RS62034B1 - Kompozicije za lečenje raka - Google Patents

Kompozicije za lečenje raka

Info

Publication number
RS62034B1
RS62034B1 RS20210531A RSP20210531A RS62034B1 RS 62034 B1 RS62034 B1 RS 62034B1 RS 20210531 A RS20210531 A RS 20210531A RS P20210531 A RSP20210531 A RS P20210531A RS 62034 B1 RS62034 B1 RS 62034B1
Authority
RS
Serbia
Prior art keywords
cancer
day
hydroxylase
abiraterone acetate
compositions
Prior art date
Application number
RS20210531A
Other languages
English (en)
Serbian (sr)
Inventor
Alan H Auerbach
Arie S Belldegrun
Original Assignee
Janssen Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38916904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS62034(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Oncology Inc filed Critical Janssen Oncology Inc
Publication of RS62034B1 publication Critical patent/RS62034B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RS20210531A 2006-08-25 2007-08-23 Kompozicije za lečenje raka RS62034B1 (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92150606P 2006-08-25 2006-08-25
EP12160586.9A EP2478907B1 (en) 2006-08-25 2007-08-23 Compositions for treating cancer

Publications (1)

Publication Number Publication Date
RS62034B1 true RS62034B1 (sr) 2021-07-30

Family

ID=38916904

Family Applications (2)

Application Number Title Priority Date Filing Date
RS20210531A RS62034B1 (sr) 2006-08-25 2007-08-23 Kompozicije za lečenje raka
RS20130401A RS52956B (sr) 2006-08-25 2007-08-23 Kompozicije za tretman kancera

Family Applications After (1)

Application Number Title Priority Date Filing Date
RS20130401A RS52956B (sr) 2006-08-25 2007-08-23 Kompozicije za tretman kancera

Country Status (20)

