PT96723A - Metodo para a destoxificacao de um antigenio toxico - Google Patents
Metodo para a destoxificacao de um antigenio toxicoInfo
- Publication number
- PT96723A PT96723A PT96723A PT9672391A PT96723A PT 96723 A PT96723 A PT 96723A PT 96723 A PT96723 A PT 96723A PT 9672391 A PT9672391 A PT 9672391A PT 96723 A PT96723 A PT 96723A
- Authority
- PT
- Portugal
- Prior art keywords
- detoxification
- toxic antigen
- detoxified
- pertussis toxin
- antigen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47909890A | 1990-02-12 | 1990-02-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT96723A true PT96723A (pt) | 1991-10-31 |
PT96723B PT96723B (pt) | 1998-07-31 |
Family
ID=23902647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96723A PT96723B (pt) | 1990-02-12 | 1991-02-08 | Metodo para a destoxificacao de um antigenio toxico |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0515415B1 (pt) |
JP (1) | JP3035712B2 (pt) |
KR (1) | KR100202052B1 (pt) |
AT (1) | ATE129159T1 (pt) |
AU (1) | AU646019B2 (pt) |
CA (1) | CA2075711C (pt) |
CY (1) | CY1935A (pt) |
DE (1) | DE69113991T2 (pt) |
DK (1) | DK0515415T3 (pt) |
ES (1) | ES2080941T3 (pt) |
GR (1) | GR3018440T3 (pt) |
HK (1) | HK1004524A1 (pt) |
IE (1) | IE70672B1 (pt) |
NZ (1) | NZ237069A (pt) |
PT (1) | PT96723B (pt) |
WO (1) | WO1991012020A1 (pt) |
ZA (1) | ZA91947B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT835663E (pt) | 1992-05-23 | 2010-01-04 | Glaxosmithkline Biolog Sa | Vacinas combinadas compreendendo o antigénio de superfície da hepatite b e outros antigénios |
GB9216351D0 (en) * | 1992-07-31 | 1992-09-16 | Wellcome Found | Vaccine production |
JP4601823B2 (ja) * | 1998-09-01 | 2010-12-22 | メリオン リサーチ スリー リミテッド | 経口ワクチン組成物 |
AU769539B2 (en) * | 1999-01-29 | 2004-01-29 | Zoetis Services Llc | Adjuvants for use in vaccines |
GB0313916D0 (en) | 2003-06-16 | 2003-07-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
US9475848B2 (en) | 2012-02-01 | 2016-10-25 | Glaxosmithkline Biologicals S.A. | Fermentation process for producing a virulence factor from bordetella |
US20140037680A1 (en) | 2012-08-06 | 2014-02-06 | Glaxosmithkline Biologicals, S.A. | Novel method |
AU2013301312A1 (en) | 2012-08-06 | 2015-03-19 | Glaxosmithkline Biologicals S.A. | Method for eliciting in infants an immune response against RSV and B. pertussis |
US8916173B2 (en) | 2013-03-08 | 2014-12-23 | Crucell Holland B.V. | Acellular pertussis vaccine |
US9849066B2 (en) | 2013-04-24 | 2017-12-26 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
KR20160040290A (ko) | 2013-08-05 | 2016-04-12 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 조합 면역원성 조성물 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4070454A (en) * | 1973-05-04 | 1978-01-24 | Agence Nationale De Valorisation De La Recherche (Anvar) | Vaccines, the process for preparing the same and the applications thereof |
JPS5750925A (en) * | 1980-09-12 | 1982-03-25 | Takeda Chem Ind Ltd | Preparation of pertussis toxoid |
GB8601279D0 (en) * | 1986-01-20 | 1986-02-26 | Public Health Lab Service | Purification of pertussis antigens |
US4888169A (en) * | 1986-10-14 | 1989-12-19 | Norden Laboratories, Inc. | Bordetella Bronchiseptica vaccine |
WO1990009444A1 (en) * | 1989-02-10 | 1990-08-23 | Genesit Oy | A method for producing pertussis toxin subunits |
-
1991
- 1991-02-07 EP EP91903336A patent/EP0515415B1/en not_active Expired - Lifetime
- 1991-02-07 AU AU72110/91A patent/AU646019B2/en not_active Expired
- 1991-02-07 DE DE69113991T patent/DE69113991T2/de not_active Expired - Lifetime
