RS55158B1 - Jedinjenja akrilamida kao ligandi histaminskog h3 receptora - Google Patents

Jedinjenja akrilamida kao ligandi histaminskog h3 receptora

Info

Publication number
RS55158B1
RS55158B1 RS20160783A RSP20160783A RS55158B1 RS 55158 B1 RS55158 B1 RS 55158B1 RS 20160783 A RS20160783 A RS 20160783A RS P20160783 A RSP20160783 A RS P20160783A RS 55158 B1 RS55158 B1 RS 55158B1
Authority
RS
Serbia
Prior art keywords
histamine
receptor ligands
acrylamide compounds
acrylamide
compounds
Prior art date
Application number
RS20160783A
Other languages
English (en)
Inventor
Ramakrishna Nirogi
Anil Karbhari Shinde
Adi Reddy Dwarampudi
Venkateswarlu Jasti
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Publication of RS55158B1 publication Critical patent/RS55158B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02Dicarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RS20160783A 2012-08-23 2012-12-05 Jedinjenja akrilamida kao ligandi histaminskog h3 receptora RS55158B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3464CH2012 2012-08-23
EP12844650.7A EP2888243B1 (en) 2012-08-23 2012-12-05 Acrylamide compounds as histamine h3 receptor ligands
PCT/IN2012/000796 WO2014030170A1 (en) 2012-08-23 2012-12-05 Acrylamide compounds as histamine h3 receptor ligands

Publications (1)

Publication Number Publication Date
RS55158B1 true RS55158B1 (sr) 2017-01-31

Family

ID=54187093

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20160783A RS55158B1 (sr) 2012-08-23 2012-12-05 Jedinjenja akrilamida kao ligandi histaminskog h3 receptora

Country Status (27)

Country Link
US (1) US9328092B2 (sr)
EP (1) EP2888243B1 (sr)
JP (1) JP5981654B2 (sr)
KR (1) KR101707343B1 (sr)
CN (1) CN104540812B (sr)
AP (1) AP2014008139A0 (sr)
AU (1) AU2012388383C1 (sr)
BR (1) BR112015001524B1 (sr)
CA (1) CA2878217C (sr)
CY (1) CY1118035T1 (sr)
DK (1) DK2888243T3 (sr)
EA (1) EA025136B1 (sr)
ES (1) ES2592819T3 (sr)
HK (1) HK1204620A1 (sr)
HR (1) HRP20161167T1 (sr)
HU (1) HUE030901T2 (sr)
IL (1) IL236437A (sr)
LT (1) LT2888243T (sr)
ME (1) ME02519B (sr)
MX (1) MX360001B (sr)
PL (1) PL2888243T3 (sr)
PT (1) PT2888243T (sr)
RS (1) RS55158B1 (sr)
SG (1) SG11201408423XA (sr)
SI (1) SI2888243T1 (sr)
SM (1) SMT201600336B (sr)
WO (1) WO2014030170A1 (sr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11313246B2 (en) * 2016-11-30 2022-04-26 General Electric Company Gas turbine engine wash system
WO2022113008A1 (en) 2020-11-27 2022-06-02 Richter Gedeon Nyrt. Histamine h3 receptor antagonists/inverse agonists for the treatment of autism spectrum disorder
WO2023166351A1 (zh) * 2022-03-02 2023-09-07 杭州百诚医药科技股份有限公司 组胺h3受体抑制剂及其医药用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1636189A1 (en) * 2003-06-12 2006-03-22 Novo Nordisk A/S 1-aryl-4-(aryloxycarbonyl)-piperazine derivatives for use as inhibitors of hormone sensitive lipase
US8008301B2 (en) 2004-04-01 2011-08-30 Eli Lilly And Company Histamine H3 receptor agents, preparation and therapeutic uses
BRPI0511778A (pt) * 2004-06-02 2008-01-15 Hoffmann La Roche derivados da naftalina úteis como ligantes do receptor 3 da histamina
JP4652404B2 (ja) * 2004-06-21 2011-03-16 エフ.ホフマン−ラ ロシュ アーゲー ヒスタミン受容体アンタゴニストとしてのインドール誘導体
JP4942654B2 (ja) 2004-08-23 2012-05-30 イーライ リリー アンド カンパニー ヒスタミンh3受容体薬剤、製剤及び治療的使用
DE602006021626D1 (de) * 2005-11-30 2011-06-09 Hoffmann La Roche 1,1-dioxo-thiomorpholinyl-indolyl-methanon-derivate zur verwendung als h3-modulatoren
KR20090015098A (ko) 2006-05-30 2009-02-11 에프. 호프만-라 로슈 아게 피페리디닐 피리미딘 유도체
AU2008280257A1 (en) * 2007-07-25 2009-01-29 F. Hoffmann-La Roche Ag Benzofuran- and benzo[B]thiophene-2-carboxylic acid amide derivatives and use thereof as histamine 3 receptor modulators
US20090170869A1 (en) 2007-09-06 2009-07-02 Desmond John Best Piperazine derivative having affinity for the histamine h3 receptor
US7799816B2 (en) 2008-02-04 2010-09-21 Roche Palo Alto Llc Imidazolinylmethyl aryl sulfonamide
CN102046624A (zh) 2008-03-31 2011-05-04 埃沃特克股份有限公司 作为组胺h3受体拮抗剂的四氢萘啶及其氮杂衍生物
US8691804B2 (en) 2008-05-08 2014-04-08 Evotec Ag Azetidines and cyclobutanes as histamine H3 receptor antagonists
MX354852B (es) * 2010-09-02 2018-03-22 Suven Life Sciences Ltd Star Compuestos de heterociclilo comoligandos del receptor h3 de la histamina.

Also Published As

Publication number Publication date
JP5981654B2 (ja) 2016-08-31
BR112015001524A2 (pt) 2017-07-04
CN104540812A (zh) 2015-04-22
ES2592819T3 (es) 2016-12-01
CY1118035T1 (el) 2017-05-17
AU2012388383A1 (en) 2015-01-22
KR101707343B1 (ko) 2017-02-15
MX360001B (es) 2018-10-18
SG11201408423XA (en) 2015-01-29
HRP20161167T1 (hr) 2016-11-04
MX2015000064A (es) 2015-04-08
CA2878217C (en) 2016-05-17
AU2012388383B2 (en) 2015-12-10
HUE030901T2 (en) 2017-06-28
IL236437A0 (en) 2015-02-26
HK1204620A1 (en) 2015-11-27
AU2012388383C1 (en) 2016-03-17
US20150218129A1 (en) 2015-08-06
KR20150024918A (ko) 2015-03-09
EP2888243A1 (en) 2015-07-01
NZ703323A (en) 2016-03-31
BR112015001524B1 (pt) 2022-04-05
EA201590413A1 (ru) 2015-06-30
SMT201600336B (it) 2016-11-10
SI2888243T1 (sl) 2016-11-30
EA025136B1 (ru) 2016-11-30
DK2888243T3 (en) 2016-09-26
CN104540812B (zh) 2016-08-24
US9328092B2 (en) 2016-05-03
ME02519B (me) 2017-02-20
WO2014030170A1 (en) 2014-02-27
AP2014008139A0 (en) 2014-12-31
CA2878217A1 (en) 2014-02-27
LT2888243T (lt) 2016-10-10
PL2888243T3 (pl) 2017-01-31
PT2888243T (pt) 2016-09-21
JP2015526462A (ja) 2015-09-10
EP2888243B1 (en) 2016-08-17
IL236437A (en) 2016-12-29

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