RS61852B1 - Oblici soli (s)-hinuklidin-3-il (2-(2-(4-fluorofenil)tiazol-4-il)propan-2-il)karbamata - Google Patents

Oblici soli (s)-hinuklidin-3-il (2-(2-(4-fluorofenil)tiazol-4-il)propan-2-il)karbamata

Info

Publication number
RS61852B1
RS61852B1 RS20210607A RSP20210607A RS61852B1 RS 61852 B1 RS61852 B1 RS 61852B1 RS 20210607 A RS20210607 A RS 20210607A RS P20210607 A RSP20210607 A RS P20210607A RS 61852 B1 RS61852 B1 RS 61852B1
Authority
RS
Serbia
Prior art keywords
quinuclidin
thiazol
propan
fluorophenyl
carbamate
Prior art date
Application number
RS20210607A
Other languages
English (en)
Inventor
Craig Siegel
Jin Zhao
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50543351&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS61852(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of RS61852B1 publication Critical patent/RS61852B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RS20210607A 2013-03-15 2014-03-14 Oblici soli (s)-hinuklidin-3-il (2-(2-(4-fluorofenil)tiazol-4-il)propan-2-il)karbamata RS61852B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791706P 2013-03-15 2013-03-15
EP14718854.4A EP2970250B1 (en) 2013-03-15 2014-03-14 Salt forms of (s)-quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate
PCT/US2014/027081 WO2014152215A1 (en) 2013-03-15 2014-03-14 SALT FORMS OF (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate

Publications (1)

Publication Number Publication Date
RS61852B1 true RS61852B1 (sr) 2021-06-30

Family

ID=50543351

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20210607A RS61852B1 (sr) 2013-03-15 2014-03-14 Oblici soli (s)-hinuklidin-3-il (2-(2-(4-fluorofenil)tiazol-4-il)propan-2-il)karbamata

Country Status (34)

Country Link
US (1) US9518049B2 (sr)
EP (1) EP2970250B1 (sr)
JP (1) JP6438455B2 (sr)
KR (1) KR102302064B1 (sr)
CN (1) CN105189490A (sr)
AR (1) AR095435A1 (sr)
AU (1) AU2014240028B2 (sr)
BR (1) BR112015022907B1 (sr)
CA (1) CA2906691A1 (sr)
CL (1) CL2015002701A1 (sr)
DK (1) DK2970250T3 (sr)
EA (1) EA037527B1 (sr)
ES (1) ES2872326T3 (sr)
HK (1) HK1214821A1 (sr)
HR (1) HRP20210692T1 (sr)
HU (1) HUE054349T2 (sr)
IL (1) IL241229B (sr)
JO (1) JO3713B1 (sr)
LT (1) LT2970250T (sr)
MA (1) MA38488A1 (sr)
MX (1) MX370178B (sr)
MY (1) MY181766A (sr)
PH (1) PH12015502021A1 (sr)
PL (1) PL2970250T3 (sr)
PT (1) PT2970250T (sr)
RS (1) RS61852B1 (sr)
SA (1) SA515361078B1 (sr)
SG (1) SG11201507054YA (sr)
SI (1) SI2970250T1 (sr)
TN (1) TN2015000427A1 (sr)
TW (1) TWI713438B (sr)
UY (1) UY35439A (sr)
WO (1) WO2014152215A1 (sr)
ZA (1) ZA201506602B (sr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160361301A1 (en) * 2013-12-11 2016-12-15 Genzyme Corporation Glucosylceramide synthase inhibitors
US10519157B2 (en) * 2018-02-09 2019-12-31 X-Cutag Therapeutics, Inc. Deuterated compounds for treating Fabry, Gaucher, Parkinson's and related diseases and conditions, and compositions and methods thereof
WO2020163337A1 (en) 2019-02-04 2020-08-13 Genzyme Corporation Treatment of ciliopathies using inhibitors of glucosylceramide synthase (gcs)
WO2021156769A1 (en) * 2020-02-03 2021-08-12 Genzyme Corporation Methods for treating neurological symptoms associated with lysosomal storage diseases
BR112023000798A2 (pt) * 2020-07-24 2023-02-07 Genzyme Corp Composições farmacêuticas compreendendo venglustat
AU2021317180A1 (en) 2020-07-30 2023-03-23 Genzyme Corporation Methods for reducing glycosphingolipid concentration in brain tissue and methods of treatment of neurodegenerative diseases involving the same
WO2022215083A1 (en) * 2021-04-05 2022-10-13 Msn Laboratories Private Limited, R&D Center Solid state forms of (s)-quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl) carbamate or salts and process for its preparation thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236838A (en) 1988-12-23 1993-08-17 Genzyme Corporation Enzymatically active recombinant glucocerebrosidase
US5549892A (en) 1988-12-23 1996-08-27 Genzyme Corporation Enhanced in vivo uptake of glucocerebrosidase
US5272071A (en) 1989-12-22 1993-12-21 Applied Research Systems Ars Holding N.V. Method for the modification of the expression characteristics of an endogenous gene of a given cell line
US5968502A (en) 1991-11-05 1999-10-19 Transkaryotic Therapies, Inc. Protein production and protein delivery
DE69835367T2 (de) 1997-10-29 2007-08-02 Genzyme Corp., Framingham Gentherapie für gaucher-krankheit
GB0400812D0 (en) 2004-01-14 2004-02-18 Celltech R&D Ltd Novel compounds
WO2006053043A2 (en) 2004-11-10 2006-05-18 Genzyme Corporation Methods of treating diabetes mellitus
WO2010091104A1 (en) 2009-02-06 2010-08-12 Exelixis, Inc. Glucosylceramide synthase inhibitors
RU2569744C2 (ru) 2009-08-28 2015-11-27 Маунт Синай Скул Оф Медсин Ферментная заместительная терапия с увеличением дозы для лечения недостаточности кислой сфингомиелиназы
JP6117708B2 (ja) * 2011-03-18 2017-04-19 ジェンザイム・コーポレーション グルコシルセラミド合成酵素阻害剤

