RU2009141168A - Способы и композиции, содержащие дезвенлафаксин или дулоксетин, для лечения расстройств дыхания во время сна - Google Patents
Способы и композиции, содержащие дезвенлафаксин или дулоксетин, для лечения расстройств дыхания во время сна Download PDFInfo
- Publication number
- RU2009141168A RU2009141168A RU2009141168/15A RU2009141168A RU2009141168A RU 2009141168 A RU2009141168 A RU 2009141168A RU 2009141168/15 A RU2009141168/15 A RU 2009141168/15A RU 2009141168 A RU2009141168 A RU 2009141168A RU 2009141168 A RU2009141168 A RU 2009141168A
- Authority
- RU
- Russia
- Prior art keywords
- desmethylvenlafaxine
- agent
- duloxetine
- patient
- respiratory
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract 23
- ZEUITGRIYCTCEM-KRWDZBQOSA-N (S)-duloxetine Chemical compound C1([C@@H](OC=2C3=CC=CC=C3C=CC=2)CCNC)=CC=CS1 ZEUITGRIYCTCEM-KRWDZBQOSA-N 0.000 title claims abstract 8
- 229960002866 duloxetine Drugs 0.000 title claims abstract 8
- 230000004064 dysfunction Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- KYYIDSXMWOZKMP-UHFFFAOYSA-N O-desmethylvenlafaxine Chemical compound C1CCCCC1(O)C(CN(C)C)C1=CC=C(O)C=C1 KYYIDSXMWOZKMP-UHFFFAOYSA-N 0.000 claims abstract 14
- 239000013543 active substance Substances 0.000 claims abstract 8
- 239000003795 chemical substances by application Substances 0.000 claims abstract 8
- 208000007590 Disorders of Excessive Somnolence Diseases 0.000 claims abstract 4
- 206010041349 Somnolence Diseases 0.000 claims abstract 4
- 239000000883 anti-obesity agent Substances 0.000 claims abstract 4
- 229940125710 antiobesity agent Drugs 0.000 claims abstract 4
- 230000000694 effects Effects 0.000 claims abstract 4
- 210000001034 respiratory center Anatomy 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 239000012453 solvate Substances 0.000 claims abstract 4
- 208000023504 respiratory system disease Diseases 0.000 claims abstract 3
- KYYIDSXMWOZKMP-OAHLLOKOSA-N 4-[(1s)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol Chemical compound C1([C@@H](CN(C)C)C2(O)CCCCC2)=CC=C(O)C=C1 KYYIDSXMWOZKMP-OAHLLOKOSA-N 0.000 claims abstract 2
- 206010038687 Respiratory distress Diseases 0.000 claims abstract 2
- 239000006187 pill Substances 0.000 claims 2
- 208000001797 obstructive sleep apnea Diseases 0.000 claims 1
- 230000000147 hypnotic effect Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92246607P | 2007-04-09 | 2007-04-09 | |
| US60/922,466 | 2007-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2009141168A true RU2009141168A (ru) | 2011-05-20 |
Family
ID=39831524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009141168/15A RU2009141168A (ru) | 2007-04-09 | 2008-04-08 | Способы и композиции, содержащие дезвенлафаксин или дулоксетин, для лечения расстройств дыхания во время сна |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20080293823A1 (https=) |
| EP (2) | EP2455076A1 (https=) |
| JP (1) | JP2010523662A (https=) |
| KR (1) | KR20100015923A (https=) |
| CN (1) | CN101686955A (https=) |
| AR (1) | AR065989A1 (https=) |
| AU (1) | AU2008236624A1 (https=) |
| BR (1) | BRPI0810159A2 (https=) |
| CA (1) | CA2683697C (https=) |
| IL (1) | IL201430A0 (https=) |
| MX (1) | MX2009010805A (https=) |
| NZ (1) | NZ580250A (https=) |
| RU (1) | RU2009141168A (https=) |
| TW (1) | TW200901956A (https=) |
| WO (1) | WO2008124128A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2012007813A (es) * | 2010-01-07 | 2012-08-01 | Vivus Inc | Tratamiento del sindrome de apnea obstructiva del sueño con una combinacion de un hinibidor de anhidrasa carbonica y un agente activo adicional. |
| WO2011155797A2 (ko) * | 2010-06-10 | 2011-12-15 | 동아제약 주식회사 | 결정형 오-데스메틸벤라팍신의 헤미옥살레이트염, 그의 제조방법 및 그의 약제학적 조성물 |
| EP3746126B1 (en) | 2018-01-30 | 2024-07-31 | Apnimed, Inc. (Delaware) | Methods and compositions for treating sleep apnea or simple snoring |
| EP4635514A3 (en) * | 2019-02-08 | 2025-12-24 | The Brigham & Women's Hospital, Inc. | Methods and compositions for treating sleep apnea |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172896A (en) | 1978-06-05 | 1979-10-30 | Dainippon Pharmaceutical Co., Ltd. | Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same |
| US5803066A (en) * | 1992-05-07 | 1998-09-08 | New York University | Method and apparatus for optimizing the continuous positive airway pressure for treating obstructive sleep apnea |
