RU2014129813A - Композиции для ухода за полостью рта - Google Patents
Композиции для ухода за полостью рта Download PDFInfo
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- RU2014129813A RU2014129813A RU2014129813A RU2014129813A RU2014129813A RU 2014129813 A RU2014129813 A RU 2014129813A RU 2014129813 A RU2014129813 A RU 2014129813A RU 2014129813 A RU2014129813 A RU 2014129813A RU 2014129813 A RU2014129813 A RU 2014129813A
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- cationic steroid
- quaternary ammonium
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- 0 C[C@](CCC*)[C@@](CC[C@]1C([C@](C2)[C@@](C)(CC[C@](C3)OCCCN)C3C3)[C@@]3OCCC*)[C@@]1(C)[C@]2OCCCN Chemical compound C[C@](CCC*)[C@@](CC[C@]1C([C@](C2)[C@@](C)(CC[C@](C3)OCCCN)C3C3)[C@@]3OCCC*)[C@@]1(C)[C@]2OCCCN 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
1. Водная композиция для ухода за полостью рта, содержащая:катионное стероидное соединение ичетвертичное аммониевое соединение.2. Композиция по п. 1, где композиция представляет собой жидкость для полоскания рта.3. Композиция по п. 1 или 2, где катионное стероидное соединение представляет собой соединение формулы (I):,где Rвыбран из -ОН и NH-R, где Rозначает С-Салкил, С-Салкенил или С-Салкинил, и n равно 3 или 4.4. Композиция по п. 3, где соединение формулы (I) выбрано из соединения формулы (II):исоединения формулы (III):.5. Композиция по п. 1 или 2, где катионное стероидное соединение представляет собой соединение формулы (II):.6. Композиция по п. 1 или 2, где четвертичное аммониевое соединение выбрано из: бензалконийхлорида, бензетонийхлорида, метилбензетонийхлорида, цеталконийхлорида, цетилпиридинийхлорида, цетримония, цетримида, дофанийхлорида, тетраэтиламмонийбромида, дидецилдиметиламмонийхлорида и домифенбромида.7. Композиция по п 1. или 2, где четвертичное аммониевое соединение включает цетилпиридинийхлорид.8. Композиция по п. 1 или 2, где катионное стероидное соединение присутствует в концентрации приблизительно от 0,01% до приблизительно 0,1% масс. композиции.9. Композиция по п. 1 или 2, где четвертичное аммониевое соединение присутствует в концентрации приблизительно от 0,01% до приблизительно 0,1% масс. композиции.10. Композиция по п. 1 или 2, где катионное стероидное соединение и четвертичное аммониевое соединение присутствует в соотношении 1:1 на основе их соответствующих концентраций по массе композиции.11. Композиция по п. 1 или 2, где катионное стероидное соединение присутствует в концентрации приблизительно 0,05% масс. композиции.12. Композиция по п. 1 или 2, где четвертичное аммониевое соединение присутству
Claims (20)
1. Водная композиция для ухода за полостью рта, содержащая:
катионное стероидное соединение и
четвертичное аммониевое соединение.
2. Композиция по п. 1, где композиция представляет собой жидкость для полоскания рта.
6. Композиция по п. 1 или 2, где четвертичное аммониевое соединение выбрано из: бензалконийхлорида, бензетонийхлорида, метилбензетонийхлорида, цеталконийхлорида, цетилпиридинийхлорида, цетримония, цетримида, дофанийхлорида, тетраэтиламмонийбромида, дидецилдиметиламмонийхлорида и домифенбромида.
7. Композиция по п 1. или 2, где четвертичное аммониевое соединение включает цетилпиридинийхлорид.
8. Композиция по п. 1 или 2, где катионное стероидное соединение присутствует в концентрации приблизительно от 0,01% до приблизительно 0,1% масс. композиции.
9. Композиция по п. 1 или 2, где четвертичное аммониевое соединение присутствует в концентрации приблизительно от 0,01% до приблизительно 0,1% масс. композиции.
10. Композиция по п. 1 или 2, где катионное стероидное соединение и четвертичное аммониевое соединение присутствует в соотношении 1:1 на основе их соответствующих концентраций по массе композиции.
11. Композиция по п. 1 или 2, где катионное стероидное соединение присутствует в концентрации приблизительно 0,05% масс. композиции.
12. Композиция по п. 1 или 2, где четвертичное аммониевое соединение присутствует в концентрации приблизительно 0,05% масс. композиции.
13. Композиция по п. 1 или 2, дополнительно содержащая источник фторидного иона, где источник фторидного иона выбран из фторида олова(II), фторида натрия, фторида калия, монофторфосфата натрия, фторсиликата натрия, фторсиликата аммония, фторида амина, фторида аммония и комбинации двух или более данных компонентов.
14. Композиция по п. 13, где источник фторидного иона состоит из фторида натрия.
15. Способ лечения заболевания или состояния полости рта, включающий введение композиции по п. 1 или 2 в полость рта субъекта, нуждающегося в этом.
16. Способ лечения воспалительного состояния полости рта, включающий введение композиции, содержащей катионное стероидное соединение, в полость рта субъекта, нуждающегося в этом.
