RU2004131858A - Согревающие и нераздражающие безводные смазывающие композиции - Google Patents
Согревающие и нераздражающие безводные смазывающие композиции Download PDFInfo
- Publication number
- RU2004131858A RU2004131858A RU2004131858/15A RU2004131858A RU2004131858A RU 2004131858 A RU2004131858 A RU 2004131858A RU 2004131858/15 A RU2004131858/15 A RU 2004131858/15A RU 2004131858 A RU2004131858 A RU 2004131858A RU 2004131858 A RU2004131858 A RU 2004131858A
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- Prior art keywords
- composition according
- agent
- composition
- polyethylene glycol
- glycol
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims 23
- 238000010438 heat treatment Methods 0.000 title 1
- 239000002085 irritant Substances 0.000 title 1
- 239000000314 lubricant Substances 0.000 title 1
- 239000004599 antimicrobial Substances 0.000 claims 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical group CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- 239000003349 gelling agent Substances 0.000 claims 3
- 150000005846 sugar alcohols Polymers 0.000 claims 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- -1 alkylene glycol Chemical compound 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 235000014655 lactic acid Nutrition 0.000 claims 2
- 239000004310 lactic acid Substances 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 1
- 208000005171 Dysmenorrhea Diseases 0.000 claims 1
- 206010013935 Dysmenorrhoea Diseases 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 239000003429 antifungal agent Substances 0.000 claims 1
- 229940121375 antifungal agent Drugs 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 239000003589 local anesthetic agent Substances 0.000 claims 1
- 230000001050 lubricating effect Effects 0.000 claims 1
- 239000003002 pH adjusting agent Substances 0.000 claims 1
- 229940068886 polyethylene glycol 300 Drugs 0.000 claims 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Anesthesiology (AREA)
- Inorganic Chemistry (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (19)
1. По существу, безводная смазывающая композиция, включающая, по меньшей мере, один многоатомный спирт и желатинирующее средство.
2. Композиция по п.1, дополнительно включающая агент, регулирующий рН.
3. Композиция по п.1, в которой указанный многоатомный спирт выбран из группы, состоящей из глицерина, алкиленгликоля, полиэтиленгликоля и их смесей.
4. Композиция по п.1, в которой указанное желатинирующее средство представляет собой гидроксипропилцеллюлозу.
5. Композиция по п.3, в которой указанный алкиленгликоль выбран из группы, состоящей из пропиленгликоля, бутиленгликоля и гексаленгликоля.
6. Композиция по п.4, в которой указанный полиэтиленгликоль выбран из группы, состоящей из полиэтиленгликоля 300, полиэтиленгликоля 400 и их смесей.
7. Композиция по п.1, в которой указанное желатинирующее средство представляет собой молочную кислоту.
8. Композиция по п.5, которая включает от около 75 до около 99 мас.% многоатомного спирта, от около 0,1 до около 4 мас.% гидроксипропилцеллюлозы и от около 0,1 до около 1 мас.% молочной кислоты.
9. Композиция по п.1, которая имеет вязкость от около 1000 до около 7000 сП.
10. Композиция по п.1, которая имеет вязкость от около 60000 до около 500000 сП.
11. Композиция по п.1, дополнительно включающая антимикробное средство.
12. Композиция по п.11, в которой указанное антимикробное средство представляет собой противогрибковое средство.
13. Композиция по п.11, в которой указанное антимикробное средство представляет собой антибактериальное средство.
14. Композиция по п.11, в которой указанное антимикробное средство представляет собой противовирусное средство.
15. Композиция по п.1, которая дополнительно включает средство, разрушающее сперматозоиды.
16. Композиция по п.1, которая дополнительно включает местный анестетик.
17. Способ лечения или предотвращения дисменореи, включающий внутривлагалищное нанесение композиции по п.1.
18. Композиция по п.1, причем температура указанной композиции увеличивается после контакта с влагой.