Country Link
EP (3) EP3804730A1 (enExample)
JP (10) JP2010501575A (enExample)
KR (4) KR20180003636A (enExample)
CN (2) CN101528308A (enExample)
AU (6) AU2007287098C1 (enExample)
CA (1) CA2661422C (enExample)
CY (2) CY1115477T1 (enExample)
DK (2) DK2061561T3 (enExample)
ES (2) ES2869343T3 (enExample)
HR (2) HRP20130961T1 (enExample)
HU (1) HUE054495T2 (enExample)
IL (3) IL197211A0 (enExample)
LT (1) LT2478907T (enExample)
NO (2) NO20091190L (enExample)
NZ (1) NZ597830A (enExample)
PL (2) PL2478907T3 (enExample)
PT (2) PT2478907T (enExample)
RS (2) RS62034B1 (enExample)
SI (2) SI2478907T1 (enExample)
WO (1) WO2008024484A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010501575A (ja) * 2006-08-25 2010-01-21 クオウガル バイオテクノロジー,インコーポレイテッド 癌を治療するための方法及び組成物
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
WO2009009132A1 (en) * 2007-07-12 2009-01-15 Cougar Biotechnology, Inc. Use of 17alpha-hydroxylase/c17, 20-lyase inhibitors for the treatment of cancer
MX2010004405A (es) * 2007-10-29 2010-05-03 Takeda Pharmaceutical Derivados de pirrolo [1,2-c] imidazol para utilizarse en la profilaxis o tratamiento de cancer que es refractario a terapias cancerigenas conocidas.
CN102558274B (zh) * 2010-12-08 2014-10-15 深圳万乐药业有限公司 一种适合工业化生产醋酸阿比特龙的合成方法
CN102558275A (zh) * 2010-12-20 2012-07-11 天津药物研究院 α型多晶型醋酸阿比特龙结晶、其制备方法、用途和药物组合物
SG10201600077RA (en) 2011-01-11 2016-02-26 Glaxosmithkline Llc Combination
WO2012135759A1 (en) 2011-04-01 2012-10-04 Genentech, Inc. Combinations of akt inhibitor compounds and abiraterone, and methods of use
US20120295932A1 (en) * 2011-05-17 2012-11-22 Western Connecticut Health Network, Inc. Method for the treatment of cancer
CN103070828B (zh) * 2011-10-26 2016-01-27 山东新时代药业有限公司 一种含醋酸阿比特龙的固体分散体、片剂及其制备方法
CN102336801B (zh) * 2011-10-31 2013-05-15 南京卡文迪许生物工程技术有限公司 醋酸阿比特龙多晶型物和药用组合物
GB201207886D0 (en) * 2012-05-04 2012-06-20 Jagotec Ag Improvements in or relating to organic compounds
BR112014030099A2 (pt) * 2012-06-06 2017-06-27 Novartis Ag combinação de um inibidor 17-alfa-hidroxilase(c17,20-liase) e um inibidor pi-3 k específico para tratamento de uma doença de tumor
IL312316A (en) 2012-09-26 2024-06-01 Aragon Pharmaceuticals Inc Antiandrogens for the treatment of castration-resistant prostate cancer without metastases
CN103800296A (zh) * 2012-11-13 2014-05-21 重庆医药工业研究院有限责任公司 一种稳定的阿比特龙口服固体药物组合物及其制备方法
JOP20200097A1 (ar) * 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
US20150246060A1 (en) 2013-03-15 2015-09-03 Iceutica Inc. Abiraterone Acetate Formulation and Methods of Use
KR20160023641A (ko) * 2013-03-15 2016-03-03 아이슈티카 인코포레이티드 아비라테론 아세테이트 제제
CN108472242A (zh) * 2013-04-04 2018-08-31 埃克塞里艾克西斯公司 治疗癌症的药物组合
US20150157646A1 (en) 2013-09-27 2015-06-11 Iceutica Inc. Abiraterone Steroid Formulation
BR112016006970A2 (pt) * 2013-10-01 2017-08-01 Novartis Ag enzalutamida em combinação com afuresertib para o tratamento de câncer
CN109674801A (zh) * 2013-10-01 2019-04-26 诺华股份有限公司 组合
CN104546745A (zh) * 2013-10-14 2015-04-29 深圳海王药业有限公司 醋酸阿比特龙的片剂组合物及其制备工艺
EP3280448B1 (en) * 2015-04-10 2020-12-30 Capsugel Belgium NV Abiraterone acetate lipid formulations
IL322013A (en) 2016-07-29 2025-09-01 Janssen Pharmaceutica Nv Niraparib or its salts for use in the treatment of prostate cancer
JOP20190244A1 (ar) * 2017-04-13 2019-10-13 Janssen Pharmaceutica Nv تركيبة علاجية لسرطان البروستاتا
JOP20200076A1 (ar) 2017-10-16 2020-04-30 Aragon Pharmaceuticals Inc مضادات أندروجين لعلاج سرطان البروستاتا غير النقيلي المقاوم للاستئصال
CN109718198A (zh) * 2017-10-30 2019-05-07 浙江京新药业股份有限公司 一种治疗前列腺癌的注射剂及其制备方法
JP7644713B2 (ja) 2019-03-06 2025-03-12 プロペラ セラピューティクス インコーポレイテッド アビラテロンプロドラッグ
WO2021031991A1 (zh) * 2019-08-16 2021-02-25 中国科学院分子细胞科学卓越创新中心 治疗激素依赖性疾病及减少激素依赖性疾病患者药物耐受的组合物和方法
EP4135659A1 (en) * 2020-04-16 2023-02-22 Tavanta Therapeutics Hungary Incorporated Methods and compositions for treating prostate cancer
CN114560903B (zh) * 2022-03-09 2023-08-01 绍兴市上虞区武汉理工大学高等研究院 一种阿比特龙衍生物的制备方法及其细胞毒性评价
LU506495B1 (en) 2024-03-01 2025-09-01 Alfasan Nederland B V 17alpha-HYDROXYLASE/17,20-LYASE (CYP17A1) INHIBITORS FOR THE TREATMENT OF SPONTANEOUS HYPERADRENOCORTICISM IN DOGS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0633893T3 (da) 1992-03-31 2000-04-17 Btg Int Ltd 17-Substituerede steroider, der er nyttige ved cancerbehandling
US5604213A (en) 1992-03-31 1997-02-18 British Technology Group Limited 17-substituted steroids useful in cancer treatment
ES2300323T3 (es) * 2000-03-02 2008-06-16 Univ Pittsburgh Quimioterapia combinada.
WO2002053138A2 (en) * 2001-01-02 2002-07-11 Elisabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens
WO2004037269A1 (en) * 2002-10-23 2004-05-06 Pantarhei Bioscience B.V. Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy
EP1583539A2 (en) * 2003-01-13 2005-10-12 Cedars-Sinai Medical Center Paricalcitol as a chemotherapeutic agent
US20060030608A1 (en) 2004-08-04 2006-02-09 Boehringer Ingelheim Pharmaceuticals, Inc. Anti aromatase compounds pharmaceutical compositions and uses thereof
GB0418900D0 (en) * 2004-08-24 2004-09-29 Btg Int Ltd Novel salt forms
JP2010501575A (ja) * 2006-08-25 2010-01-21 クオウガル バイオテクノロジー,インコーポレイテッド 癌を治療するための方法及び組成物

