RS56904B1 - Humanizovna il-25 antitela - Google Patents

Humanizovna il-25 antitela

Info

Publication number
RS56904B1
RS56904B1 RS20180208A RSP20180208A RS56904B1 RS 56904 B1 RS56904 B1 RS 56904B1 RS 20180208 A RS20180208 A RS 20180208A RS P20180208 A RSP20180208 A RS P20180208A RS 56904 B1 RS56904 B1 RS 56904B1
Authority
RS
Serbia
Prior art keywords
humanized
antibodies
Prior art date
Application number
RS20180208A
Other languages
English (en)
Inventor
Juan Carlos Almagro
Patrick Branigan
Colleen Kane
William Strohl
Susann Taudte
Mark Tornetta
John Wheeler
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of RS56904B1 publication Critical patent/RS56904B1/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
RS20180208A 2010-03-30 2011-03-30 Humanizovna il-25 antitela RS56904B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34145810P 2010-03-30 2010-03-30
US31926010P 2010-03-31 2010-03-31
PCT/US2011/030469 WO2011123507A1 (en) 2010-03-30 2011-03-30 Humanized il-25 antibodies
EP11763357.8A EP2552961B1 (en) 2010-03-30 2011-03-30 Humanized il-25 antibodies

Publications (1)

Publication Number Publication Date
RS56904B1 true RS56904B1 (sr) 2018-05-31

Family

ID=44712602

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20180208A RS56904B1 (sr) 2010-03-30 2011-03-30 Humanizovna il-25 antitela

Country Status (34)

Country Link
US (1) US8785605B2 (sr)
EP (1) EP2552961B1 (sr)
JP (1) JP5887337B2 (sr)
KR (1) KR101830181B1 (sr)
CN (1) CN103097416B (sr)
AU (1) AU2011235232B2 (sr)
BR (1) BR112012024786A2 (sr)
CA (1) CA2795043C (sr)
CL (1) CL2012002745A1 (sr)
CR (1) CR20120553A (sr)
CY (1) CY1120468T1 (sr)
DK (1) DK2552961T3 (sr)
EA (1) EA031203B1 (sr)
EC (1) ECSP12012202A (sr)
ES (1) ES2656336T3 (sr)
GT (1) GT201200266A (sr)
HK (1) HK1185088A1 (sr)
HR (1) HRP20180340T1 (sr)
HU (1) HUE036157T2 (sr)
IL (1) IL222015B (sr)
LT (1) LT2552961T (sr)
MX (1) MX2012011479A (sr)
MY (1) MY163133A (sr)
NI (1) NI201200144A (sr)
NO (1) NO2552961T3 (sr)
NZ (1) NZ602720A (sr)
PE (1) PE20130192A1 (sr)
PL (1) PL2552961T3 (sr)
PT (1) PT2552961T (sr)
RS (1) RS56904B1 (sr)
SG (1) SG184195A1 (sr)
SI (1) SI2552961T1 (sr)
WO (1) WO2011123507A1 (sr)
ZA (1) ZA201208136B (sr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0817891D0 (en) * 2008-09-30 2008-11-05 Medical Res Council Antibodies against il-25
US9212227B2 (en) 2012-04-30 2015-12-15 Janssen Biotech, Inc. ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
CN103792375B (zh) * 2014-01-29 2017-07-07 华中科技大学同济医学院附属同济医院 外周血白细胞介素25水平在哮喘分型中的应用及分型方法
KR102576368B1 (ko) 2014-09-23 2023-09-08 리제너론 파마슈티칼스 인코포레이티드 항-il-25 항체 및 그것의 사용
KR102477922B1 (ko) * 2016-03-16 2022-12-14 아베오미 코포레이션 Il-25에 대한 중화 모노클로날 항체 및 그의 용도
WO2018018082A1 (en) 2016-07-26 2018-02-01 The Australian National University Immunostimulatory compositions and uses therefor
WO2020102935A1 (en) * 2018-11-19 2020-05-28 Suzhou Kanova Biopharmaceutical Co., Ltd. Anti-il-25 antibodies and use thereof
GB202018015D0 (en) * 2020-11-16 2020-12-30 Res & Innovation Uk Composition and methods for the treatment of intestinal cancer

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Also Published As

Publication number Publication date
KR101830181B1 (ko) 2018-02-20
BR112012024786A2 (pt) 2017-01-10
SG184195A1 (en) 2012-11-29
NZ602720A (en) 2014-10-31
PT2552961T (pt) 2018-03-01
CY1120468T1 (el) 2019-07-10
HK1185088A1 (zh) 2014-02-07
EP2552961A1 (en) 2013-02-06
MX2012011479A (es) 2012-12-17
CN103097416B (zh) 2015-09-09
HUE036157T2 (hu) 2018-06-28
ECSP12012202A (es) 2012-10-30
PE20130192A1 (es) 2013-02-27
LT2552961T (lt) 2018-02-12
CR20120553A (es) 2013-05-15
ES2656336T3 (es) 2018-02-26
DK2552961T3 (en) 2018-03-05
CN103097416A (zh) 2013-05-08
JP5887337B2 (ja) 2016-03-16
WO2011123507A1 (en) 2011-10-06
SI2552961T1 (en) 2018-02-28
CA2795043A1 (en) 2011-10-06
CA2795043C (en) 2019-04-23
EP2552961B1 (en) 2017-12-20
EP2552961A4 (en) 2013-10-30
EA201290977A1 (ru) 2013-04-30
AU2011235232A1 (en) 2012-10-25
HRP20180340T1 (hr) 2018-03-23
US20110318353A1 (en) 2011-12-29
MY163133A (en) 2017-08-15
AU2011235232B2 (en) 2015-05-21
EA031203B1 (ru) 2018-11-30
GT201200266A (es) 2014-03-14
IL222015B (en) 2020-08-31
US8785605B2 (en) 2014-07-22
NO2552961T3 (sr) 2018-05-19
ZA201208136B (en) 2014-03-26
JP2013523132A (ja) 2013-06-17
PL2552961T3 (pl) 2018-04-30
NI201200144A (es) 2013-04-19
CL2012002745A1 (es) 2013-01-25
KR20130009999A (ko) 2013-01-24

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