19. Композиция по п.7, рН которой доводят до диапазона от около 2 до около 6.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/137,509 | 2002-05-01 | ||
| US10/137509 | 2002-05-01 | ||
| US10/137,509 US7005408B2 (en) | 2002-05-01 | 2002-05-01 | Warming and nonirritating lubricant compositions and method of comparing irritation |
| US10/390,511 US7758887B2 (en) | 2002-05-01 | 2003-03-17 | Warming and nonirritating lubricant compositions and method of comparing irritation |
| US10/390511 | 2003-03-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2004131858A true RU2004131858A (ru) | 2005-06-10 |
| RU2288700C2 RU2288700C2 (ru) | 2006-12-10 |
Family
ID=29406252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004131858/15A RU2288700C2 (ru) | 2002-05-01 | 2003-05-01 | Согревающие и нераздражающие безводные смазывающие композиции |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1501478A1 (ru) |
| KR (1) | KR101046538B1 (ru) |
| CN (1) | CN1665484A (ru) |
| AU (1) | AU2003241338A1 (ru) |
| BR (1) | BRPI0309768B8 (ru) |
| CA (1) | CA2484329A1 (ru) |
| MX (1) | MXPA04010890A (ru) |
| NZ (1) | NZ536379A (ru) |
| RU (1) | RU2288700C2 (ru) |
| WO (1) | WO2003092652A1 (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060188528A1 (en) * | 2005-02-23 | 2006-08-24 | Ansell Healthcare Products Llc | Spreadable warming lubricant |
| US7709428B2 (en) * | 2005-02-23 | 2010-05-04 | Ansell Healthcare Products Llc | Thickened spreadable warming lubricant |
| US7851419B2 (en) * | 2005-09-12 | 2010-12-14 | Nawaz Ahmad | Substantially anhydrous sprayable personal lubricant |
| US7786055B2 (en) | 2006-04-13 | 2010-08-31 | Mcneil-Ppc, Inc. | Antioxidant compositions for reducing odor in warming lubricant compositions |
| US20070281008A1 (en) * | 2006-06-05 | 2007-12-06 | Lin Shun Y | Personal lubricant compositions and kits for providing personal lubrication |
| US8770201B2 (en) * | 2007-10-26 | 2014-07-08 | Glycobiosciences Inc. | Condom with multifunctional coating |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981686A (en) * | 1987-05-18 | 1991-01-01 | Hardy Robert E | Personal lubricant |
| CA1337279C (en) * | 1989-06-06 | 1995-10-10 | Robert J. Borgman | Intravaginal treatment of vaginal infections with buffered metronidazole compositions |
| FR2739558B1 (fr) * | 1995-10-05 | 1997-11-28 | Innothera Lab Sa | Forme galenique unitaire pour hormonotherapie locale de la secheresse vaginale |
| DE19781197D2 (de) * | 1996-10-31 | 2000-07-13 | Notax Holding Ges M B H Wien | Verwendung von Polyäthylenglykol-9-Nonylphenyläther |
| CA2404739C (en) * | 2001-07-25 | 2004-01-27 | Aceram Technologies Inc. | Improved ceramic components, ceramic component systems, and ceramic armour systems |
-
2003
- 2003-05-01 BR BRPI0309768A patent/BRPI0309768B8/pt not_active IP Right Cessation
- 2003-05-01 KR KR1020047017603A patent/KR101046538B1/ko active IP Right Grant
- 2003-05-01 EP EP03731070A patent/EP1501478A1/en not_active Withdrawn
- 2003-05-01 AU AU2003241338A patent/AU2003241338A1/en not_active Abandoned
- 2003-05-01 CA CA002484329A patent/CA2484329A1/en not_active Abandoned
- 2003-05-01 MX MXPA04010890A patent/MXPA04010890A/es active IP Right Grant
- 2003-05-01 WO PCT/US2003/013554 patent/WO2003092652A1/en active Application Filing
- 2003-05-01 NZ NZ536379A patent/NZ536379A/en not_active IP Right Cessation
- 2003-05-01 RU RU2004131858/15A patent/RU2288700C2/ru active
- 2003-05-01 CN CN038158752A patent/CN1665484A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003241338A1 (en) | 2003-11-17 |
| CA2484329A1 (en) | 2003-11-13 |
| KR101046538B1 (ko) | 2011-07-07 |
| BRPI0309768B8 (pt) | 2021-05-25 |
| MXPA04010890A (es) | 2005-07-14 |
| EP1501478A1 (en) | 2005-02-02 |
| BR0309768B1 (pt) | 2014-06-24 |
| CN1665484A (zh) | 2005-09-07 |
| KR20050062466A (ko) | 2005-06-23 |
| NZ536379A (en) | 2006-12-22 |
| WO2003092652A1 (en) | 2003-11-13 |
| BR0309768A (pt) | 2005-03-22 |
| RU2288700C2 (ru) | 2006-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD4A | Correction of name of patent owner | ||
| PC41 | Official registration of the transfer of exclusive right |
Effective date: 20141110 |
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| PC41 | Official registration of the transfer of exclusive right |
Effective date: 20190829 |