RS60596B1 - Kompozicije za poboljšanje ćelijske vijabilnosti i postupci za njihovu upotrebu - Google Patents

Kompozicije za poboljšanje ćelijske vijabilnosti i postupci za njihovu upotrebu

Info

Publication number
RS60596B1
RS60596B1 RS20200676A RSP20200676A RS60596B1 RS 60596 B1 RS60596 B1 RS 60596B1 RS 20200676 A RS20200676 A RS 20200676A RS P20200676 A RSP20200676 A RS P20200676A RS 60596 B1 RS60596 B1 RS 60596B1
Authority
RS
Serbia
Prior art keywords
compositions
methods
cell viability
improving cell
improving
Prior art date
Application number
RS20200676A
Other languages
English (en)
Inventor
Joshua B Cohen
Justin Klee
Original Assignee
Amylyx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51569584&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS60596(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amylyx Pharmaceuticals Inc filed Critical Amylyx Pharmaceuticals Inc
Publication of RS60596B1 publication Critical patent/RS60596B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
RS20200676A 2013-03-24 2014-02-24 Kompozicije za poboljšanje ćelijske vijabilnosti i postupci za njihovu upotrebu RS60596B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361804690P 2013-03-24 2013-03-24
US14/140,083 US9872865B2 (en) 2013-03-24 2013-12-24 Compositions for improving cell viability and methods of use thereof
EP14775675.3A EP2978419B1 (en) 2013-03-24 2014-02-24 Compositions for improving cell viability and methods of use thereof
PCT/US2014/018040 WO2014158547A1 (en) 2013-03-24 2014-02-24 Compositions for improving cell viability and methods of use thereof

Publications (1)

Publication Number Publication Date
RS60596B1 true RS60596B1 (sr) 2020-08-31

Family

ID=51569584

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20200676A RS60596B1 (sr) 2013-03-24 2014-02-24 Kompozicije za poboljšanje ćelijske vijabilnosti i postupci za njihovu upotrebu

Country Status (20)

Country Link
US (7) US9872865B2 (sr)
EP (2) EP3750531A1 (sr)
JP (5) JP6495237B2 (sr)
KR (6) KR20230164242A (sr)
CN (3) CN105050593B (sr)
AU (4) AU2014242123B2 (sr)
CA (1) CA2908683A1 (sr)
CY (1) CY1123092T1 (sr)
DK (1) DK2978419T3 (sr)
ES (1) ES2796250T3 (sr)
HK (1) HK1216851A1 (sr)
HR (1) HRP20200990T1 (sr)
HU (1) HUE051105T2 (sr)
LT (1) LT2978419T (sr)
ME (1) ME03747B (sr)
PL (1) PL2978419T3 (sr)
PT (1) PT2978419T (sr)
RS (1) RS60596B1 (sr)
SI (1) SI2978419T1 (sr)
WO (1) WO2014158547A1 (sr)

Families Citing this family (30)

