SG11201608372PA - Irinotecan hydrochloride composite phospholipid composition, preparation method and use thereof - Google Patents
Irinotecan hydrochloride composite phospholipid composition, preparation method and use thereofInfo
- Publication number
- SG11201608372PA SG11201608372PA SG11201608372PA SG11201608372PA SG11201608372PA SG 11201608372P A SG11201608372P A SG 11201608372PA SG 11201608372P A SG11201608372P A SG 11201608372PA SG 11201608372P A SG11201608372P A SG 11201608372PA SG 11201608372P A SG11201608372P A SG 11201608372PA
- Authority
- SG
- Singapore
- Prior art keywords
- preparation
- irinotecan hydrochloride
- phospholipid composition
- composite phospholipid
- hydrochloride composite
- Prior art date
Links
- 239000002131 composite material Substances 0.000 title 1
- 229960000779 irinotecan hydrochloride Drugs 0.000 title 1
- GURKHSYORGJETM-WAQYZQTGSA-N irinotecan hydrochloride (anhydrous) Chemical compound Cl.C1=C2C(CC)=C3CN(C(C4=C([C@@](C(=O)OC4)(O)CC)C=4)=O)C=4C3=NC2=CC=C1OC(=O)N(CC1)CCC1N1CCCCC1 GURKHSYORGJETM-WAQYZQTGSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000003904 phospholipids Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410085842.1A CN104906586A (en) | 2014-03-10 | 2014-03-10 | Irinotecan hydrochloride composite phospholipid composition, preparation method and applications thereof |
| PCT/CN2015/073761 WO2015135441A1 (en) | 2014-03-10 | 2015-03-06 | Irinotecan hydrochloride composite phospholipid composition, preparation method and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201608372PA true SG11201608372PA (en) | 2016-11-29 |
Family
ID=54070926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201608372PA SG11201608372PA (en) | 2014-03-10 | 2015-03-06 | Irinotecan hydrochloride composite phospholipid composition, preparation method and use thereof |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20170087146A1 (en) |
| CN (1) | CN104906586A (en) |
| AU (1) | AU2015230539B2 (en) |
| GB (1) | GB2538683A (en) |
| SG (1) | SG11201608372PA (en) |
| WO (1) | WO2015135441A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017110772A1 (en) * | 2015-12-21 | 2017-06-29 | 富士フイルム株式会社 | Liposome and liposome composition |
| CN105534906A (en) * | 2016-01-06 | 2016-05-04 | 青岛辰达生物科技有限公司 | Irinotecan hydrochloride lipidosome and preparation method thereof |
| CN107456456A (en) * | 2016-06-03 | 2017-12-12 | 江苏恒瑞医药股份有限公司 | The purposes of Irinotecan or its officinal salt in the medicine for preparing treatment breast cancer |
| CN108567742B (en) * | 2017-03-14 | 2021-05-18 | 中国科学院上海药物研究所 | SN38 lipid composition, preparation method and application thereof |
| CN106821987B (en) * | 2017-03-16 | 2021-03-02 | 四川大学 | Liposome carrying phenol hydroxyl group-containing insoluble drug, and preparation method and application thereof |
| CN107115300A (en) * | 2017-05-04 | 2017-09-01 | 方达医药技术（苏州）有限公司 | A kind of application process of tangential flow systems in ammonium sulphate gradient prepares liposome |
| WO2019023873A1 (en) * | 2017-07-31 | 2019-02-07 | 江苏竞诺择生物医药科技有限公司 | Nano-lipid microparticle composition and pharmaceutical composition for treating hematopoietic system proliferative diseases |
| CN108159401B (en) * | 2018-03-16 | 2021-05-07 | 昆明积大制药股份有限公司 | Apelin liposome and preparation method thereof |
| CN111388368A (en) * | 2020-03-29 | 2020-07-10 | 杭州百芮生物科技有限公司 | Novel nano liposome coated tranexamic acid composition and preparation method thereof |
| CN113694069B (en) * | 2021-08-04 | 2022-11-01 | 贵州医科大学附属医院 | Preparation method of compound liposome carrying evodiamine and chloroquine phosphate together |
| CN115054700A (en) * | 2022-04-29 | 2022-09-16 | 潍坊医学院 | Targeted liposome carrying irinotecan hydrochloride and capecitabine together, and preparation method and application thereof |
| WO2024199424A1 (en) * | 2023-03-30 | 2024-10-03 | 上海济煜医药科技有限公司 | Phospholipid composition, preparation method therefor and use of nitrogen-containing compound |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE68968T1 (en) * | 1985-11-22 | 1991-11-15 | Takeda Chemical Industries Ltd | LIPOSOME COMPOSITION. |
| US7485320B2 (en) * | 2000-09-25 | 2009-02-03 | Industrial Technology Research Institute | Liposome for incorporating large amounts of hydrophobic substances |
| JP4885715B2 (en) * | 2004-06-01 | 2012-02-29 | テルモ株式会社 | Irinotecan formulation |
| JP2009513621A (en) * | 2005-10-26 | 2009-04-02 | イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム | Method for preparing liposomes and use thereof |
| CN1994279A (en) * | 2006-12-31 | 2007-07-11 | 西安力邦医药科技有限责任公司 | Preparation process of irinotecan hydrochloride liposome for injection |
| CN102271659B (en) * | 2009-12-03 | 2013-09-18 | 江苏恒瑞医药股份有限公司 | Liposome of irinotecan or its hydrochloride and preparation method thereof |
| CN102188378B (en) * | 2010-03-18 | 2014-07-09 | 浙江海正药业股份有限公司 | Preparation method of liposome for coating and carrying water soluble drugs |
| CN101953792B (en) * | 2010-09-06 | 2011-12-28 | 中华人民共和国卫生部肝胆肠外科研究中心 | Irinotecan nano circulating liposome and preparation method thereof |
| CN102935066B (en) * | 2011-08-16 | 2014-09-17 | 齐鲁制药有限公司 | Irinotecan liposome preparation and preparation method thereof |
-
2014
- 2014-03-10 CN CN201410085842.1A patent/CN104906586A/en active Pending
-
2015
- 2015-03-06 AU AU2015230539A patent/AU2015230539B2/en not_active Ceased
- 2015-03-06 US US15/124,626 patent/US20170087146A1/en not_active Abandoned
- 2015-03-06 WO PCT/CN2015/073761 patent/WO2015135441A1/en active Application Filing
- 2015-03-06 GB GB1616625.8A patent/GB2538683A/en not_active Withdrawn
- 2015-03-06 SG SG11201608372PA patent/SG11201608372PA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015230539A1 (en) | 2016-11-03 |
| GB2538683A (en) | 2016-11-23 |
| US20170087146A1 (en) | 2017-03-30 |
| GB2538683A8 (en) | 2016-11-30 |
| AU2015230539A8 (en) | 2016-12-01 |
| WO2015135441A1 (en) | 2015-09-17 |
| AU2015230539B2 (en) | 2017-12-21 |
| GB201616625D0 (en) | 2016-11-16 |
| CN104906586A (en) | 2015-09-16 |
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