DK0454494T3 - Calicheamicinoner, derivater deraf og analoge dertil og fremgangsmåde til fremstilling af disse - Google Patents
Calicheamicinoner, derivater deraf og analoge dertil og fremgangsmåde til fremstilling af disseInfo
- Publication number
- DK0454494T3 DK0454494T3 DK91303818.8T DK91303818T DK0454494T3 DK 0454494 T3 DK0454494 T3 DK 0454494T3 DK 91303818 T DK91303818 T DK 91303818T DK 0454494 T3 DK0454494 T3 DK 0454494T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- calicheamicinones
- analogues
- preparation
- calicheamicinone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51520990A | 1990-04-27 | 1990-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0454494T3 true DK0454494T3 (da) | 1995-12-04 |
Family
ID=24050400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91303818.8T DK0454494T3 (da) | 1990-04-27 | 1991-04-26 | Calicheamicinoner, derivater deraf og analoge dertil og fremgangsmåde til fremstilling af disse |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0454494B1 (da) |
| JP (1) | JPH04279544A (da) |
| AT (1) | ATE128113T1 (da) |
| CA (1) | CA2039789A1 (da) |
| DE (1) | DE69113102T2 (da) |
| DK (1) | DK0454494T3 (da) |
| ES (1) | ES2079569T3 (da) |
| GR (1) | GR3017912T3 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997041109A1 (en) * | 1996-04-26 | 1997-11-06 | University Of Alberta | Synthesis of (±) - calicheamicinone, precursors, intermediates and derivatives |
| PL229487B1 (pl) | 2002-11-12 | 2018-07-31 | Brigham & Womens Hospital Inc | Kompozycja zawierająca polimer β-1,6-glukozaminy, kompozycja zawierająca przeciwciało, kompozycja farmaceutyczna, sposób wytwarzania wyodrębnionego polisacharydu, sposób identyfikacji obecności deacetylowanej poli-N-acetyloglukozaminy (dPNAG) i/ lub poli-N-acetyloglukozaminy (PNAG), wyodrębniony polisacharyd do zastosowania w leczeniu lub profilaktyce zakażenia, wyodrębniony polisacharyd do zastosowania do wytwarzania przeciwciał, w tym przeciwciał monoklonalnych, wyodrębniony polisacharyd do zastosowania w identyfikacji przeciwciała monoklonalnego |
| NZ591103A (en) | 2008-07-21 | 2013-02-22 | Brigham & Womens Hospital | Methods and compositions relating to synthetic beta-1,6 glucosamine oligosaccharides |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL79519A0 (en) * | 1985-08-27 | 1986-10-31 | Bristol Myers Co | Bbm-1675c and d antitumor antibiotics |
| US4837206A (en) * | 1987-04-29 | 1989-06-06 | Bristol-Myers Company | Esperamicin derivatives |
-
1991
- 1991-04-04 CA CA002039789A patent/CA2039789A1/en not_active Abandoned
- 1991-04-26 AT AT91303818T patent/ATE128113T1/de not_active IP Right Cessation
- 1991-04-26 DK DK91303818.8T patent/DK0454494T3/da active
- 1991-04-26 EP EP91303818A patent/EP0454494B1/en not_active Expired - Lifetime
- 1991-04-26 ES ES91303818T patent/ES2079569T3/es not_active Expired - Lifetime
- 1991-04-26 DE DE69113102T patent/DE69113102T2/de not_active Expired - Fee Related
- 1991-04-30 JP JP3099289A patent/JPH04279544A/ja active Pending
-
1995
- 1995-10-30 GR GR950403011T patent/GR3017912T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2079569T3 (es) | 1996-01-16 |
| DE69113102T2 (de) | 1996-03-28 |
| GR3017912T3 (en) | 1996-01-31 |
| ATE128113T1 (de) | 1995-10-15 |
| EP0454494A2 (en) | 1991-10-30 |
| CA2039789A1 (en) | 1991-10-28 |
| EP0454494A3 (en) | 1993-05-26 |
| EP0454494B1 (en) | 1995-09-20 |
| DE69113102D1 (de) | 1995-10-26 |
| JPH04279544A (ja) | 1992-10-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IS3412A7 (is) | Hliðstæðuaðferð til framleiðslu á cytidine-afleiðum | |
| DK146489A (da) | Fremgangsmaade til fremstilling af 2',3'-dideoxy-2',3'-didehydronucleosider | |
| DK54090A (da) | Fremgangsmaade og apparat til fremstilling af krumme formstofboejler, isaer busteholderboejler | |
| ATE121008T1 (de) | Zweistufiges verfahren zum herstellen starker, dünner schlauchblasfolien. | |
| DK379985A (da) | Fremgangsmaade til fremstilling af 6-chlor-n-methyl-2,3,4,5-tetrahydro-lh-benzazepin | |
| DK540984A (da) | Fremgangsmaade til fremstilling af 1,2,4-triazolo-(1,5-a)pyrimidin-2-sulfonylchlorider | |
| DK0417680T3 (da) | Fremgangsmåde til fremstilling af 1,1,1,2-tetrafluorethan | |
| DK0454494T3 (da) | Calicheamicinoner, derivater deraf og analoge dertil og fremgangsmåde til fremstilling af disse | |
| DE3882831D1 (de) | Verfahren, um gemusterte duennschichtige zinnoxidbestandteile herzustellen. | |
| MX9204520A (es) | Proceso para la preparacion de natamicina por fermentacion (caso ch 2074). | |
| DE68912809T2 (de) | Verfahren zur Herstellung von Bis(2,2,6,6-tetramethyl-4-piperidyl)amin. | |
| DK113483A (da) | Fremgangsmaade til fremstilling af 3,4-diphenyl-5-methylpyrazolderivater | |
| DK0465373T3 (da) | Fremgangsmåde til fremstilling af kappa-carragenaner | |
| DE472182T1 (de) | Apparat zum aufrichten von schachtelzuschnitten. | |
| MX9101541A (es) | Un proceso(ii)para la preparacion de 5-aroilo-2,3-dihidro-1h-pirrolicina-1,1-dicarboxilatos | |
| DK700688D0 (da) | Fremgangsmaade til fremstilling af 2,4- eller 2,4,5,-substituerede 6-hydroxypyrimidiner | |
| DK417787A (da) | Fremgangsmaade til fremstilling af 7-oxo-4-thia-1-azabicyclo-(3,2,0)hept-2-en-derivater | |
| DK152131C (da) | Fremgangsmaade til fremstilling af 5,6,7,7a-tetrahydro-4h-thieno(3,2-c)-pyridin-2-on-derivater | |
| FI951581A0 (fi) | Menetelmä 9-aminokamptotesiinin valmistamiseksi | |
| DK513580A (da) | Fremgangsmaade til fremstilling af 4,5-diaryl-alfa (polyhalogenalkyl)-1h-imidazol-2-methanoler | |
| FI94533B (fi) | Menetelmä uuden antibiootin N-asetyylibenanomisiini B:n valmistamiseksi | |
| DK145080A (da) | Fremgangsmaade til fremstilling af aminoderivater af 2-hydroxy-6,9-methano-11-amino-5,6,7,8,9,10-hexahydrobenzocycloocten | |
| DK0377437T3 (da) | Fremgangsmåde til fremstilling af 2,4-diamino-6-piperidinylpyrimidin-3-N-oxid | |
| DK340488D0 (da) | Fremgangsmaade til fremstilling af enkeltkaedet urokinase | |
| DK95391D0 (da) | Fremgangsmaade til fremstilling af hydrogenholdig gas |