RO99843B1 - Solutie injectabila, de uz veterinar, pentru rehidratarea organismului - Google Patents
Solutie injectabila, de uz veterinar, pentru rehidratarea organismuluiInfo
- Publication number
- RO99843B1 RO99843B1 RO131824A RO13182488A RO99843B1 RO 99843 B1 RO99843 B1 RO 99843B1 RO 131824 A RO131824 A RO 131824A RO 13182488 A RO13182488 A RO 13182488A RO 99843 B1 RO99843 B1 RO 99843B1
- Authority
- RO
- Romania
- Prior art keywords
- dextran
- average
- weight
- molecular weight
- injectable solution
- Prior art date
Links
- 229940102223 injectable solution Drugs 0.000 title abstract 2
- 229920002307 Dextran Polymers 0.000 abstract 5
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 229920002521 macromolecule Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Inventia se refera la o solutie injectabila, de uz veterinar, pentru rehidratarea organismului. Solutia conform inventiei este constituita dintr-o substanta macromoleculara medie, de 100000 a carei distributie a greutatii macromoleculare nu este nevoie sa fie prea strânsa. Dextranul partsial depolimerizat, folosit ca materie prima, este obtinut dine xtractul vativ (greutate moleculara medie 10 milioane) obtinut conform metodelor cunoscute, prin cresterea în conditii de temperatura, controlata a unor microorganisme, în special, Leuconostae mesenteroides, într-un mediu nutritiv potrivit, continând 10...15% zahar. Dextranul nativ se depolimerizeaza partial, prin tratarea cu acizi minerali diluati, la forme polimerice cu greutate moleculara mai mica. Fractiile cu diferite greutati moleculare se separa prin precipitare, si un solvent miscibil cu spa ca, de exemplu metanol, etanol sau acetona. Dextranul folosit în inventie are greutatea medie de 100000 fiind caracterizat prin limitele de viscozitate intrinseca, cuprinse în domeniul 0,27...0,32 dl/g, la 20 degree C. Solutia apoasa, injectabila, de dextran, are concentratia de 6%, aceasta având caracteristici fizico-chimice asemanatoare cu plasma sanguina. Alaturi de dextran, compozitia mai poate avea si electroliti de baza de Ce-, Na+, K+, Ca2+, Mg2+. pH-ul compozitiilor inventiei este cuprins între limitele 5,0...7,0. Sterilizare se face în autoclave, în ambalaje finale, flacoane de sticla.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO131824A RO99843B1 (ro) | 1988-01-19 | 1988-01-19 | Solutie injectabila, de uz veterinar, pentru rehidratarea organismului |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO131824A RO99843B1 (ro) | 1988-01-19 | 1988-01-19 | Solutie injectabila, de uz veterinar, pentru rehidratarea organismului |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RO99843B1 true RO99843B1 (ro) | 1990-09-28 |
Family
ID=40907897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO131824A RO99843B1 (ro) | 1988-01-19 | 1988-01-19 | Solutie injectabila, de uz veterinar, pentru rehidratarea organismului |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO99843B1 (ro) |
-
1988
- 1988-01-19 RO RO131824A patent/RO99843B1/ro unknown
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