PT98539A - Processo de preparacao de oxidos de difenil-(1,8-dissubstituido-octa-2,3,5-tri-en-7-ino)fosfeno de composicoes farmaceuticas e de clivagem de adn - Google Patents

Processo de preparacao de oxidos de difenil-(1,8-dissubstituido-octa-2,3,5-tri-en-7-ino)fosfeno de composicoes farmaceuticas e de clivagem de adn

Info

Publication number
PT98539A
PT98539A PT98539A PT9853991A PT98539A PT 98539 A PT98539 A PT 98539A PT 98539 A PT98539 A PT 98539A PT 9853991 A PT9853991 A PT 9853991A PT 98539 A PT98539 A PT 98539A
Authority
PT
Portugal
Prior art keywords
dissubstituide
cliving
difenyl
octa
ino
Prior art date
Application number
PT98539A
Other languages
English (en)
Other versions
PT98539B (pt
Inventor
Kyriacos C Nicolaou
Peter E Maligres
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of PT98539A publication Critical patent/PT98539A/pt
Publication of PT98539B publication Critical patent/PT98539B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
    • C07F9/5316—Unsaturated acyclic phosphine oxides or thioxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT98539A 1990-08-01 1991-08-01 Processo de preparacao de oxidos de difenil-(1,8-dissubstituido-octa-2,3,5-tri-en-7-ino)fosfeno de composicoes farmaceuticas e de clivagem de adn PT98539B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/561,455 US5229375A (en) 1990-08-01 1990-08-01 Phosphene oxide-terminated allene-ene-yne dna-cleaving, antitumor and antibiotic molecules

Publications (2)

Publication Number Publication Date
PT98539A true PT98539A (pt) 1992-06-30
PT98539B PT98539B (pt) 1999-01-29

Family

ID=24242045

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98539A PT98539B (pt) 1990-08-01 1991-08-01 Processo de preparacao de oxidos de difenil-(1,8-dissubstituido-octa-2,3,5-tri-en-7-ino)fosfeno de composicoes farmaceuticas e de clivagem de adn

Country Status (9)

Country Link
US (1) US5229375A (pt)
EP (1) EP0541670A4 (pt)
JP (1) JPH05509102A (pt)
AU (1) AU639132B2 (pt)
CA (1) CA2085599A1 (pt)
FI (1) FI930378A (pt)
IE (1) IE912711A1 (pt)
PT (1) PT98539B (pt)
WO (1) WO1992002227A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604384A (en) * 1993-02-08 1997-02-18 Winner International Royalty Corporation Anti-theft device for motor vehicle
US5770736A (en) * 1994-06-21 1998-06-23 Northeastern University Reagents for cleavage or crosslinking of biomolecules using nondiffusible reactive intermediates
CN105348321B (zh) * 2015-11-11 2017-10-10 南京师范大学 一种合成α，α‑二氟亚甲基烯基膦酸酯的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1509866A (en) * 1975-06-10 1978-05-04 Johnson & Johnson Enteric coated digestive enzyme compositions

Also Published As

Publication number Publication date
JPH05509102A (ja) 1993-12-16
FI930378A0 (fi) 1993-01-29
IE912711A1 (en) 1992-02-12
US5229375A (en) 1993-07-20
CA2085599A1 (en) 1992-02-02
FI930378A (fi) 1993-01-29
PT98539B (pt) 1999-01-29
EP0541670A4 (en) 1993-06-16
WO1992002227A1 (en) 1992-02-20
AU8316691A (en) 1992-03-02
AU639132B2 (en) 1993-07-15
EP0541670A1 (en) 1993-05-19

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Legal Events

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BB1A Laying open of patent application

Effective date: 19920207

FG3A Patent granted, date of granting

Effective date: 19981013

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000430