PT99929A - Processo para a preparacao de cadeias alfa recombinantes do receptor humano da interleucina 5 e de composicoes farmaceuticas que as contem - Google Patents

Processo para a preparacao de cadeias alfa recombinantes do receptor humano da interleucina 5 e de composicoes farmaceuticas que as contem Download PDF

Info

Publication number
PT99929A
PT99929A PT99929A PT9992991A PT99929A PT 99929 A PT99929 A PT 99929A PT 99929 A PT99929 A PT 99929A PT 9992991 A PT9992991 A PT 9992991A PT 99929 A PT99929 A PT 99929A
Authority
PT
Portugal
Prior art keywords
leu
ser
glu
lys
ala
Prior art date
Application number
PT99929A
Other languages
English (en)
Portuguese (pt)
Inventor
Walter Fiers
Jan Tavernier
Rene Devos
Geert Plaetinck
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT99929A publication Critical patent/PT99929A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT99929A 1990-12-27 1991-12-23 Processo para a preparacao de cadeias alfa recombinantes do receptor humano da interleucina 5 e de composicoes farmaceuticas que as contem PT99929A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90811030 1990-12-27
EP91810327 1991-04-30

Publications (1)

Publication Number Publication Date
PT99929A true PT99929A (pt) 1993-01-29

Family

ID=26127858

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99929A PT99929A (pt) 1990-12-27 1991-12-23 Processo para a preparacao de cadeias alfa recombinantes do receptor humano da interleucina 5 e de composicoes farmaceuticas que as contem

Country Status (16)

Country Link
EP (1) EP0492214A3 (enExample)
JP (1) JP2554418B2 (enExample)
KR (1) KR920012440A (enExample)
AR (1) AR246310A1 (enExample)
AU (1) AU647560B2 (enExample)
CA (1) CA2058003A1 (enExample)
FI (1) FI916067L (enExample)
HU (1) HUT59725A (enExample)
IE (1) IE914548A1 (enExample)
IL (1) IL100470A0 (enExample)
MX (1) MX9102767A (enExample)
NO (1) NO915084L (enExample)
NZ (1) NZ241094A (enExample)
PT (1) PT99929A (enExample)
TW (1) TW280833B (enExample)
YU (1) YU199691A (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5453491A (en) * 1990-09-11 1995-09-26 Kiyoshi Takatsu Murine interleukin-5 receptor
US5965362A (en) 1992-03-04 1999-10-12 The Regents Of The University Of California Comparative genomic hybridization (CGH)
US5677280A (en) * 1995-06-07 1997-10-14 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
US5668110A (en) * 1995-06-07 1997-09-16 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
US5654276A (en) * 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
US5683983A (en) * 1995-06-07 1997-11-04 Glaxo Group Limited Peptides and compounds that bind to the IL-5 receptor
ES2233974T3 (es) * 1995-09-11 2005-06-16 Kyowa Hakko Kogyo Co., Ltd. Anticuerpo contra la cadena alfa del receptor de la interleucina 5 humana.
US7049424B2 (en) 1996-07-15 2006-05-23 The Regents Of The University Of California Genes from the 20Q13 amplicon and their uses
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
WO1997026332A1 (en) * 1996-01-17 1997-07-24 Schering Corporation Baculovirus expression system for human interleukin 5 receptor and method of screening for interleukin 5 antagonists
US5861279A (en) * 1996-01-17 1999-01-19 Schering Corporation Baculovirus expression system for human interleukin 5 receptor and method of screening for interleukin 5 antagonists
FR2783326B1 (fr) * 1998-09-10 2000-12-01 Immunotech Sa Procede de detection ou de quantification des basophiles et des eosinophiles
US7109299B1 (en) 1999-12-16 2006-09-19 Affymax, Inc. Peptides and compounds that bind to the IL-5 receptor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5453491A (en) * 1990-09-11 1995-09-26 Kiyoshi Takatsu Murine interleukin-5 receptor

