RS58696B1 - Novo antitelo protiv humanog tslp receptora - Google Patents

Novo antitelo protiv humanog tslp receptora

Info

Publication number
RS58696B1
RS58696B1 RS20190580A RSP20190580A RS58696B1 RS 58696 B1 RS58696 B1 RS 58696B1 RS 20190580 A RS20190580 A RS 20190580A RS P20190580 A RSP20190580 A RS P20190580A RS 58696 B1 RS58696 B1 RS 58696B1
Authority
RS
Serbia
Prior art keywords
receptor antibody
novel anti
human tslp
tslp receptor
human
Prior art date
Application number
RS20190580A
Other languages
English (en)
Inventor
Hiromu Sato
Daisuke Yamajuku
Kazunori Arai
Mako Ogino
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of RS58696B1 publication Critical patent/RS58696B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
RS20190580A 2013-08-09 2014-08-08 Novo antitelo protiv humanog tslp receptora RS58696B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013165676 2013-08-09
PCT/JP2014/071008 WO2015020193A1 (ja) 2013-08-09 2014-08-08 新規抗ヒトtslp受容体抗体
EP14833804.9A EP3031913B1 (en) 2013-08-09 2014-08-08 Novel anti-human tslp receptor antibody

Publications (1)

Publication Number Publication Date
RS58696B1 true RS58696B1 (sr) 2019-06-28

Family

ID=52461517

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20190580A RS58696B1 (sr) 2013-08-09 2014-08-08 Novo antitelo protiv humanog tslp receptora

Country Status (29)

Country Link
US (2) US9328171B2 (sr)
EP (1) EP3031913B1 (sr)
JP (1) JP6380394B2 (sr)
KR (1) KR102260680B1 (sr)
AR (1) AR097293A1 (sr)
AU (1) AU2014303356B2 (sr)
BR (1) BR112016002743B1 (sr)
CA (1) CA2920484C (sr)
CY (1) CY1121678T1 (sr)
DK (1) DK3031913T3 (sr)
ES (1) ES2730978T3 (sr)
HK (1) HK1223123A1 (sr)
HR (1) HRP20190752T1 (sr)
HU (1) HUE043111T2 (sr)
IL (1) IL243851B (sr)
LT (1) LT3031913T (sr)
MX (1) MX369208B (sr)
MY (1) MY177098A (sr)
PH (1) PH12016500237A1 (sr)
PL (1) PL3031913T3 (sr)
PT (1) PT3031913T (sr)
RS (1) RS58696B1 (sr)
RU (1) RU2689528C2 (sr)
SG (1) SG11201600935SA (sr)
SI (1) SI3031913T1 (sr)
TR (1) TR201906969T4 (sr)
TW (1) TWI635097B (sr)
UA (1) UA119328C2 (sr)
WO (1) WO2015020193A1 (sr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6897570B2 (ja) * 2015-12-18 2021-06-30 アステラス製薬株式会社 抗ヒトtslp受容体抗体含有医薬組成物
CA3183367A1 (en) 2020-07-06 2022-01-13 Gevorg GRIGORYAN Antigen binding molecules targeting sars-cov-2
EP4204446A1 (en) 2020-08-26 2023-07-05 Flagship Pioneering Innovations VI, LLC Antigen binding molecules targeting sars-cov-2
CN114853888B (zh) * 2021-02-05 2023-11-03 上海洛启生物医药技术有限公司 抗tslp纳米抗体及其应用
CN113069543B (zh) * 2021-06-07 2021-08-06 迈威(上海)生物科技股份有限公司 包含抗胸腺基质淋巴细胞生成素的单克隆抗体的液体组合物
WO2023028612A2 (en) * 2021-08-27 2023-03-02 Board Of Regents, The University Of Texas System Anti-tslpr (crlf2) antibodies
CN114028562B (zh) * 2021-11-01 2022-05-24 江苏荃信生物医药股份有限公司 包含抗人胸腺基质淋巴细胞生成素(tslp)单克隆抗体的液体制剂
CN116217725B (zh) * 2021-12-02 2023-09-22 北京东方百泰生物科技股份有限公司 一种抗tslp单克隆抗体的纯化方法
CN117209604B (zh) * 2021-12-02 2024-03-22 北京东方百泰生物科技股份有限公司 一种抗tslp的单克隆抗体、其抗原结合片段及其应用
US11993644B2 (en) 2022-05-06 2024-05-28 Generate Biomedicines, Inc. Antigen binding molecules targeting SARS-CoV-2
WO2024102675A1 (en) * 2022-11-07 2024-05-16 Upstream Bio, Inc. Pharmaceutical compositions comprising anti-human tslp receptor antibodies and methods of using the same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
DE69433422T2 (de) 1993-03-11 2004-09-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Monoklonaler anti-hiv antikörper
MXPA02012747A (es) * 2000-06-28 2003-09-25 Amgen Inc Moleculas del receptor de linfopoietina estromica timica y sus usos.
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
US20050249712A1 (en) * 2004-03-23 2005-11-10 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services Methods for use of TSLP and agonists and antagonists thereof
RU2486202C2 (ru) * 2006-01-13 2013-06-27 Айрм Ллк Антитела к рецептору тимусного стромального лимфопоэтина
JP2010512744A (ja) * 2006-12-14 2010-04-30 シェーリング−プラウ・リミテッド イヌの胸腺間質リンホポエチンタンパク質およびその使用
WO2008155365A1 (en) * 2007-06-20 2008-12-24 Irm Llc Methods and compositions for treating allergic diseases
JP2011511638A (ja) * 2008-02-07 2011-04-14 シェーリング コーポレイション 抗tslpr抗体の設計製作
AR082163A1 (es) 2010-07-15 2012-11-14 Hoffmann La Roche Anticuerpos especificamente ligantes del tslpr humano y metodos de utilizacion de los mismos
WO2012015696A1 (en) * 2010-07-26 2012-02-02 Baylor Research Institute Thymic stromal lymphopoietin (tslp) and ox40 ligand in cancer
US9732151B2 (en) * 2011-11-03 2017-08-15 Merck Sharp & Dohme Corp. Biomarkers for TSLP treatment

