PT99777A - Processo para a preparacao de compostos bifenililo - Google Patents

Processo para a preparacao de compostos bifenililo

Info

Publication number
PT99777A
PT99777A PT99777A PT9977791A PT99777A PT 99777 A PT99777 A PT 99777A PT 99777 A PT99777 A PT 99777A PT 9977791 A PT9977791 A PT 9977791A PT 99777 A PT99777 A PT 99777A
Authority
PT
Portugal
Prior art keywords
preparation
biphenylyl
compounds
biphenylyl compounds
Prior art date
Application number
PT99777A
Other languages
English (en)
Other versions
PT99777B (pt
Inventor
Peter Buhlmayer
Franz Ostermayer
Tibur Schmidlin
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT99777A publication Critical patent/PT99777A/pt
Publication of PT99777B publication Critical patent/PT99777B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
PT99777A 1990-12-14 1991-12-12 Processo para a preparacao de compostos bifenililo PT99777B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH396590 1990-12-14

Publications (2)

Publication Number Publication Date
PT99777A true PT99777A (pt) 1992-12-31
PT99777B PT99777B (pt) 1999-05-31

Family

ID=4267265

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99777A PT99777B (pt) 1990-12-14 1991-12-12 Processo para a preparacao de compostos bifenililo

Country Status (14)

Country Link
US (1) US5369110A (pt)
EP (1) EP0490820A3 (pt)
JP (1) JPH04300859A (pt)
KR (1) KR920012051A (pt)
AU (1) AU657498B2 (pt)
CA (1) CA2057511A1 (pt)
FI (1) FI915841A (pt)
HU (1) HUT59660A (pt)
IE (1) IE914358A1 (pt)
IL (1) IL100267A0 (pt)
MX (1) MX9102500A (pt)
NO (1) NO914926L (pt)
PT (1) PT99777B (pt)
ZA (1) ZA919837B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0528762B1 (de) * 1991-08-15 1997-05-07 Novartis AG N-Acyl-N-Heterocyclyl- oder Naphthylalkyl-Aminosäuren als Angiotensin II Antagonisten
US5312820A (en) * 1992-07-17 1994-05-17 Merck & Co., Inc. Substituted carbamoyl and oxycarbonyl derivatives of biphenylmethylamines
US6307090B1 (en) 1999-01-22 2001-10-23 The United States Of America As Represented By The Department Of Health And Human Services Acylated oligopeptide derivatives having cell signal inhibiting activity
JP4604161B2 (ja) * 1999-03-23 2010-12-22 アメリカ合衆国 フェニルアラニン誘導体
US7226991B1 (en) * 1999-03-23 2007-06-05 United States Of America, Represented By The Secretary, Department Of Health And Human Services Phenylalanine derivatives
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
US7871981B2 (en) * 1999-10-22 2011-01-18 The United States Of America As Represented By The Department Of Health And Human Services Inhibition of cell motility, angiogenesis, and metastasis
DE60034959T2 (de) 1999-10-22 2008-01-17 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Hemmung der zellmotilität und angiogenese mit grb2 sh2-domäne inhibitoren
EP1383792A2 (en) * 2000-08-22 2004-01-28 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Sh2 domain binding inhibitors
US7425537B2 (en) * 2000-08-22 2008-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services SH2 domain binding inhibitors
US20040138104A1 (en) * 2003-01-14 2004-07-15 The Government Of The United States Of America Represented By The Secretary, Peptides
US20050119163A1 (en) * 2003-09-18 2005-06-02 The Government Of The United States Of America, As Represented By The Secretary, SH2 domain binding inhibitors
DE102004060542A1 (de) 2004-12-16 2006-07-06 Sanofi-Aventis Deutschland Gmbh Hydroxybiphenyl-Carbonsäuren und Derivate, Verfahren zu deren Herstellung und deren Verwendung
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3239170B1 (en) 2008-06-04 2019-03-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839B1 (en) 2008-07-16 2019-09-04 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2013022243A2 (ko) * 2011-08-05 2013-02-14 동국대학교 산학협력단 신규한 바이페닐 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 염증성 질환 또는 자가면역질환의 예방 또는 치료용 약학적 조성물
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法
GB202014589D0 (en) * 2020-09-16 2020-10-28 Ucl Business Ltd Agents for use in the treatment of amyloidosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
IL95975A (en) * 1989-10-24 1997-06-10 Takeda Chemical Industries Ltd N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
IL96019A0 (en) * 1989-10-31 1991-07-18 Fujisawa Pharmaceutical Co Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
PH30484A (en) * 1990-02-19 1997-05-28 Ciba Geigy Acy compounds pharmaceutical composition containing said compound and method of use thereof
FR2677016A1 (fr) * 1991-05-31 1992-12-04 Union Pharma Scient Appl Nouveaux derives d'amide antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
IE914358A1 (en) 1992-06-17
PT99777B (pt) 1999-05-31
EP0490820A2 (de) 1992-06-17
MX9102500A (es) 1992-06-01
FI915841A (fi) 1992-06-15
CA2057511A1 (en) 1992-06-15
FI915841A0 (fi) 1991-12-11
HUT59660A (en) 1992-06-29
HU913952D0 (en) 1992-02-28
NO914926L (no) 1992-06-15
JPH04300859A (ja) 1992-10-23
NO914926D0 (no) 1991-12-13
IL100267A0 (en) 1992-09-06
EP0490820A3 (en) 1992-10-28
US5369110A (en) 1994-11-29
ZA919837B (en) 1992-09-30
KR920012051A (ko) 1992-07-25
AU8831891A (en) 1992-06-18
AU657498B2 (en) 1995-03-16

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920818

FG3A Patent granted, date of granting

Effective date: 19990222

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000831