RO123291B1 - Ointment for treating rheumatism - Google Patents

Abstract

The invention relates to an ointment for treating rheumatism. According to the invention, the ointment comprises spruce fir resin, bees wax, olive oil and walnut tree and black bryony leaves.

Description

The present invention relates to an ointment for the treatment of rheumatism, for use in the pharmaceutical industry.

In order to treat rheumatic disorders, various ointments are known such as Lasonil, Revulsin and Phenylbutazone, products that are obtained with synthetic chemical ingredients.

The disadvantages of these ointments are due to the adverse effect that the synthetic components can give and their high cost. Another disadvantage is that over time the expected and expected effect is continuously reduced.

For the same purpose of relieving rheumatic pain, the Boicil forte ointment is known, in which the composition (Heleborius species) enters, besides other components.

The disadvantage of this ointment is the low penetration power of the skin.

Patent RO 85671 refers to a waxed ointment, which consists in the fact that, for the application in dermatology, for the bacteriostatic, bactericidal, analgesic, anti-inflammatory, reparative and antiallergic action, it consists of: 15 g of crude resin, 70 g of oil of the sunflower and 15 g of yellow wax, to which is added 10 ml of distilled water.

Formula AS Magazine, no. 795, the year 2007 presents the medicinal uses of the root of the butter of the earth (Tamus communis), where it is mentioned from the beginning that: "the butter of the earth is used only externally, internally producing digestive and nervous disorders quite serious, wide its uses, checked" by folk medicine:

- in rheumatism - the root given on the grinder is applied directly to the skin, then covered with a clean piece of cloth and left for 5-15 minutes. The treated joint will warm up, the pain will lessen, after a few applications the joint mobility will be improved. The treatment is repeated daily, until the exit from the crisis;

- in sciatica - the application is made from rheumatism or a compress with a tincture of the butter of the earth, a compress that is kept for 30 minutes, after which the painful area is covered with a warm wool material. The application is made twice a day, until the complete elimination of the back pain ”.

S. Mocanu, D. Răducanu, in “Medicinal plants, vegetables, fruits and cereals in therapeutics”, pages 250-251, Military Publishing House, 1989, Bucharest, describes the external use of walnut leaves (Juglans regia) used in the form of general baths that "help to cure different skin diseases such as: eczema, ulcers, ulcers, furunculosis. In the form of compresses they are used in eye diseases. The decoction of walnut leaves is good for the gargle, in stomatitis (mouth disease) ”.

The technical problem proposed to be solved by the present application is the treatment of rheumatic pain and rheumatoid arthritis.

The solution is that the following components are associated in an ointment composition: spruce resin, beeswax, olive oil, ground butter and walnut leaves, along with volcanic water.

The ointment for treating rheumatism, according to the invention, consists of: 25 parts spruce resin, 25 parts beeswax, 50 parts olive oil and active ingredients obtained from 30 parts Radix Tamus communis, 5 parts Folium Juglans regulate 1000 parts volcanic water , the parts being expressed by weight.

Following the application of the invention, the following advantages are obtained:

- increased anti-inflammatory and analgesic effects;

- shortening the action time;

- very good tolerance;

- relieving rheumatic pain and rheumatoid arthritis;

- increasing the therapeutic effect of the ointment through the synergy of the natural components contained and which can be easily absorbed.

RO 123291 Β1

The following is an example of making the ointment according to the invention. 1 Embodiment example. The aim was to obtain 100 g ointment for the treatment of rheumatism, which is prepared from 25 g spruce resin (Picea abies resin), 25 g 3 beeswax (Cere alba) and 50 g of olive oil (O / ea europaea oii ). These components are introduced into a stainless steel vessel, sterile and equipped with a stirrer, and heated by 5 Bain-Marie process, until the spruce resin and beeswax are melted. At the end of the melting operation, which takes place at about 60 ° C, the components are mixed for 7 hours

3 .. .4 min, for a good homogenization.

