RS61193B1 - So agonista opijatnog receptora (mor), kristalni oblik i fumaratne soli iste i postupak za njihovo dobijanje - Google Patents
So agonista opijatnog receptora (mor), kristalni oblik i fumaratne soli iste i postupak za njihovo dobijanjeInfo
- Publication number
- RS61193B1 RS61193B1 RS20201514A RSP20201514A RS61193B1 RS 61193 B1 RS61193 B1 RS 61193B1 RS 20201514 A RS20201514 A RS 20201514A RS P20201514 A RSP20201514 A RS P20201514A RS 61193 B1 RS61193 B1 RS 61193B1
- Authority
- RS
- Serbia
- Prior art keywords
- salt
- mor
- preparation
- crystal form
- opioid receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710242119 | 2017-04-14 | ||
| EP18784878.3A EP3610875B1 (en) | 2017-04-14 | 2018-04-13 | Opioid receptor (mor) agonist salt, fumarate salt i crystal form thereof and preparation method thereof |
| PCT/CN2018/082935 WO2018188643A1 (zh) | 2017-04-14 | 2018-04-13 | 一种阿片样物质受体(mor)激动剂的盐、其富马酸盐i晶型及制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS61193B1 true RS61193B1 (sr) | 2021-01-29 |
Family
ID=63792318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20201514A RS61193B1 (sr) | 2017-04-14 | 2018-04-13 | So agonista opijatnog receptora (mor), kristalni oblik i fumaratne soli iste i postupak za njihovo dobijanje |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US11014914B2 (sr) |
| EP (1) | EP3610875B1 (sr) |
| JP (1) | JP7153030B6 (sr) |
| KR (1) | KR20190140962A (sr) |
| CN (1) | CN110049980B (sr) |
| AU (1) | AU2018251119B2 (sr) |
| BR (1) | BR112019021447A2 (sr) |
| CA (1) | CA3057383A1 (sr) |
| CY (1) | CY1124063T1 (sr) |
| DK (1) | DK3610875T3 (sr) |
| ES (1) | ES2828636T3 (sr) |
| HR (1) | HRP20210022T1 (sr) |
| HU (1) | HUE053244T2 (sr) |
| LT (1) | LT3610875T (sr) |
| MX (1) | MX2019012251A (sr) |
| MY (1) | MY196571A (sr) |
| PL (1) | PL3610875T3 (sr) |
| PT (1) | PT3610875T (sr) |
| RS (1) | RS61193B1 (sr) |
| SI (1) | SI3610875T1 (sr) |
| TW (1) | TWI682929B (sr) |
| UA (1) | UA124400C2 (sr) |
| WO (1) | WO2018188643A1 (sr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3610874A4 (en) * | 2017-04-14 | 2021-01-06 | Jiangsu Hengrui Medicine Co., Ltd. | PHARMACEUTICAL COMPOSITION CONTAINING A MOR AGONIST AND A KOR AGONIST, AND ITS USES |
| LT3610875T (lt) * | 2017-04-14 | 2020-11-25 | Jiangsu Hengrui Medicine Co., Ltd. | Opioido (mor) agonisto druska, jo fumarato druskos i kristalinė forma ir jos gavimo būdas |
| WO2019205983A1 (zh) * | 2018-04-28 | 2019-10-31 | 四川科伦博泰生物医药股份有限公司 | 氧杂螺环类化合物及其制备方法和用途 |
| WO2020073985A1 (zh) * | 2018-10-12 | 2020-04-16 | 江苏恒瑞医药股份有限公司 | 一种阿片样物质受体(mor)激动剂的结晶形式及制备方法 |
| CN112638906B (zh) * | 2018-10-12 | 2022-05-27 | 江苏恒瑞医药股份有限公司 | 一种阿片样物质受体(mor)激动剂的结晶形式及制备方法 |
| CN111662284B (zh) * | 2019-03-06 | 2021-08-10 | 上海海雁医药科技有限公司 | 双杂环取代的氧杂螺环衍生物、其制法与医药上的用途 |
| KR20210113824A (ko) | 2020-03-09 | 2021-09-17 | 건국대학교 산학협력단 | 뮤 오피오이드 수용체의 활성화제를 유효성분으로 포함하는 기분 장애의 예방용 조성물 |
| WO2023284788A1 (zh) * | 2021-07-13 | 2023-01-19 | 上海海雁医药科技有限公司 | Mor受体激动剂的药学上可接受的盐、其多晶型物及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2857549T3 (es) | 2011-03-23 | 2021-09-29 | Trevena Inc | Ligandos de receptores de opioides y métodos para utilizar y obtener los mismos |