| GB9217295D0 (en) | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| US5358970A (en) | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
| US5541231A (en) | 1993-07-30 | 1996-07-30 | Glaxo Wellcome Inc. | Stabilized Pharmaceutical |
| GB9315856D0 (en) | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| US6150396A (en) * | 1997-03-07 | 2000-11-21 | Eli Lilly And Company | Methods of treating or preventing interstitial cystitis |
| US6110973A (en) | 1998-01-29 | 2000-08-29 | Sepracor | Methods for treating obesity and weight gain using optically pure (-)-bupropion |
| US7160898B2 (en) * | 2001-12-14 | 2007-01-09 | Board Of Trustees Of The University Of Illinois | Pharmacological treatment for sleep apnea |
| DE60039132D1 (de) * | 1999-04-06 | 2008-07-17 | Sepracor Inc | O-Desmethylvenlafaxin-Succinat |
| WO2000076955A1 (en) * | 1999-06-15 | 2000-12-21 | American Home Products Corporation | Enantiomers of o-desmethyl venlafaxine |
| US7355042B2 (en) * | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
| NZ548856A (en) * | 2004-02-17 | 2009-10-30 | Transcept Pharmaceuticals Inc | Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof |
| US20060039867A1 (en) * | 2004-08-20 | 2006-02-23 | Cypress Bioscience, Inc. | Method for treating sleep-related breathing disorders with setiptiline |
| KR20070087678A (ko) * | 2004-12-20 | 2007-08-28 | 컬리지움 파마슈티칼, 인코포레이티드 | 수면 장애용 약제 조성물 |
| AU2006255047B2 (en) * | 2005-06-06 | 2011-09-15 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating sleep disorders |
| WO2007026219A2 (en) * | 2005-08-31 | 2007-03-08 | Pfizer Products Inc. | Combinations of a 5-ht1b antagonist with a noradrenalin re-uptake inhibitor or a serotonin noradrenalin reutake inhibitor for treating cns conditions |
| KR101528326B1 (ko) * | 2007-02-21 | 2015-06-11 | 선오비온 파마슈티컬스 인코포레이티드 | （―）ｏ―데스메틸벤라팍신을 포함하는 고체 형태들 및 그들의 용도 |
| US20090048233A1 (en) * | 2007-08-16 | 2009-02-19 | Cypress Biosciences, Inc. | Enhancing the Tolerability of a Seratonin Antagonist and a NSRI, a SNRI or a RIMA by Using Them in Combination |
-
2008
- 2008-04-08 EP EP12154458A patent/EP2455076A1/en not_active Withdrawn
- 2008-04-08 RU RU2009141168/15A patent/RU2009141168A/ru not_active Application Discontinuation
- 2008-04-08 CA CA2683697A patent/CA2683697C/en not_active Expired - Fee Related
- 2008-04-08 JP JP2010503031A patent/JP2010523662A/ja active Pending
- 2008-04-08 AR ARP080101456A patent/AR065989A1/es unknown
- 2008-04-08 WO PCT/US2008/004508 patent/WO2008124128A2/en not_active Ceased
- 2008-04-08 NZ NZ580250A patent/NZ580250A/en not_active IP Right Cessation
- 2008-04-08 BR BRPI0810159-0A2A patent/BRPI0810159A2/pt not_active Application Discontinuation
- 2008-04-08 KR KR1020097022364A patent/KR20100015923A/ko not_active Withdrawn
- 2008-04-08 AU AU2008236624A patent/AU2008236624A1/en not_active Abandoned
- 2008-04-08 MX MX2009010805A patent/MX2009010805A/es not_active Application Discontinuation
- 2008-04-08 CN CN200880018706A patent/CN101686955A/zh active Pending
- 2008-04-08 EP EP08742623A patent/EP2142183A2/en not_active Withdrawn
- 2008-04-09 US US12/100,382 patent/US20080293823A1/en not_active Abandoned
- 2008-04-09 TW TW097112888A patent/TW200901956A/zh unknown
-
2009
- 2009-10-11 IL IL201430A patent/IL201430A0/en unknown
-
2012
- 2012-05-25 US US13/481,597 patent/US20120238616A1/en not_active Abandoned
-
2015
- 2015-03-27 US US14/670,523 patent/US20150196531A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009010805A (es) | 2009-10-29 |
| JP2010523662A (ja) | 2010-07-15 |
| TW200901956A (en) | 2009-01-16 |
| BRPI0810159A2 (pt) | 2014-12-30 |
| EP2142183A2 (en) | 2010-01-13 |
| US20150196531A1 (en) | 2015-07-16 |
| KR20100015923A (ko) | 2010-02-12 |
| CN101686955A (zh) | 2010-03-31 |
| AU2008236624A1 (en) | 2008-10-16 |
| AR065989A1 (es) | 2009-07-15 |
| IL201430A0 (en) | 2010-05-31 |
| US20080293823A1 (en) | 2008-11-27 |
| US20120238616A1 (en) | 2012-09-20 |
| WO2008124128A3 (en) | 2009-05-07 |
| NZ580250A (en) | 2012-05-25 |
| EP2455076A1 (en) | 2012-05-23 |
| WO2008124128A2 (en) | 2008-10-16 |
| CA2683697A1 (en) | 2008-10-16 |
| CA2683697C (en) | 2016-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20121221 |