RU2008122918A - Способ получения олигосахаридов - Google Patents
Способ получения олигосахаридов Download PDFInfo
- Publication number
- RU2008122918A RU2008122918A RU2008122918/13A RU2008122918A RU2008122918A RU 2008122918 A RU2008122918 A RU 2008122918A RU 2008122918/13 A RU2008122918/13 A RU 2008122918/13A RU 2008122918 A RU2008122918 A RU 2008122918A RU 2008122918 A RU2008122918 A RU 2008122918A
- Authority
- RU
- Russia
- Prior art keywords
- gal
- glc
- milk
- lactose
- culture
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 229920001542 oligosaccharide Polymers 0.000 title 1
- 150000002482 oligosaccharides Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract 8
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract 6
- DLRVVLDZNNYCBX-JZSVMVJISA-N beta-D-Galp-(1->6)-D-Galp Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-JZSVMVJISA-N 0.000 claims abstract 6
- 239000008101 lactose Substances 0.000 claims abstract 6
- 235000013336 milk Nutrition 0.000 claims abstract 5
- 239000008267 milk Substances 0.000 claims abstract 5
- 210000004080 milk Anatomy 0.000 claims abstract 5
- 241000186016 Bifidobacterium bifidum Species 0.000 claims abstract 4
- 235000021255 galacto-oligosaccharides Nutrition 0.000 claims abstract 4
- 150000003271 galactooligosaccharides Chemical class 0.000 claims abstract 4
- 239000000203 mixture Substances 0.000 claims abstract 4
- 239000000758 substrate Substances 0.000 claims abstract 4
- 241000894006 Bacteria Species 0.000 claims abstract 2
- 241000283690 Bos taurus Species 0.000 claims abstract 2
- 241000283707 Capra Species 0.000 claims abstract 2
- 241001494479 Pecora Species 0.000 claims abstract 2
- 239000005862 Whey Substances 0.000 claims abstract 2
- 102000007544 Whey Proteins Human genes 0.000 claims abstract 2
- 108010046377 Whey Proteins Proteins 0.000 claims abstract 2
- 229940002008 bifidobacterium bifidum Drugs 0.000 claims abstract 2
- 238000004113 cell culture Methods 0.000 claims abstract 2
- 150000002016 disaccharides Chemical class 0.000 claims abstract 2
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims abstract 2
- 235000020183 skimmed milk Nutrition 0.000 claims abstract 2
- 238000003786 synthesis reaction Methods 0.000 claims abstract 2
- 150000004044 tetrasaccharides Chemical class 0.000 claims abstract 2
- 150000004043 trisaccharides Chemical class 0.000 claims abstract 2
- 235000019871 vegetable fat Nutrition 0.000 claims abstract 2
- 235000008939 whole milk Nutrition 0.000 claims abstract 2
- 230000003247 decreasing effect Effects 0.000 claims 1
- 235000020161 semi-skimmed milk Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
1. Способ получения смеси галактоолигосахаридов, содержащей дисахарид Gal(α1-6)-Gal, по меньшей мере, один трисахарид, выбранный из Gal(β1-6)-Gal(β1-4)-Glc, Gal(β1-3)-Gal(β1-4)-Glc, тетрасахарид Gal(β1-6)-Gal(β1-6)-Gal(β1-4) Glc и пентасахарид Gal(β1-6)-Gal(β1-6)-Gal(β1-6)-Gal(β1-4)-Glc, где Gal представляет собой галактозный остаток, и Glc представляет собой глюкозный остаток, где добавляют культуру клеток Bifidobacterium bifidum к лактозе или субстрату, содержащему лактозу, отличающийся тем, что указанные клетки повторно используют до восьми раз в последующих реакциях синтеза без уменьшения выхода указанной смеси галактоолигосахаридов. ! 2. Способ по п.1, где указанная культура B.bifidum представляет собой культуру штамма NCIMB 41171, депонированного в National Collection of Industrial and Marine Bacteria, Aberdeen, UK, 31 марта 2003, или биологически функциональный эквивалент, который здесь определен. ! 3. Способ по п.1 или 2, где субстрат, содержащий лактозу, выбран из группы, включающей цельное молоко, полуснятое молоко, снятое молоко, сыворотку и заменитель молока с растительным жиром. ! 4. Способ по п.3, где молоко получают от крупного рогатого скота, буйволиц, овец или коз.
Claims (4)
1. Способ получения смеси галактоолигосахаридов, содержащей дисахарид Gal(α1-6)-Gal, по меньшей мере, один трисахарид, выбранный из Gal(β1-6)-Gal(β1-4)-Glc, Gal(β1-3)-Gal(β1-4)-Glc, тетрасахарид Gal(β1-6)-Gal(β1-6)-Gal(β1-4) Glc и пентасахарид Gal(β1-6)-Gal(β1-6)-Gal(β1-6)-Gal(β1-4)-Glc, где Gal представляет собой галактозный остаток, и Glc представляет собой глюкозный остаток, где добавляют культуру клеток Bifidobacterium bifidum к лактозе или субстрату, содержащему лактозу, отличающийся тем, что указанные клетки повторно используют до восьми раз в последующих реакциях синтеза без уменьшения выхода указанной смеси галактоолигосахаридов.
2. Способ по п.1, где указанная культура B.bifidum представляет собой культуру штамма NCIMB 41171, депонированного в National Collection of Industrial and Marine Bacteria, Aberdeen, UK, 31 марта 2003, или биологически функциональный эквивалент, который здесь определен.