| JP6824502B2 (ja) | 2015-10-15 | 2021-02-03 | ジエンス ヘンルイ メデイシンカンパニー リミテッドＪｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．，Ｌｔｄ． | オキサスピロ誘導体、その製造方法、及び医薬におけるその適用 |
| LT3610875T (lt) * | 2017-04-14 | 2020-11-25 | Jiangsu Hengrui Medicine Co., Ltd. | Opioido (mor) agonisto druska, jo fumarato druskos i kristalinė forma ir jos gavimo būdas |
-
2018
- 2018-04-13 LT LTEP18784878.3T patent/LT3610875T/lt unknown
- 2018-04-13 US US16/499,453 patent/US11014914B2/en active Active
- 2018-04-13 DK DK18784878.3T patent/DK3610875T3/da active
- 2018-04-13 SI SI201830176T patent/SI3610875T1/sl unknown
- 2018-04-13 PL PL18784878T patent/PL3610875T3/pl unknown
- 2018-04-13 HU HUE18784878A patent/HUE053244T2/hu unknown
- 2018-04-13 RS RS20201514A patent/RS61193B1/sr unknown
- 2018-04-13 CN CN201880004976.2A patent/CN110049980B/zh active Active
- 2018-04-13 PT PT187848783T patent/PT3610875T/pt unknown
- 2018-04-13 MX MX2019012251A patent/MX2019012251A/es unknown
- 2018-04-13 EP EP18784878.3A patent/EP3610875B1/en active Active
- 2018-04-13 BR BR112019021447A patent/BR112019021447A2/pt active Search and Examination
- 2018-04-13 KR KR1020197033496A patent/KR20190140962A/ko active IP Right Grant
- 2018-04-13 AU AU2018251119A patent/AU2018251119B2/en active Active
- 2018-04-13 TW TW107112721A patent/TWI682929B/zh active
- 2018-04-13 WO PCT/CN2018/082935 patent/WO2018188643A1/zh active Application Filing
- 2018-04-13 UA UAA201911049A patent/UA124400C2/uk unknown
- 2018-04-13 ES ES18784878T patent/ES2828636T3/es active Active
- 2018-04-13 JP JP2019555801A patent/JP7153030B6/ja active Active
- 2018-04-13 CA CA3057383A patent/CA3057383A1/en active Pending
-
2019
- 2019-10-03 MY MYPI2019005849A patent/MY196571A/en unknown
-
2020
- 2020-10-22 CY CY20201101000T patent/CY1124063T1/el unknown
-
2021
- 2021-01-07 US US17/143,549 patent/US20210130332A1/en not_active Abandoned
- 2021-01-07 HR HRP20210022TT patent/HRP20210022T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018251119B2 (en) | 2021-07-29 |
| TWI682929B (zh) | 2020-01-21 |
| ES2828636T3 (es) | 2021-05-27 |
| CY1124063T1 (el) | 2022-03-24 |
| TW201837033A (zh) | 2018-10-16 |
| DK3610875T3 (da) | 2020-12-21 |
| JP7153030B6 (ja) | 2023-07-24 |
| KR20190140962A (ko) | 2019-12-20 |
| PL3610875T3 (pl) | 2021-04-19 |
| SI3610875T1 (sl) | 2021-02-26 |
| WO2018188643A1 (zh) | 2018-10-18 |
| PT3610875T (pt) | 2020-11-25 |
| CN110049980B (zh) | 2020-10-20 |
| US20200048229A1 (en) | 2020-02-13 |
| EP3610875B1 (en) | 2020-10-07 |
| AU2018251119A1 (en) | 2019-11-07 |
| MY196571A (en) | 2023-04-19 |
| CA3057383A1 (en) | 2018-10-18 |
| HUE053244T2 (hu) | 2021-06-28 |
| RU2019136088A3 (sr) | 2021-06-16 |
| HRP20210022T1 (hr) | 2021-03-05 |
| US20210130332A1 (en) | 2021-05-06 |
| BR112019021447A2 (pt) | 2020-05-05 |
| EP3610875A1 (en) | 2020-02-19 |
| JP7153030B2 (ja) | 2022-10-13 |
| UA124400C2 (uk) | 2021-09-08 |
| MX2019012251A (es) | 2019-11-28 |
| JP2020516642A (ja) | 2020-06-11 |
| LT3610875T (lt) | 2020-11-25 |
| CN110049980A (zh) | 2019-07-23 |
| US11014914B2 (en) | 2021-05-25 |
| RU2019136088A (ru) | 2021-05-14 |
| EP3610875A4 (en) | 2020-02-19 |
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