Also Published As

Publication number Publication date
DK2970250T3 (da) 2021-07-12
KR20150132333A (ko) 2015-11-25
AU2014240028A1 (en) 2015-10-15
EA201591706A1 (ru) 2016-02-29
SI2970250T1 (sl) 2021-06-30
UY35439A (es) 2014-10-31
CA2906691A1 (en) 2014-09-25
WO2014152215A1 (en) 2014-09-25
SG11201507054YA (en) 2015-10-29
TWI713438B (zh) 2020-12-21
NZ712659A (en) 2020-11-27
CN105189490A (zh) 2015-12-23
ES2872326T3 (es) 2021-11-02
MA38488A1 (fr) 2017-10-31
US9518049B2 (en) 2016-12-13
ZA201506602B (en) 2023-04-26
MX2015012295A (es) 2016-05-16
TN2015000427A1 (en) 2017-01-03
JP6438455B2 (ja) 2018-12-12
IL241229B (en) 2019-12-31
MY181766A (en) 2021-01-06
KR102302064B1 (ko) 2021-09-13
MX370178B (es) 2019-12-04
JO3713B1 (ar) 2021-01-31
BR112015022907B1 (pt) 2022-07-12
US20160039805A1 (en) 2016-02-11
HUE054349T2 (hu) 2021-09-28
EA037527B1 (ru) 2021-04-08
BR112015022907A8 (pt) 2019-11-26
JP2016513679A (ja) 2016-05-16
SA515361078B1 (ar) 2018-06-14
EP2970250B1 (en) 2021-04-21
HRP20210692T1 (hr) 2021-06-11
IL241229A0 (en) 2015-11-30
AU2014240028B2 (en) 2018-08-02
PT2970250T (pt) 2021-05-07
BR112015022907A2 (pt) 2017-07-18
PL2970250T3 (pl) 2021-12-06
HK1214821A1 (zh) 2016-08-05
PH12015502021A1 (en) 2016-01-11
TW201502127A (zh) 2015-01-16
EP2970250A1 (en) 2016-01-20
LT2970250T (lt) 2021-05-10
CL2015002701A1 (es) 2016-03-18
AR095435A1 (es) 2015-10-14

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