RU2008106636A - Аппарат для излучения и детектирования лучей света - Google Patents

Аппарат для излучения и детектирования лучей света Download PDF

Info

Publication number
RU2008106636A
RU2008106636A RU2008106636/14A RU2008106636A RU2008106636A RU 2008106636 A RU2008106636 A RU 2008106636A RU 2008106636/14 A RU2008106636/14 A RU 2008106636/14A RU 2008106636 A RU2008106636 A RU 2008106636A RU 2008106636 A RU2008106636 A RU 2008106636A
Authority
RU
Russia
Prior art keywords
light
sources
exciting
rotating wheel
excitation
Prior art date
Application number
RU2008106636/14A
Other languages
English (en)
Russian (ru)
Inventor
Роджер ИТЕН (CH)
Роджер ИТЕН
Original Assignee
Ф. Хоффманн-Ля Рош Аг (Ch)
Ф. Хоффманн-Ля Рош Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ф. Хоффманн-Ля Рош Аг (Ch), Ф. Хоффманн-Ля Рош Аг filed Critical Ф. Хоффманн-Ля Рош Аг (Ch)
Publication of RU2008106636A publication Critical patent/RU2008106636A/ru

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0235Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using means for replacing an element by another, for replacing a filter or a grating
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/10Arrangements of light sources specially adapted for spectrometry or colorimetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/30Measuring the intensity of spectral lines directly on the spectrum itself
    • G01J3/32Investigating bands of a spectrum in sequence by a single detector
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6471Special filters, filter wheel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • G01N2201/0627Use of several LED's for spectral resolution

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
RU2008106636/14A 2007-02-21 2008-02-20 Аппарат для излучения и детектирования лучей света RU2008106636A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07102771A EP1962084A1 (en) 2007-02-21 2007-02-21 Apparatus for emitting and detecting beams of light
EP07102771.8 2007-02-21

Publications (1)

Publication Number Publication Date
RU2008106636A true RU2008106636A (ru) 2009-08-27

Family

ID=38082647

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008106636/14A RU2008106636A (ru) 2007-02-21 2008-02-20 Аппарат для излучения и детектирования лучей света

Country Status (7)