17. Способ снижения летучих соединений серы, включающий введение композиции, содержащей катионное стероидное соединение, в полость рта субъекта, нуждающегося в этом.
18. Композиция по п. 1или 2 для применения при лечении заболевания или состояния полости рта.
19. Композиция, содержащая катионное стероидное соединение, для применения в способе лечения воспалительного состояния полости рта, причем способ включает введение композиции в полость рта субъекта.
20. Композиция, содержащая катионное стероидное соединение, для применения в способе снижения летучих соединений серы, причем способ включает введение композиции в полость рта субъекта.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2011/066482 WO2013109236A2 (en) | 2011-12-21 | 2011-12-21 | Oral care compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2014129813A true RU2014129813A (ru) | 2016-02-10 |
RU2625838C2 RU2625838C2 (ru) | 2017-07-19 |
Family
ID=48326382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2014129813A RU2625838C2 (ru) | 2011-12-21 | 2011-12-21 | Композиции для ухода за полостью рта |
Country Status (16)
Country | Link |
---|---|
US (2) | US9345655B2 (ru) |
EP (2) | EP3449900A1 (ru) |
JP (1) | JP6051230B2 (ru) |
KR (1) | KR20140116111A (ru) |
CN (1) | CN104379120A (ru) |
AR (1) | AR089372A1 (ru) |
AU (1) | AU2011385377B2 (ru) |
BR (1) | BR112014015144B1 (ru) |
CA (1) | CA2859325A1 (ru) |
IL (1) | IL233216A0 (ru) |
MX (1) | MX2014007496A (ru) |
NZ (1) | NZ626144A (ru) |
RU (1) | RU2625838C2 (ru) |
TW (1) | TWI559936B (ru) |
UA (1) | UA113298C2 (ru) |
WO (1) | WO2013109236A2 (ru) |
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US11690855B2 (en) | 2013-10-17 | 2023-07-04 | Brigham Young University | Methods for treating lung infections and inflammation |
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-
2011
- 2011-12-21 UA UAA201408158A patent/UA113298C2/uk unknown
- 2011-12-21 CA CA2859325A patent/CA2859325A1/en not_active Abandoned
- 2011-12-21 AU AU2011385377A patent/AU2011385377B2/en not_active Ceased
- 2011-12-21 WO PCT/US2011/066482 patent/WO2013109236A2/en active Application Filing
- 2011-12-21 NZ NZ626144A patent/NZ626144A/en not_active IP Right Cessation
- 2011-12-21 EP EP18167462.3A patent/EP3449900A1/en not_active Withdrawn
- 2011-12-21 MX MX2014007496A patent/MX2014007496A/es unknown
- 2011-12-21 BR BR112014015144-0A patent/BR112014015144B1/pt not_active IP Right Cessation
- 2011-12-21 US US14/364,283 patent/US9345655B2/en active Active
- 2011-12-21 CN CN201180075880.3A patent/CN104379120A/zh active Pending
- 2011-12-21 EP EP11875594.1A patent/EP2793832B1/en not_active Not-in-force
- 2011-12-21 JP JP2014548757A patent/JP6051230B2/ja not_active Expired - Fee Related
- 2011-12-21 RU RU2014129813A patent/RU2625838C2/ru not_active IP Right Cessation
- 2011-12-21 KR KR1020147019874A patent/KR20140116111A/ko not_active Application Discontinuation
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2012
- 2012-12-20 AR ARP120104872A patent/AR089372A1/es unknown
- 2012-12-20 TW TW101148570A patent/TWI559936B/zh not_active IP Right Cessation
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2014
- 2014-06-18 IL IL233216A patent/IL233216A0/en unknown
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IL233216A0 (en) | 2014-08-31 |
JP6051230B2 (ja) | 2016-12-27 |
AU2011385377A1 (en) | 2014-07-03 |
TWI559936B (en) | 2016-12-01 |
EP3449900A1 (en) | 2019-03-06 |
EP2793832B1 (en) | 2018-05-23 |
US20160045421A1 (en) | 2016-02-18 |
US9345655B2 (en) | 2016-05-24 |
JP2015502978A (ja) | 2015-01-29 |
CN104379120A (zh) | 2015-02-25 |
MX2014007496A (es) | 2015-02-17 |
CA2859325A1 (en) | 2013-07-25 |
BR112014015144A2 (pt) | 2017-06-13 |
AR089372A1 (es) | 2014-08-20 |
KR20140116111A (ko) | 2014-10-01 |
NZ626144A (en) | 2016-05-27 |
UA113298C2 (xx) | 2017-01-10 |
US20140369941A1 (en) | 2014-12-18 |
TW201332581A (zh) | 2013-08-16 |
WO2013109236A2 (en) | 2013-07-25 |
BR112014015144B1 (pt) | 2018-03-27 |
RU2625838C2 (ru) | 2017-07-19 |
AU2011385377B2 (en) | 2017-06-01 |
EP2793832A2 (en) | 2014-10-29 |
WO2013109236A3 (en) | 2013-10-10 |
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