PT96142A - Processo para a preparacao de derivados de 3-fenilglutarimida antagonistas de receptores muscarinicos - Google Patents

Processo para a preparacao de derivados de 3-fenilglutarimida antagonistas de receptores muscarinicos

Info

Publication number
PT96142A
PT96142A PT96142A PT9614290A PT96142A PT 96142 A PT96142 A PT 96142A PT 96142 A PT96142 A PT 96142A PT 9614290 A PT9614290 A PT 9614290A PT 96142 A PT96142 A PT 96142A
Authority
PT
Portugal
Prior art keywords
alkyl
pct
independently
phenylglutarimide
preparation
Prior art date
Application number
PT96142A
Other languages
English (en)
Other versions
PT96142B (pt
Inventor
Peter Edward Cross
Alexander Roderick Mackenzie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT96142A publication Critical patent/PT96142A/pt
Publication of PT96142B publication Critical patent/PT96142B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • C07D211/88Oxygen atoms attached in positions 2 and 6, e.g. glutarimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT96142A 1989-12-12 1990-12-10 Processo para a preparacao de derivados de 3-fenilglutarimida antagonistas de receptores muscarinicos PT96142B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898928043A GB8928043D0 (en) 1989-12-12 1989-12-12 Muscarinic receptor antagonists

Publications (2)

Publication Number Publication Date
PT96142A true PT96142A (pt) 1991-09-30
PT96142B PT96142B (pt) 1997-05-28

Family

ID=10667814

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96142A PT96142B (pt) 1989-12-12 1990-12-10 Processo para a preparacao de derivados de 3-fenilglutarimida antagonistas de receptores muscarinicos

Country Status (13)

Country Link
US (1) US5300516A (pt)
EP (1) EP0505379B1 (pt)
JP (1) JPH0686428B2 (pt)
AT (1) ATE108776T1 (pt)
CA (1) CA2067759C (pt)
DE (1) DE69010917T2 (pt)
DK (1) DK0505379T3 (pt)
ES (1) ES2057601T3 (pt)
FI (1) FI96024C (pt)
GB (1) GB8928043D0 (pt)
IE (1) IE63421B1 (pt)
PT (1) PT96142B (pt)
WO (1) WO1991009014A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9602516D0 (en) * 1996-02-08 1996-04-10 Chiroscience Ltd Racemisation
DE10002509A1 (de) 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
EA201891416A1 (ru) * 2015-12-14 2018-12-28 Айронвуд Фармасьютикалз, Инк. ПРИМЕНЕНИЕ СТИМУЛЯТОРОВ sGC ДЛЯ ЛЕЧЕНИЯ ДИСФУНКЦИИ ЖЕЛУДОЧНО-КИШЕЧНОГО СФИНКТЕРА

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664424A (en) * 1953-12-29 Dioxo-piperidines
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
BE632403A (pt) * 1962-05-17 1900-01-01
GB1455687A (en) * 1972-12-28 1976-11-17 Aspro Nicholas Ltd Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
GB8716338D0 (en) * 1987-07-10 1987-08-19 Nat Res Dev Anti-anxiogenic compositions

Also Published As

Publication number Publication date
FI922342A (fi) 1992-05-22
PT96142B (pt) 1997-05-28
CA2067759C (en) 1996-09-10
ATE108776T1 (de) 1994-08-15
IE904461A1 (en) 1991-06-19
ES2057601T3 (es) 1994-10-16
IE63421B1 (en) 1995-04-19
FI96024C (fi) 1996-04-25
CA2067759A1 (en) 1991-06-13
JPH04505926A (ja) 1992-10-15
EP0505379A1 (en) 1992-09-30
DK0505379T3 (da) 1994-09-12
DE69010917D1 (de) 1994-08-25
US5300516A (en) 1994-04-05
WO1991009014A1 (en) 1991-06-27
DE69010917T2 (de) 1994-11-03
FI922342A0 (fi) 1992-05-22
JPH0686428B2 (ja) 1994-11-02
FI96024B (fi) 1996-01-15
EP0505379B1 (en) 1994-07-20
GB8928043D0 (en) 1990-02-14

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910509

FG3A Patent granted, date of granting

Effective date: 19970307

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20040907