Country Link
US (1) US7947442B2 (enExample)
EP (2) EP1962084A1 (enExample)
JP (1) JP2008261842A (enExample)
CN (1) CN101251486A (enExample)
AU (1) AU2008200772A1 (enExample)
CA (1) CA2621877A1 (enExample)
RU (1) RU2008106636A (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011016509A1 (ja) * 2009-08-06 2011-02-10 ユニバーサル・バイオ・リサーチ株式会社 光ファイバ測定装置およびその測定方法
EP2525211B1 (en) 2011-05-16 2018-01-03 F. Hoffmann-La Roche AG Instrument and method for detecting analytes
JP5976128B2 (ja) * 2011-12-22 2016-08-23 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 光学システムにおける光源寿命の延長
GB201209738D0 (en) * 2012-05-31 2012-07-18 Ge Healthcare Bio Sciences Ab Methods and apparatus for measuring the concentration of a substance in a solution
US9556477B2 (en) 2012-07-17 2017-01-31 Universal Bio Research Co., Ltd. Light measurement apparatus for reaction vessel and light measurement method
CA2879638A1 (en) 2012-08-10 2014-02-13 Streck, Inc. Real-time optical system for polymerase chain reaction
CA2862766C (en) 2012-12-05 2016-01-19 Genepoc Inc. Optical interrogation device
AU2015275317A1 (en) * 2013-03-14 2016-01-21 Gen-Probe Incorporated Indexing signal detection module
AU2013202788B2 (en) 2013-03-14 2015-10-01 Gen-Probe Incorporated Indexing signal detection module
PL3011318T3 (pl) * 2013-06-19 2019-05-31 Ellume Pty Ltd Urządzenie testujące wykorzystujące znaczniki fluorescencyjne
US10006861B2 (en) 2013-06-28 2018-06-26 Streck, Inc. Devices for real-time polymerase chain reaction
KR102126032B1 (ko) * 2013-07-31 2020-07-08 삼성전자주식회사 다채널 형광 검출 모듈 및 이를 포함하는 핵산 분석 시스템
FI128285B (en) * 2014-06-27 2020-02-28 Metso Automation Oy Multichannel optical measurement unit, multichannel optical detector unit and related measurement method
CN104614351A (zh) * 2015-01-21 2015-05-13 南京中科神光科技有限公司 一种快速、多通道实时荧光定量检测装置
CN113049553B (zh) * 2015-02-06 2024-08-20 生命技术公司 用于评价生物样本的系统和方法
CN106680250B (zh) 2015-11-10 2023-06-30 北京万泰生物药业股份有限公司 用于聚合酶链式反应的检测机构及聚合酶链式反应装置
GB201603380D0 (en) 2016-02-26 2016-04-13 Ge Healthcare Bio Sciences Ab Apparatus and method for measuring the light absorbance of a substance in a solution
SE1650816A1 (en) * 2016-06-10 2017-11-21 Bomill Ab A detector system comprising a plurality of light guides and a spectrometer comprising the detector system
TWI586957B (zh) * 2016-06-24 2017-06-11 諾貝爾生物有限公司 多通道螢光檢測系統及其方法
CN107101945A (zh) * 2017-05-26 2017-08-29 北京智云达科技股份有限公司 一种多通道多波长光谱检测装置
US11585760B2 (en) 2017-07-26 2023-02-21 Gen-Probe Incorporated Optical signal detection modules and methods
CN107478629A (zh) * 2017-09-04 2017-12-15 中国科学院苏州生物医学工程技术研究所 一种大面积数字pcr微滴荧光高通量检测装置和方法
WO2020175937A1 (en) 2019-02-27 2020-09-03 Seegene, Inc. Light module
WO2020242263A1 (en) * 2019-05-31 2020-12-03 Seegene, Inc. Device and method for detecting light
EP4127677A4 (en) * 2020-03-31 2024-04-24 Seegene, Inc. OPTICAL SIGNAL DETECTION DEVICE
KR102503418B1 (ko) * 2020-11-06 2023-02-27 (주)바이오젠텍 형광 다중 유전자 등온증폭기
CN113607937B (zh) * 2020-12-30 2022-07-12 北京中科生仪科技有限公司 一种pcr检测方法的数据处理方法
WO2023032256A1 (ja) * 2021-09-03 2023-03-09 ソニーセミコンダクタソリューションズ株式会社 分光感度測定装置及び分光感度測定方法
CN118202229A (zh) * 2021-10-20 2024-06-14 生物辐射实验室股份有限公司 荧光检测系统
EP4650753A1 (de) 2024-05-15 2025-11-19 Gerbion GmbH & Co. KG Vorrichtung zur lumineszenzdetektion für temperaturabhängige reaktionssysteme