- 1991-02-07 AT AT91903336T patent/ATE129159T1/de not_active IP Right Cessation
- 1991-02-07 ES ES91903336T patent/ES2080941T3/es not_active Expired - Lifetime
- 1991-02-07 DK DK91903336.5T patent/DK0515415T3/da active
- 1991-02-07 CA CA002075711A patent/CA2075711C/en not_active Expired - Lifetime
- 1991-02-07 JP JP03503734A patent/JP3035712B2/ja not_active Expired - Lifetime
- 1991-02-07 CY CY193591A patent/CY1935A/xx unknown
- 1991-02-07 WO PCT/EP1991/000257 patent/WO1991012020A1/en active IP Right Grant
- 1991-02-08 ZA ZA91947A patent/ZA91947B/xx unknown
- 1991-02-08 IE IE42491A patent/IE70672B1/en not_active IP Right Cessation
- 1991-02-08 PT PT96723A patent/PT96723B/pt not_active IP Right Cessation
- 1991-02-11 NZ NZ237069A patent/NZ237069A/en unknown
-
1992
- 1992-08-11 KR KR1019920701931A patent/KR100202052B1/ko not_active IP Right Cessation
-
1995
- 1995-12-15 GR GR950403570T patent/GR3018440T3/el unknown
-
1998
- 1998-04-28 HK HK98103622A patent/HK1004524A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0515415B1 (en) | 1995-10-18 |
CY1935A (en) | 1991-02-07 |
AU7211091A (en) | 1991-09-03 |
HK1004524A1 (en) | 1998-11-27 |
IE70672B1 (en) | 1996-12-11 |
KR100202052B1 (ko) | 1999-06-15 |
WO1991012020A1 (en) | 1991-08-22 |
ATE129159T1 (de) | 1995-11-15 |
DE69113991T2 (de) | 1996-03-21 |
DK0515415T3 (da) | 1995-11-27 |
PT96723B (pt) | 1998-07-31 |
JP3035712B2 (ja) | 2000-04-24 |
KR920703099A (ko) | 1992-12-17 |
JPH05503936A (ja) | 1993-06-24 |
CA2075711C (en) | 2000-11-07 |
NZ237069A (en) | 1993-07-27 |
DE69113991D1 (de) | 1995-11-23 |
ZA91947B (en) | 1992-01-29 |
EP0515415A1 (en) | 1992-12-02 |
AU646019B2 (en) | 1994-02-03 |
CA2075711A1 (en) | 1991-08-13 |
GR3018440T3 (en) | 1996-03-31 |
ES2080941T3 (es) | 1996-02-16 |
IE910424A1 (en) | 1991-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO1997010I1 (no) | Bordetella pertussis P69 antigen | |
PT96723A (pt) | Metodo para a destoxificacao de um antigenio toxico | |
DE69022106D1 (de) | Pertussistoxin-Mutanten, dieselbe produzierende Bordetella-Stämme und ihre Verwendung als Vakzin gegen Pertussis. | |
DE3785157D1 (de) | Verfahren zur herstellung von toxoid. | |
NO872919L (no) | Fremstilling av pertussis-toksin ved dyrkning av bodella pertussis. | |
DK520480A (da) | Fremgangsmaade til fremstilling af 2,3-dihydro2,2-dimethyl-7-hydroxybenzofuran | |
ES523264A0 (es) | Procedimiento para la preparacion de 2-(3-piridil)-1,3,4-oxadiazoles | |
DE68917709D1 (de) | Verfahren zur Herstellung eines Pertussis-Toxin-Toxoides. | |
FI884960A (fi) | Anvaendning av 2-pyrimidinyl-1-piperazin-derivat. | |
DE68917972D1 (de) | Pertussistoxoid-Impfstoff. | |
DK0454494T3 (da) | Calicheamicinoner, derivater deraf og analoge dertil og fremgangsmåde til fremstilling af disse | |
SE7801527L (sv) | 2,4-diklorfenyl-triazolyl-etan-oner(oler) till anvendning som fungicider och sett att framstella foreningarna | |
FR2601250B1 (fr) | Procede de preparation de fractions antigeniques exocellulaires de bordetella pertussis et vaccin contre la coqueluche contenant de telles fractions. | |
JPS5359023A (en) | Inactivation of toxins produced by microbials and attenuation of vaccines | |
JPS53109912A (en) | Condensed tannin, inactivation of microorganism-originated toxic substance, and attenuation of vaccines using condensed tannin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19910702 |
|
FG3A | Patent granted, date of granting |
Effective date: 19980406 |
|
MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20130408 |