PT96795A - Processo para a preparacao de analogos de peptidos - Google Patents

Processo para a preparacao de analogos de peptidos

Info

Publication number
PT96795A
PT96795A PT96795A PT9679591A PT96795A PT 96795 A PT96795 A PT 96795A PT 96795 A PT96795 A PT 96795A PT 9679591 A PT9679591 A PT 9679591A PT 96795 A PT96795 A PT 96795A
Authority
PT
Portugal
Prior art keywords
cmh2m
alkyl
nr8r9
conr8r9
pyranyloxy
Prior art date
Application number
PT96795A
Other languages
English (en)
Other versions
PT96795B (pt
Inventor
Horst Juraszyk
Peter Raddatz
Johannes Sombroek
Claus J Schmitges
Klaus-Otto Minck
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PT96795A publication Critical patent/PT96795A/pt
Publication of PT96795B publication Critical patent/PT96795B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT96795A 1990-02-16 1991-02-15 Processo para a preparacao de analogos de peptidos PT96795B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4004898A DE4004898A1 (de) 1990-02-16 1990-02-16 Peptid-analoga

Publications (2)

Publication Number Publication Date
PT96795A true PT96795A (pt) 1991-10-31
PT96795B PT96795B (pt) 1998-07-31

Family

ID=6400333

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96795A PT96795B (pt) 1990-02-16 1991-02-15 Processo para a preparacao de analogos de peptidos

Country Status (16)

Country Link
US (1) US5401722A (pt)
EP (1) EP0446485B1 (pt)
JP (1) JPH06220086A (pt)
KR (1) KR910015593A (pt)
AT (1) ATE127473T1 (pt)
AU (1) AU638099B2 (pt)
CA (1) CA2036345A1 (pt)
DE (2) DE4004898A1 (pt)
DK (1) DK0446485T3 (pt)
ES (1) ES2076288T3 (pt)
GR (1) GR3017572T3 (pt)
HU (1) HUT59159A (pt)
IE (1) IE68676B1 (pt)
PT (1) PT96795B (pt)
TW (1) TW198682B (pt)
ZA (1) ZA911156B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4215874A1 (de) * 1992-05-14 1993-11-18 Bayer Ag Dithiolanylglycinhaltige HIV-Proteaseinhibitoren vom Hydroxyethylenisostertyp
US5760019A (en) * 1996-07-12 1998-06-02 The Research Foundation Of State University Of New York Silanol enzyme inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8605573D0 (sv) * 1986-12-29 1986-12-29 Haessle Ab Novel compounds
US4820691A (en) * 1987-06-24 1989-04-11 E. R. Squibb & Sons, Inc. Amino acid 1,2-diketo derivatives as renin inhibitors

Also Published As

Publication number Publication date
DE59009634D1 (de) 1995-10-12
EP0446485B1 (de) 1995-09-06
ATE127473T1 (de) 1995-09-15
ES2076288T3 (es) 1995-11-01
AU7115091A (en) 1991-08-22
JPH06220086A (ja) 1994-08-09
GR3017572T3 (en) 1995-12-31
DE4004898A1 (de) 1991-08-22
AU638099B2 (en) 1993-06-17
TW198682B (pt) 1993-01-21
IE68676B1 (en) 1996-07-10
ZA911156B (en) 1991-11-27
HUT59159A (en) 1992-04-28
KR910015593A (ko) 1991-09-30
HU910508D0 (en) 1991-09-30
DK0446485T3 (da) 1995-10-23
PT96795B (pt) 1998-07-31
EP0446485A3 (en) 1992-07-22
US5401722A (en) 1995-03-28
IE910534A1 (en) 1991-08-28
CA2036345A1 (en) 1991-08-17
EP0446485A2 (de) 1991-09-18

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910702

FG3A Patent granted, date of granting

Effective date: 19980407

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991031