RS56667B1 - Kombinovane formulacije darunavira - Google Patents

Kombinovane formulacije darunavira

Info

Publication number
RS56667B1
RS56667B1 RS20171244A RSP20171244A RS56667B1 RS 56667 B1 RS56667 B1 RS 56667B1 RS 20171244 A RS20171244 A RS 20171244A RS P20171244 A RSP20171244 A RS P20171244A RS 56667 B1 RS56667 B1 RS 56667B1
Authority
RS
Serbia
Prior art keywords
darunavir
combination formulations
formulations
combination
darunavir combination
Prior art date
Application number
RS20171244A
Other languages
English (en)
Inventor
Urbain Alfons C Delaet
Philip Erna H Heyns
Eugeen Maria Jozef Jans
Roel Jos M Mertens
Der Avoort Geert Van
Original Assignee
Janssen Sciences Ireland Uc
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc, Gilead Sciences Inc filed Critical Janssen Sciences Ireland Uc
Publication of RS56667B1 publication Critical patent/RS56667B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20171244A 2011-07-07 2012-07-06 Kombinovane formulacije darunavira RS56667B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11173067 2011-07-07
PCT/EP2012/063249 WO2013004818A1 (en) 2011-07-07 2012-07-06 Darunavir combination formulations
EP12738060.8A EP2729130B1 (en) 2011-07-07 2012-07-06 Darunavir combination formulations

Publications (1)

Publication Number Publication Date
RS56667B1 true RS56667B1 (sr) 2018-03-30

Family

ID=46551505

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20171244A RS56667B1 (sr) 2011-07-07 2012-07-06 Kombinovane formulacije darunavira

Country Status (23)

Country Link
US (3) US20140142070A1 (sr)
EP (1) EP2729130B1 (sr)
JP (1) JP6122427B2 (sr)
KR (1) KR102058097B1 (sr)
CN (1) CN103826616B (sr)
AU (1) AU2012280198B2 (sr)
BR (1) BR112014000290B1 (sr)
CA (1) CA2838659C (sr)
CY (1) CY1121999T1 (sr)
DK (1) DK2729130T3 (sr)
EA (1) EA026587B1 (sr)
ES (1) ES2651212T3 (sr)
HR (1) HRP20171889T1 (sr)
HU (1) HUE035241T2 (sr)
IL (1) IL229933A (sr)
LT (1) LT2729130T (sr)
MX (1) MX343689B (sr)
NO (1) NO2729130T3 (sr)
PL (1) PL2729130T3 (sr)
PT (1) PT2729130T (sr)
RS (1) RS56667B1 (sr)
SI (1) SI2729130T1 (sr)
WO (1) WO2013004818A1 (sr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE035241T2 (en) 2011-07-07 2018-05-02 Janssen Sciences Ireland Uc Darunavir combination products
EP2819644A1 (en) * 2012-03-01 2015-01-07 Gilead Sciences, Inc. Spray dried formulations
PT3608325T (pt) 2012-12-21 2022-10-17 Gilead Sciences Inc Compostos carbamoílpiridona policíclicos e sua utilização farmacêutica
PL3346995T3 (pl) 2015-11-09 2020-03-31 Gilead Sciences, Inc. Kompozycje terapeutyczne do leczenia ludzkiego wirusa niedoboru odporności
WO2018029566A1 (en) * 2016-08-08 2018-02-15 Hetero Labs Limited A high drug loaded tablet composition for treating hiv
WO2018029565A1 (en) 2016-08-08 2018-02-15 Hetero Labs Limited A multi-class anti-retroviral composition
BR112019002132A2 (pt) 2016-08-08 2019-05-14 Hetero Labs Limited composições anti-retrovirais
WO2018064071A1 (en) * 2016-09-27 2018-04-05 Gilead Sciences, Inc. Therapeutic compositions for treatment of human immunodeficiency virus
EP3654951A1 (en) 2017-07-20 2020-05-27 Janssen Sciences Ireland Unlimited Company Compositions comprising darunavir, cobicistat, emtricitabine and tenofovir alafenamide for use in the treatment of hiv
WO2020064980A1 (en) 2018-09-28 2020-04-02 Janssen Sciences Ireland Unlimited Company Methods of treating and preventing neuropsychiatric and/or neurocognitive complications in patients infected with hiv
WO2021180963A1 (en) 2020-03-13 2021-09-16 Janssen Sciences Ireland Unlimited Company A protease inhibitor regimen for treating subjects infected with hiv