The hot mixture thus obtained is poured into 1000 g of volcanic water in which 9 decoctions of 30 g of ground butter (Ta mus communis) and 5 g of walnut leaves (FoliumJuglans regia) were obtained. The root of the ground butter, freshly harvested, was washed very well before use and shredded, and the walnut leaves were previously dried and shredded. 13

The root of the butter of the earth is known in folk medicine, only for external use, being used in the relief of rheumatic and sciatic pain. Used in this way, 15 if applied fresh, directly on the skin, it can give allergic skin reactions, also having a strong rubefic effect. 17

Walnut leaves, which contain, among others: tannin, a volatile oil and vitamin C, are well known for their external antiseptic, anti-inflammatory and anti-hematopoietic effect. These 19 are used in the composition of the ointment according to the invention, precisely because of the effect they have on the healing of different skin diseases, and here, explicitly, to counteract the possible 21 above-mentioned allergic effect of the root of the butter of the earth.

Beeswax, another ingredient of the ointment according to the invention, is used 23 because, in addition to stabilizing the composition, it gives consistency to the ointment and has bactericidal properties. In turn, the spruce resin is used for its beneficial action: anti-inflammatory, antirheumatic, healing and antiseptic.

as far as olive oil is concerned, it contains oleic acid, monounsaturated fatty acids and many vitamins; Its use in the above composition aims to obtain a good oilyness of the ointment, according to the invention and the protection of the skin. 29

To the components listed above, an antimicrobial preservative, such as nipasol, can optionally be added in a small amount, such as, for example, 31 0.2 ... 0.3 g.

Returning to the process of obtaining, raise the temperature of the vessel to 33 about 100 ° C and keep for 30 ... 35 minutes, the heating associated with a continuous and slight stirring of about 60 rpm, to homogenize the mixture . 35

Once this heating and homogenization of the ingredients is completed, the mixture is filtered to remove the vegetable mass, then allowed to cool until it reaches 37 at 25 ... 30 ° C and at the top of the vessel a solid crust that comes out in a stainless steel vessel and mixes for 4-5 minutes for homogenization.39

A solid, homogeneous, yellow-greenish-yellow, with a slight spruce-like odor and good stretching on the skin, ointment 41, is well absorbed through the massage. The ointment has a pH of 5.5, a viscosity of

230 .. .250 cPs and a drop point of about 55 ° C.43

The product is placed in tubes or boxes made of plastic, with protective films and threaded caps and stored in a dry place and at temperatures up to 20 ° C.45

RO 123291 Β1

CLINICAL TESTS

The ointment for the treatment of rheumatism, according to the invention, has been tested on a number of 38 persons, aged between 47 and 79 years, patients who are volunteers and willing to try the effects of the ointment, 12 of them being people assisted from a home of 5 elderly, and 11 patients in a geriatric hospital.

The treatment consisted of applying the ointment, according to the invention, three times a day, 7 on the painful or inflamed areas, in 3-4 thin layers, each followed by a light, local massage, in order to absorb the active substances. It is desirable that after applying the ointment 9 and the regular massage of the affected area, the massage should be completed by performing some circular movements of the palm, changing every three turns their meaning.

After 10 days of treatment, there was a real improvement in the condition of the patients, which declared a considerable reduction of the pain and increased mobility of the sick joints. The healing rate was almost 88%, the other 12% being made up of people with chronic illnesses, and of these, half were over 75 years old.

The ointment according to the invention has been tested both in terms of product safety and immediate irritant potential; Following these tests, it was found that the ointment for treating rheumatism, according to the invention, is non-irritating, and the composition complies with the national regulations in force.

Claims (1)

Ointment for the treatment of rheumatism, characterized in that it consists of 3 parts: 25 parts spruce resin, 25 parts beeswax, 50 parts olive oil and active ingredients obtained from 30 parts Radix Tamus communis, 5 parts Folium Juglans directed by 1000 5 parts volcanic water, parts being expressed by weight.