Also Published As

Publication number Publication date
KR20200125776A (ko) 2020-11-04
RS52956B (sr) 2014-02-28
DK2478907T3 (da) 2021-05-25
JP6053279B2 (ja) 2016-12-27
JP2018065859A (ja) 2018-04-26
EP2478907B1 (en) 2021-04-14
JP2020114851A (ja) 2020-07-30
AU2015221447B2 (en) 2016-12-15
NZ597830A (en) 2013-02-22
AU2022206696A1 (en) 2022-08-11
AU2007287098C1 (en) 2018-03-15
SI2478907T1 (sl) 2021-08-31
AU2017201764A1 (en) 2017-04-06
EP3804730A1 (en) 2021-04-14
JP2017052791A (ja) 2017-03-16
AU2018271331A1 (en) 2018-12-20
NO20091190L (no) 2009-03-20
AU2021201649A1 (en) 2021-04-08
EP2061561B1 (en) 2013-07-10
JP6740497B2 (ja) 2020-08-12
PT2061561E (pt) 2013-10-09
ES2428634T3 (es) 2013-11-08
JP2010501575A (ja) 2010-01-21
JP6445123B2 (ja) 2018-12-26
CY1124221T1 (el) 2022-05-27
HK1131577A1 (en) 2010-01-29
JP2015110577A (ja) 2015-06-18
KR20150108946A (ko) 2015-09-30
SI2061561T1 (sl) 2013-11-29
AU2015221447B9 (en) 2017-07-20
JP2022185091A (ja) 2022-12-13
WO2008024484A1 (en) 2008-02-28
EP2478907A3 (en) 2012-08-01
IL227746A0 (en) 2013-09-30
CA2661422A1 (en) 2008-02-28
DK2061561T3 (da) 2013-10-07
CA2661422C (en) 2017-06-27
CY1115477T1 (el) 2017-01-04
CN101528308A (zh) 2009-09-09
HRP20130961T1 (hr) 2013-11-22
LT2478907T (lt) 2021-06-25
JP2012082215A (ja) 2012-04-26
HRP20210670T1 (hr) 2021-06-11
PL2061561T3 (pl) 2013-12-31
CN104306977A (zh) 2015-01-28
EP2061561A1 (en) 2009-05-27
AU2007287098B2 (en) 2013-08-15
IL257681A (en) 2018-04-30
PT2478907T (pt) 2021-05-26
JP2021038252A (ja) 2021-03-11
EP2478907A2 (en) 2012-07-25
NO20200775A1 (no) 2009-03-20
IL197211A0 (en) 2009-12-24
KR20180003636A (ko) 2018-01-09
AU2015221447A1 (en) 2015-09-17
JP2024164147A (ja) 2024-11-26
JP2019059750A (ja) 2019-04-18
AU2007287098A1 (en) 2008-02-28
HUE054495T2 (hu) 2021-09-28
ES2869343T3 (es) 2021-10-25
KR20090059126A (ko) 2009-06-10
PL2478907T3 (pl) 2021-10-25

Similar Documents

Publication Publication Date Title
RS62034B1 (sr) Kompozicije za lečenje raka
EP3638233B1 (en) Tinostamustine for use in treating ovarian cancer
CN101669941A (zh) 一种联合用药治疗恶性肿瘤的方法以及抗恶性肿瘤的药物
WO2018229130A1 (en) Compounds for treating tnbc
EP2670405B1 (en) Combinations comprising macitentan for the treatment of glioblastoma multiforme
JP2019513828A (ja) 改善された薬物動態を有するイソフラボノイド組成物
Girod et al. The COX inhibitors indomethacin and meloxicam exhibit anti-emetic activity against cisplatin-induced emesis in piglets
JP2006513223A (ja) p−アミノ安息香酸(PABA)によるメラニン形成及びメラノーマ転移の阻害
CN111386113A (zh) 包含lsz102和阿培利司的药物组合
US20220062294A1 (en) Pharmaceutical compositions of tetracyclic quinolone analogs and their salts
EP4232010A2 (en) Cancer therapy using a combination of cdk7 inhibitor with an anti-microtubule agent
HK1131577B (en) Compositions for treating cancer
ES2310182T3 (es) 7-hidroxiepiandrosterona con actividad neuroprotectora.
HK1173966B (en) Compositions for treating cancer
CN114569545B (zh) 一种稳定的米托蒽醌制剂
CN107007611A (zh) 醋酸诺美孕酮在制备治疗子宫内膜癌的药物中的应用
CN113950329A (zh) 多羟基化胆汁酸和法尼醇x受体激动剂的联合
TW200902028A (en) Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in BRCA mediated diseases
Landström et al. Effect of medroxyprogesterone acetate, alone or in combination with epirubicin hydrochloride, on the growth of the Dunning R3327H prostatic adenocarcinoma
US20230364053A1 (en) Pharmaceutical composition for treatment of prostate cancer or breast cancer
WO2023172909A1 (en) Compositions comprising anti-progestins and selective estrogen receptor modulators and methods of using the same
US20220354815A1 (en) Okn-007 as a therapeutic agent
Zelnak et al. Hormonal Therapy for Cancer
Kim et al. Hormonal Anticancer Drugs
CN120501842A (zh) 直肠肽联合五羟二苯基酮对肾脏纤维化的协同改善作用