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968942A (en) 1992-08-25 1999-10-19 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
AU7669794A (en) 1993-08-24 1995-03-21 G.D. Searle & Co. Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors
PT1088098E (pt) 1998-06-23 2011-05-25 Univ Illinois Medicamento para tratar mam?feros infectados com hiv
TWI286476B (en) 2001-12-12 2007-09-11 Tibotec Pharm Ltd Combination of cytochrome P450 dependent protease inhibitors
MXPA04011427A (es) 2002-05-16 2005-02-17 Tibotec Pharm Ltd Formas seudopolimorficas de un inhibidor de proteasa del virus de inmunodeficiencia adquirida.
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
MX2008015365A (es) 2006-05-30 2008-12-16 Janssen Pharmaceutica Nv Compuestos de piridil amida sustituidos como moduladores del receptor h3 de la histamina.
US20080039428A1 (en) * 2006-06-29 2008-02-14 Panacos Pharmaceuticals, Inc. Antiretroviral combination therapy
KR20140004808A (ko) 2006-07-07 2014-01-13 길리애드 사이언시즈, 인코포레이티드 치료제의 약동학 특성의 모듈레이터
US20080113021A1 (en) * 2006-10-25 2008-05-15 Robert Shen Ibuprofen composition
PL2487161T3 (pl) 2007-02-23 2017-03-31 Gilead Sciences, Inc. Modulatory farmakokinetycznych właściwości środków terapeutycznych
CA2689330A1 (en) * 2007-06-25 2008-12-31 Tibotec Pharmaceuticals Combination formulations
AR069539A1 (es) * 2007-07-25 2010-02-03 Tibotec Pharm Ltd Avances respecto de las formulaciones de comprimidos contra el vih
AU2008326561B2 (en) 2007-11-20 2013-12-05 Janssen Pharmaceutica N.V. Cycloalkyloxy-and heterocycloalky-loxypyridine compounds as modulators of the histamine H3 receptor
PA8809601A1 (es) * 2007-12-24 2009-07-23 Cipla Ltd Combinación anti-retroviral
SG190618A1 (en) * 2008-05-02 2013-06-28 Gilead Sciences Inc The use of solid carrier particles to improve the processability of a pharmaceutical agent
HUE025822T2 (en) * 2009-02-06 2016-04-28 Gilead Sciences Inc Dual layer tablets containing Elvitegravir, Cobicistat, Emtricitabine and Tenofovir
PL2477992T3 (pl) * 2009-09-17 2017-07-31 Mylan Laboratories Limited Proces przygotowania Darunawiru i jego amorficznych postaci
WO2011141921A1 (en) 2010-05-10 2011-11-17 Hetero Research Foundation Darunavir compositions
EP2729128B1 (en) 2011-07-07 2016-07-27 Janssen Sciences Ireland UC Darunavir formulations
HUE035241T2 (en) 2011-07-07 2018-05-02 Janssen Sciences Ireland Uc Darunavir combination products
WO2013115916A1 (en) 2012-02-03 2013-08-08 Gilead Sciences, Inc. Combination therapy comprising gs-7340 and cobicistat for use in the treatment of viral infections
US20170348334A1 (en) 2015-01-03 2017-12-07 Mylan Laboratories Limited Processes for the preparation of amorphous tenofovir alafenamide hemifumarate and a premix thereof

Also Published As

Publication number Publication date
US20230302024A1 (en) 2023-09-28
US20200093840A1 (en) 2020-03-26
AU2012280198A8 (en) 2014-01-16
KR102058097B1 (ko) 2019-12-20
HUE035241T2 (en) 2018-05-02
EA201490222A1 (ru) 2014-04-30
HRP20171889T1 (hr) 2018-01-12
AU2012280198B2 (en) 2016-12-22
EP2729130B1 (en) 2017-09-06
EP2729130A1 (en) 2014-05-14
CA2838659A1 (en) 2013-01-10
JP2014520787A (ja) 2014-08-25
CN103826616A (zh) 2014-05-28
US20140142070A1 (en) 2014-05-22
NO2729130T3 (sr) 2018-02-03
DK2729130T3 (en) 2017-12-11
PT2729130T (pt) 2017-12-13
AU2012280198A1 (en) 2014-01-09
BR112014000290A2 (pt) 2017-02-07
MX2013015199A (es) 2014-09-01
CA2838659C (en) 2020-02-18
IL229933A (en) 2017-09-28
SI2729130T1 (en) 2018-03-30
WO2013004818A1 (en) 2013-01-10
US11654150B2 (en) 2023-05-23
CN103826616B (zh) 2016-08-10
JP6122427B2 (ja) 2017-04-26
ES2651212T3 (es) 2018-01-25
PL2729130T3 (pl) 2018-02-28
LT2729130T (lt) 2018-01-10
CY1121999T1 (el) 2020-07-31
MX343689B (es) 2016-11-16
EA026587B1 (ru) 2017-04-28
BR112014000290B1 (pt) 2022-05-10
KR20140068845A (ko) 2014-06-09

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