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US9872865B2 (en) 2013-03-24 2018-01-23 Amylyx Pharmaceuticals Inc. Compositions for improving cell viability and methods of use thereof
US10934244B2 (en) * 2015-06-15 2021-03-02 Nmd Pharma A/S Compounds for use in treating neuromuscular disorders
KR101743960B1 (ko) * 2015-07-06 2017-06-08 서울대학교산학협력단 G단백질 결합형 수용체19 작용제를 유효성분으로 함유하는 알츠하이머 질환 또는 치매를 예방, 치료 또는 지연하기 위한 약학적 조성물
EP3347486A4 (en) * 2015-09-09 2019-06-19 The Trustees of Columbia University in the City of New York REDUCTION OF ER-MAM-LOCALIZED APP-C99 AND METHOD FOR THE TREATMENT OF ALZHEIMER DISEASE
JP2019526612A (ja) * 2016-09-12 2019-09-19 スティーブン・ホフマン 認知症を治療するための組成物
US20210293794A1 (en) * 2017-02-24 2021-09-23 University Of Hawii Cancer Center Metabolic biomarkers for the identification and characterization of alzheimers disease
US11147788B2 (en) 2017-12-14 2021-10-19 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11730714B2 (en) 2017-12-14 2023-08-22 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11591284B2 (en) 2017-12-14 2023-02-28 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
CN113164421A (zh) * 2018-12-18 2021-07-23 参天制药株式会社 含有4-苯基丁酸的老视的治疗或预防剂
CA3140042A1 (en) 2019-05-14 2020-11-19 Tyme, Inc. Compositions and methods for treating cancer
US11583542B2 (en) * 2019-12-16 2023-02-21 Amylyx Pharmaceuticals, Inc. Compositions of bile acids and phenylbutyrate compounds
MX2022007276A (es) * 2019-12-16 2023-04-25 Amylyx Pharmaceuticals Inc Tratamiento de la esclerosis amiotrofica lateral y enfermedades relacionadas.
IL295562A (en) * 2020-02-13 2022-10-01 Prilenia Neurotherapeutics Ltd Treatment of muscular dystrophy (ALS) by combining pridopidine and another active substance
US10905698B1 (en) * 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections
WO2022188029A1 (zh) * 2021-03-09 2022-09-15 兆科药业（广州）有限公司 一种含牛磺熊去氧胆酸、苯丁酸钠的复方散剂/颗粒剂、制备方法、用途以及其药物组合物
WO2022191296A1 (ja) * 2021-03-10 2022-09-15 昭和電工マテリアルズ株式会社 培地組成物、細胞培養物の製造方法、及び細胞懸濁物
CN113332267A (zh) * 2021-03-31 2021-09-03 中山大学孙逸仙纪念医院 苯丁酸钠在制备预防或治疗帕金森病的药物中的应用
CN113349300A (zh) * 2021-06-07 2021-09-07 湖南农业大学 4-苯基丁酸在制备猪肠道保健产品中的应用
WO2023081482A1 (en) * 2021-11-08 2023-05-11 Amylyx Pharmaceuticals, Inc. Combination of turso and sodium phenyl butyrate for the treatment of neurodegenerative diseases
WO2023102149A1 (en) * 2021-12-02 2023-06-08 MarvelBiome, Inc. Methods and uses of microbiome compositions, components, or metabolites for treating vagus nerve associated diseases, disorders, and conditions
US20230277630A1 (en) 2022-03-02 2023-09-07 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
US20230364110A1 (en) * 2022-05-12 2023-11-16 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
US20230372263A1 (en) 2022-05-17 2023-11-23 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
WO2024015286A1 (en) * 2022-07-11 2024-01-18 AI Therapeutics, Inc. Apilimod combination therapy
WO2024015281A1 (en) * 2022-07-11 2024-01-18 AI Therapeutics, Inc. Apilimod combination therapy
US20240100069A1 (en) 2022-09-07 2024-03-28 Amylyx Pharmaceuticals, Inc. Methods and Compositions for Treating Amyotrophic Lateral Sclerosis
US20240139211A1 (en) 2022-09-29 2024-05-02 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
WO2024095118A1 (en) 2022-10-31 2024-05-10 Novartis Ag Dosing regimen of a csf-1r inhibitor for use in the treatment of amyotrophic lateral sclerosis
WO2024105168A1 (en) 2022-11-18 2024-05-23 Inflectis Bioscience Novel combinations useful for the treatments of als

