RS51308B - Konjugati jedinjenja specifičnog makrolida imunske ćelije sa anti-inflamatornim jedinjenjima za poboljšano ćelijsko ciljanje u anti-inflamatornoj terapiji - Google Patents

Konjugati jedinjenja specifičnog makrolida imunske ćelije sa anti-inflamatornim jedinjenjima za poboljšano ćelijsko ciljanje u anti-inflamatornoj terapiji

Info

Publication number
RS51308B
RS51308B YUP-552/03A YUP55203A RS51308B RS 51308 B RS51308 B RS 51308B YU P55203 A YUP55203 A YU P55203A RS 51308 B RS51308 B RS 51308B
Authority
RS
Serbia
Prior art keywords
group
hydrogen
represented
carbon atoms
alkyl
Prior art date
Application number
YUP-552/03A
Other languages
English (en)
Inventor
Mladen Merčep
Milan MESIĆ
Linda Tomašković
Marijana Komac
Boska HRVAČIĆ
Stribor Marković
Original Assignee
Glaxosmithkline Istraživački Centar Zagreb D.O.O. Za Istraživanje I Razvoj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Istraživački Centar Zagreb D.O.O. Za Istraživanje I Razvoj filed Critical Glaxosmithkline Istraživački Centar Zagreb D.O.O. Za Istraživanje I Razvoj
Publication of YU55203A publication Critical patent/YU55203A/sh
Publication of RS51308B publication Critical patent/RS51308B/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
YUP-552/03A 2001-01-09 2002-01-03 Konjugati jedinjenja specifičnog makrolida imunske ćelije sa anti-inflamatornim jedinjenjima za poboljšano ćelijsko ciljanje u anti-inflamatornoj terapiji RS51308B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR20010018A HRP20010018A2 (en) 2001-01-09 2001-01-09 Novel anti-inflammatory compounds

Publications (2)

Publication Number Publication Date
YU55203A YU55203A (sh) 2006-03-03
RS51308B true RS51308B (sr) 2010-12-31

Family

ID=10947235

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-552/03A RS51308B (sr) 2001-01-09 2002-01-03 Konjugati jedinjenja specifičnog makrolida imunske ćelije sa anti-inflamatornim jedinjenjima za poboljšano ćelijsko ciljanje u anti-inflamatornoj terapiji

Country Status (24)

Country Link
US (2) US7446097B2 (sr)
EP (1) EP1351973B1 (sr)
JP (1) JP4474101B2 (sr)
CN (1) CN1269836C (sr)
AR (1) AR035727A1 (sr)
AT (1) ATE462713T1 (sr)
BG (1) BG108073A (sr)
BR (1) BR0206347A (sr)
CA (1) CA2434009C (sr)
CZ (1) CZ20031825A3 (sr)
DE (1) DE60235794D1 (sr)
EA (1) EA007061B1 (sr)
EE (1) EE05333B1 (sr)
ES (1) ES2342364T3 (sr)
GE (1) GEP20053607B (sr)
HK (1) HK1065320A1 (sr)
HR (1) HRP20010018A2 (sr)
HU (1) HUP0500180A3 (sr)
IL (1) IL156673A0 (sr)
PL (1) PL207636B1 (sr)
RS (1) RS51308B (sr)
SK (1) SK9792003A3 (sr)
UA (1) UA77166C2 (sr)
WO (1) WO2002055531A1 (sr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002109169A (ja) * 2000-09-29 2002-04-12 Hitachi Ltd 作業支援方法並びにシステム及び作業支援方法を記録した記録媒体
WO2003070174A2 (en) 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
EP1482957A4 (en) 2002-02-15 2006-07-19 Merckle Gmbh ANTIBIOTIC CONJUGATES
WO2003070173A2 (en) 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
RS20050006A (en) * 2002-07-08 2007-09-21 Glaxo Smith Kline Istraživački Centar Zagreb D.O.O., Novel compounds,compositions as carriers for steroid/non- steroid anti-inflammatory,antineoplastic and antiviral active molecules
JP2005536488A (ja) * 2002-07-08 2005-12-02 プリヴァ−イストラジヴァキ・インスティトゥ・ディー・オー・オー 新規な非ステロイド抗炎症物質、組成物、およびその使用方法
RU2330858C2 (ru) * 2002-07-08 2008-08-10 Глаксомитклайн Истраживацки Центар Загреб Д.О.О. Новые соединения, составы и способы лечения воспалительных заболеваний и состояний
HRP20030324A2 (en) * 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
JP4737495B2 (ja) * 2004-01-14 2011-08-03 塩野義製薬株式会社 エリスロマイシン誘導体
JP2008509899A (ja) * 2004-08-12 2008-04-03 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 胃腸管の炎症性疾患治療用の細胞特異的コンジュゲートの使用
US20060183696A1 (en) * 2004-08-12 2006-08-17 Pliva-Istrazivacki Institut D.O.O. Use of immune cell specific conjugates for treatment of inflammatory diseases of gastrointestinal tract
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
MX2007005073A (es) 2004-10-27 2007-06-25 Glaxosmithkline Zagreb Conjugados con actividad antiinflamtoria.
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
US20130045939A1 (en) * 2010-03-19 2013-02-21 Catabasis Pharmaceuticals, Inc. Fatty acid macrolide derivatives and their uses
US20150376225A1 (en) * 2013-01-23 2015-12-31 Sphaera Pharma Pvtd. Ltd. Novel compounds of 11beta-hydroxy-steroids for use in mitochondria biogenesis and diseases associated with mitochondrial dysfunction or depletion
WO2016013030A2 (en) 2014-07-23 2016-01-28 Sphaera Pharma Pvt. Ltd. Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
GB201520419D0 (en) 2015-11-19 2016-01-06 Epi Endo Pharmaceuticals Ehf Compounds
WO2023248010A2 (en) * 2022-06-23 2023-12-28 Synovo Gmbh Targeted modulators of jak3 for treatment of inflammatory and autoimmune diseases