3. Способ по п.1 или 2, где субстрат, содержащий лактозу, выбран из группы, включающей цельное молоко, полуснятое молоко, снятое молоко, сыворотку и заменитель молока с растительным жиром.
4. Способ по п.3, где молоко получают от крупного рогатого скота, буйволиц, овец или коз.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0522740.0A GB0522740D0 (en) | 2005-11-08 | 2005-11-08 | Process for the production of oligosaccharides |
| GB0522740.0 | 2005-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2008122918A true RU2008122918A (ru) | 2009-12-20 |
Family
ID=35516528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008122918/13A RU2008122918A (ru) | 2005-11-08 | 2006-11-02 | Способ получения олигосахаридов |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20090155860A1 (ru) |
| EP (1) | EP1945787A2 (ru) |
| JP (1) | JP2009514543A (ru) |
| KR (1) | KR20080086979A (ru) |
| CN (1) | CN101341255A (ru) |
| AU (1) | AU2006311107A1 (ru) |
| BR (1) | BRPI0618300A2 (ru) |
| CA (1) | CA2628671A1 (ru) |
| GB (2) | GB0522740D0 (ru) |
| NO (1) | NO20082094L (ru) |
| RU (1) | RU2008122918A (ru) |
| WO (1) | WO2007054459A2 (ru) |
| ZA (1) | ZA200803921B (ru) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006012536A2 (en) | 2004-07-22 | 2006-02-02 | Ritter Andrew J | Methods and compositions for treating lactose intolerance |
| GB0525857D0 (en) | 2005-12-20 | 2006-02-01 | Product and process | |
| GB0601901D0 (en) | 2006-01-31 | 2006-03-08 | Product and Process | |
| GB0606112D0 (en) | 2006-03-28 | 2006-05-03 | Product and process | |
| SG10201901259RA (en) | 2009-02-24 | 2019-03-28 | Ritter Pharmaceuticals Inc | Prebiotic formulations and methods of use |
| BRPI0925002A2 (pt) | 2009-05-27 | 2016-06-21 | Clasado Inc | uso de uma composição para a prevenção de diarréia |
| WO2011137249A1 (en) | 2010-04-28 | 2011-11-03 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
| CA2805997A1 (en) * | 2010-07-19 | 2012-01-26 | Arla Foods Amba | Galacto-oligosaccharide-containing composition and a method of producing it |
| US20150183816A1 (en) * | 2012-06-22 | 2015-07-02 | Glycom A/S | Modified galactooligosaccharides |
| ES2453205B1 (es) * | 2012-09-04 | 2015-03-13 | Univ Valencia Politecnica | Liberacion de sustancias en celulas senescentes |
| US20160168608A1 (en) * | 2013-07-23 | 2016-06-16 | Neo Cremar Co., Ltd. | A preparation method of galactooligosaccharides with enhanced galactosyllactose which is a ingredient of mother's milk |
| JPWO2020262414A1 (ru) * | 2019-06-25 | 2020-12-30 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3782716T2 (de) * | 1986-09-27 | 1993-04-01 | Unitika Ltd | Verfahren zum herstellung eines wachstumsfaktors fuer bifidobacterium sp. |
| CA2520043C (en) * | 2003-06-30 | 2009-09-01 | Clasado Inc. | Novel galactooligosaccharide composition and the preparation thereof |
-
2005
- 2005-11-08 GB GBGB0522740.0A patent/GB0522740D0/en not_active Ceased
-
2006
- 2006-11-02 CN CNA2006800416294A patent/CN101341255A/zh active Pending
- 2006-11-02 KR KR1020087013631A patent/KR20080086979A/ko not_active Application Discontinuation
- 2006-11-02 RU RU2008122918/13A patent/RU2008122918A/ru not_active Application Discontinuation
- 2006-11-02 BR BRPI0618300-0A patent/BRPI0618300A2/pt not_active Application Discontinuation
- 2006-11-02 WO PCT/EP2006/068029 patent/WO2007054459A2/en active Application Filing
- 2006-11-02 GB GB0807808A patent/GB2445137A/en not_active Withdrawn
- 2006-11-02 EP EP06829927A patent/EP1945787A2/en not_active Withdrawn
- 2006-11-02 AU AU2006311107A patent/AU2006311107A1/en not_active Abandoned
- 2006-11-02 US US12/084,681 patent/US20090155860A1/en not_active Abandoned
- 2006-11-02 CA CA002628671A patent/CA2628671A1/en not_active Abandoned
- 2006-11-02 JP JP2008539403A patent/JP2009514543A/ja active Pending
-
2008
- 2008-05-06 NO NO20082094A patent/NO20082094L/no not_active Application Discontinuation
- 2008-05-07 ZA ZA200803921A patent/ZA200803921B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB2445137A (en) | 2008-06-25 |
| EP1945787A2 (en) | 2008-07-23 |
| CN101341255A (zh) | 2009-01-07 |
| AU2006311107A2 (en) | 2008-06-19 |
| WO2007054459A2 (en) | 2007-05-18 |
| GB0522740D0 (en) | 2005-12-14 |
| NO20082094L (no) | 2008-05-29 |
| GB0807808D0 (en) | 2008-06-04 |
| BRPI0618300A2 (pt) | 2011-08-23 |
| CA2628671A1 (en) | 2007-05-18 |
| AU2006311107A1 (en) | 2007-05-18 |
| KR20080086979A (ko) | 2008-09-29 |
| US20090155860A1 (en) | 2009-06-18 |
| JP2009514543A (ja) | 2009-04-09 |
| ZA200803921B (en) | 2009-04-29 |
| WO2007054459A3 (en) | 2007-07-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20100315 |