Also Published As

Publication number Publication date
IL100470A0 (en) 1992-09-06
JPH0678772A (ja) 1994-03-22
FI916067A7 (fi) 1992-06-28
EP0492214A3 (en) 1992-09-09
AR246310A1 (es) 1994-07-29
NO915084D0 (no) 1991-12-23
YU199691A (sh) 1994-06-24
MX9102767A (es) 1992-06-30
FI916067A0 (fi) 1991-12-20
FI916067L (fi) 1992-06-28
CA2058003A1 (en) 1992-06-28
EP0492214A2 (en) 1992-07-01
KR920012440A (ko) 1992-07-27
IE914548A1 (en) 1992-07-01
AU8998591A (en) 1992-10-15
AU647560B2 (en) 1994-03-24
HUT59725A (en) 1992-06-29
HU913961D0 (en) 1992-02-28
NZ241094A (en) 1993-07-27
TW280833B (enExample) 1996-07-11
NO915084L (no) 1992-06-29
JP2554418B2 (ja) 1996-11-13

Similar Documents

Publication Publication Date Title
US5455337A (en) DNA encoding chimeric polypeptides comprising the interleukin-5 receptor α-chain fused to immunoglobulin heavy chain constant regions
US5760204A (en) DNA encoding murine interleukin-5 receptor
EP0417563B1 (de) TNF-bindende Proteine
CA2263889C (en) P-selectin ligand proteins
CZ300818B6 (cs) Interleukin-18-vazebné proteiny, príprava a použití
BG64755B1 (bg) Модулатори на tnf рецептор асоцииран фактор (traf), тяхното получаване и употреба
AU705595B2 (en) Interleukin-1 type 3 receptors
JP2554418B2 (ja) ヒトインターロイキン−5受容体のα鎖又はその一部、特にshIL5RαをコードするDNA及びそれを含むベクター、このベクターで形質転換された宿主細胞、ならびにその製造及び利用方法
ES2134771T5 (es) Adn que codifica el receptor del factor estimulador de una colonia de granulocitos.
AU620466B2 (en) Interferon-gamma binding proteins
JP3921271B2 (ja) グルクロン酸転移酵素をコードするdna
WO1998038302A2 (en) TETRODOTOXIN-SENSITIVE SODIUM CHANNEL α-SUBUNIT
PL200763B1 (pl) Sekwencja DNA i kodowane przez nią białko RAP-2, izoforma, fragment, analog funkcjonalny i pochodna, oraz sposób ich wytwarzania, nośnik ekspresji i transformowana nim komórka gospodarza, przeciwciało i jego czynny fragment i pochodna, kompozycja farmaceutyczna oraz zastosowania
JPS611392A (ja) IgE結合因子活性を示すポリペプチドをコ−ドするcDNAクロ−ン
AU9327298A (en) Nucleic acid encoding a nervous tissue sodium channel
US6423829B1 (en) Nitrobenzylmercaptopurineriboside (NBMPR)-insensitive, equilibrative, nucleoside transport protein, nucleic acids encoding the same and methods of use
JPH10504714A (ja) ヒトカリウムチャンネル1および2タンパク質
DE69836226T2 (de) Ifn rezeptor 1 bindende proteine, dafür kodierende dna und verfahren zur regulierung der zellulären antwort auf interferone
US6239268B1 (en) Interleukin-1 type 3 receptors
WO1998046749A9 (en) A nitrobenzylmercaptopurineriboside (nbmpr)-insensitive, equilibrative, nucleoside transport protein, nucleic acids encoding the same and methods of use
WO1998046749A1 (en) A nitrobenzylmercaptopurineriboside (nbmpr)-insensitive, equilibrative, nucleoside transport protein, nucleic acids encoding the same and methods of use
EP0759940A1 (en) A dna molecule encoding a mast cell function-associated antigen (mafa)
US20070054310A1 (en) Novel polypeptide, cDNA encoding the same, and use thereof
WO2001038545A1 (en) A novel polypeptide, a human acetyl galactosyl transferase 45 and the polynucleotide encoding the polypeptide
WO2001000664A2 (en) Secreted alpha-helical protein-36

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920827

FC3A Refusal

Effective date: 19990304