Also Published As

Publication number Publication date
EP3031913B1 (en) 2019-04-17
HK1223123A1 (zh) 2017-07-21
SG11201600935SA (en) 2016-03-30
TR201906969T4 (tr) 2019-06-21
DK3031913T3 (da) 2019-05-20
RU2016107814A3 (sr) 2018-06-28
CA2920484A1 (en) 2015-02-12
HRP20190752T1 (hr) 2019-06-14
EP3031913A1 (en) 2016-06-15
HUE043111T2 (hu) 2019-08-28
AU2014303356A2 (en) 2017-02-02
US20160046720A1 (en) 2016-02-18
US20160208005A1 (en) 2016-07-21
CY1121678T1 (el) 2020-07-31
TW201536806A (zh) 2015-10-01
PT3031913T (pt) 2019-05-31
AU2014303356A1 (en) 2016-02-18
JPWO2015020193A1 (ja) 2017-03-02
KR20160035080A (ko) 2016-03-30
UA119328C2 (uk) 2019-06-10
WO2015020193A1 (ja) 2015-02-12
TWI635097B (zh) 2018-09-11
KR102260680B1 (ko) 2021-06-07
IL243851B (en) 2019-11-28
LT3031913T (lt) 2019-05-27
RU2016107814A (ru) 2017-09-14
RU2689528C2 (ru) 2019-05-28
JP6380394B2 (ja) 2018-08-29
IL243851A0 (en) 2016-04-21
MX2016001796A (es) 2016-04-15
US9328171B2 (en) 2016-05-03
US9908941B2 (en) 2018-03-06
BR112016002743B1 (pt) 2020-12-08
SI3031913T1 (sl) 2019-06-28
ES2730978T3 (es) 2019-11-13
PH12016500237B1 (en) 2016-05-02
AU2014303356B2 (en) 2020-01-02
PH12016500237A1 (en) 2016-05-02
MX369208B (es) 2019-10-31
PL3031913T3 (pl) 2019-08-30
AR097293A1 (es) 2016-03-02
BR112016002743A2 (pt) 2017-11-21
EP3031913A4 (en) 2017-03-22
CA2920484C (en) 2021-03-30
MY177098A (en) 2020-09-05

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