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477190A (en) * 1981-07-20 1984-10-16 American Hospital Supply Corporation Multichannel spectrophotometer
ES8706823A1 (es) 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1339653C (en) 1986-02-25 1998-02-03 Larry J. Johnson Appartus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
DE4424961C2 (de) 1993-07-15 2002-05-08 Perkin Elmer Corp Wählvorrichtung für ein photometrisches Instrument mit Lichtleitfasern zur Analyse von entfernt befindlichen Proben
US6597450B1 (en) * 1997-09-15 2003-07-22 Becton, Dickinson And Company Automated Optical Reader for Nucleic Acid Assays
US6326605B1 (en) * 1998-02-20 2001-12-04 Ljl Biosystems, Inc. Broad range light detection system
US6369893B1 (en) * 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
EP0953838A1 (en) * 1998-05-01 1999-11-03 F. Hoffmann-La Roche Ag Apparatus for simultaneously monitoring reactions taking place in a plurality of reaction vessels
EP0953837A1 (en) 1998-05-01 1999-11-03 F. Hoffmann-La Roche Ag Fluorescence light measuring device and an apparatus wherein such a device is used
DE10131687A1 (de) 2001-06-29 2003-01-16 Eppendorf Ag Vorrichtung zur Durchführung von Nukleinsäure-Amplifikationsreaktionen bei gleichzeitiger Verfolgung der Bildung von Amplifikationsprodukten
US6856390B2 (en) * 2001-07-25 2005-02-15 Applera Corporation Time-delay integration in electrophoretic detection systems
US7280207B2 (en) * 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
ES2543587T3 (es) 2002-05-17 2015-08-20 Life Technologies Corporation Instrumento óptico que incluye una fuente de excitación
JP2004147706A (ja) * 2002-10-28 2004-05-27 Matsushita Electric Works Ltd 非侵襲型生体成分の定量装置及び定量方法
CN101793826B (zh) * 2004-06-07 2016-04-13 先锋生物科技股份有限公司 用于微流体器件的光学透镜系统和方法
KR100647317B1 (ko) * 2005-02-03 2006-11-23 삼성전자주식회사 다채널 형광 측정용 광학계 및 이를 채용한 다채널 형광시료 분석 장치
US7791728B2 (en) * 2005-08-11 2010-09-07 Hewlett-Packard Development Company, L.P. System for optically analyzing a substance with a selected single-wavelength
EP1991357B1 (en) * 2006-02-07 2016-09-14 Stokes Bio Limited A microfluidic analysis system

Also Published As

Publication number Publication date
US7947442B2 (en) 2011-05-24
EP1962085A2 (en) 2008-08-27
EP1962084A1 (en) 2008-08-27
JP2008261842A (ja) 2008-10-30
CA2621877A1 (en) 2008-08-21
US20090068747A1 (en) 2009-03-12
AU2008200772A1 (en) 2008-09-04
EP1962085A3 (en) 2008-09-24
CN101251486A (zh) 2008-08-27

Similar Documents

Publication Publication Date Title
RU2008106636A (ru) Аппарат для излучения и детектирования лучей света
JP2008261842A5 (enExample)
BRPI0609544B8 (pt) dispositivo de detecção, sistema de detecção, e, método
BRPI0609769B8 (pt) dispositivo de detecção, sistema de detecção, e, método
JP5688034B2 (ja) 高品質生物医学装置の照明設計
EP1830174A3 (en) Multi-channel fluorescence measuring optical system and multi-channel fluorescence sample analyzer
CN104677870A (zh) 一种超小型化多通道实时荧光光谱检测装置
JP2009526239A (ja) モジュール方式の蛍光測定および光度測定読取装置
US7199879B2 (en) Versatile instrumentation for optical measurement of samples
EA013886B1 (ru) Система для обнаружения флуоресценции
TW200710381A (en) Heating element for a rotating multiplex fluorescence detection device
JP2007263911A5 (enExample)
WO2009125974A3 (en) Multi-channel bio reactor with fluorescence detector and on-line monitoring apparatus of it
JP2013518270A5 (enExample)
US7843568B2 (en) Enhanced instrumentation and method for optical measurement of samples
JP2013518270A (ja) 特に、血中グルコースを測定するための、測定装置および測定方法
US20120313008A1 (en) Fluorescent detector
JPH10281994A (ja) 蛍光測定装置
JP4665097B2 (ja) 光源ユニット、受光ユニット及びこれらを用いたマルチチャンネル光検出装置
US9989465B2 (en) Multi-channel fluorescence detecting system and method of using the same
US5094531A (en) Spectrophotometer to fluorometer converter
JP2010043983A (ja) 光学測定装置
JP6820122B2 (ja) 選択可能な励起光経路を用いる光学ベースの測定のための方法およびシステム
CN217709486U (zh) 一种光控核酸检测装置
WO2008132325A3 (fr) Dispositif de lecture de fluorescence

Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20120815