RS56667B1 - Kombinovane formulacije darunavira - Google Patents

Kombinovane formulacije darunavira

Info

Publication number
RS56667B1
RS56667B1 RS20171244A RSP20171244A RS56667B1 RS 56667 B1 RS56667 B1 RS 56667B1 RS 20171244 A RS20171244 A RS 20171244A RS P20171244 A RSP20171244 A RS P20171244A RS 56667 B1 RS56667 B1 RS 56667B1
Authority
RS
Serbia
Prior art keywords
darunavir
combination formulations
formulations
combination
darunavir combination
Prior art date
Application number
RS20171244A
Other languages
English (en)
Serbian (sr)
Inventor
Urbain Alfons C Delaet
Philip Erna H Heyns
Eugeen Maria Jozef Jans
Roel Jos M Mertens
Der Avoort Geert Van
Original Assignee
Janssen Sciences Ireland Uc
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc, Gilead Sciences Inc filed Critical Janssen Sciences Ireland Uc
Publication of RS56667B1 publication Critical patent/RS56667B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20171244A 2011-07-07 2012-07-06 Kombinovane formulacije darunavira RS56667B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11173067 2011-07-07
PCT/EP2012/063249 WO2013004818A1 (en) 2011-07-07 2012-07-06 Darunavir combination formulations
EP12738060.8A EP2729130B1 (en) 2011-07-07 2012-07-06 Darunavir combination formulations

Publications (1)

Publication Number Publication Date
RS56667B1 true RS56667B1 (sr) 2018-03-30

Family

ID=46551505

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20171244A RS56667B1 (sr) 2011-07-07 2012-07-06 Kombinovane formulacije darunavira

Country Status (23)

Country Link
US (3) US20140142070A1 (US20070167479A1-20070719-C00034.png)
EP (1) EP2729130B1 (US20070167479A1-20070719-C00034.png)
JP (1) JP6122427B2 (US20070167479A1-20070719-C00034.png)
KR (1) KR102058097B1 (US20070167479A1-20070719-C00034.png)
CN (1) CN103826616B (US20070167479A1-20070719-C00034.png)
AU (1) AU2012280198B2 (US20070167479A1-20070719-C00034.png)
BR (1) BR112014000290B1 (US20070167479A1-20070719-C00034.png)
CA (1) CA2838659C (US20070167479A1-20070719-C00034.png)
CY (1) CY1121999T1 (US20070167479A1-20070719-C00034.png)
DK (1) DK2729130T3 (US20070167479A1-20070719-C00034.png)
EA (1) EA026587B1 (US20070167479A1-20070719-C00034.png)
ES (1) ES2651212T3 (US20070167479A1-20070719-C00034.png)
HR (1) HRP20171889T1 (US20070167479A1-20070719-C00034.png)
HU (1) HUE035241T2 (US20070167479A1-20070719-C00034.png)
IL (1) IL229933A (US20070167479A1-20070719-C00034.png)
LT (1) LT2729130T (US20070167479A1-20070719-C00034.png)
MX (1) MX343689B (US20070167479A1-20070719-C00034.png)
NO (1) NO2729130T3 (US20070167479A1-20070719-C00034.png)
PL (1) PL2729130T3 (US20070167479A1-20070719-C00034.png)
PT (1) PT2729130T (US20070167479A1-20070719-C00034.png)
RS (1) RS56667B1 (US20070167479A1-20070719-C00034.png)
SI (1) SI2729130T1 (US20070167479A1-20070719-C00034.png)
WO (1) WO2013004818A1 (US20070167479A1-20070719-C00034.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS56667B1 (sr) 2011-07-07 2018-03-30 Janssen Sciences Ireland Uc Kombinovane formulacije darunavira
JP2015508822A (ja) * 2012-03-01 2015-03-23 ギリアード サイエンシーズ, インコーポレイテッド 噴霧乾燥製剤
KR102527797B1 (ko) 2012-12-21 2023-05-03 길리애드 사이언시즈, 인코포레이티드 폴리시클릭-카르바모일피리돈 화합물 및 그의 제약 용도
TWI737647B (zh) 2015-11-09 2021-09-01 美商基利科學股份有限公司 用於治療人類免疫缺乏病毒之治療組合物
US20190175509A1 (en) * 2016-08-08 2019-06-13 Hetero Labs Limited High Drug Loaded Tablet Composition for Treating HIV
US11045423B2 (en) 2016-08-08 2021-06-29 Hetero Labs Limited Anti-retroviral compositions
US20190175511A1 (en) * 2016-08-08 2019-06-13 Hetero Labs Limited A Multi-Class Anti-Retroviral Composition
US20180085387A1 (en) * 2016-09-27 2018-03-29 Gilead Sciences, Inc. Therapeutic compositions for treatment of human immunodeficiency virus
MA49635A (fr) 2017-07-20 2020-05-27 Gilead Sciences Inc Compositions comprenant du darunavir, du cobicistat, de l'emtricitabine et du ténofovir alafénamide pour une utilisation dans le traitement du vih
US20200101093A1 (en) 2018-09-28 2020-04-02 Janssen Sciences Ireland Unlimited Company Methods of Treating and Preventing Neuropsychiatric and/or Neurocognitive Complications in Patients Infected with HIV
US20210290590A1 (en) 2020-03-13 2021-09-23 Janssen Sciences Ireland Unlimited Company Methods of treating subjects infected with hiv

