-CELLS USING DENDRITIC CELL-TUMOR CELL OR DENDRITIC CELL-VIRAL CELL |
| US20030092091A1 (en) * | 2000-03-07 | 2003-05-15 | Abrahamson Julie A. | Sialoadhesin factor-2 antibodies |
| MXPA03005373A (es) | 2000-12-13 | 2004-03-26 | Inmunex Corp | Metodo para generar lineas celulares dentriticas inmortales. |
| US8877901B2 (en) | 2002-12-13 | 2014-11-04 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| EP1358910A1 (de) * | 2002-05-02 | 2003-11-05 | B.R.A.H.M.S Aktiengesellschaft | Verfahren und Mittel zur Prävention, Hemmung und Therapie von Krebserkrankungen |
| EP1572242B1 (en) | 2002-12-13 | 2014-04-16 | Immunomedics, Inc. | Immunoconjugates with an intracellularly-cleavable linkage |
| WO2005026322A2 (en) | 2003-09-11 | 2005-03-24 | Clontech Laboratories, Inc. | siRNA ENCODING CONSTRUCTS AND METHODS FOR USING THE SAME |
| WO2005051315A2 (en) | 2003-11-24 | 2005-06-09 | The Regents Of The University Of California | On-demand cleavable linkers for radioconjugates for cancer imaging and therapy |
| US20050266067A1 (en) * | 2004-03-02 | 2005-12-01 | Shiladitya Sengupta | Nanocell drug delivery system |
| CN101484182B (zh) | 2005-04-06 | 2014-06-11 | Ibc药品公司 | 由同二聚体、同四聚体或二聚体的二聚体组成的稳定连接复合体的生产方法及用途 |
| JP5231231B2 (ja) | 2005-10-19 | 2013-07-10 | アイビーシー・ファーマシューティカルズ・インコーポレーテッド | 複雑性が増大した生理活性アセンブリーを生成するための方法および組成物ならびに使用 |
| EP2060257A1 (en) * | 2007-11-08 | 2009-05-20 | Nestec S.A. | Prevention and treatment of secondary infections following viral infection |
| US8591905B2 (en) * | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
| JP5641598B2 (ja) * | 2009-09-29 | 2014-12-17 | 雪印メグミルク株式会社 | シアリルラクトース素材の分離方法 |
| JP5788653B2 (ja) * | 2010-09-10 | 2015-10-07 | 靖人 江原 | 糖鎖修飾ヌクレオチド及びその使用 |
-
2011
- 2011-12-22 EP EP11382392.6A patent/EP2606897A1/en not_active Withdrawn
-
2012
- 2012-12-17 CN CN201280063973.9A patent/CN104168903B/zh not_active Expired - Fee Related
- 2012-12-17 AU AU2012357968A patent/AU2012357968B2/en not_active Ceased
- 2012-12-17 CA CA2858499A patent/CA2858499A1/en not_active Abandoned
- 2012-12-17 BR BR112014015112A patent/BR112014015112A8/pt not_active Application Discontinuation
- 2012-12-17 US US14/366,839 patent/US9789130B2/en not_active Expired - Fee Related
- 2012-12-17 HK HK15103563.4A patent/HK1202820A1/xx unknown
- 2012-12-17 EP EP12806031.6A patent/EP2793904A1/en not_active Withdrawn
- 2012-12-17 JP JP2014547900A patent/JP6143781B2/ja not_active Expired - Fee Related
- 2012-12-17 RU RU2014130022A patent/RU2014130022A/ru not_active Application Discontinuation
- 2012-12-17 WO PCT/EP2012/075831 patent/WO2013092509A1/en not_active Ceased
- 2012-12-17 MX MX2014007605A patent/MX2014007605A/es unknown
- 2012-12-17 KR KR20147019234A patent/KR20140130664A/ko not_active Withdrawn
-
2014
- 2014-05-27 ZA ZA2014/03861A patent/ZA201403861B/en unknown
- 2014-06-17 IL IL233207A patent/IL233207A0/en unknown
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