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710495A (en) * 1980-07-10 1987-12-01 Otsuka Pharmaceutical Co., Ltd. Soft steroids having anti-inflammatory activity
HU198913B (en) 1987-09-03 1989-12-28 Pliva Pharm & Chem Works Process for producing 10-dihydro-10-deoxo-11-aza-erythronolide a-derivatives and pharmaceutical compositions containing them as active components
JPH01163124A (ja) * 1987-12-21 1989-06-27 Yamayuu Seikatsushiya:Kk 外用鎮痛消炎消腫消膿剤
SE9100341D0 (sv) 1991-02-04 1991-02-04 Astra Ab Novel steroids
SE9100342D0 (sv) 1991-02-04 1991-02-04 Astra Ab Novel steroid esters
GB9225923D0 (en) 1992-12-11 1993-02-03 Rhone Poulenc Rorer Ltd New compositions of matter
AU672669B2 (en) 1992-12-24 1996-10-10 Rhone-Poulenc Rorer Limited New steroids
EP0775489A4 (en) 1994-08-12 1998-05-06 Taisho Pharmaceutical Co Ltd INTERLEUKIN-5 PRODUCTION INHIBITOR
KR970704455A (ko) 1994-08-12 1997-09-06 우에하라 아끼라 인터류킨 5 생성 억제제(Interleukin 5 Production Inhibitor)
DE19542949A1 (de) 1995-11-17 1997-07-17 Hilti Ag Bolzen zum Eintreiben in harte Aufnahmewerkstoffe
US5928868A (en) * 1996-04-26 1999-07-27 Massachusetts Institute Of Technology Three hybrid screening assay
FR2776927B1 (fr) * 1998-04-07 2002-07-05 Univ Paris Curie Compositions pour la vectorisation de molecules
AU4549999A (en) * 1998-06-08 1999-12-30 Advanced Medicine, Inc. Novel polyene macrolide compounds and uses
CA2319495A1 (en) * 1998-06-08 1999-12-16 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
IT1306205B1 (it) 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
WO2003070174A2 (en) 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof

Also Published As

Publication number Publication date
CZ20031825A3 (cs) 2003-11-12
EE05333B1 (et) 2010-08-16
US7928078B2 (en) 2011-04-19
JP4474101B2 (ja) 2010-06-02
US20040198677A1 (en) 2004-10-07
HUP0500180A2 (en) 2006-09-28
IL156673A0 (en) 2004-01-04
BG108073A (bg) 2005-05-31
BR0206347A (pt) 2004-02-10
UA77166C2 (en) 2006-11-15
CN1269836C (zh) 2006-08-16
SK9792003A3 (en) 2004-01-08
CA2434009A1 (en) 2002-07-18
PL363478A1 (en) 2004-11-15
JP2004518670A (ja) 2004-06-24
CN1491230A (zh) 2004-04-21
EA200300781A1 (ru) 2003-12-25
US20090105163A1 (en) 2009-04-23
WO2002055531A1 (en) 2002-07-18
HK1065320A1 (en) 2005-02-18
EA007061B1 (ru) 2006-06-30
DE60235794D1 (de) 2010-05-12
ATE462713T1 (de) 2010-04-15
ES2342364T3 (es) 2010-07-06
GEP20053607B (en) 2005-09-12
PL207636B1 (pl) 2011-01-31
HUP0500180A3 (en) 2009-12-28
YU55203A (sh) 2006-03-03
EP1351973B1 (en) 2010-03-31
US7446097B2 (en) 2008-11-04
EP1351973A1 (en) 2003-10-15
EE200300293A (et) 2003-10-15
AR035727A1 (es) 2004-07-07
CA2434009C (en) 2009-09-29
HRP20010018A2 (en) 2002-12-31

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