RU2013147265A - РЕГЕНЕРАЦИЯ КОСТЕЙ И ХРЯЩЕЙ С ПОМОЩЬЮ АУТОЛОГИЧНЫХ ПЛЮРИПОТЕНТНЫХ ОЧЕНЬ МАЛЕНЬКИХ ЭМБРИОНОПОДОБНЫХ (hVSEL) СТВОЛОВЫХ КЛЕТОК ВЗРОСЛЫХ ЛЮДЕЙ - Google Patents

РЕГЕНЕРАЦИЯ КОСТЕЙ И ХРЯЩЕЙ С ПОМОЩЬЮ АУТОЛОГИЧНЫХ ПЛЮРИПОТЕНТНЫХ ОЧЕНЬ МАЛЕНЬКИХ ЭМБРИОНОПОДОБНЫХ (hVSEL) СТВОЛОВЫХ КЛЕТОК ВЗРОСЛЫХ ЛЮДЕЙ Download PDF

Info

Publication number
RU2013147265A
RU2013147265A RU2013147265/10A RU2013147265A RU2013147265A RU 2013147265 A RU2013147265 A RU 2013147265A RU 2013147265/10 A RU2013147265/10 A RU 2013147265/10A RU 2013147265 A RU2013147265 A RU 2013147265A RU 2013147265 A RU2013147265 A RU 2013147265A
Authority
RU
Russia
Prior art keywords
cells
vsel
composition
per
composition comprises
Prior art date
Application number
RU2013147265/10A
Other languages
English (en)
Russian (ru)
Inventor
Рассел ТАЙЧМАН
Пол Х. КРЕБСБАХ
Аарон ХЕЙВЕНС
Анджали МИШРА
Денис О. РОДЖЕРСОН
Чинчхен ВАН
Юсукэ СИОДЗАВА
Йонхон ЧОН
Original Assignee
Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган
Неостем, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган, Неостем, Инк. filed Critical Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган
Publication of RU2013147265A publication Critical patent/RU2013147265A/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Botany (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
RU2013147265/10A 2011-04-08 2012-04-09 РЕГЕНЕРАЦИЯ КОСТЕЙ И ХРЯЩЕЙ С ПОМОЩЬЮ АУТОЛОГИЧНЫХ ПЛЮРИПОТЕНТНЫХ ОЧЕНЬ МАЛЕНЬКИХ ЭМБРИОНОПОДОБНЫХ (hVSEL) СТВОЛОВЫХ КЛЕТОК ВЗРОСЛЫХ ЛЮДЕЙ RU2013147265A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161473420P 2011-04-08 2011-04-08
US61/473,420 2011-04-08
PCT/US2012/032807 WO2012139131A1 (en) 2011-04-08 2012-04-09 Autologous human adult pluripotent very small embryonic-like (hvsel) stem cell regeneration of bone and cartilage

Publications (1)

Publication Number Publication Date
RU2013147265A true RU2013147265A (ru) 2015-05-20

Family

ID=46969593

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2013147265/10A RU2013147265A (ru) 2011-04-08 2012-04-09 РЕГЕНЕРАЦИЯ КОСТЕЙ И ХРЯЩЕЙ С ПОМОЩЬЮ АУТОЛОГИЧНЫХ ПЛЮРИПОТЕНТНЫХ ОЧЕНЬ МАЛЕНЬКИХ ЭМБРИОНОПОДОБНЫХ (hVSEL) СТВОЛОВЫХ КЛЕТОК ВЗРОСЛЫХ ЛЮДЕЙ

Country Status (9)

