RO130418A8 - Producerea şi utilizarea ovotransferinei pc2 () - Google Patents

Producerea şi utilizarea ovotransferinei pc2 ()

Info

Publication number
RO130418A8
RO130418A8 ROA201500008A RO201500008A RO130418A8 RO 130418 A8 RO130418 A8 RO 130418A8 RO A201500008 A ROA201500008 A RO A201500008A RO 201500008 A RO201500008 A RO 201500008A RO 130418 A8 RO130418 A8 RO 130418A8
Authority
RO
Romania
Prior art keywords
ovotransferrin
inactivated
admixture
purified
utilization
Prior art date
Application number
ROA201500008A
Other languages
English (en)
Other versions
RO130418A0 (ro
Inventor
Ionel-Victor Pătraşcu
Viorica Chiurciu
Constantin Chiurciu
Mariana Oporanu
Georgiana Topilescu
Iuliana Mihai
Original Assignee
Romvac Company S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romvac Company S.A. filed Critical Romvac Company S.A.
Priority to ROA201500008A priority Critical patent/RO130418A8/ro
Publication of RO130418A0 publication Critical patent/RO130418A0/ro
Priority to PCT/RO2016/000001 priority patent/WO2016114678A1/en
Publication of RO130418A8 publication Critical patent/RO130418A8/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Invenţia se referă la o metodă de obţinere a ovotransferinei utilizată ca produs biologic cu proprietăţi imunogene. Metoda conform invenţiei constă în imunizarea unor găini outoare convenţionale, cu un amestec de proteine purificate, preparate din corpi bacterieni inactivaţi, virusuri inactivate sau ciuperci inactivate, în amestec cu un adjuvant, prin administrare intramusculară, şi un imunomodulator, prin administrare orală în amestec cu furajul, inocularea cu antigen având loc de trei ori la un interval de 14 zile, după care se recoltează ouăle, se separă albuşurile, care se diluează 1:1 cu apă deionizată, se ajustează pH la 4,5..5, se precipită succesiv cu sulfat de amoniu şi acid citric, din care rezultă ovotransferină care este supusă dializei faţă de o soluţie de NaCl 0,15 M, sau se purifică şi se concentrează prin filtrare.
ROA201500008A 2015-01-13 2015-01-13 Producerea şi utilizarea ovotransferinei pc2 () RO130418A8 (ro)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ROA201500008A RO130418A8 (ro) 2015-01-13 2015-01-13 Producerea şi utilizarea ovotransferinei pc2 ()
PCT/RO2016/000001 WO2016114678A1 (en) 2015-01-13 2016-01-08 Preparation and use of immunologically active ovotransferrins (otf-pc-2)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ROA201500008A RO130418A8 (ro) 2015-01-13 2015-01-13 Producerea şi utilizarea ovotransferinei pc2 ()

Publications (2)

Publication Number Publication Date
RO130418A0 RO130418A0 (ro) 2015-07-30
RO130418A8 true RO130418A8 (ro) 2017-06-30

Family

ID=53718350

Family Applications (1)

Application Number Title Priority Date Filing Date
ROA201500008A RO130418A8 (ro) 2015-01-13 2015-01-13 Producerea şi utilizarea ovotransferinei pc2 ()

Country Status (2)

Country Link
RO (1) RO130418A8 (ro)
WO (1) WO2016114678A1 (ro)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO132299A3 (ro) * 2017-06-06 2018-12-28 Fântână Raul Sorin Compoziţie şi metodă de preparare şi evaluare a unui imunogen complex numit i-spga, destinat producerii de proteine imunologic active ()
CN110819690A (zh) * 2019-10-24 2020-02-21 广东环凯生物科技有限公司 一种金黄色葡萄球菌免疫磁珠洗液

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO130063A8 (ro) * 2014-08-28 2017-06-30 Romvac Company S.A. Producerea şi utilizarea ovotransferinei moderne ()

Also Published As

Publication number Publication date
RO130418A0 (ro) 2015-07-30
WO2016114678A1 (en) 2016-07-21

Similar Documents

Publication Publication Date Title
EP3132675A3 (en) Method and system of cultivating ophiocordyceps sinensis
CN103007278B (zh) 一种抗牙龈卟啉单胞菌和具核梭杆菌复合特异性IgY抗体及其制备方法和牙膏
AR108527A1 (es) Variantes de quimosina con propiedades mejoradas de coagulación de leche
CN108003240B (zh) 一种海水养殖鱼多联抗独特型卵黄抗体疫苗及其制备方法
MX2014005754A (es) Bacterias de ácido láctico y su uso como suplementos dietéticos para aves de corral.
MX2016010794A (es) Proteina bioactiva, uso de esta y metodo para su produccion.
RO130418A8 (ro) Producerea şi utilizarea ovotransferinei pc2 ()
MX2018000069A (es) Proceso para producir yema de huevo con alto contenido de factor antisecretor 16.
CN104606675B (zh) 一种禽用多联特异性卵黄抗体及转移因子的制备方法
RU2016147263A (ru) Новый ген гликозилтрансферазы и его применение
RU2019137459A (ru) Вакцины на основе реовирусов птиц
RU2017103382A (ru) Модификация продуцирования белков в растениях
MA40034A (fr) Fabrication et utilisation d'ovotransferrine moderne (otf-m)
US10124057B2 (en) Method of quickly producing antibodies against avian influenza and maintain antibody titer of duck
JP6709395B2 (ja) 冷水病ワクチン及び冷水病の予防方法
DD300833A7 (de) Verfahren zur herstellung von inaktivierten influenza-vollvirusimpfstoffen
RO130213A8 (ro) Producerea şi folosirea oului hiperimun - pc2
JP2008169142A (ja) 食中毒菌に対する抗体の産生方法
KR101862332B1 (ko) 인플루엔자 전바이러스 백신 제조 방법
RO132299A3 (ro) Compoziţie şi metodă de preparare şi evaluare a unui imunogen complex numit i-spga, destinat producerii de proteine imunologic active ()
EA202091492A1 (ru) Способ идентификации и выделения биологически активных соединений из экстрактов морских водорослей
RO130852A8 (ro) Producerea şi utilizarea oului hiperimun personalizat () în tratamentul de urgenţă al pacienţilor infectaţi cu germeni patogeni
MX2018008656A (es) Metodo para modificar la gemacion lateral.
Nguyen et al. Immunological properties of the chicken egg yolk (IgY) antibodies against Vietnamese cobra Naja Naja venom
EA201991083A1 (ru) Обработанный белковый продукт