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
WO1995006030A1 (en) 1993-08-24 1995-03-02 G.D. Searle & Co. Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors
US5968942A (en) 1992-08-25 1999-10-19 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
CA2336160C (en) 1998-06-23 2015-02-17 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Use of compounds for treating hiv
AR037797A1 (es) 2001-12-12 2004-12-01 Tibotec Pharm Ltd Combinacion de inhibidores de proteasa dependientes del citocromo p450
EA007120B8 (ru) 2002-05-16 2012-03-30 Тиботек Фармасьютикалз Лтд. Псевдополиморфные формы ингибитора вич-протеазы
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
AU2007256931B2 (en) 2006-05-30 2013-01-24 Janssen Pharmaceutica N.V. Substituted pyridyl amide compounds as modulators of the histamine H3 receptor
US20080039428A1 (en) * 2006-06-29 2008-02-14 Panacos Pharmaceuticals, Inc. Antiretroviral combination therapy
EP3696171A1 (en) 2006-07-07 2020-08-19 Gilead Sciences, Inc. Modulators of pharmacokinetic properties of therapeutics
CN101528205A (zh) * 2006-10-25 2009-09-09 麦克内尔-Ppc股份有限公司 布洛芬组合物
ES2603617T3 (es) 2007-02-23 2017-02-28 Gilead Sciences, Inc. Moduladores de propiedades farmacocinéticas de la terapéutica
BRPI0812964A2 (pt) * 2007-06-25 2014-12-16 Tibotec Pharm Ltd Forma de dosagem farmacêutica oral sólida
AR069539A1 (es) * 2007-07-25 2010-02-03 Tibotec Pharm Ltd Avances respecto de las formulaciones de comprimidos contra el vih
NZ584998A (en) 2007-11-20 2012-08-31 Janssen Pharmaceutica Nv Cycloalkyloxy-and heterocycloalkyloxypyridine compounds as modulators of the histamine h3 receptor
GT200800303A (es) * 2007-12-24 2009-09-18 Combinacion anti-retroviral
KR101784647B1 (ko) * 2008-05-02 2017-10-11 길리애드 사이언시즈, 인코포레이티드 제약 제제의 가공성 향상을 위한 고체 담체 입자의 용도
AP3250A (en) * 2009-02-06 2015-05-31 Gilead Sciences Inc Tablets for combination therapy
ES2619562T3 (es) * 2009-09-17 2017-06-26 Mylan Laboratories Limited Procesos para la preparación de darunavir y su forma amorfa
WO2011141921A1 (en) 2010-05-10 2011-11-17 Hetero Research Foundation Darunavir compositions
US20140142174A1 (en) 2011-07-07 2014-05-22 Urbain Alfons C. Delaet Darunavir formulations
RS56667B1 (sr) 2011-07-07 2018-03-30 Janssen Sciences Ireland Uc Kombinovane formulacije darunavira
WO2013115916A1 (en) 2012-02-03 2013-08-08 Gilead Sciences, Inc. Combination therapy comprising gs-7340 and cobicistat for use in the treatment of viral infections
EP3240793A1 (en) 2015-01-03 2017-11-08 Mylan Laboratories Ltd. Processes for the preparation of amorphous tenofovir alafenamide hemifumarate and a premix thereof

Also Published As

Publication number Publication date
EA201490222A1 (ru) 2014-04-30
MX343689B (es) 2016-11-16
AU2012280198A1 (en) 2014-01-09
HUE035241T2 (en) 2018-05-02
CN103826616A (zh) 2014-05-28
US20230302024A1 (en) 2023-09-28
EP2729130A1 (en) 2014-05-14
AU2012280198B2 (en) 2016-12-22
BR112014000290A2 (pt) 2017-02-07
EP2729130B1 (en) 2017-09-06
KR102058097B1 (ko) 2019-12-20
CY1121999T1 (el) 2020-07-31
MX2013015199A (es) 2014-09-01
PL2729130T3 (pl) 2018-02-28
CN103826616B (zh) 2016-08-10
US11654150B2 (en) 2023-05-23
ES2651212T3 (es) 2018-01-25
IL229933A (en) 2017-09-28
CA2838659C (en) 2020-02-18
BR112014000290B1 (pt) 2022-05-10
SI2729130T1 (en) 2018-03-30
WO2013004818A1 (en) 2013-01-10
HRP20171889T1 (hr) 2018-01-12
CA2838659A1 (en) 2013-01-10
US20200093840A1 (en) 2020-03-26
JP2014520787A (ja) 2014-08-25
KR20140068845A (ko) 2014-06-09
US20140142070A1 (en) 2014-05-22
JP6122427B2 (ja) 2017-04-26
PT2729130T (pt) 2017-12-13
DK2729130T3 (en) 2017-12-11
AU2012280198A8 (en) 2014-01-16
NO2729130T3 (US20070167479A1-20070719-C00034.png) 2018-02-03
EA026587B1 (ru) 2017-04-28
LT2729130T (lt) 2018-01-10

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