RU2013157923A - Терапия на основе модулирования иммунодоминантности - Google Patents
Терапия на основе модулирования иммунодоминантности Download PDFInfo
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- RU2013157923A RU2013157923A RU2013157923/10A RU2013157923A RU2013157923A RU 2013157923 A RU2013157923 A RU 2013157923A RU 2013157923/10 A RU2013157923/10 A RU 2013157923/10A RU 2013157923 A RU2013157923 A RU 2013157923A RU 2013157923 A RU2013157923 A RU 2013157923A
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- Prior art keywords
- patient
- epitope
- antigen
- cell
- cells
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- 238000002560 therapeutic procedure Methods 0.000 title claims 3
- 210000001744 T-lymphocyte Anatomy 0.000 claims abstract 35
- 239000000427 antigen Substances 0.000 claims abstract 29
- 102000036639 antigens Human genes 0.000 claims abstract 29
- 108091007433 antigens Proteins 0.000 claims abstract 29
- 238000000034 method Methods 0.000 claims abstract 13
- 238000012258 culturing Methods 0.000 claims abstract 9
- 206010061218 Inflammation Diseases 0.000 claims abstract 6
- 206010028980 Neoplasm Diseases 0.000 claims abstract 6
- 230000004054 inflammatory process Effects 0.000 claims abstract 6
- 210000000056 organ Anatomy 0.000 claims abstract 6
- 201000011510 cancer Diseases 0.000 claims abstract 5
- 208000015181 infectious disease Diseases 0.000 claims abstract 5
- 239000003814 drug Substances 0.000 claims abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 230000024932 T cell mediated immunity Effects 0.000 claims 2
- 230000007815 allergy Effects 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000028996 humoral immune response Effects 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 206010052779 Transplant rejections Diseases 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- 231100000433 cytotoxic Toxicity 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 208000024908 graft versus host disease Diseases 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
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- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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| NZ749136A (en) | 2016-05-25 | 2023-11-24 | Council Queensland Inst Medical Res | Methods of immunotherapy |
| AU2017283480A1 (en) | 2016-06-13 | 2019-01-24 | Torque Therapeutics, Inc. | Methods and compositions for promoting immune cell function |
| JP7034955B2 (ja) * | 2016-06-28 | 2022-03-14 | ジーニアス・バイオテクノロジー・インコーポレイテッド | 免疫療法向けのt細胞組成物 |
| EP3678701A4 (en) | 2017-09-05 | 2021-12-01 | Torque Therapeutics, Inc. | THERAPEUTIC PROTEIN COMPOSITIONS AND METHODS FOR PREPARING AND USING THE SAME |
| EP3700553A1 (en) | 2017-10-23 | 2020-09-02 | Atara Biotherapeutics, Inc. | Methods of managing tumor flare in adoptive immunotherapy |
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| JP2001509677A (ja) * | 1997-01-31 | 2001-07-24 | エピミューン,インコーポレイティド | Ctlを活性化するためのペプチドおよびペプチド担持抗原提示細胞 |
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2016
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2019
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| WO2012162620A1 (en) | 2012-11-29 |
| US20170101625A1 (en) | 2017-04-13 |
| US20170043000A1 (en) | 2017-02-16 |
| US20170042999A1 (en) | 2017-02-16 |
| US20240189353A1 (en) | 2024-06-13 |
| KR20160104753A (ko) | 2016-09-05 |
| HK1199404A1 (en) | 2015-07-03 |
| JP2014516538A (ja) | 2014-07-17 |
| AU2021200831A1 (en) | 2021-03-04 |
| KR20140068810A (ko) | 2014-06-09 |
| SG10201604236RA (en) | 2016-07-28 |
| CN111529697A (zh) | 2020-08-14 |
| US11723921B2 (en) | 2023-08-15 |
| TWI774957B (zh) | 2022-08-21 |
| AU2019201456A1 (en) | 2019-03-21 |
| TW202321442A (zh) | 2023-06-01 |
| US20170043001A1 (en) | 2017-02-16 |
| US20140099341A1 (en) | 2014-04-10 |
| TW201313902A (zh) | 2013-04-01 |
| TW201934749A (zh) | 2019-09-01 |
| EP2714072A1 (en) | 2014-04-09 |
| AU2012258603A1 (en) | 2014-01-16 |
| CA2874431A1 (en) | 2012-11-29 |
| US20170042998A1 (en) | 2017-02-16 |
| US20170216357A1 (en) | 2017-08-03 |
| AU2017203671A1 (en) | 2017-06-15 |
| CN103906531A (zh) | 2014-07-02 |
| EP4285922A1 (en) | 2023-12-06 |
| SG10202012534VA (en) | 2021-01-28 |
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