Country Link
US (1) US20140112891A1 (cg-RX-API-DMAC7.html)
EP (1) EP2694641A4 (cg-RX-API-DMAC7.html)
JP (1) JP2014511864A (cg-RX-API-DMAC7.html)
CN (1) CN103748215A (cg-RX-API-DMAC7.html)
AU (1) AU2012239874A1 (cg-RX-API-DMAC7.html)
BR (1) BR112013025957A2 (cg-RX-API-DMAC7.html)
CA (1) CA2832592A1 (cg-RX-API-DMAC7.html)
RU (1) RU2013147265A (cg-RX-API-DMAC7.html)
WO (1) WO2012139131A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015520174A (ja) * 2012-05-31 2015-07-16 ネオステム，インコーポレイティド 眼疾患を治療するためのヒト極小胚様（ｖｓｅｌ）幹細胞
WO2014089268A2 (en) 2012-12-06 2014-06-12 StemBios Technologies, Inc. Lgr5+ somatic stem cells
US20160008506A1 (en) * 2013-03-07 2016-01-14 Neostem, Inc. Stem cell compositions and methods for would healing
HK1232131A1 (zh) * 2014-11-19 2018-01-05 干细胞生物科技公司 用於治疗骨骼缺损的体干细胞
CN106106443A (zh) * 2016-06-23 2016-11-16 松桃如阿雅观光农业产业开发有限公司 红肉蜜柚防治病虫害药剂
CN114732962B (zh) * 2022-05-20 2023-06-20 武汉理工大学 一种可降解的抗菌引导骨再生膜及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1974018A4 (en) * 2005-12-08 2010-01-27 Univ Louisville Res Found VSEL (VERY SMALL EMBRYONIC LIKE) STEM CELLS AND METHOD OF ISOLATING AND USE THEREOF
PL1989295T3 (pl) * 2006-02-16 2021-02-22 Université Libre de Bruxelles Różnicowanie osteogenne komórek macierzystych szpiku kostnego oraz komórki i populacje osteoprogenitorowe lub osteoblastyczne
US8574567B2 (en) * 2007-05-03 2013-11-05 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
EP2214497A4 (en) * 2007-10-30 2010-11-24 Univ Louisville Res Found USES AND ISOLATION OF VERY SMALL EMBRYONIC TYPE STEM CELLS (VSEL)
WO2009154840A2 (en) * 2008-03-27 2009-12-23 Neostem, Inc. Compositions and methods using stem cells in cutaneous wound healing
US20120021482A1 (en) * 2008-09-30 2012-01-26 Zuba-Surma Ewa K Methods for isolating very small embryonic-like (vsel) stem cells

Also Published As

Publication number Publication date
AU2012239874A1 (en) 2013-10-31
CN103748215A (zh) 2014-04-23
CA2832592A1 (en) 2012-10-11
WO2012139131A1 (en) 2012-10-11
BR112013025957A2 (pt) 2016-09-20
JP2014511864A (ja) 2014-05-19
EP2694641A1 (en) 2014-02-12
EP2694641A4 (en) 2014-11-19
US20140112891A1 (en) 2014-04-24

Similar Documents

Publication Publication Date Title
Polymeri et al. Bone marrow stromal stem cells in tissue engineering and regenerative medicine
Makris et al. The knee meniscus: structure–function, pathophysiology, current repair techniques, and prospects for regeneration
Bartold et al. Mesenchymal stem cells and biologic factors leading to bone formation
RU2013147265A (ru) РЕГЕНЕРАЦИЯ КОСТЕЙ И ХРЯЩЕЙ С ПОМОЩЬЮ АУТОЛОГИЧНЫХ ПЛЮРИПОТЕНТНЫХ ОЧЕНЬ МАЛЕНЬКИХ ЭМБРИОНОПОДОБНЫХ (hVSEL) СТВОЛОВЫХ КЛЕТОК ВЗРОСЛЫХ ЛЮДЕЙ
Filardo et al. Mesenchymal stem cells for the treatment of cartilage lesions: from preclinical findings to clinical application in orthopaedics
Nourissat et al. Mesenchymal stem cell therapy regenerates the native bone-tendon junction after surgical repair in a degenerative rat model
Volk et al. Translating stem cell therapies: the role of companion animals in regenerative medicine
Rivera-Izquierdo et al. An updated review of adipose derived-mesenchymal stem cells and their applications in musculoskeletal disorders
Diederichs et al. The promise and challenges of stem cell‐based therapies for skeletal diseases: stem cell applications in skeletal medicine: potential, cell sources and characteristics, and challenges of clinical translation
Whitworth et al. Stem cell therapies for treating osteoarthritis: prescient or premature?
JP2014196354A5 (cg-RX-API-DMAC7.html)
Pang et al. Synergistic effects of ultrashort wave and bone marrow stromal cells on nerve regeneration with acellular nerve allografts
Kalpakci et al. Assessment of growth factor treatment on fibrochondrocyte and chondrocyte co-cultures for TMJ fibrocartilage engineering
AR047712A1 (es) Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas
WO2010033088A8 (en) Method of improving differentiation of chondrogenic progenitor cells
Brehm et al. Stem cell-based tissue engineering in veterinary orthopaedics
RU2017120359A (ru) Индукция остеогенеза путем внедрения рнк, кодирующей костной морфогенетический белок (кмб)
Hassanzadeh et al. Recent advances in mesenchymal stem/stromal cells (MSCs)‐based approaches for osteoarthritis (OA) therapy
JP2014511864A5 (cg-RX-API-DMAC7.html)
Zhang et al. Tendon-derived stem cells as a new cell source for tendon tissue engineering
Campbell et al. The hunt is on! In pursuit of the ideal stem cell population for cartilage regeneration
CA et al. Mesenchymal stem cells seeded decellularized tendon scaffold for tissue engineering
Giuseppe Longo et al. Potential of adipose derived stem cells in orthopaedic surgery
Zhang et al. The effects of mesenchymal stem cells in craniofacial tissue engineering
Gui et al. Isolation and characterization of meniscus derived stem cells from rabbit as a possible treatment for damaged meniscus

Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20160927