PT990655E - Metodo de secagem de cloridrato de paroxetina anidro - Google Patents
Metodo de secagem de cloridrato de paroxetina anidroInfo
- Publication number
- PT990655E PT990655E PT99945685T PT99945685T PT990655E PT 990655 E PT990655 E PT 990655E PT 99945685 T PT99945685 T PT 99945685T PT 99945685 T PT99945685 T PT 99945685T PT 990655 E PT990655 E PT 990655E
- Authority
- PT
- Portugal
- Prior art keywords
- isopropyl alcohol
- hydrochloride anhydrate
- paroxetine hydrochloride
- drying
- paroxetine
- Prior art date
Links
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title abstract 12
- 238000001035 drying Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 229960002296 paroxetine Drugs 0.000 title abstract 2
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 title 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 15
- 229960005183 paroxetine hydrochloride Drugs 0.000 abstract 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- -1 paroxetine compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10105898A JP3796351B2 (ja) | 1998-04-13 | 1998-04-13 | パロキセチン塩酸塩無水和物の乾燥方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT990655E true PT990655E (pt) | 2003-11-28 |
Family
ID=14290525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99945685T PT990655E (pt) | 1998-04-13 | 1999-04-12 | Metodo de secagem de cloridrato de paroxetina anidro |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6541637B1 (https=) |
| EP (1) | EP0990655B1 (https=) |
| JP (1) | JP3796351B2 (https=) |
| AT (1) | ATE244237T1 (https=) |
| AU (1) | AU730652B2 (https=) |
| CA (1) | CA2294716C (https=) |
| DE (1) | DE69909207T2 (https=) |
| ES (1) | ES2199592T3 (https=) |
| PT (1) | PT990655E (https=) |
| WO (1) | WO1999052902A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1394160A1 (en) | 1996-06-13 | 2004-03-03 | SUMIKA FINE CHEMICALS Co., Ltd. | Process for preparing crystalline paroxetin hydrochloride |
| CA2339857A1 (en) * | 1998-08-07 | 2000-02-17 | Neal Ward | Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride |
| GB9826176D0 (en) * | 1998-11-28 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| US9138430B2 (en) * | 2007-12-27 | 2015-09-22 | Mylan Specialty L.P. | Formulation and method for the release of paroxetine in the large intestine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR001982A1 (es) * | 1995-02-06 | 1998-01-07 | Smithkline Beecham Plc | Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion |
| US5856493A (en) * | 1995-02-06 | 1999-01-05 | Smithkline Beecham Corporation | Process for making novel form of paroxeting hydrochloride anhydrate |
| EP1394160A1 (en) * | 1996-06-13 | 2004-03-03 | SUMIKA FINE CHEMICALS Co., Ltd. | Process for preparing crystalline paroxetin hydrochloride |
| JP3819532B2 (ja) | 1996-06-13 | 2006-09-13 | 住友化学株式会社 | ピペリジン誘導体およびその製造方法 |
| CA2339857A1 (en) | 1998-08-07 | 2000-02-17 | Neal Ward | Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride |
-
1998
- 1998-04-13 JP JP10105898A patent/JP3796351B2/ja not_active Expired - Fee Related
-
1999
- 1999-04-12 EP EP99945685A patent/EP0990655B1/en not_active Expired - Lifetime
- 1999-04-12 ES ES99945685T patent/ES2199592T3/es not_active Expired - Lifetime
- 1999-04-12 CA CA002294716A patent/CA2294716C/en not_active Expired - Fee Related
- 1999-04-12 AT AT99945685T patent/ATE244237T1/de active
- 1999-04-12 PT PT99945685T patent/PT990655E/pt unknown
- 1999-04-12 US US09/445,598 patent/US6541637B1/en not_active Expired - Fee Related
- 1999-04-12 AU AU52656/99A patent/AU730652B2/en not_active Ceased
- 1999-04-12 DE DE69909207T patent/DE69909207T2/de not_active Expired - Lifetime
- 1999-04-12 WO PCT/JP1999/001914 patent/WO1999052902A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69909207D1 (de) | 2003-08-07 |
| DE69909207T2 (de) | 2004-04-22 |
| WO1999052902A1 (en) | 1999-10-21 |
| EP0990655B1 (en) | 2003-07-02 |
| EP0990655A1 (en) | 2000-04-05 |
| EP0990655A4 (en) | 2001-10-04 |
| ES2199592T3 (es) | 2004-02-16 |
| US6541637B1 (en) | 2003-04-01 |
| CA2294716A1 (en) | 1999-10-21 |
| CA2294716C (en) | 2004-08-03 |
| JP3796351B2 (ja) | 2006-07-12 |
| AU730652B2 (en) | 2001-03-08 |
| JP2001072677A (ja) | 2001-03-21 |
| AU5265699A (en) | 1999-11-01 |
| ATE244237T1 (de) | 2003-07-15 |
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