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US20030225031A1 (en) 2002-05-21 2003-12-04 Quay Steven C. Administration of acetylcholinesterase inhibitors to the cerebral spinal fluid
WO2004096123A2 (en) 2003-04-02 2004-11-11 Regents Of The University Of Minnesota Methods of promoting cell viability
JP2008518935A (ja) * 2004-11-01 2008-06-05 セオ ホン ユー 筋萎縮性側索硬化症の神経退行を減少させるための方法及び組成物
CN101048164B (zh) 2004-11-01 2012-05-09 柳署弘 降低肌萎缩性侧索硬化中神经变性的组合物
US20060135612A1 (en) 2004-12-17 2006-06-22 U.S. Department Of Veterans Affairs Method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as amyotrophic lateral sclerosis (ALS), by using a HDAC inhibiting agent
EP1871385A1 (en) 2005-02-10 2008-01-02 Regents Of The University Of Minnesota Methods for treating visual disorders
CA2679608A1 (en) 2006-03-22 2007-10-04 President And Fellows Of Harvard College Methods and compositions for treating hypercholesterolemia and atherosclerosis
US7737175B2 (en) 2007-06-01 2010-06-15 Duke University Methods and compositions for regulating HDAC4 activity
ES2332687B1 (es) 2008-03-13 2011-01-10 Proyecto De Biomedicina Cima, S.L. Nuevos usos de 4pba y sus sales farmaceuticamente aceptables.
CA2723833A1 (en) 2008-05-12 2009-11-19 Umut Ozcan Methods and compositions for the treatment of obesity
US20110142799A1 (en) 2008-06-23 2011-06-16 President And Fellows Of Harvard College Modulation of neurodegenerative disease by modulating xbp-1 activity
US20120157419A1 (en) 2009-02-02 2012-06-21 Tuvia Gilat Methods and compositions for treating alzheimer's disease
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WO2013142490A2 (en) 2012-03-20 2013-09-26 Metselex, Inc. Tauroursodeoxycholic acid attenuates or abolishes formation and deposition of amyloid-b peptide
US9872865B2 (en) 2013-03-24 2018-01-23 Amylyx Pharmaceuticals Inc. Compositions for improving cell viability and methods of use thereof
DK3016654T3 (en) 2013-07-01 2018-11-05 Bruschettini Srl TAUROURODEOXYCHOLIC ACID (TUDCA) FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS
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Also Published As

Publication number Publication date
JP2019123721A (ja) 2019-07-25
KR102460746B1 (ko) 2022-10-31
ME03747B (me) 2021-04-20
EP2978419A4 (en) 2016-11-16
US20200230156A1 (en) 2020-07-23
CN109999043A (zh) 2019-07-12
CN105050593A (zh) 2015-11-11
CN110787169B (zh) 2023-10-20
AU2019200658B2 (en) 2020-12-24
HUE051105T2 (hu) 2021-03-01
KR102223250B1 (ko) 2021-03-08
SI2978419T1 (sl) 2020-11-30
CA2908683A1 (en) 2014-10-02
AU2014242123B2 (en) 2018-11-01
US20190255072A1 (en) 2019-08-22
US20180098999A1 (en) 2018-04-12
WO2014158547A1 (en) 2014-10-02
US10857162B2 (en) 2020-12-08
PL2978419T3 (pl) 2020-10-19
EP2978419B1 (en) 2020-04-15
JP2022122929A (ja) 2022-08-23
US20200171052A1 (en) 2020-06-04
KR20210156312A (ko) 2021-12-24
CN105050593B (zh) 2019-12-03
KR20220066178A (ko) 2022-05-23
JP6495237B2 (ja) 2019-04-03
EP2978419A1 (en) 2016-02-03
US20220110948A1 (en) 2022-04-14
US20140288030A1 (en) 2014-09-25
CY1123092T1 (el) 2021-10-29
CN110787169A (zh) 2020-02-14
JP2023085274A (ja) 2023-06-20
KR102607635B1 (ko) 2023-11-30
KR20230164242A (ko) 2023-12-01
DK2978419T3 (da) 2020-05-04
AU2019200658A1 (en) 2019-02-21
US20220160733A1 (en) 2022-05-26
KR20150135471A (ko) 2015-12-02
AU2021201770A1 (en) 2021-04-15
US11071742B2 (en) 2021-07-27
KR102396714B1 (ko) 2022-05-12
PT2978419T (pt) 2020-06-19
LT2978419T (lt) 2020-08-10
JP7242945B2 (ja) 2023-03-20
US9872865B2 (en) 2018-01-23
JP6766198B2 (ja) 2020-10-07
AU2021201770B2 (en) 2022-05-26
HK1216851A1 (zh) 2016-12-09
ES2796250T3 (es) 2020-11-26
EP3750531A1 (en) 2020-12-16
AU2014242123A1 (en) 2015-09-17
CN109999043B (zh) 2023-01-20
JP7080944B2 (ja) 2022-06-06
JP2016515575A (ja) 2016-05-30
KR20210025134A (ko) 2021-03-08
US10251896B2 (en) 2019-04-09
AU2022221410A1 (en) 2022-09-15
JP2021008473A (ja) 2021-01-28
KR20220148337A (ko) 2022-11-04
HRP20200990T1 (hr) 2020-10-16

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